Alimentary System |
Esophagus |
|
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Hyperkeratosis |
Mild |
Moribund |
Alimentary System |
Esophagus |
|
.1 G/KG |
12 |
15 |
73 |
499 |
1 |
Necrosis |
Moderate |
Moribund |
Alimentary System |
Intestine Large |
Cecum |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Alimentary System |
Intestine Large |
Cecum, Lymphoid Nodul |
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Intestine Large |
Colon |
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Parasite |
Minimal |
Dead |
Alimentary System |
Intestine Large |
Colon |
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Parasite |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Parasite |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Parasite |
Minimal |
Moribund |
Alimentary System |
Intestine Large |
Colon |
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Parasite |
Minimal |
Moribund |
Alimentary System |
Intestine Large |
Colon |
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Parasite |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Parasite |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Parasite |
Minimal |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Parasite |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum |
.1 G/KG |
9 |
11 |
55 |
723 |
1 |
Parasite |
Minimal |
Moribund |
Alimentary System |
Intestine Large |
Rectum |
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Parasite |
Mild |
Terminal Sacrifice |
Alimentary System |
Intestine Small |
Ileum, Lymphoid Nodul |
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Hyperplasia |
Moderate |
Gavage Death |
Alimentary System |
Intestine Small |
Ileum, Lymphoid Tiss |
.1 G/KG |
9 |
13 |
64 |
631 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Intestine Small |
Jejunum |
.1 G/KG |
9 |
16 |
79 |
517 |
1 |
Hemorrhage |
Mild |
Moribund |
Alimentary System |
Intestine Small |
Jejunum |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Alimentary System |
Liver |
Artery |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Hyperplasia |
Mild |
Dead |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
1 |
5 |
707 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
1 |
4 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
2 |
10 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
2 |
7 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
3 |
11 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
5 |
23 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
5 |
24 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
7 |
34 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
8 |
40 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
9 |
42 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
9 |
43 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
Vehicle Control |
50 |
9 |
45 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
11 |
54 |
664 |
1 |
Hyperplasia |
Mild |
Dead |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
17 |
85 |
503 |
1 |
Hyperplasia |
Mild |
Dead |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
15 |
73 |
499 |
1 |
Hyperplasia |
Minimal |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
16 |
79 |
517 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
18 |
87 |
462 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
18 |
89 |
582 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
11 |
52 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
11 |
53 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
12 |
58 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
12 |
59 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
13 |
61 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
13 |
62 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
14 |
66 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
15 |
72 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
15 |
74 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
15 |
75 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
16 |
76 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
16 |
77 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
16 |
80 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
17 |
82 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
17 |
83 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
17 |
84 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
18 |
88 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
19 |
94 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.1 G/KG |
41 |
20 |
99 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
23 |
113 |
666 |
1 |
Hyperplasia |
Mild |
Dead |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Hyperplasia |
Mild |
Dead |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Hyperplasia |
Mild |
Dead |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Hyperplasia |
Mild |
Gavage Death |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
23 |
114 |
491 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
30 |
146 |
580 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
26 |
127 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
28 |
138 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Bile Duct |
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
4 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
10 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
11 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
4 |
16 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
5 |
23 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
5 |
24 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
7 |
34 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
42 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
43 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
45 |
738 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
11 |
54 |
664 |
1 |
Basophilic Focus |
|
Dead |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
16 |
78 |
651 |
1 |
Basophilic Focus |
|
Gavage Death |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
11 |
51 |
667 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
68 |
730 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
69 |
616 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
15 |
73 |
499 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
16 |
79 |
517 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
18 |
89 |
582 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
20 |
98 |
730 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
11 |
52 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
11 |
53 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
12 |
58 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
12 |
59 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
13 |
61 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
13 |
62 |
736 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
66 |
736 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
67 |
736 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
70 |
736 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
15 |
72 |
736 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
15 |
75 |
736 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
16 |
76 |
736 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
17 |
81 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
17 |
82 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
17 |
83 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
19 |
94 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
20 |
100 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
20 |
99 |
737 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Basophilic Focus |
|
Dead |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Basophilic Focus |
|
Dead |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
23 |
112 |
600 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
120 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
26 |
127 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
26 |
129 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
28 |
138 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Clear Cell Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
11 |
53 |
735 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
13 |
62 |
736 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
67 |
736 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
70 |
736 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
15 |
72 |
736 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
16 |
80 |
737 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
17 |
82 |
737 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
17 |
83 |
737 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
19 |
94 |
737 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
20 |
100 |
737 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
20 |
99 |
737 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Congestion |
Mild |
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
68 |
730 |
1 |
Congestion |
Moderate |
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
66 |
736 |
1 |
Cyst |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
68 |
730 |
1 |
Degeneration |
Minimal |
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
15 |
72 |
736 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Eosinophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Fatty Change |
Minimal, Focal |
Dead |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
6 |
28 |
737 |
1 |
Fatty Change |
Minimal, Focal |
Dead |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Fatty Change |
Mild, Focal |
Dead |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Fatty Change |
Mild, Diffuse |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
50 |
671 |
1 |
Fatty Change |
Mild, Diffuse |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Fatty Change |
Moderate, Diffuse |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Fatty Change |
Moderate, Diffuse |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Fatty Change |
Mild, Focal |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Fatty Change |
Mild, Diffuse |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
4 |
737 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
10 |
737 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
7 |
737 |
1 |
Fatty Change |
Mild, Diffuse |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Fatty Change |
Minimal, Diffuse |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
5 |
23 |
738 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
7 |
34 |
738 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
