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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Oxazepam |
CASRN: | ="604-75-1" |
Study Number: | C62453B |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | DOSED FEED |
TDMS Number: | 0521205 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (PPM) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 17 |
549 |
5000 |
|
105.9 |
|
Day 183 |
401 |
1250 |
|
|
|
Day 183 |
402 |
1250 |
|
|
|
Day 183 |
403 |
1250 |
|
|
|
Day 183 |
404 |
1250 |
|
|
|
Day 183 |
405 |
1250 |
|
|
|
Day 183 |
406 |
1250 |
|
|
|
Day 183 |
407 |
1250 |
|
|
|
Day 183 |
408 |
1250 |
|
|
|
Day 183 |
409 |
1250 |
|
|
|
Day 183 |
410 |
1250 |
|
|
|
Day 183 |
411 |
1250 |
|
|
|
Day 183 |
412 |
1250 |
|
|
|
Day 183 |
413 |
1250 |
|
|
|
Day 183 |
414 |
1250 |
|
|
|
Day 183 |
415 |
1250 |
|
|
|
Day 183 |
416 |
1250 |
|
|
|
Day 183 |
417 |
1250 |
|
|
|
Day 183 |
418 |
1250 |
|
|
|
Day 183 |
419 |
1250 |
|
|
|
Day 183 |
420 |
1250 |
|
|
|
Day 183 |
421 |
1250 |
|
|
|
Day 183 |
422 |
1250 |
|
|
|
Day 183 |
423 |
1250 |
|
|
|
Day 183 |
424 |
1250 |
|
|
|
Day 183 |
425 |
1250 |
|
|
|
Day 183 |
426 |
1250 |
|
|
|
Day 183 |
427 |
1250 |
|
|
|
Day 183 |
428 |
1250 |
|
|
|
Day 183 |
429 |
1250 |
|
|
|
Day 183 |
430 |
1250 |
|
|
|
Day 183 |
431 |
1250 |
|
|
|
Day 183 |
432 |
1250 |
|
|
|
Day 183 |
433 |
1250 |
|
|
|
Day 183 |
434 |
1250 |
|
|
|
Day 183 |
435 |
1250 |
|
|
|
Day 183 |
436 |
1250 |
|
|
|
Day 183 |
437 |
1250 |
|
|
|
Day 183 |
438 |
1250 |
|
|
|
Day 183 |
439 |
1250 |
|
|
|
Day 183 |
440 |
1250 |
|
|
|
Day 183 |
441 |
1250 |
|
|
|
Day 183 |
442 |
1250 |
|
|
|
Day 183 |
443 |
1250 |
|
|
|
Day 183 |
444 |
1250 |
|
|
|
Day 183 |
445 |
1250 |
|
|
|
Day 183 |
446 |
1250 |
|
|
|
Day 183 |
447 |
1250 |
|
|
|
Day 183 |
448 |
1250 |
|
|
|
Day 183 |
449 |
1250 |
|
|
|
Day 183 |
450 |
1250 |
|
|
|
Day 223 |
301 |
0 |
|
229.3 |
|
Day 228 |
322 |
0 |
|
209.5 |
|
Day 288 |
390 |
625 |
|
215.1 |
|
Day 400 |
380 |
625 |
|
198.4 |
|
Day 413 |
523 |
5000 |
|
186.8 |
|
Day 414 |
477 |
2500 |
|
233.1 |
|
Day 432 |
489 |
2500 |
|
230.6 |
|
Day 453 |
484 |
2500 |
|
243.8 |
|
Day 475 |
384 |
625 |
|
325.6 |
|
Day 478 |
358 |
625 |
|
217.2 |
|
Day 478 |
564 |
10,000 |
|
256.9 |
|
Day 506 |
488 |
2500 |
|
214.6 |
|
Day 506 |
596 |
10,000 |
|
209.7 |
|
Day 522 |
305 |
0 |
|
199 |
|
Day 529 |
304 |
0 |
|
372.6 |
|
Day 539 |
461 |
2500 |
|
225.9 |
|
Day 540 |
468 |
2500 |
|
184.7 |
|
Day 550 |
341 |
0 |
|
280 |
|
Day 550 |
381 |
625 |
|
223.6 |
|
Day 550 |
471 |
2500 |
|
219 |
|
Day 550 |
538 |
5000 |
|
322.2 |
|
Day 556 |
479 |
2500 |
|
195 |
|
Day 562 |
563 |
