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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Nickel subsulfide |
CASRN: | ="12035-72-2" |
Study Number: | C61654 |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | |
TDMS Number: | 0510705 |
Sex: | Male |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (MG/M3) |
Control Code |
Final Body Weight (g) |
Day 199 |
1 |
0 |
|
378.8 |
Day 199 |
14 |
0 |
|
407.4 |
Day 199 |
2 |
0 |
|
374 |
Day 199 |
20 |
0 |
|
415.5 |
Day 199 |
24 |
0 |
|
391.7 |
Day 199 |
33 |
0 |
|
395.7 |
Day 199 |
35 |
0 |
|
371.2 |
Day 199 |
46 |
0 |
|
441.9 |
Day 199 |
50 |
0 |
|
388.2 |
Day 199 |
58 |
0 |
|
420 |
Day 199 |
59 |
0 |
|
388 |
Day 199 |
68 |
0 |
|
416.2 |
Day 199 |
147 |
0.15 |
|
348.7 |
Day 199 |
150 |
0.15 |
|
353.3 |
Day 199 |
158 |
0.15 |
|
379.2 |
Day 199 |
171 |
0.15 |
|
405.7 |
Day 199 |
176 |
0.15 |
|
422.6 |
Day 199 |
182 |
0.15 |
|
387.9 |
Day 199 |
185 |
0.15 |
|
400.6 |
Day 199 |
189 |
0.15 |
|
394.1 |
Day 199 |
196 |
0.15 |
|
415.4 |
Day 199 |
198 |
0.15 |
|
403.8 |
Day 199 |
200 |
0.15 |
|
423.7 |
Day 199 |
204 |
0.15 |
|
373.3 |
Day 199 |
281 |
1.0 |
|
348.7 |
Day 199 |
285 |
1.0 |
|
390.2 |
Day 199 |
287 |
1.0 |
|
387.4 |
Day 199 |
293 |
1.0 |
|
353.7 |
Day 199 |
306 |
1.0 |
|
413 |
Day 199 |
319 |
1.0 |
|
376 |
Day 199 |
322 |
1.0 |
|
365.4 |
Day 199 |
324 |
1.0 |
|
361 |
Day 199 |
326 |
1.0 |
|
381.6 |
Day 199 |
331 |
1.0 |
|
352.9 |
Day 199 |
344 |
1.0 |
|
412.4 |
Day 199 |
345 |
1.0 |
|
368.5 |
Day 257 |
32 |
0 |
|
226.5 |
Day 361 |
3 |
0 |
|
341.6 |
Day 373 |
22 |
0 |
|
467.4 |
Day 398 |
162 |
0.15 |
|
361.5 |
Day 408 |
347 |
1.0 |
|
307.6 |
Day 424 |
314 |
1.0 |
|
338.9 |
Day 455 |
188 |
0.15 |
|
355 |
Day 458 |
11 |
0 |
|
472.9 |
Day 458 |
28 |
0 |
|
467.8 |
Day 458 |
44 |
0 |
|
521.2 |
Day 458 |
5 |
0 |
|
449.8 |
Day 458 |
52 |
0 |
|
430.6 |
Day 458 |
153 |
0.15 |
|
476.6 |
Day 458 |
175 |
0.15 |
|
453.8 |
Day 458 |
178 |
0.15 |
|
443.3 |
Day 458 |
183 |
0.15 |
|
455 |
Day 458 |
186 |
0.15 |
|
482.9 |
Day 458 |
286 |
1.0 |
|
455.1 |
Day 458 |
292 |
1.0 |
|
465.9 |
Day 458 |
301 |
1.0 |
|
434.2 |
Day 458 |
332 |
1.0 |
|
415.7 |
Day 458 |
343 |
1.0 |
|
444.1 |
Day 509 |
310 |
1.0 |
|
374.7 |
Day 521 |
39 |
0 |
|
387.5 |
Day 527 |
302 |
1.0 |
|
457.5 |
Day 537 |
65 |
0 |
|
362.5 |
Day 538 |
