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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Isoprene |
CASRN: | ="78-79-5" |
Study Number: | C61825B |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | RESPIRATORY EXPOSURE WHOLE BODY |
TDMS Number: | 0513507 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (PPM) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 111 |
506 |
700 |
|
173.4 |
|
Day 114 |
741 |
7000 |
|
151.1 |
|
Day 370 |
336 |
220 |
|
194.3 |
|
Day 398 |
122 |
0 |
|
218.3 |
|
Day 415 |
707 |
7000 |
|
241.6 |
|
Day 427 |
530 |
700 |
|
213.8 |
|
Day 432 |
705 |
7000 |
|
244 |
|
Day 454 |
121 |
0 |
|
253.6 |
|
Day 464 |
747 |
7000 |
|
233.5 |
|
Day 482 |
109 |
0 |
|
354.7 |
|
Day 482 |
349 |
220 |
|
268.4 |
|
Day 482 |
719 |
7000 |
|
211.6 |
|
Day 490 |
750 |
7000 |
|
252 |
|
Day 497 |
716 |
7000 |
|
212.2 |
|
Day 508 |
502 |
700 |
|
263.3 |
|
Day 510 |
521 |
700 |
|
216.5 |
|
Day 539 |
139 |
0 |
|
239.9 |
|
Day 539 |
537 |
700 |
|
407.1 |
|
Day 547 |
525 |
700 |
|
238.5 |
|
Day 552 |
115 |
0 |
|
223.2 |
|
Day 566 |
501 |
700 |
|
239.3 |
|
Day 580 |
125 |
0 |
|
299.1 |
|
Day 580 |
136 |
0 |
|
270.2 |
|
Day 580 |
524 |
700 |
|
261.9 |
|
Day 581 |
528 |
700 |
|
285.5 |
|
Day 587 |
308 |
220 |
|
332.3 |
|
Day 594 |
724 |
7000 |
|
260.5 |
|
Day 594 |
738 |
7000 |
|
275.7 |
|
Day 596 |
108 |
0 |
|
221.8 |
|
Day 601 |
301 |
220 |
|
341 |
|
Day 602 |
305 |
220 |
|
275.3 |
|
Day 604 |
545 |
700 |
|
293.8 |
|
Day 611 |
539 |
700 |
|
290.2 |
|
Day 617 |
509 |
700 |
|
248.2 |
|
Day 621 |
709 |
7000 |
|
281.7 |
|
Day 622 |
314 |
220 |
|
239 |
|
Day 625 |
711 |
7000 |
|
394 |
|
Day 626 |
326 |
220 |
|
283.6 |
|
Day 629 |
126 |
0 |
|
252.8 |
|
Day 630 |
101 |
0 |
|
344.1 |
|
Day 630 |
739 |
7000 |
|
240.1 |
|
Day 638 |
337 |
220 |
|
231.2 |
|
Day 638 |
540 |
700 |
|
290.8 |
|
Day 643 |
340 |
220 |
|
292.6 |
|
Day 648 |
137 |
0 |
|
212 |
|
Day 652 |
726 |
7000 |
|
255.6 |
|
Day 653 |
740 |
7000 |
|
274 |
|
Day 657 |
131 |
0 |
|
261.7 |
|
Day 657 |
134 |
0 |
|
238.3 |
|
Day 664 |
330 |
220 |
|
295.3 |
|
Day 664 |
702 |
7000 |
|
292.4 |
|
Day 664 |
710 |
7000 |
|
237.9 |
|
Day 670 |
150 |
0 |
|
234 |
|
Day 670 |
304 |
220 |
|
480.5 |
|
Day 670 |
329 |
220 |
|
217.5 |
|
Day 671 |
132 |
0 |
|
397.6 |
|
Day 672 |
548 |
700 |
|
264.3 |
|
Day 681 |
729 |
7000 |
|
265.3 |
|
Day 681 |
746 |
7000 |
|
350.3 |
|
Day 684 |
102 |
