Alimentary System |
Liver |
|
0.2 % |
1 |
21 |
105 |
92 |
1 |
Hepatodiaphragmatic Nodule |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
13 |
63 |
92 |
1 |
Infiltration Cellular |
Minimal, Mononuclear Cl |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
14 |
66 |
92 |
1 |
Infiltration Cellular |
Minimal, Mononuclear Cl |
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
Vehicle Control |
10 |
14 |
66 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
10 |
13 |
62 |
92 |
1 |
Cardiomyopathy |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
|
Vehicle Control |
10 |
13 |
63 |
92 |
1 |
Ectopic Thymus |
Minimal |
Terminal Sacrifice |
General Body System |
Tissue NOS |
Abdominal, Fat |
0.4 % |
1 |
23 |
111 |
92 |
1 |
Necrosis |
Minimal, Focal |
Terminal Sacrifice |
Genital System |
Ovary |
|
0.05 % |
2 |
18 |
88 |
92 |
1 |
Cyst |
Mild |
Terminal Sacrifice |
Genital System |
Ovary |
|
0.1 % |
1 |
19 |
92 |
92 |
1 |
Cyst |
Mild |
Terminal Sacrifice |
Genital System |
Ovary |
|
0.2 % |
2 |
22 |
106 |
92 |
1 |
Cyst |
Mild |
Terminal Sacrifice |
Genital System |
Uterus |
|
Vehicle Control |
10 |
13 |
63 |
92 |
1 |
Hydrometra |
Mild |
Terminal Sacrifice |
Genital System |
Uterus |
|
0.4 % |
10 |
23 |
111 |
92 |
1 |
Hydrometra |
Mild |
Terminal Sacrifice |
Genital System |
Uterus |
|
0.4 % |
10 |
23 |
115 |
92 |
1 |
Hydrometra |
Minimal |
Terminal Sacrifice |
Genital System |
Uterus |
|
0.4 % |
10 |
24 |
117 |
92 |
1 |
Hydrometra |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
10 |
14 |
68 |
92 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.025 % |
2 |
15 |
73 |
92 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.025 % |
2 |
16 |
78 |
92 |
1 |
Congestion |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.05 % |
2 |
17 |
84 |
92 |
1 |
Congestion |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.05 % |
2 |
18 |
88 |
92 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.1 % |
2 |
19 |
92 |
92 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.2 % |
3 |
21 |
104 |
92 |
1 |
Congestion |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.2 % |
3 |
21 |
105 |
92 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.2 % |
3 |
22 |
108 |
92 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
10 |
14 |
68 |
92 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.025 % |
2 |
15 |
73 |
92 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.025 % |
2 |
16 |
78 |
92 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.05 % |
2 |
17 |
84 |
92 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.05 % |
2 |
18 |
88 |
92 |
1 |
Hyperplasia |
Minimal, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.1 % |
2 |
19 |
92 |
92 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.1 % |
2 |
20 |
100 |
92 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.2 % |
3 |
21 |
104 |
92 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.2 % |
3 |
21 |
105 |
92 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.2 % |
3 |
22 |
108 |
92 |
1 |
Hyperplasia |
Moderate, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
0.4 % |
10 |
24 |
117 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
0.4 % |
10 |
24 |
116 |
92 |
1 |
Necrosis |
Minimal, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
0.4 % |
10 |
24 |
116 |
92 |
1 |
Necrosis |
Minimal, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
0.4 % |
10 |
24 |
118 |
92 |
1 |
Necrosis |
Minimal, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
13 |
61 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
13 |
64 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
14 |
67 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
14 |
68 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
23 |
112 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
23 |
113 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
23 |
115 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
24 |
117 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
13 |
62 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
13 |
63 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
13 |
65 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
14 |
66 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
14 |
69 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
14 |
70 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
23 |
111 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
23 |
114 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
24 |
116 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
24 |
118 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
24 |
119 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
0.4 % |
10 |
24 |
120 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
10 |
14 |
66 |
92 |
1 |
Hemorrhage |
Minimal, Focal |
Terminal Sacrifice |
Respiratory System |
Lung |
|
0.4 % |
10 |
24 |
118 |
92 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
Vehicle Control |
10 |
13 |
61 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
Vehicle Control |
10 |
13 |
64 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
Vehicle Control |
10 |
14 |
69 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.05 % |
10 |
17 |
81 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.05 % |
10 |
18 |
86 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.05 % |
10 |
18 |
88 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.1 % |
10 |
19 |
91 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.1 % |
10 |
20 |
100 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.1 % |
10 |
20 |
96 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.2 % |
10 |
21 |
102 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.2 % |
10 |
22 |
106 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.2 % |
10 |
22 |
109 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.4 % |
10 |
23 |
111 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.4 % |
10 |
23 |
112 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.4 % |
10 |
23 |
113 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.4 % |
10 |
24 |
116 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.4 % |
10 |
24 |
117 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.4 % |
10 |
24 |
118 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Goblet Cell, Respirat Epith |
0.4 % |
10 |
24 |
119 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Respirat Epith |
0.2 % |
10 |
22 |
109 |
92 |
1 |
Inflammation |
Minimal, Acute |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
10 |
13 |
63 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
10 |
14 |
68 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
10 |
14 |
70 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.025 % |
10 |
15 |
74 |
92 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.025 % |
10 |
16 |
76 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.05 % |
10 |
17 |
82 |
92 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.05 % |
10 |
18 |
88 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.1 % |
10 |
19 |
95 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.1 % |
10 |
20 |
96 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.2 % |
10 |
22 |
106 |
92 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.4 % |
10 |
23 |
111 |
92 |
1 |
Necrosis |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.4 % |
10 |
23 |
115 |
92 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
0.4 % |
10 |
24 |
116 |
92 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
0.4 % |
10 |
23 |
113 |
92 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
10 |
14 |
70 |
92 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |