Alimentary System |
Intestine Large |
Colon |
37.5 MG/KG |
50 |
51 |
150 |
688 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Alimentary System |
Intestine Large |
Rectum |
Vehicle Control |
50 |
13 |
38 |
727 |
1 |
Mesothelioma Malignant |
Metastatic |
Terminal Sacrifice |
Alimentary System |
Intestine Small |
Duodenum |
75 MG/KG |
50 |
62 |
181 |
394 |
1 |
Carcinoma |
|
Natural Death |
Alimentary System |
Intestine Small |
Duodenum |
Vehicle Control |
50 |
14 |
42 |
699 |
1 |
Mesothelioma Malignant |
Metastatic |
Natural Death |
Alimentary System |
Intestine Small |
Ileum |
37.5 MG/KG |
50 |
51 |
150 |
688 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Alimentary System |
Intestine Small |
Jejunum |
18.75 MG/KG |
50 |
20 |
59 |
727 |
1 |
Lipoma |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
6 |
728 |
1 |
Hepatocellular Adenoma |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
37.5 MG/KG |
50 |
50 |
147 |
728 |
1 |
Hepatocellular Adenoma |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
75 MG/KG |
50 |
65 |
190 |
561 |
1 |
Hepatocellular Adenoma |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
16 |
48 |
709 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
12 |
34 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
18.75 MG/KG |
50 |
24 |
69 |
199 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Alimentary System |
Liver |
|
18.75 MG/KG |
50 |
20 |
59 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
18.75 MG/KG |
50 |
31 |
90 |
728 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
18.75 MG/KG |
50 |
33 |
96 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Alimentary System |
Liver |
|
37.5 MG/KG |
50 |
38 |
110 |
705 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Alimentary System |
Liver |
|
37.5 MG/KG |
50 |
49 |
144 |
598 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Alimentary System |
Liver |
|
37.5 MG/KG |
50 |
50 |
147 |
728 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
14 |
42 |
699 |
1 |
Mesothelioma Malignant |
Metastatic |
Natural Death |
Alimentary System |
Liver |
|
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Mesothelioma Malignant |
Metastatic |
Moribund Sacrifice |
Alimentary System |
Liver |
|
37.5 MG/KG |
50 |
51 |
150 |
688 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Alimentary System |
Mesentery |
|
18.75 MG/KG |
11 |
29 |
86 |
632 |
1 |
Carcinoma |
Metastatic |
Moribund Sacrifice |
Alimentary System |
Mesentery |
|
Vehicle Control |
9 |
14 |
42 |
699 |
1 |
Mesothelioma Malignant |
Metastatic |
Natural Death |
Alimentary System |
Mesentery |
|
Vehicle Control |
9 |
13 |
38 |
727 |
1 |
Mesothelioma Malignant |
Metastatic |
Terminal Sacrifice |
Alimentary System |
Mesentery |
|
37.5 MG/KG |
11 |
51 |
150 |
688 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Alimentary System |
Oral Mucosa |
Pharyngeal |
18.75 MG/KG |
1 |
27 |
78 |
728 |
1 |
Squamous Cell Carcinoma |
|
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
Vehicle Control |
50 |
7 |
20 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
Vehicle Control |
50 |
9 |
27 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
18.75 MG/KG |
50 |
20 |
58 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
18.75 MG/KG |
50 |
22 |
63 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
18.75 MG/KG |
50 |
28 |
82 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
18.75 MG/KG |
50 |
29 |
86 |
632 |
1 |
Carcinoma |
Metastatic |
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
Vehicle Control |
50 |
14 |
42 |
699 |
1 |
Mesothelioma Malignant |
Metastatic |
Natural Death |
Alimentary System |
Pancreas |
|
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Mesothelioma Malignant |
Metastatic |
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
37.5 MG/KG |
50 |
51 |
150 |
688 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Alimentary System |
Salivary Glands |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
|
18.75 MG/KG |
50 |
26 |
75 |
672 |
1 |
Schwannoma Malignant |
Metastatic |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Mesothelioma Malignant |
Metastatic |
Moribund Sacrifice |
Alimentary System |
Tongue |
|
18.75 MG/KG |
1 |
23 |
66 |
727 |
1 |
Squamous Cell Papilloma |
|
Terminal Sacrifice |
Alimentary System |
Tongue |
|
37.5 MG/KG |
2 |
40 |
118 |
725 |
1 |
Squamous Cell Papilloma |
|
Natural Death |
Alimentary System |
Tongue |
|
37.5 MG/KG |
2 |
37 |
109 |
728 |
1 |
Squamous Cell Papilloma |
|
Terminal Sacrifice |
Alimentary System |
Tooth |
|
18.75 MG/KG |
2 |
32 |
95 |
639 |
1 |
Odontoma |
|
Natural Death |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Cardiovascular System |
Heart |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Cardiovascular System |
Heart |
|
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
|
Vehicle Control |
50 |
3 |
7 |
692 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
|
Vehicle Control |
50 |
6 |
18 |
701 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
|
37.5 MG/KG |
50 |
37 |
108 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
|
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
|
37.5 MG/KG |
50 |
38 |
110 |
705 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
38 |
110 |
705 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
16 |
48 |
709 |
1 |
Pheochromocytoma Benign |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
14 |
42 |
699 |
1 |
Pheochromocytoma Benign |
|
Natural Death |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
11 |
32 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
12 |
35 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
15 |
43 |
728 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
16 |
47 |
728 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
8 |
23 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
50 |
9 |
26 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Pheochromocytoma Benign |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
32 |
94 |
644 |
1 |
Pheochromocytoma Benign |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
19 |
55 |
611 |
1 |
Pheochromocytoma Benign |
|
Natural Death |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
18 |
52 |