0 |
|
324.4 |
|
Day 685 |
309 |
220 |
|
314.5 |
|
Day 686 |
335 |
220 |
|
321 |
|
Day 693 |
327 |
220 |
|
237.4 |
|
Day 694 |
324 |
220 |
|
290 |
|
Day 695 |
316 |
220 |
|
260.6 |
|
Day 699 |
523 |
700 |
|
302.9 |
|
Day 705 |
133 |
0 |
|
347.3 |
|
Day 708 |
547 |
700 |
|
250.8 |
|
Day 709 |
737 |
7000 |
|
337.2 |
|
Day 710 |
512 |
700 |
|
310.1 |
|
Day 710 |
543 |
700 |
|
246.2 |
|
Day 713 |
510 |
700 |
|
263.3 |
|
Day 713 |
732 |
7000 |
|
224.8 |
|
Day 713 |
742 |
7000 |
|
244.3 |
|
Day 714 |
141 |
0 |
|
|
|
Day 714 |
346 |
220 |
|
314.9 |
|
Day 714 |
701 |
7000 |
|
386.2 |
|
Day 721 |
531 |
700 |
|
226.7 |
|
Day 723 |
538 |
700 |
|
239.2 |
|
Day 727 |
128 |
0 |
|
266.2 |
|
Day 727 |
142 |
0 |
|
277.4 |
|
Day 727 |
325 |
220 |
|
325.8 |
|
Day 727 |
338 |
220 |
|
237.2 |
|
Day 727 |
514 |
700 |
|
367.5 |
|
Day 727 |
734 |
7000 |
|
257.8 |
|
Day 728 |
129 |
0 |
|
239.2 |
|
Day 734 |
103 |
0 |
|
349.3 |
|
Day 734 |
110 |
0 |
|
304.1 |
|
Day 734 |
111 |
0 |
|
391.2 |
|
Day 734 |
112 |
0 |
|
312 |
|
Day 734 |
117 |
0 |
|
413.3 |
|
Day 734 |
119 |
0 |
|
339.1 |
|
Day 734 |
120 |
0 |
|
346.6 |
|
Day 734 |
123 |
0 |
|
385.7 |
|
Day 734 |
135 |
0 |
|
344.9 |
|
Day 734 |
140 |
0 |
|
366.1 |
|
Day 734 |
143 |
0 |
|
359.6 |
|
Day 734 |
146 |
0 |
|
437.2 |
|
Day 734 |
306 |
220 |
|
366.2 |
|
Day 734 |
310 |
220 |
|
321.9 |
|
Day 734 |
321 |
220 |
|
347.4 |
|
Day 734 |
331 |
220 |
|
383 |
|
Day 734 |
345 |
220 |
|
382.4 |
|
Day 734 |
348 |
220 |
|
298.6 |
|
Day 734 |
513 |
700 |
|
328.2 |
|
Day 734 |
516 |
700 |
|
329.1 |
|
Day 734 |
517 |
700 |
|
300.4 |
|
Day 734 |
532 |
700 |
|
301.2 |
|
Day 734 |
536 |
700 |
|
389.9 |
|
Day 734 |
708 |
7000 |
|
358.5 |
|
Day 734 |
720 |
7000 |
|
339.7 |
|
Day 734 |
722 |
7000 |
|
346.8 |
|
Day 734 |
725 |
7000 |
|
334.4 |
|
Day 734 |
735 |
7000 |
|
328.5 |
|
Day 734 |
736 |
7000 |
|
353.2 |
|
Day 734 |
748 |
7000 |
|
228.6 |
|
Day 735 |
104 |
0 |
|
405 |
|
Day 735 |
105 |
0 |
|
403.6 |
|
Day 735 |
106 |
0 |
|
374.4 |
|
Day 735 |
107 |
0 |
|
377.6 |
|
Day 735 |
114 |
0 |
|
350.7 |
|
Day 735 |
118 |
0 |
|
374.3 |
|
Day 735 |
124 |
0 |
|
362.5 |
|
Day 735 |
145 |
0 |
|
374.4 |
|
Day 735 |
147 |
0 |
|
339.4 |
|
Day 735 |
148 |
0 |
|
351.5 |
|
Day 735 |
311 |
220 |
|
355.6 |
|
Day 735 |
312 |
220 |
|
392.9 |
|
Day 735 |
315 |
220 |
|
381.1 |
|
Day 735 |
317 |
220 |
|
400 |
|
Day 735 |
318 |
220 |
|
347.6 |
|