10,000 |
|
272.6 |
|
Day 562 |
570 |
10,000 |
|
270.8 |
|
Day 562 |
599 |
10,000 |
|
224.5 |
|
Day 565 |
470 |
2500 |
|
217.7 |
|
Day 569 |
323 |
0 |
|
180.4 |
|
Day 570 |
581 |
10,000 |
|
362.5 |
|
Day 571 |
329 |
0 |
|
252.3 |
|
Day 578 |
475 |
2500 |
|
221 |
|
Day 583 |
350 |
0 |
|
363.7 |
|
Day 583 |
459 |
2500 |
|
243.7 |
|
Day 585 |
464 |
2500 |
|
235.6 |
|
Day 585 |
572 |
10,000 |
|
195.4 |
|
Day 589 |
472 |
2500 |
|
220.3 |
|
Day 590 |
357 |
625 |
|
253.1 |
|
Day 597 |
309 |
0 |
|
367.5 |
|
Day 597 |
452 |
2500 |
|
263.3 |
|
Day 597 |
494 |
2500 |
|
296.3 |
|
Day 599 |
568 |
10,000 |
|
226.3 |
|
Day 604 |
571 |
10,000 |
|
223.4 |
|
Day 606 |
366 |
625 |
|
236.7 |
|
Day 609 |
562 |
10,000 |
|
315 |
|
Day 609 |
566 |
10,000 |
|
264.5 |
|
Day 611 |
465 |
2500 |
|
220.7 |
|
Day 612 |
356 |
625 |
|
304.1 |
|
Day 613 |
337 |
0 |
|
319.7 |
|
Day 613 |
509 |
5000 |
|
259.2 |
|
Day 624 |
515 |
5000 |
|
213.3 |
|
Day 631 |
375 |
625 |
|
254.2 |
|
Day 631 |
525 |
5000 |
|
354.9 |
|
Day 632 |
493 |
2500 |
|
294.4 |
|
Day 633 |
364 |
625 |
|
204.2 |
|
Day 633 |
499 |
2500 |
|
234.4 |
|
Day 634 |
383 |
625 |
|
325.2 |
|
Day 634 |
497 |
2500 |
|
213.9 |
|
Day 634 |
518 |
5000 |
|
247.9 |
|
Day 638 |
542 |
5000 |
|
183.5 |
|
Day 641 |
308 |
0 |
|
292.5 |
|
Day 641 |
541 |
5000 |
|
229.3 |
|
Day 646 |
481 |
2500 |
|
271.4 |
|
Day 646 |
502 |
5000 |
|
189.2 |
|
Day 646 |
590 |
10,000 |
|
317.8 |
|
Day 647 |
324 |
0 |
|
312.6 |
|
Day 647 |
367 |
625 |
|
327 |
|
Day 652 |
460 |
2500 |
|
337.7 |
|
Day 654 |
382 |
625 |
|
362.8 |
|
Day 662 |
569 |
10,000 |
|
259.9 |
|
Day 666 |
374 |
625 |
|
241.8 |
|
Day 669 |
352 |
625 |
|
182.2 |
|
Day 669 |
492 |
2500 |
|
203.5 |
|
Day 669 |
522 |
5000 |
|
317.2 |
|
Day 669 |
554 |
10,000 |
|
294.8 |
|
Day 669 |
585 |
10,000 |
|
276.6 |
|
Day 675 |
511 |
5000 |
|
193.9 |
|
Day 679 |
548 |
5000 |
|
178.5 |
|
Day 683 |
532 |
5000 |
|
207.6 |
|
Day 690 |
331 |
0 |
|
247.2 |
|
Day 692 |
463 |
2500 |
|
197.2 |
|
Day 696 |
315 |
0 |
|
288.9 |
|
Day 697 |
302 |
0 |
|
309.5 |
|
Day 697 |
363 |
625 |
|
202.7 |
|
Day 697 |
486 |
2500 |
|
198 |
|
Day 697 |
580 |
10,000 |
|
399 |
|
Day 699 |
573 |
10,000 |
|
247.9 |
|
Day 700 |
326 |
0 |
|
265.7 |
|
Day 700 |
455 |
2500 |
|
203 |
|
Day 700 |
482 |
2500 |
|
251.8 |
|
Day 700 |
531 |
5000 |
|
216.5 |
|
Day 701 |
328 |
0 |
|
238.5 |
|
Day 701 |
473 |
2500 |
|
302.2 |
|
Day 703 |
476 |
2500 |
|
261.3 |
|
Day 703 |
498 |
2500 |
|
256.3 |
|
Day 703 |
574 |
10,000 |
|
210.7 |
|
Day 708 |
314 |
0 |
|
259.4 |
|
Day 708 |
387 |
625 |
|
302.7 |
|
Day 711 |
545 |
5000 |
|
206.2 |
|
Day 714 |
575 |
10,000 |
|