174 |
0.15 |
|
453.7 |
Day 539 |
70 |
0 |
|
456 |
Day 542 |
48 |
0 |
|
377.2 |
Day 549 |
170 |
0.15 |
|
474 |
Day 552 |
164 |
0.15 |
|
390.9 |
Day 552 |
290 |
1.0 |
|
359.3 |
Day 553 |
43 |
0 |
|
506 |
Day 559 |
12 |
0 |
|
438.9 |
Day 559 |
36 |
0 |
|
422.8 |
Day 559 |
300 |
1.0 |
|
324.8 |
Day 560 |
340 |
1.0 |
|
388.6 |
Day 563 |
163 |
0.15 |
|
280.1 |
Day 564 |
338 |
1.0 |
|
333 |
Day 564 |
350 |
1.0 |
|
307 |
Day 565 |
67 |
0 |
|
390.4 |
Day 565 |
9 |
0 |
|
416.1 |
Day 569 |
173 |
0.15 |
|
366.2 |
Day 570 |
208 |
0.15 |
|
338.4 |
Day 572 |
57 |
0 |
|
368.4 |
Day 573 |
16 |
0 |
|
502.8 |
Day 574 |
41 |
0 |
|
497.5 |
Day 577 |
321 |
1.0 |
|
339.8 |
Day 578 |
7 |
0 |
|
331.4 |
Day 578 |
316 |
1.0 |
|
331.6 |
Day 584 |
348 |
1.0 |
|
367.7 |
Day 590 |
282 |
1.0 |
|
309.2 |
Day 594 |
8 |
0 |
|
521.5 |
Day 594 |
168 |
0.15 |
|
439 |
Day 594 |
207 |
0.15 |
|
478.8 |
Day 594 |
289 |
1.0 |
|
421 |
Day 595 |
172 |
0.15 |
|
351 |
Day 595 |
337 |
1.0 |
|
308 |
Day 596 |
60 |
0 |
|
412.4 |
Day 599 |
38 |
0 |
|
486.4 |
Day 599 |
145 |
0.15 |
|
454 |
Day 599 |
159 |
0.15 |
|
404.6 |
Day 601 |
190 |
0.15 |
|
336.7 |
Day 608 |
4 |
0 |
|
370.3 |
Day 608 |
157 |
0.15 |
|
403.8 |
Day 615 |
26 |
0 |
|
363 |
Day 621 |
315 |
1.0 |
|
332 |
Day 621 |
323 |
1.0 |
|
262 |
Day 623 |
151 |
0.15 |
|
370.8 |
Day 623 |
166 |
0.15 |
|
356.1 |
Day 623 |
305 |
1.0 |
|
379.1 |
Day 624 |
18 |
0 |
|
440 |
Day 624 |
177 |
0.15 |
|
417.9 |
Day 629 |
312 |
1.0 |
|
346.8 |
Day 634 |
45 |
0 |
|
367.7 |
Day 635 |
56 |
0 |
|
487.3 |
Day 638 |
142 |
0.15 |
|
369.4 |
Day 638 |
194 |
0.15 |
|
371 |
Day 639 |
62 |
0 |
|
464 |
Day 639 |
160 |
0.15 |
|
418.1 |
Day 639 |
187 |
0.15 |
|
428.5 |
Day 642 |
197 |
0.15 |
|
382.3 |
Day 642 |
325 |
1.0 |
|
347.4 |
Day 643 |
283 |
1.0 |
|
323.8 |
Day 648 |
284 |
1.0 |
|
364.3 |
Day 650 |
184 |
0.15 |
|
376.3 |
Day 650 |
320 |
1.0 |
|
465.3 |
Day 651 |
63 |
0 |
|
457.9 |
Day 657 |
29 |
0 |
|
365.9 |
Day 661 |
201 |
0.15 |
|
401 |
Day 663 |
304 |
1.0 |
|
340.5 |
Day 663 |
327 |
1.0 |
|
289.3 |
Day 664 |
19 |
0 |
|
362 |
Day 671 |
51 |
0 |
|
363.1 |
Day 678 |
47 |
0 |
|
347.9 |
Day 678 |
297 |
1.0 |
|
308.7 |
Day 683 |
30 |
0 |
|
407.3 |
Day 690 |
148 |
0.15 |
|
343 |
Day 691 |
21 |
0 |
|
416 |
Day 695 |
143 |
0.15 |
|
306.3 |
Day 696 |
13 |
0 |
|
324 |
Day 699 |
54 |