Day 735 |
320 |
220 |
|
357.5 |
|
Day 735 |
328 |
220 |
|
289.1 |
|
Day 735 |
339 |
220 |
|
479.3 |
|
Day 735 |
343 |
220 |
|
421 |
|
Day 735 |
344 |
220 |
|
366.9 |
|
Day 735 |
503 |
700 |
|
420.7 |
|
Day 735 |
504 |
700 |
|
318.3 |
|
Day 735 |
505 |
700 |
|
372.8 |
|
Day 735 |
507 |
700 |
|
403.9 |
|
Day 735 |
508 |
700 |
|
354 |
|
Day 735 |
511 |
700 |
|
404.8 |
|
Day 735 |
518 |
700 |
|
363.9 |
|
Day 735 |
520 |
700 |
|
433.7 |
|
Day 735 |
526 |
700 |
|
352.5 |
|
Day 735 |
534 |
700 |
|
399.3 |
|
Day 735 |
535 |
700 |
|
370.3 |
|
Day 735 |
541 |
700 |
|
369.2 |
|
Day 735 |
546 |
700 |
|
358.8 |
|
Day 735 |
550 |
700 |
|
454.6 |
|
Day 735 |
704 |
7000 |
|
350.2 |
|
Day 735 |
712 |
7000 |
|
320.5 |
|
Day 735 |
713 |
7000 |
|
375.5 |
|
Day 735 |
714 |
7000 |
|
343.4 |
|
Day 735 |
715 |
7000 |
|
335.2 |
|
Day 735 |
717 |
7000 |
|
375.9 |
|
Day 735 |
721 |
7000 |
|
378.8 |
|
Day 735 |
723 |
7000 |
|
398.9 |
|
Day 735 |
731 |
7000 |
|
374.6 |
|
Day 735 |
733 |
7000 |
|
342.5 |
|
Day 735 |
743 |
7000 |
|
379.5 |
|
Day 735 |
745 |
7000 |
|
435.4 |
|
Day 735 |
749 |
7000 |
|
406.1 |
|
Day 736 |
113 |
0 |
|
300.6 |
|
Day 736 |
116 |
0 |
|
374.4 |
|
Day 736 |
127 |
0 |
|
338.9 |
|
Day 736 |
130 |
0 |
|
306.2 |
|
Day 736 |
138 |
0 |
|
351.4 |
|
Day 736 |
144 |
0 |
|
327.9 |
|
Day 736 |
149 |
0 |
|
366.7 |
|
Day 736 |
302 |
220 |
|
373.7 |
|
Day 736 |
303 |
220 |
|
352 |
|
Day 736 |
307 |
220 |
|
305.7 |
|
Day 736 |
313 |
220 |
|
339.6 |
|
Day 736 |
319 |
220 |
|
333.8 |
|
Day 736 |
322 |
220 |
|
377.7 |
|
Day 736 |
323 |
220 |
|
403.8 |
|
Day 736 |
332 |
220 |
|
316.8 |
|
Day 736 |
333 |
220 |
|
367.5 |
|
Day 736 |
334 |
220 |
|
290.2 |
|
Day 736 |
341 |
220 |
|
335.3 |
|
Day 736 |
342 |
220 |
|
400.2 |
|
Day 736 |
347 |
220 |
|
364.7 |
|
Day 736 |
350 |
220 |
|
320.5 |
|
Day 736 |
515 |
700 |
|
390.2 |
|
Day 736 |
519 |
700 |
|
355.7 |
|
Day 736 |
522 |
700 |
|
401.6 |
|
Day 736 |
527 |
700 |
|
301.2 |
|
Day 736 |
529 |
700 |
|
370.6 |
|
Day 736 |
533 |
700 |
|
377.1 |
|
Day 736 |
542 |
700 |
|
401 |
|
Day 736 |
544 |
700 |
|
375.4 |
|
Day 736 |
549 |
700 |
|
376.5 |
|
Day 736 |
703 |
7000 |
|
359.4 |
|
Day 736 |
706 |
7000 |
|
341.5 |
|
Day 736 |
718 |
7000 |
|
330.4 |
|
Day 736 |
727 |
7000 |
|
321 |
|
Day 736 |
728 |
7000 |
|
304.1 |
|
Day 736 |
730 |
7000 |
|
367.6 |
|
Day 736 |
744 |
7000 |
|
403.7 |
|
Abbreviations: |
NA: Not Available
|