8 |
40 |
740 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
43 |
738 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
45 |
738 |
1 |
Fatty Change |
Minimal, Diffuse |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
17 |
85 |
503 |
1 |
Fatty Change |
Mild, Diffuse |
Dead |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
16 |
78 |
651 |
1 |
Fatty Change |
Mild, Diffuse |
Gavage Death |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
68 |
730 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
69 |
616 |
1 |
Fatty Change |
Mild, Diffuse |
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
15 |
73 |
499 |
1 |
Fatty Change |
Mild, Focal |
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
16 |
79 |
517 |
1 |
Fatty Change |
Mild, Diffuse |
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
18 |
87 |
462 |
1 |
Fatty Change |
Mild, Focal |
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
18 |
89 |
582 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
11 |
52 |
735 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
11 |
53 |
735 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
12 |
58 |
735 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
13 |
61 |
735 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
13 |
62 |
736 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
13 |
63 |
735 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
14 |
70 |
736 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
16 |
76 |
736 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
17 |
81 |
737 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
20 |
99 |
737 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Fatty Change |
Mild, Focal |
Dead |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Fatty Change |
Minimal, Focal |
Dead |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Fatty Change |
Mild, Diffuse |
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Fatty Change |
Mild, Focal |
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
29 |
142 |
372 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Fatty Change |
Minimal, Focal |
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Fatty Change |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Fatty Change |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Focal Cellular Change |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Focal Cellular Change |
|
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
50 |
671 |
1 |
Hepatodiaphragmatic Nodule |
|
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Hepatodiaphragmatic Nodule |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Hepatodiaphragmatic Nodule |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
12 |
57 |
292 |
1 |
Hepatodiaphragmatic Nodule |
|
Dead |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
18 |
89 |
582 |
1 |
Hepatodiaphragmatic Nodule |
|
Moribund |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
13 |
61 |
735 |
1 |
Hepatodiaphragmatic Nodule |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
13 |
62 |
736 |
1 |
Hepatodiaphragmatic Nodule |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
16 |
76 |
736 |
1 |
Hepatodiaphragmatic Nodule |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
17 |
84 |
737 |
1 |
Hepatodiaphragmatic Nodule |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Hepatodiaphragmatic Nodule |
|
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Hepatodiaphragmatic Nodule |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Hepatodiaphragmatic Nodule |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
5 |
707 |
1 |
Mixed Cell Focus |
|
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Mixed Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
16 |
78 |
651 |
1 |
Mixed Cell Focus |
|
Gavage Death |
Alimentary System |
Liver |
|
.1 G/KG |
41 |
13 |
62 |
736 |
1 |
Mixed Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Mixed Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Necrosis |
Mild |
Dead |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Necrosis |
Mild |
Moribund |
Alimentary System |
Liver |
|
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Necrosis |
Minimal |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
5 |
24 |
738 |
1 |
Regeneration |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Mesentery |
Artery |
Vehicle Control |
9 |
4 |
18 |
293 |
1 |
Necrosis |
Moderate, Fibrinoid |
Moribund |
Alimentary System |
Mesentery |
Artery |
Vehicle Control |
9 |
3 |
14 |
737 |
1 |
Necrosis |
Moderate, Fibrinoid |
Terminal Sacrifice |
Alimentary System |
Mesentery |
Fat |
.4 G/KG |
5 |
25 |
122 |
713 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Alimentary System |
Mesentery |
Fat |
.4 G/KG |
5 |
23 |
111 |
730 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Mesentery |
Fat |
Vehicle Control |
9 |
3 |
15 |
636 |
1 |
Necrosis |
Marked |
Moribund |
Alimentary System |
Mesentery |
Fat |
Vehicle Control |
9 |
4 |
16 |
738 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Alimentary System |
Mesentery |
Fat |
Vehicle Control |
9 |
5 |
22 |
738 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Alimentary System |
Mesentery |
Fat |
Vehicle Control |
9 |
6 |
30 |
737 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Alimentary System |
Mesentery |
Fat |
.1 G/KG |
4 |
19 |
93 |
699 |
1 |
Necrosis |
Moderate |
Moribund |
Alimentary System |
Mesentery |
Fat |
.4 G/KG |
5 |
21 |
101 |
730 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Alimentary System |
Mesentery |
Fat |
.4 G/KG |
5 |
23 |
111 |
730 |
1 |
Pigmentation |
Moderate |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
.1 G/KG |
20 |
12 |
57 |
292 |
1 |
Atrophy |
Mild |
Dead |
Alimentary System |
Pancreas |
Acinus |
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Atrophy |
Mild |
Moribund |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Hyperplasia |
Moderate |
Moribund |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
7 |
34 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
.1 G/KG |
20 |
17 |
85 |
503 |
1 |
Hyperplasia |
Moderate |
Dead |
Alimentary System |
Pancreas |
Acinus |
.1 G/KG |
20 |
15 |
72 |
736 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Pancreas |
Acinus |
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
.4 G/KG |
50 |
26 |
127 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
.4 G/KG |
50 |
26 |
129 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Artery |
.1 G/KG |
20 |
14 |
70 |
736 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Artery |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Necrosis |
Moderate, Fibrinoid |
Moribund |
Alimentary System |
Pancreas |
Artery |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Necrosis |
Minimal, Fibrinoid |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Artery |
.1 G/KG |
20 |
13 |
65 |
736 |
1 |
Necrosis |
Moderate, Fibrinoid |
Terminal Sacrifice |
Alimentary System |
Pharynx |
|
.1 G/KG |
1 |
11 |
55 |
723 |
1 |
Hyperplasia, Pseudoepithel |
Moderate, Pseudoepithel |
Moribund |
Alimentary System |
Salivary Glands |
Acinus |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Artery |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Necrosis |
Mild, Fibrinoid |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.1 G/KG |
16 |
13 |
65 |
736 |
1 |
Inflammation |
Minimal, Acute |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
2 |
8 |
737 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Metaplasia |
Mild, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Metaplasia |
Mild, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.1 G/KG |
16 |
13 |
64 |
631 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
.1 G/KG |
16 |
20 |
98 |
730 |
1 |
Metaplasia |
Mild |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
.1 G/KG |
16 |
12 |
59 |
735 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.1 G/KG |
16 |
13 |
65 |
736 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.1 G/KG |
16 |
14 |
67 |
736 |
1 |
Metaplasia |
Mild, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.1 G/KG |
16 |
17 |
81 |
737 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
23 |
112 |
600 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Metaplasia |
Mild, Squamous |
Moribund |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Metaplasia |
Mild, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Metaplasia |
Minimal, Squamous |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Duct |
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Metaplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
|
.1 G/KG |
16 |
14 |
67 |
736 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
|
.1 G/KG |
16 |
13 |
62 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Artery, Forestomach |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Necrosis |
Moderate, Fibrinoid |
Moribund |
Alimentary System |
Stomach |
Artery, Glandular |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Necrosis |
Moderate, Fibrinoid |
Moribund |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Acanthosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Acanthosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
15 |
73 |
499 |
1 |
Acanthosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
19 |
92 |
694 |
1 |
Acanthosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
19 |
93 |
699 |
1 |
Acanthosis |
Moderate |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Acanthosis |
Mild |
Dead |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Acanthosis |
Moderate |
Dead |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Acanthosis |
Minimal |
Dead |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Acanthosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Acanthosis |
Minimal |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Acanthosis |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Hyperkeratosis |
Moderate |
Moribund |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Hyperkeratosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Hyperkeratosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
12 |
57 |
292 |
1 |
Hyperkeratosis |
Mild |
Dead |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
15 |
73 |
499 |
1 |
Hyperkeratosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
19 |
92 |
694 |
1 |
Hyperkeratosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Hyperkeratosis |
Mild |
Dead |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Hyperkeratosis |
Moderate |
Dead |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Hyperkeratosis |
Minimal |