0 |
|
429.4 |
Day 700 |
154 |
0.15 |
|
378 |
Day 701 |
55 |
0 |
|
339 |
Day 703 |
295 |
1.0 |
|
313.4 |
Day 703 |
298 |
1.0 |
|
299 |
Day 703 |
349 |
1.0 |
|
281 |
Day 705 |
34 |
0 |
|
354.5 |
Day 706 |
25 |
0 |
|
325.6 |
Day 707 |
333 |
1.0 |
|
307.4 |
Day 711 |
288 |
1.0 |
|
371.3 |
Day 713 |
40 |
0 |
|
357.9 |
Day 713 |
199 |
0.15 |
|
384 |
Day 715 |
37 |
0 |
|
321 |
Day 716 |
330 |
1.0 |
|
356.4 |
Day 717 |
205 |
0.15 |
|
337.5 |
Day 718 |
149 |
0.15 |
|
287.8 |
Day 723 |
296 |
1.0 |
|
269.7 |
Day 726 |
342 |
1.0 |
|
251.1 |
Day 727 |
141 |
0.15 |
|
321 |
Day 728 |
69 |
0 |
|
416 |
Day 731 |
341 |
1.0 |
|
339 |
Day 733 |
10 |
0 |
|
461.6 |
Day 733 |
27 |
0 |
|
429.5 |
Day 733 |
42 |
0 |
|
459.7 |
Day 733 |
49 |
0 |
|
486.9 |
Day 733 |
144 |
0.15 |
|
469.8 |
Day 733 |
146 |
0.15 |
|
452 |
Day 733 |
155 |
0.15 |
|
442.7 |
Day 733 |
169 |
0.15 |
|
462.9 |
Day 733 |
191 |
0.15 |
|
458.9 |
Day 733 |
192 |
0.15 |
|
393.2 |
Day 733 |
203 |
0.15 |
|
464.6 |
Day 733 |
206 |
0.15 |
|
415 |
Day 733 |
209 |
0.15 |
|
437.4 |
Day 733 |
294 |
1.0 |
|
372.2 |
Day 733 |
307 |
1.0 |
|
302.9 |
Day 733 |
308 |
1.0 |
|
329.4 |
Day 733 |
309 |
1.0 |
|
313.7 |
Day 733 |
311 |
1.0 |
|
355.7 |
Day 733 |
313 |
1.0 |
|
368.5 |
Day 733 |
318 |
1.0 |
|
403.9 |
Day 733 |
329 |
1.0 |
|
329.5 |
Day 736 |
17 |
0 |
|
445.4 |
Day 736 |
23 |
0 |
|
413.6 |
Day 736 |
31 |
0 |
|
486.1 |
Day 736 |
6 |
0 |
|
335.3 |
Day 736 |
64 |
0 |
|
456.6 |
Day 736 |
66 |
0 |
|
466.4 |
Day 736 |
152 |
0.15 |
|
418.3 |
Day 736 |
156 |
0.15 |
|
487.2 |
Day 736 |
165 |
0.15 |
|
437 |
Day 736 |
167 |
0.15 |
|
386.2 |
Day 736 |
179 |
0.15 |
|
367.4 |
Day 736 |
180 |
0.15 |
|
430.3 |
Day 736 |
181 |
0.15 |
|
429.3 |
Day 736 |
193 |
0.15 |
|
437.5 |
Day 736 |
202 |
0.15 |
|
464.6 |
Day 736 |
291 |
1.0 |
|
464.7 |
Day 736 |
299 |
1.0 |
|
386.4 |
Day 736 |
303 |
1.0 |
|
367.1 |
Day 736 |
317 |
1.0 |
|
356.9 |
Day 736 |
335 |
1.0 |
|
400.6 |
Day 736 |
339 |
1.0 |
|
336.4 |
Day 736 |
346 |
1.0 |
|
460.3 |
Day 737 |
15 |
0 |
|
370.5 |
Day 737 |
53 |
0 |
|
439.2 |
Day 737 |
61 |
0 |
|
438 |
Day 737 |
161 |
0.15 |
|
451.7 |
Day 737 |
195 |
0.15 |
|
510.3 |
Day 737 |
210 |
0.15 |
|
319.2 |
Day 737 |
328 |
1.0 |
|
317.4 |
Day 737 |
334 |
1.0 |
|
342.8 |
Day 737 |
336 |
1.0 |
|
292.9 |
Abbreviations: |
NA: Not Available
|