728 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
18 |
53 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
20 |
59 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
22 |
65 |
728 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
Multiple |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
24 |
71 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
25 |
72 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
27 |
78 |
728 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
28 |
81 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
33 |
98 |
728 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
36 |
104 |
701 |
1 |
Pheochromocytoma Benign |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
44 |
129 |
608 |
1 |
Pheochromocytoma Benign |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Pheochromocytoma Benign |
|
Moribund Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
35 |
103 |
637 |
1 |
Pheochromocytoma Benign |
|
Natural Death |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
40 |
118 |
725 |
1 |
Pheochromocytoma Benign |
|
Natural Death |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
35 |
101 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
37 |
108 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
38 |
111 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
38 |
112 |
728 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
39 |
115 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
41 |
119 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
47 |
138 |
728 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
75 MG/KG |
50 |
62 |
183 |
727 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
75 MG/KG |
50 |
65 |
191 |
728 |
1 |
Pheochromocytoma Benign |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
26 |
75 |
672 |
1 |
Pheochromocytoma Malignant |
|
Natural Death |
Endocrine System |
Adrenal Medulla |
|
18.75 MG/KG |
50 |
30 |
89 |
638 |
1 |
Pheochromocytoma Malignant |
|
Natural Death |
Endocrine System |
Adrenal Medulla |
|
37.5 MG/KG |
50 |
37 |
109 |
728 |
1 |
Pheochromocytoma Malignant |
|
Terminal Sacrifice |
Endocrine System |
Islets |
Pancreatic |
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Islets |
Pancreatic |
Vehicle Control |
50 |
5 |
13 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Parathyroid Gland |
|
Vehicle Control |
50 |
15 |
43 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
3 |
7 |
692 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
14 |
41 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
15 |
44 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
16 |
47 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
17 |
49 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
2 |
4 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
5 |
13 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
6 |
17 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
8 |
23 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
9 |
27 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
23 |
68 |
682 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
29 |
86 |
632 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
34 |
100 |
701 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
29 |
85 |
580 |
1 |
Adenoma |
|
Natural Death |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
18 |
51 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
18 |
52 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
21 |
61 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
22 |
64 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
25 |
73 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
26 |
76 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
26 |
77 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
27 |
78 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
18.75 MG/KG |
50 |
27 |
79 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
40 |
117 |
594 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
45 |
133 |
682 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
39 |
114 |
641 |
1 |
Adenoma |
|
Natural Death |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
40 |
116 |
636 |
1 |
Adenoma |
|
Natural Death |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
41 |
120 |
632 |
1 |
Adenoma |
|
Natural Death |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
45 |
132 |
724 |
1 |
Adenoma |
|
Natural Death |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
36 |
106 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
37 |
107 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
39 |
115 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
42 |
122 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
43 |
127 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
44 |
128 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
47 |
137 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
49 |
143 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
50 |
146 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
37.5 MG/KG |
50 |
51 |
149 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
75 MG/KG |
50 |
54 |
157 |
650 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Endocrine System |
Pituitary Gland |
|
37.5 MG/KG |
50 |
38 |
110 |
705 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Endocrine System |
Pituitary Gland |
|
Vehicle Control |
50 |
3 |
7 |
692 |
1 |
Squamous Cell Carcinoma |
Metastatic |
Moribund Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
13 |
39 |
632 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
6 |
18 |
701 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
8 |
22 |
723 |
1 |
Adenoma |
|
Natural Death |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
10 |
28 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
11 |
32 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
11 |
33 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
9 |
27 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
18.75 MG/KG |
50 |
30 |
88 |
605 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
18.75 MG/KG |
50 |
22 |
64 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
18.75 MG/KG |
50 |
23 |
67 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