Dead |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Hyperkeratosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Hyperkeratosis |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
17 |
85 |
503 |
1 |
Hyperplasia, Basal Cell |
Minimal, Basal Cell |
Dead |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
19 |
93 |
699 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
19 |
93 |
699 |
1 |
Mineralization |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Necrosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Necrosis |
Moderate |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.1 G/KG |
12 |
19 |
92 |
694 |
1 |
Necrosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Necrosis |
Minimal |
Moribund |
Alimentary System |
Stomach |
Forestomach |
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Necrosis |
Mild |
Moribund |
Alimentary System |
Stomach |
Glandular |
.4 G/KG |
50 |
23 |
114 |
491 |
1 |
Hyperplasia |
Mild |
Moribund |
Alimentary System |
Stomach |
Glandular |
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Mineralization |
Mild |
Moribund |
Alimentary System |
Stomach |
Glandular |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Necrosis |
Minimal |
Moribund |
Cardiovascular System |
Blood Vessel |
Artery |
Vehicle Control |
1 |
4 |
18 |
293 |
1 |
Necrosis |
Minimal, Fibrinoid |
Moribund |
Cardiovascular System |
Heart |
Artery |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Necrosis |
Mild, Fibrinoid |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
6 |
28 |
737 |
1 |
Cardiomyopathy |
Mild |
Dead |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
9 |
44 |
658 |
1 |
Cardiomyopathy |
Mild |
Dead |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
5 |
707 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
50 |
671 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Cardiomyopathy |
Moderate |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Cardiomyopathy |
Minimal |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
4 |
737 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
2 |
10 |
737 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
2 |
7 |
737 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
3 |
11 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
5 |
23 |
738 |
1 |
Cardiomyopathy |
Minimal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
34 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Cardiomyopathy |
Moderate |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
9 |
42 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
9 |
43 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
9 |
45 |
738 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.1 G/KG |
8 |
12 |
57 |
292 |
1 |
Cardiomyopathy |
Mild |
Dead |
Cardiovascular System |
Heart |
|
.1 G/KG |
8 |
17 |
85 |
503 |
1 |
Cardiomyopathy |
Mild |
Dead |
Cardiovascular System |
Heart |
|
.1 G/KG |
8 |
13 |
64 |
631 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.1 G/KG |
8 |
14 |
69 |
616 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.1 G/KG |
8 |
15 |
73 |
499 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.1 G/KG |
8 |
16 |
79 |
517 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.1 G/KG |
8 |
18 |
87 |
462 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.1 G/KG |
8 |
18 |
89 |
582 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
23 |
113 |
666 |
1 |
Cardiomyopathy |
Moderate |
Dead |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
27 |
131 |
690 |
1 |
Cardiomyopathy |
Mild |
Dead |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Cardiomyopathy |
Mild |
Dead |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Cardiomyopathy |
Mild |
Dead |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Cardiomyopathy |
Mild |
Dead |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Cardiomyopathy |
Mild |
Gavage Death |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
23 |
112 |
600 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
23 |
114 |
491 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Cardiomyopathy |
Moderate |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
26 |
130 |
574 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
29 |
142 |
372 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
30 |
146 |
580 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Cardiomyopathy |
Mild |
Moribund |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Cardiomyopathy |
Moderate |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
24 |
120 |
735 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
28 |
138 |
735 |
1 |
Cardiomyopathy |
Mild |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Cardiomyopathy |
Minimal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Cardiomyopathy |
Moderate |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Cardiomyopathy |
Moderate |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Thrombosis |
|
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Hemorrhage |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
.1 G/KG |
50 |
14 |
68 |
730 |
1 |
Hemorrhage |
Moderate |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
.1 G/KG |
50 |
11 |
52 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
.1 G/KG |
50 |
13 |
65 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
.1 G/KG |
50 |
16 |
77 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Vacuolization Cytoplasmic |
Moderate |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
9 |
42 |
738 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
9 |
45 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
17 |
85 |
503 |
1 |
Hyperplasia |
Mild |
Dead |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
18 |
87 |
462 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
19 |
93 |
699 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
20 |
98 |
730 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
11 |
52 |
735 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
11 |
53 |
735 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
12 |
56 |
735 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
12 |
59 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
13 |
61 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
14 |
66 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
14 |
67 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
17 |
81 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
17 |
83 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
18 |
90 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.1 G/KG |
50 |
20 |
99 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
30 |
146 |
580 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
26 |
129 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
|
.1 G/KG |
50 |
15 |
75 |
736 |
1 |
Accessory Adrenal Cortical Nodule |
|
Terminal Sacrifice |
Endocrine System |
Islets |
Pancreatic |
Vehicle Control |
50 |
3 |
11 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Islets |
Pancreatic |
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Islets |
Pancreatic |
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Islets |
Pancreatic |
Vehicle Control |
50 |
9 |
43 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Islets |
Pancreatic |
.1 G/KG |
19 |
19 |
92 |
694 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Islets |
Pancreatic |
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Parathyroid Gland |
|
Vehicle Control |
50 |
8 |
40 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Angiectasis |
Mild |
Dead |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Angiectasis |
Moderate |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Angiectasis |
Moderate |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
2 |
8 |
737 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
4 |
16 |
738 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
15 |
71 |
650 |
1 |
Angiectasis |
Marked |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
12 |
56 |
735 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
12 |
59 |
735 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
12 |
60 |
735 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
14 |
66 |
736 |
1 |
Angiectasis |
Moderate |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
14 |
67 |
736 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
16 |
80 |
737 |
1 |
Angiectasis |
Moderate |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
17 |
81 |
737 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
19 |
95 |
737 |
1 |
Angiectasis |
Moderate |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
20 |
100 |
737 |
1 |
Angiectasis |
Moderate |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
20 |
99 |
737 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Angiectasis |
Moderate |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Angiectasis |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
26 |
130 |
574 |
1 |
Angiectasis |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Angiectasis |
Marked |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Angiectasis |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Angiectasis |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
13 |
64 |
631 |
1 |
Cyst |
|
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Hemorrhage |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Hemorrhage |
Marked |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
9 |
44 |
658 |
1 |
Hyperplasia |
Mild |
Dead |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
3 |
11 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
11 |
54 |
664 |
1 |
Hyperplasia |
Mild |
Dead |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
19 |
93 |
699 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
11 |
53 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
12 |
60 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
19 |
94 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
20 |
99 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
23 |
113 |
666 |
1 |
Hyperplasia |
Mild |
Dead |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
26 |
129 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Necrosis |
Moderate |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
.1 G/KG |
26 |
12 |
56 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Intermed |
.1 G/KG |
26 |
18 |
87 |
462 |
1 |
Angiectasis |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Intermed |
.1 G/KG |
26 |
14 |
67 |
736 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Intermed |
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
2 |
8 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
8 |
40 |