304 |
|
Day 715 |
369 |
625 |
|
218.4 |
|
Day 715 |
503 |
5000 |
|
270.3 |
|
Day 715 |
546 |
5000 |
|
245.1 |
|
Day 715 |
594 |
10,000 |
|
418.9 |
|
Day 716 |
587 |
10,000 |
|
276.3 |
|
Day 717 |
355 |
625 |
|
339.1 |
|
Day 718 |
354 |
625 |
|
317.5 |
|
Day 718 |
365 |
625 |
|
242.1 |
|
Day 718 |
370 |
625 |
|
341.8 |
|
Day 718 |
393 |
625 |
|
225.7 |
|
Day 718 |
598 |
10,000 |
|
358.7 |
|
Day 719 |
576 |
10,000 |
|
331.5 |
|
Day 721 |
544 |
5000 |
|
288.8 |
|
Day 725 |
556 |
10,000 |
|
316.9 |
|
Day 725 |
558 |
10,000 |
|
257.1 |
|
Day 728 |
351 |
625 |
|
269.5 |
|
Day 728 |
485 |
2500 |
|
281.3 |
|
Day 729 |
306 |
0 |
|
353.6 |
|
Day 729 |
373 |
625 |
|
317.3 |
|
Day 729 |
376 |
625 |
|
376.5 |
|
Day 729 |
386 |
625 |
|
375.2 |
|
Day 729 |
394 |
625 |
|
378.6 |
|
Day 729 |
397 |
625 |
|
347.8 |
|
Day 729 |
458 |
2500 |
|
225 |
|
Day 729 |
469 |
2500 |
|
300.7 |
|
Day 729 |
483 |
2500 |
|
316 |
|
Day 729 |
495 |
2500 |
|
241.8 |
|
Day 729 |
500 |
2500 |
|
275.7 |
|
Day 729 |
504 |
5000 |
|
278.5 |
|
Day 729 |
505 |
5000 |
|
295.9 |
|
Day 729 |
510 |
5000 |
|
272.7 |
|
Day 729 |
512 |
5000 |
|
237.6 |
|
Day 729 |
517 |
5000 |
|
303.1 |
|
Day 729 |
540 |
5000 |
|
286.9 |
|
Day 729 |
547 |
5000 |
|
289.8 |
|
Day 729 |
551 |
10,000 |
|
336.6 |
|
Day 729 |
577 |
10,000 |
|
339.9 |
|
Day 729 |
591 |
10,000 |
|
375.7 |
|
Day 729 |
595 |
10,000 |
|
343.6 |
|
Day 730 |
303 |
0 |
|
261.3 |
|
Day 730 |
307 |
0 |
|
284.3 |
|
Day 730 |
311 |
0 |
|
339.4 |
|
Day 730 |
312 |
0 |
|
351.7 |
|
Day 730 |
313 |
0 |
|
351.6 |
|
Day 730 |
320 |
0 |
|
372.5 |
|
Day 730 |
321 |
0 |
|
221.3 |
|
Day 730 |
330 |
0 |
|
378 |
|
Day 730 |
333 |
0 |
|
351.4 |
|
Day 730 |
335 |
0 |
|
330 |
|
Day 730 |
336 |
0 |
|
391.5 |
|
Day 730 |
338 |
0 |
|
385.5 |
|
Day 730 |
339 |
0 |
|
365.7 |
|
Day 730 |
343 |
0 |
|
372.1 |
|
Day 730 |
344 |
0 |
|
320.9 |
|
Day 730 |
348 |
0 |
|
344.9 |
|
Day 730 |
353 |
625 |
|
339.2 |
|
Day 730 |
359 |
625 |
|
347 |
|
Day 730 |
361 |
625 |
|
330 |
|
Day 730 |
371 |
625 |
|
347.9 |
|
Day 730 |
372 |
625 |
|
376.4 |
|
Day 730 |
377 |
625 |
|
270.1 |
|
Day 730 |
378 |
625 |
|
354.5 |
|
Day 730 |
379 |
625 |
|
350.6 |
|
Day 730 |
385 |
625 |
|
329 |
|
Day 730 |
396 |
625 |
|
353 |
|
Day 730 |
400 |
625 |
|
345.9 |
|
Day 730 |
451 |
2500 |
|
299.9 |
|
Day 730 |
457 |
2500 |
|
201 |
|
Day 730 |
462 |
2500 |
|
298 |
|
Day 730 |
466 |
2500 |
|
281.2 |
|
Day 730 |
467 |
2500 |
|
307.6 |
|
Day 730 |
474 |
2500 |
|
295.7 |
|
Day 730 |
478 |
2500 |
|
297.7 |
|
Day 730 |
487 |
2500 |
|
294.3 |
|
Day 730 |
491 |
2500 |
|
305.6 |
|
Day 730 |
519 |
5000 |
|
312.4 |
|
Day 730 |
526 |