18.75 MG/KG |
50 |
24 |
71 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
18.75 MG/KG |
50 |
25 |
74 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
18.75 MG/KG |
50 |
27 |
79 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
18.75 MG/KG |
50 |
33 |
97 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
37.5 MG/KG |
50 |
40 |
117 |
594 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
37.5 MG/KG |
50 |
46 |
134 |
701 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
37.5 MG/KG |
50 |
47 |
138 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
37.5 MG/KG |
50 |
48 |
140 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
75 MG/KG |
50 |
67 |
196 |
388 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Thyroid Gland |
Follicular Cel |
18.75 MG/KG |
50 |
29 |
86 |
632 |
1 |
Adenoma |
|
Moribund Sacrifice |
Endocrine System |
Thyroid Gland |
Follicular Cel |
18.75 MG/KG |
50 |
24 |
71 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
Follicular Cel |
18.75 MG/KG |
50 |
26 |
76 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
Follicular Cel |
18.75 MG/KG |
50 |
26 |
77 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
Follicular Cel |
37.5 MG/KG |
50 |
38 |
112 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
Follicular Cel |
37.5 MG/KG |
50 |
41 |
121 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
Follicular Cel |
75 MG/KG |
50 |
57 |
166 |
605 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Epididymis |
|
18.75 MG/KG |
50 |
18 |
51 |
728 |
1 |
Mesothelioma Benign |
|
Terminal Sacrifice |
Genital System |
Epididymis |
|
18.75 MG/KG |
50 |
27 |
79 |
727 |
1 |
Mesothelioma Benign |
|
Terminal Sacrifice |
Genital System |
Epididymis |
|
37.5 MG/KG |
50 |
37 |
109 |
728 |
1 |
Mesothelioma Benign |
|
Terminal Sacrifice |
Genital System |
Epididymis |
|
Vehicle Control |
50 |
14 |
42 |
699 |
1 |
Mesothelioma Malignant |
|
Natural Death |
Genital System |
Epididymis |
|
Vehicle Control |
50 |
13 |
38 |
727 |
1 |
Mesothelioma Malignant |
|
Terminal Sacrifice |
Genital System |
Epididymis |
|
37.5 MG/KG |
50 |
36 |
106 |
727 |
1 |
Mesothelioma Malignant |
|
Terminal Sacrifice |
Genital System |
Epididymis |
|
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Mesothelioma Malignant |
|
Moribund Sacrifice |
Genital System |
Epididymis |
|
37.5 MG/KG |
50 |
51 |
150 |
688 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
2 |
5 |
653 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
12 |
35 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
4 |
12 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
18.75 MG/KG |
50 |
21 |
60 |
451 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Preputial Gland |
|
18.75 MG/KG |
50 |
24 |
70 |
673 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Preputial Gland |
|
18.75 MG/KG |
50 |
34 |
100 |
701 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Preputial Gland |
|
18.75 MG/KG |
50 |
20 |
57 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
18.75 MG/KG |
50 |
21 |
61 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
37.5 MG/KG |
50 |
45 |
132 |
724 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Preputial Gland |
|
37.5 MG/KG |
50 |
36 |
106 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
75 MG/KG |
50 |
61 |
180 |
497 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Preputial Gland |
|
Vehicle Control |
50 |
12 |
34 |
727 |
1 |
Carcinoma |
|
Terminal Sacrifice |
Genital System |
Prostate |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
14 |
42 |
699 |
1 |
Mesothelioma Malignant |
Metastatic |
Natural Death |
Genital System |
Prostate |
|
Vehicle Control |
50 |
13 |
38 |
727 |
1 |
Mesothelioma Malignant |
Metastatic |
Terminal Sacrifice |
Genital System |
Prostate |
|
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Mesothelioma Malignant |
Metastatic |
Moribund Sacrifice |
Genital System |
Seminal Vesicle |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Genital System |
Seminal Vesicle |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Genital System |
Seminal Vesicle |
|
Vehicle Control |
50 |
14 |
42 |
699 |
1 |
Mesothelioma Malignant |
Metastatic |
Natural Death |
Genital System |
Seminal Vesicle |
|
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Mesothelioma Malignant |
Metastatic |
Moribund Sacrifice |
Genital System |
Seminal Vesicle |
|
37.5 MG/KG |
50 |
51 |
150 |
688 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
13 |
39 |
632 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
16 |
48 |
709 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
2 |
5 |
653 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
6 |
18 |
701 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
14 |
42 |
699 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
8 |
22 |
723 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
1 |
2 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
1 |
3 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
10 |
28 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
10 |
29 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
11 |
31 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
11 |
32 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
11 |
33 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
12 |
34 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
12 |
35 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
12 |
36 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
13 |
37 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
13 |
38 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
14 |
41 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
15 |
43 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
15 |
44 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
16 |
46 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
16 |
47 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
17 |
49 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
2 |
4 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
2 |
6 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
3 |
8 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
3 |
9 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