740 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
.1 G/KG |
12 |
18 |
89 |
582 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Hyperplasia |
Minimal |
Dead |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Hyperplasia |
Mild |
Dead |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
26 |
127 |
735 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
26 |
129 |
735 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
28 |
138 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
Capsule |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Necrosis |
Mild, Fibrinoid |
Moribund |
Endocrine System |
Thyroid Gland |
|
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Hemorrhage |
Mild |
Dead |
Genital System |
Epididymis |
|
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Fibrosis |
Mild |
Moribund |
Genital System |
Epididymis |
|
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Epididymis |
|
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Epididymis |
|
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Spermatocele |
Mild |
Moribund |
Genital System |
Epididymis |
|
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Spermatocele |
|
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Cyst |
|
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
.1 G/KG |
15 |
12 |
60 |
735 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Necrosis |
Moderate |
Dead |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Necrosis |
Mild |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Necrosis |
Moderate |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
.4 G/KG |
50 |
23 |
113 |
666 |
1 |
Necrosis |
Moderate |
Dead |
Genital System |
Preputial Gland |
|
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Necrosis |
Mild |
Moribund |
Genital System |
Preputial Gland |
|
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Necrosis |
Moderate |
Moribund |
Genital System |
Preputial Gland |
|
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Necrosis |
Moderate |
Moribund |
Genital System |
Preputial Gland |
|
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Genital System |
Prostate |
Artery |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Necrosis |
Mild, Fibrinoid |
Moribund |
Genital System |
Prostate |
Epithelium |
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Prostate |
Epithelium |
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Prostate |
Epithelium |
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Prostate |
Epithelium |
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Prostate |
Epithelium |
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
1 |
5 |
707 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
.1 G/KG |
10 |
12 |
57 |
292 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Prostate |
|
.1 G/KG |
10 |
19 |
93 |
699 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Prostate |
|
.4 G/KG |
50 |
23 |
112 |
600 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Seminal Vesicle |
|
.1 G/KG |
30 |
12 |
57 |
292 |
1 |
Concretion |
Mild |
Dead |
Genital System |
Seminal Vesicle |
|
.1 G/KG |
30 |
18 |
89 |
582 |
1 |
Concretion |
Mild |
Moribund |
Genital System |
Seminal Vesicle |
|
.1 G/KG |
30 |
19 |
91 |
737 |
1 |
Concretion |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
5 |
23 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
9 |
45 |
738 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
17 |
85 |
503 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
11 |
55 |
723 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
13 |
64 |
631 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
15 |
71 |
650 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
15 |
73 |
499 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
16 |
79 |
517 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
18 |
89 |
582 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
20 |
98 |
730 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
11 |
53 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
12 |
58 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
12 |
59 |
735 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
14 |
66 |
736 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
14 |
67 |
736 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
16 |
76 |
736 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
17 |
81 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
17 |
82 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
17 |
83 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
17 |
84 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
20 |
96 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.1 G/KG |
44 |
20 |
99 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
23 |
112 |
600 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
23 |
114 |
491 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
28 |
136 |
336 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
29 |
142 |
372 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
30 |
146 |
580 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
26 |
129 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Atrophy |
Marked |
Dead |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Atrophy |
Mild |
Dead |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
10 |
50 |
671 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
1 |
4 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
2 |
10 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
2 |
8 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
3 |
11 |
738 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
4 |
16 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
5 |
23 |
738 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
5 |
24 |
738 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
8 |
40 |
740 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
9 |
42 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
9 |
43 |
738 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
11 |
54 |
664 |
1 |
Atrophy |
Moderate |
Dead |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
20 |
97 |
672 |
1 |
Atrophy |
Moderate |
Dead |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
14 |
68 |
730 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
15 |
71 |
650 |
1 |
Atrophy |
Moderate |
Moribund |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
20 |
98 |
730 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
11 |
53 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
12 |
58 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
12 |
59 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
13 |
61 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
13 |
63 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
14 |
66 |
736 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
14 |
67 |
736 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
15 |
74 |
736 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
15 |
75 |
736 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
16 |
76 |
736 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
16 |
77 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
17 |
81 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
17 |
82 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
17 |
83 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
18 |
86 |
737 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
18 |
90 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
19 |
94 |
737 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
19 |
95 |
737 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
20 |
96 |
737 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.1 G/KG |
44 |
20 |
99 |
737 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
23 |
113 |
666 |
1 |
Atrophy |
Mild |
Dead |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Atrophy |
Mild |
Dead |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Atrophy |
Mild |
Dead |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Atrophy |
Moderate |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Atrophy |
Moderate |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Atrophy |
Moderate |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
26 |
127 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
26 |
129 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
|
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
|
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Congestion |
Minimal |
Moribund |
Hematopoietic System |
Lymph Node |
Iliac |
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Lumbar |
.1 G/KG |
27 |
13 |
62 |
736 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Lumbar |
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Lumbar |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Hemorrhage |
Mild |
Dead |
Hematopoietic System |
Lymph Node |
Lumbar |
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Hemorrhage |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Lumbar |
.1 G/KG |
27 |
20 |
97 |
672 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Dead |
Hematopoietic System |
Lymph Node |
Lumbar |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Dead |
Hematopoietic System |
Lymph Node |
Lumbar |
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Lumbar |
.1 G/KG |
27 |
20 |
97 |
672 |
1 |
Pigmentation |
Mild |
Dead |
Hematopoietic System |
Lymph Node |
Mandibular |
.1 G/KG |
27 |
13 |
65 |
736 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Necrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Angiectasis |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
.1 G/KG |
27 |
17 |
81 |
737 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Angiectasis |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Angiectasis |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Angiectasis |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Depletion Lymphoid |
Mild |
Dead |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
50 |
1 |
5 |
707 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
.1 G/KG |
27 |
14 |
69 |
616 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
.1 G/KG |
27 |
12 |
60 |
735 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
.1 G/KG |
27 |
11 |
51 |
667 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
.1 G/KG |
27 |
11 |
55 |
723 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
.1 G/KG |
27 |
12 |
60 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
.1 G/KG |
27 |
18 |
90 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
11 |
54 |
664 |
1 |
Angiectasis |
Moderate |
Dead |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