5000 |
|
274.9 |
|
Day 730 |
527 |
5000 |
|
281.8 |
|
Day 730 |
528 |
5000 |
|
276.2 |
|
Day 730 |
533 |
5000 |
|
274.2 |
|
Day 730 |
534 |
5000 |
|
273.9 |
|
Day 730 |
535 |
5000 |
|
261.3 |
|
Day 730 |
537 |
5000 |
|
287.2 |
|
Day 730 |
539 |
5000 |
|
284.8 |
|
Day 730 |
543 |
5000 |
|
220.8 |
|
Day 730 |
553 |
10,000 |
|
390.6 |
|
Day 730 |
560 |
10,000 |
|
362.2 |
|
Day 730 |
565 |
10,000 |
|
334.3 |
|
Day 730 |
579 |
10,000 |
|
389.4 |
|
Day 730 |
583 |
10,000 |
|
374 |
|
Day 730 |
586 |
10,000 |
|
332.6 |
|
Day 730 |
589 |
10,000 |
|
312.3 |
|
Day 730 |
592 |
10,000 |
|
359.5 |
|
Day 730 |
600 |
10,000 |
|
363.3 |
|
Day 731 |
310 |
0 |
|
359.7 |
|
Day 731 |
316 |
0 |
|
365.9 |
|
Day 731 |
317 |
0 |
|
382.5 |
|
Day 731 |
318 |
0 |
|
382.5 |
|
Day 731 |
319 |
0 |
|
371.5 |
|
Day 731 |
325 |
0 |
|
293.9 |
|
Day 731 |
327 |
0 |
|
351 |
|
Day 731 |
332 |
0 |
|
375.1 |
|
Day 731 |
334 |
0 |
|
328.1 |
|
Day 731 |
340 |
0 |
|
335 |
|
Day 731 |
342 |
0 |
|
321.7 |
|
Day 731 |
345 |
0 |
|
343.9 |
|
Day 731 |
346 |
0 |
|
368 |
|
Day 731 |
347 |
0 |
|
311.1 |
|
Day 731 |
349 |
0 |
|
388.1 |
|
Day 731 |
360 |
625 |
|
308.9 |
|
Day 731 |
362 |
625 |
|
340.5 |
|
Day 731 |
368 |
625 |
|
351 |
|
Day 731 |
388 |
625 |
|
360.6 |
|
Day 731 |
389 |
625 |
|
343.5 |
|
Day 731 |
391 |
625 |
|
329.4 |
|
Day 731 |
392 |
625 |
|
230.3 |
|
Day 731 |
395 |
625 |
|
361.3 |
|
Day 731 |
398 |
625 |
|
275.6 |
|
Day 731 |
399 |
625 |
|
368.7 |
|
Day 731 |
453 |
2500 |
|
326.6 |
|
Day 731 |
454 |
2500 |
|
330.3 |
|
Day 731 |
456 |
2500 |
|
226.3 |
|
Day 731 |
480 |
2500 |
|
328.1 |
|
Day 731 |
490 |
2500 |
|
306.5 |
|
Day 731 |
496 |
2500 |
|
303.5 |
|
Day 731 |
501 |
5000 |
|
249 |
|
Day 731 |
506 |
5000 |
|
264.8 |
|
Day 731 |
507 |
5000 |
|
278.4 |
|
Day 731 |
508 |
5000 |
|
280.9 |
|
Day 731 |
513 |
5000 |
|
258 |
|
Day 731 |
514 |
5000 |
|
274.9 |
|
Day 731 |
516 |
5000 |
|
265.3 |
|
Day 731 |
520 |
5000 |
|
269 |
|
Day 731 |
521 |
5000 |
|
323.3 |
|
Day 731 |
524 |
5000 |
|
268 |
|
Day 731 |
529 |
5000 |
|
297.9 |
|
Day 731 |
530 |
5000 |
|
269.4 |
|
Day 731 |
536 |
5000 |
|
310.7 |
|
Day 731 |
550 |
5000 |
|
283.3 |
|
Day 731 |
552 |
10,000 |
|
392.2 |
|
Day 731 |
555 |
10,000 |
|
362.2 |
|
Day 731 |
557 |
10,000 |
|
344.6 |
|
Day 731 |
559 |
10,000 |
|
313.9 |
|
Day 731 |
561 |
10,000 |
|
332 |
|
Day 731 |
567 |
10,000 |
|
350 |
|
Day 731 |
578 |
10,000 |
|
386.7 |
|
Day 731 |
582 |
10,000 |
|
283.7 |
|
Day 731 |
584 |
10,000 |
|
353.8 |
|
Day 731 |
588 |
10,000 |
|
344.3 |
|
Day 731 |
593 |
10,000 |
|
360.3 |
|
Day 731 |
597 |
10,000 |
|
379.9 |
|
Abbreviations: |
NA: Not Available
|