16 |
77 |
737 |
1 |
Angiectasis |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Angiectasis |
Moderate |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Angiectasis |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Angiectasis |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Depletion Lymphoid |
Mild |
Dead |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Depletion Lymphoid |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Hemorrhage |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
20 |
98 |
730 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
12 |
60 |
735 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
15 |
72 |
736 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
20 |
100 |
737 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
23 |
113 |
666 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Dead |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Dead |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Gavage Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Infiltration Cellular |
Mild, Mast Cell |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Infiltration Cellular |
Minimal, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
24 |
120 |
735 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Infiltration Cellular |
Minimal, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
26 |
127 |
735 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
11 |
51 |
667 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
11 |
55 |
723 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
19 |
93 |
699 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
20 |
98 |
730 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
12 |
60 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
13 |
61 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
14 |
66 |
736 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
18 |
86 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
.1 G/KG |
27 |
20 |
100 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric, Renal |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Angiectasis |
Moderate |
Moribund |
Hematopoietic System |
Lymph Node |
Pancreatic |
.1 G/KG |
27 |
12 |
59 |
735 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
.1 G/KG |
27 |
19 |
95 |
737 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Pancreatic |
.1 G/KG |
27 |
11 |
51 |
667 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Pancreatic |
.1 G/KG |
27 |
11 |
55 |
723 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Pancreatic |
.1 G/KG |
27 |
12 |
59 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
.1 G/KG |
27 |
14 |
66 |
736 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
.1 G/KG |
27 |
15 |
72 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
.1 G/KG |
27 |
19 |
95 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Angiectasis |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Angiectasis |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.1 G/KG |
27 |
13 |
62 |
736 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Angiectasis |
Moderate |
Dead |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Angiectasis |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Depletion Lymphoid |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Hemorrhage |
Minimal |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
Vehicle Control |
50 |
1 |
5 |
707 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
Vehicle Control |
50 |
10 |
50 |
671 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
.1 G/KG |
27 |
20 |
98 |
730 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.1 G/KG |
27 |
15 |
72 |
736 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Dead |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Infiltration Cellular |
Minimal, Histiocyte |
Dead |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
.1 G/KG |
27 |
11 |
51 |
667 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.1 G/KG |
27 |
19 |
93 |
699 |
1 |
Pigmentation |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
.1 G/KG |
27 |
13 |
65 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Renal |
.1 G/KG |
27 |
15 |
72 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Capsule |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Fibrosis |
Mild |
Moribund |
Hematopoietic System |
Spleen |
Capsule |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
20 |
99 |
737 |
1 |
Congestion |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Depletion Lymphoid |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
12 |
57 |
292 |
1 |
Depletion Lymphoid |
Mild |
Dead |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Depletion Lymphoid |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Depletion Lymphoid |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
16 |
77 |
737 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Dead |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
10 |
50 |
671 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
1 |
4 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
7 |
34 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
8 |
40 |
740 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
9 |
43 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
9 |
45 |
738 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
13 |
64 |
631 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
14 |
69 |
616 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
16 |
79 |
517 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
14 |
70 |
736 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
17 |
84 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
18 |
86 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
18 |
88 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
19 |
91 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
20 |
99 |
737 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Dead |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Dead |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Gavage Death |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
23 |
112 |
600 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
26 |
130 |
574 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
29 |
142 |
372 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
30 |
146 |
580 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
24 |
120 |
735 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
28 |
138 |
735 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
16 |
77 |
737 |
1 |
Hemorrhage |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Hemorrhage |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Moribund |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
28 |
136 |
336 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
6 |
28 |
737 |
1 |
Necrosis |
Mild |
Dead |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Necrosis |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
.1 G/KG |
19 |
20 |
97 |
672 |
1 |
Necrosis |
Moderate |
Dead |
Hematopoietic System |
Spleen |
|
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
Epithel Cell |
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
Epithel Cell |
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
Epithel Cell |
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Atrophy |
Moderate |
Moribund |
Hematopoietic System |
Thymus |
|
.4 G/KG |
50 |
28 |
136 |
336 |
1 |
Atrophy |
Moderate |
Moribund |
Hematopoietic System |
Thymus |
|
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Depletion Lymphoid |
Marked |
Dead |
Integumentary System |
Mammary Gland |
Acinus |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Hyperplasia |
Moderate |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Galactocele |
|
Dead |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
50 |
1 |
5 |
707 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
50 |
4 |
16 |
738 |
1 |
Galactocele |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Galactocele |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
.1 G/KG |
13 |
18 |
87 |
462 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
.1 G/KG |
13 |
19 |
93 |
699 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
.1 G/KG |
13 |
14 |
66 |
736 |
1 |
Galactocele |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
.4 G/KG |
50 |
26 |
130 |
574 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Galactocele |
|
Moribund |
Integumentary System |
Mammary Gland |
|
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Galactocele |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Abscess |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Cyst Epithelial Inclusion |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Cyst Epithelial Inclusion |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
.1 G/KG |
20 |
18 |
88 |
737 |
1 |
Cyst Epithelial Inclusion |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Cyst Epithelial Inclusion |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Hyperkeratosis |
Moderate |
Moribund |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Hyperkeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Hyperkeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Hyperkeratosis |
Marked |
Terminal Sacrifice |
Integumentary System |
Skin |
|
.1 G/KG |
20 |
19 |
92 |
694 |
1 |
Hyperkeratosis |
Moderate |
Moribund |
Integumentary System |
Skin |
|
.1 G/KG |
20 |
16 |
77 |
737 |
1 |
Hyperkeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
|
.1 G/KG |
20 |
18 |
88 |
737 |
1 |
Hyperkeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Hyperkeratosis |
Moderate |
Moribund |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Hyperkeratosis |
Marked |
Moribund |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Hyperkeratosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Hyperkeratosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
|
.1 G/KG |
20 |
18 |
88 |
737 |
1 |
Hyperplasia, Basal Cell |
Minimal, Basal Cell |
Terminal Sacrifice |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Hyperplasia, Basal Cell |
Minimal, Basal Cell |
Terminal Sacrifice |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Inflammation |
Marked, Acute |
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Necrosis |
Moderate |
Dead |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
23 |
112 |
600 |
1 |
Necrosis |
Mild |
Moribund |
Integumentary System |
Skin |
|
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Integumentary System |
Skin |
|
.1 G/KG |
20 |
18 |
86 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Nervous System |
Brain |
Artery |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Necrosis |
Mild, Fibrinoid |
Moribund |
Nervous System |
Brain |
Brain Stem |
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Nervous System |
Brain |
Cerebellum |
.1 G/KG |
8 |
15 |
73 |
499 |
1 |
Hemorrhage |
Mild |
Moribund |
Nervous System |
Brain |
Cerebellum |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Nervous System |
Brain |
Cerebellum |
.1 G/KG |
8 |
15 |
73 |
499 |
1 |
Necrosis |
Mild |
Moribund |
Nervous System |
Brain |
Cerebrum |
.1 G/KG |
8 |
17 |
85 |
503 |
1 |
Hemorrhage |
Moderate |
Dead |
Nervous System |
Brain |
Cerebrum |
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Hemorrhage |
Minimal |
Moribund |
Respiratory System |
Lung |
Alveolar Epith |
Vehicle Control |
50 |
5 |
23 |
738 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
.1 G/KG |
18 |
18 |
87 |
462 |
1 |
Hyperplasia |
Mild |
Moribund |
Respiratory System |
Lung |
Alveolar Epith |
.1 G/KG |
18 |
12 |
60 |
735 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
.1 G/KG |
18 |
17 |
83 |
737 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Hyperplasia |
Minimal |
Moribund |
Respiratory System |
Lung |
Alveolar Epith |
.4 G/KG |
50 |
24 |
120 |
735 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Respiratory System |
Lung |
Artery |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Necrosis |
Moderate, Fibrinoid |
Moribund |
Respiratory System |
Lung |
Bronchiole |
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Metaplasia |
Minimal, Squamous |
Moribund |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Atelectasis |
Mild |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Bronchiectasis |
Mild |
Moribund |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Congestion |
Mild |
Dead |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Congestion |
Mild |
Moribund |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Congestion |
Mild |
Moribund |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
11 |
54 |
664 |
1 |
Congestion |
Mild |
Dead |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
16 |
78 |
651 |
1 |
Congestion |
Marked |
Gavage Death |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
14 |
68 |
730 |
1 |
Congestion |
Minimal |
Moribund |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
12 |
56 |
735 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Congestion |
Mild |
Moribund |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Congestion |
Mild |
Moribund |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Congestion |
Mild |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Edema |
Minimal |
Dead |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
11 |
54 |
664 |
1 |
Edema |
Minimal |
Dead |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
12 |
57 |
292 |
1 |
Edema |
Mild |
Dead |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Edema |
Mild |
Dead |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Edema |
Mild |
Gavage Death |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Edema |
Mild |
Moribund |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
16 |
78 |
651 |
1 |
Hemorrhage |
Mild |
Gavage Death |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
17 |
83 |
737 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
18 |
88 |
737 |
1 |
Hemorrhage |
Mild |
Terminal Sacrifice |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Hemorrhage |
Minimal |
Dead |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Hemorrhage |
Minimal |
Dead |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Hemorrhage |
Mild |
Gavage Death |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Hemorrhage |
Minimal |
Moribund |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Hemorrhage |
Minimal |
Moribund |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
28 |
138 |
735 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Dead |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Terminal Sacrifice |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Infiltration Cellular |
Mild, Histiocyte |
Moribund |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
26 |
130 |
574 |
1 |
Infiltration Cellular |
Minimal, Histiocyte |
Moribund |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
29 |
142 |
372 |
1 |
Infiltration Cellular |
Minimal, Histiocyte |
Moribund |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Infiltration Cellular |
Minimal, Histiocyte |
Terminal Sacrifice |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
26 |
127 |
735 |
1 |
Infiltration Cellular |
Minimal, Histiocyte |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Lung |
|
.1 G/KG |
18 |
18 |
88 |
737 |
1 |
Inflammation |
Moderate, Acute |
Terminal Sacrifice |
Respiratory System |
Lung |
|
.4 G/KG |
50 |
28 |
136 |
336 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Respiratory System |
Nose |
|
.1 G/KG |
9 |
16 |
78 |
651 |
1 |
Congestion |
Mild |
Gavage Death |
Respiratory System |
Nose |
|
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Nose |
|
.1 G/KG |
9 |
15 |
73 |
499 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Respiratory System |
Nose |
|
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Respiratory System |
Nose |
|
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Respiratory System |
Nose |
|
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Nose |
|
.4 G/KG |
50 |
24 |
120 |
735 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Nose |
|
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Nose |
|
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Nose |
|
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Trachea |
|
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Erosion |
Moderate |
Gavage Death |
Special Senses System |
Ear |
|
.4 G/KG |
3 |
21 |
104 |
588 |
1 |
Hemorrhage |
Mild |
Moribund |
Special Senses System |
Ear |
|
.4 G/KG |
3 |
21 |
104 |
588 |
1 |
Necrosis |
Moderate |
Moribund |
Special Senses System |
Eye |
Lens |
Vehicle Control |
5 |
10 |
49 |
730 |
1 |
Cataract |
Moderate |
Moribund |
Special Senses System |
Eye |
Lens |
.1 G/KG |
8 |
13 |
64 |
631 |
1 |
Cataract |
Mild |
Moribund |
Special Senses System |
Eye |
Lens |
.1 G/KG |
8 |
19 |
93 |
699 |
1 |
Cataract |
Moderate |
Moribund |
Special Senses System |
Eye |
Lens |
.1 G/KG |
8 |
18 |
90 |
737 |
1 |
Cataract |
Mild |
Terminal Sacrifice |
Special Senses System |
Eye |
Lens |
.4 G/KG |
11 |
25 |
121 |
704 |
1 |
Cataract |
Mild |
Moribund |
Special Senses System |
Eye |
Lens |
.4 G/KG |
11 |
25 |
124 |
704 |
1 |
Cataract |
Mild |
Moribund |
Special Senses System |
Eye |
Lens |
.4 G/KG |
11 |
30 |
150 |
562 |
1 |
Cataract |
Mild |
Moribund |
Special Senses System |
Eye |
Retina |
.4 G/KG |
11 |
22 |
110 |
611 |
1 |
Atrophy |
Moderate |
Moribund |
Special Senses System |
Eye |
Retina |
.4 G/KG |
11 |
25 |
121 |
704 |
1 |
Atrophy |
Mild |
Moribund |
Special Senses System |
Eye |
Retina |
.4 G/KG |
11 |
22 |
106 |
730 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Special Senses System |
Eye |
Retina |
Vehicle Control |
5 |
10 |
49 |
730 |
1 |
Hemorrhage |
Moderate |
Moribund |
Special Senses System |
Eye |
Sclera |
.4 G/KG |
11 |
22 |
110 |
611 |
1 |
Pigmentation |
Minimal |
Moribund |
Special Senses System |
Eye |
|
.1 G/KG |
8 |
18 |
90 |
737 |
1 |
Hemorrhage |
Mild |
Terminal Sacrifice |
Special Senses System |
Eye |
|
.1 G/KG |
8 |
11 |
51 |
667 |
1 |
Synechia |
Mild |
Moribund |
Special Senses System |
Eye |
|
.4 G/KG |
11 |
22 |
110 |
611 |
1 |
Synechia |
Moderate |
Moribund |
Special Senses System |
Eye |
|
.4 G/KG |
11 |
22 |
106 |
730 |
1 |
Synechia |
Mild |
Terminal Sacrifice |
Special Senses System |
Harderian Gland |
|
.4 G/KG |
4 |
22 |
110 |
611 |
1 |
Hyperplasia |
Minimal |
Moribund |
Urinary System |
Kidney |
Artery |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Inflammation |
Mild |
Moribund |
Urinary System |
Kidney |
Cortex |
Vehicle Control |
50 |
2 |
7 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Cortex |
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Cortex |
.1 G/KG |
50 |
12 |
57 |
292 |
1 |
Mineralization |
Mild |
Dead |
Urinary System |
Kidney |
Cortex |
.1 G/KG |
50 |
14 |
68 |
730 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Cortex |
.1 G/KG |
50 |
11 |
52 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Cortex |
.1 G/KG |
50 |
11 |
53 |
735 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Cortex |
.1 G/KG |
50 |
13 |
65 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Cortex |
.1 G/KG |
50 |
14 |
67 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Cortex |
.1 G/KG |
50 |
17 |
83 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Cortex |
.1 G/KG |
50 |
17 |
84 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Cortex |
.1 G/KG |
50 |
19 |
95 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Cortex |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Cortex |
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Mineralization |
Minimal |
Dead |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
6 |
28 |
737 |
1 |
Mineralization |
Minimal |
Dead |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Mineralization |
Minimal |
Dead |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
9 |
44 |
658 |
1 |
Mineralization |
Minimal |
Dead |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
2 |
7 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
2 |
8 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
3 |
11 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
4 |
16 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
7 |
34 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
Vehicle Control |
50 |
9 |
42 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
11 |
54 |
664 |
1 |
Mineralization |
Minimal |
Dead |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
17 |
85 |
503 |
1 |
Mineralization |
Minimal |
Dead |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
20 |
97 |
672 |
1 |
Mineralization |
Minimal |
Dead |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
11 |
51 |
667 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
14 |
68 |
730 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
14 |
69 |
616 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
16 |
79 |
517 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
18 |
87 |
462 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
18 |
89 |
582 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
19 |
93 |
699 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
20 |
98 |
730 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
11 |
53 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
12 |
56 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
12 |
59 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
13 |
62 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
13 |
65 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
14 |
67 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
15 |
72 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
15 |
74 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
16 |
76 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
16 |
80 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
17 |
83 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
17 |
84 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
18 |
86 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
18 |
88 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
18 |
90 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
19 |
94 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
19 |
95 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
20 |
100 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
20 |
96 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.1 G/KG |
50 |
20 |
99 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
23 |
113 |
666 |
1 |
Mineralization |
Minimal |
Dead |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
27 |
131 |
690 |
1 |
Mineralization |
Mild |
Dead |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Mineralization |
Minimal |
Dead |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Mineralization |
Minimal |
Gavage Death |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Mineralization |
Mild |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
26 |
130 |
574 |
1 |
Mineralization |
Mild |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
30 |
146 |
580 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
24 |
120 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
28 |
138 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Papilla |
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
Vehicle Control |
50 |
2 |
10 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
Vehicle Control |
50 |
2 |
8 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
13 |
64 |
631 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
14 |
69 |
616 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
16 |
79 |
517 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
11 |
53 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
12 |
56 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
12 |
60 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
13 |
62 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
14 |
66 |
736 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
17 |
82 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
18 |
88 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
19 |
95 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.1 G/KG |
50 |
20 |
100 |
737 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
29 |
142 |
372 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Mineralization |
Minimal |
Moribund |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis, Transit Epithe |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
14 |
69 |
616 |
1 |
Degeneration |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Hyperplasia |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Pigmentation |
Minimal |
Dead |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Pigmentation |
Minimal |
Dead |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
9 |
44 |
658 |
1 |
Pigmentation |
Minimal |
Dead |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
1 |
1 |
447 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
1 |
5 |
707 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
10 |
50 |
671 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
4 |
18 |
293 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Pigmentation |
Moderate |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
1 |
4 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
2 |
10 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
2 |
7 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
2 |
8 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
3 |
11 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
4 |
16 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
5 |
23 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
5 |
24 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Pigmentation |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
7 |
34 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
8 |
40 |
740 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
9 |
42 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
9 |
43 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
9 |
45 |
738 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
17 |
85 |
503 |
1 |
Pigmentation |
Minimal |
Dead |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
20 |
97 |
672 |
1 |
Pigmentation |
Mild |
Dead |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
11 |
51 |
667 |
1 |
Pigmentation |
Mild |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
11 |
55 |
723 |
1 |
Pigmentation |
Mild |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
13 |
64 |
631 |
1 |
Pigmentation |
Mild |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
14 |
68 |
730 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
14 |
69 |
616 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
15 |
71 |
650 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
15 |
73 |
499 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
16 |
79 |
517 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
18 |
87 |
462 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
19 |
92 |
694 |
1 |
Pigmentation |
Moderate |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
19 |
93 |
699 |
1 |
Pigmentation |
Mild |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
20 |
98 |
730 |
1 |
Pigmentation |
Mild |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
11 |
52 |
735 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
11 |
53 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
12 |
56 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
12 |
58 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
12 |
59 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
12 |
60 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
13 |
61 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
13 |
62 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
13 |
63 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
13 |
65 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
14 |
66 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
14 |
67 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
14 |
70 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
15 |
72 |
736 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
15 |
74 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
15 |
75 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
16 |
76 |
736 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
16 |
77 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
16 |
80 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
17 |
81 |
737 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
17 |
82 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
17 |
83 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
17 |
84 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
18 |
86 |
737 |
1 |
Pigmentation |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
18 |
88 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
18 |
90 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
19 |
91 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
19 |
94 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
19 |
95 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
20 |
100 |
737 |
1 |
Pigmentation |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
20 |
96 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.1 G/KG |
50 |
20 |
99 |
737 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
23 |
113 |
666 |
1 |
Pigmentation |
Minimal |
Dead |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Pigmentation |
Minimal |
Dead |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Pigmentation |
Minimal |
Dead |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Pigmentation |
Minimal |
Dead |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Pigmentation |
Minimal |
Gavage Death |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Pigmentation |
Moderate |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Pigmentation |
Mild |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
23 |
112 |
600 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
23 |
114 |
491 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Pigmentation |
Mild |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Pigmentation |
Moderate |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Pigmentation |
Mild |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Pigmentation |
Mild |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
26 |
130 |
574 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
28 |
136 |
336 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
29 |
142 |
372 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
30 |
146 |
580 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Pigmentation |
Minimal |
Moribund |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
24 |
120 |
735 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
26 |
127 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
26 |
129 |
735 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
28 |
138 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Pigmentation |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Congestion |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
28 |
136 |
336 |
1 |
Congestion |
Mild |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
14 |
66 |
736 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Cyst |
|
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
12 |
57 |
292 |
1 |
Hydronephrosis |
Mild |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
19 |
708 |
1 |
Nephropathy |
Mild |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
28 |
737 |
1 |
Nephropathy |
Mild |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
32 |
653 |
1 |
Nephropathy |
Mild |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
44 |
658 |
1 |
Nephropathy |
Minimal |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
1 |
2 |
610 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
1 |
5 |
707 |
1 |
Nephropathy |
Moderate |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
47 |
730 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
49 |
730 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
50 |
671 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
12 |
720 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
15 |
636 |
1 |
Nephropathy |
Moderate |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
33 |
727 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
1 |
3 |
740 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
1 |
4 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
46 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
48 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
10 |
737 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
6 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
7 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
8 |
737 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
9 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
11 |
738 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
13 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
14 |
737 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
16 |
738 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
17 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
20 |
740 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
21 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
22 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
23 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
24 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
26 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
27 |
740 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
30 |
737 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
31 |
737 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
34 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
35 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
36 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
38 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
39 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
40 |
740 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
41 |
740 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
42 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
43 |
738 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
45 |
738 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
17 |
85 |
503 |
1 |
Nephropathy |
Mild |
Dead |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
20 |
97 |
672 |
1 |
Nephropathy |
Mild |
Dead |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
16 |
78 |
651 |
1 |
Nephropathy |
Minimal |
Gavage Death |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
11 |
51 |
667 |
1 |
Nephropathy |
Moderate |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
11 |
55 |
723 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
13 |
64 |
631 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
14 |
68 |
730 |
1 |
Nephropathy |
Moderate |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
14 |
69 |
616 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
15 |
71 |
650 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
15 |
73 |
499 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
16 |
79 |
517 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
18 |
87 |
462 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
18 |
89 |
582 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
19 |
92 |
694 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
19 |
93 |
699 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
20 |
98 |
730 |
1 |
Nephropathy |
Moderate |
Moribund |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
11 |
52 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
11 |
53 |
735 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
12 |
56 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
12 |
58 |
735 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
12 |
59 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
12 |
60 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
13 |
61 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
13 |
62 |
736 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
13 |
63 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
13 |
65 |
736 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
14 |
66 |
736 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
14 |
67 |
736 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
14 |
70 |
736 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
15 |
72 |
736 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
15 |
74 |
736 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
15 |
75 |
736 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
16 |
76 |
736 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
16 |
77 |
737 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
16 |
80 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
17 |
81 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
17 |
82 |
737 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
17 |
83 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
17 |
84 |
737 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
18 |
86 |
737 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
18 |
88 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
18 |
90 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
19 |
91 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
19 |
94 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
19 |
95 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
20 |
100 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
20 |
96 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.1 G/KG |
50 |
20 |
99 |
737 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
27 |
131 |
690 |
1 |
Nephropathy |
Mild |
Dead |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
28 |
137 |
700 |
1 |
Nephropathy |
Moderate |
Dead |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
29 |
141 |
652 |
1 |
Nephropathy |
Mild |
Dead |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
30 |
147 |
513 |
1 |
Nephropathy |
Minimal |
Dead |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
21 |
103 |
695 |
1 |
Nephropathy |
Mild |
Gavage Death |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
21 |
102 |
708 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
21 |
104 |
588 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
22 |
107 |
727 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
22 |
110 |
611 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
23 |
112 |
600 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
23 |
114 |
491 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
23 |
115 |
723 |
1 |
Nephropathy |
Moderate |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
24 |
116 |
706 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
24 |
119 |
703 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
25 |
121 |
704 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
25 |
122 |
713 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
25 |
124 |
704 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
25 |
125 |
499 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
26 |
130 |
574 |
1 |
Nephropathy |
Moderate |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
28 |
139 |
730 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
29 |
142 |
372 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
29 |
143 |
660 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
29 |
144 |
707 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
30 |
146 |
580 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
30 |
148 |
670 |
1 |
Nephropathy |
Mild |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
30 |
150 |
562 |
1 |
Nephropathy |
Minimal |
Moribund |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
21 |
101 |
730 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
21 |
105 |
730 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
22 |
106 |
730 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
22 |
108 |
730 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
23 |
111 |
730 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
24 |
117 |
730 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
24 |
118 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
24 |
120 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
25 |
123 |
730 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
26 |
126 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
26 |
127 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
26 |
128 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
26 |
129 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
27 |
132 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
27 |
133 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
27 |
134 |
735 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
27 |
135 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
28 |
138 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
28 |
140 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
29 |
145 |
735 |
1 |
Nephropathy |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
.4 G/KG |
50 |
30 |
149 |
735 |
1 |
Nephropathy |
Mild |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Calculus Gross Observation |
|
Moribund |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Calculus Gross Observation |
|
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
.1 G/KG |
10 |
17 |
85 |
503 |
1 |
Calculus Gross Observation |
|
Dead |
Urinary System |
Urinary Bladder |
|
.1 G/KG |
10 |
12 |
60 |
735 |
1 |
Calculus Gross Observation |
|
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
50 |
5 |
25 |
597 |
1 |
Calculus Micro Observation Only |
|
Moribund |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
50 |
8 |
37 |
551 |
1 |
Calculus Micro Observation Only |
|
Moribund |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
50 |
6 |
29 |
737 |
1 |
Calculus Micro Observation Only |
|
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
.1 G/KG |
10 |
17 |
85 |
503 |
1 |
Calculus Micro Observation Only |
|
Dead |
Urinary System |
Urinary Bladder |
|
.1 G/KG |
10 |
12 |
60 |
735 |
1 |
Calculus Micro Observation Only |
|
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
.4 G/KG |
50 |
22 |
109 |
457 |
1 |
Calculus Micro Observation Only |
|
Moribund |
Urinary System |
Urinary Bladder |
|
.1 G/KG |
10 |
12 |
57 |
292 |
1 |
Hemorrhage |
Moderate |
Dead |
Urinary System |
Urinary Bladder |
|
.1 G/KG |
10 |
12 |
57 |
292 |
1 |
Necrosis |
Moderate |
Dead |