4 |
10 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
4 |
11 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
4 |
12 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
5 |
13 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
5 |
15 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
6 |
16 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
6 |
17 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
7 |
20 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
7 |
21 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
9 |
25 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
Vehicle Control |
50 |
9 |
26 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
19 |
56 |
622 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
21 |
62 |
709 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
23 |
68 |
682 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
30 |
88 |
605 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
32 |
94 |
644 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
34 |
100 |
701 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
19 |
55 |
611 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
26 |
75 |
672 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
28 |
83 |
570 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
30 |
89 |
638 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
32 |
95 |
639 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
18 |
52 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
18 |
53 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
20 |
57 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
20 |
58 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
20 |
59 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
21 |
61 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
22 |
63 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
22 |
64 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
22 |
65 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
23 |
67 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
25 |
72 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
25 |
73 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
25 |
74 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
26 |
76 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
27 |
78 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
28 |
81 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
30 |
87 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
31 |
90 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
31 |
91 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
31 |
92 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
32 |
93 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
33 |
96 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
33 |
97 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
18.75 MG/KG |
50 |
34 |
99 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
36 |
104 |
701 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
40 |
117 |
594 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
42 |
123 |
673 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
44 |
129 |
608 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
45 |
133 |
682 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
46 |
134 |
701 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
35 |
102 |
697 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
35 |
103 |
637 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
39 |
114 |
641 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
45 |
132 |
724 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
49 |
144 |
598 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
51 |
150 |
688 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
35 |
101 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
36 |
105 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
36 |
106 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
37 |
107 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
37 |
108 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
37 |
109 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
38 |
111 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
41 |
119 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
41 |
121 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
42 |
124 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
43 |
125 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
43 |
126 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
43 |
127 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
44 |
128 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
45 |
131 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
47 |
137 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
47 |
138 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
48 |
140 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
48 |
141 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
48 |
142 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
49 |
143 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
50 |
147 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
50 |
148 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
37.5 MG/KG |
50 |
51 |
149 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
52 |
151 |
414 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
52 |
153 |
615 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
53 |
154 |
533 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
53 |
155 |
703 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
54 |
158 |
476 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
54 |
159 |
591 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
55 |
160 |
511 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
56 |
164 |
490 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
56 |
165 |
587 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
57 |
166 |
605 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
57 |
167 |
547 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
59 |
173 |
684 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
60 |
177 |
634 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
63 |
185 |
414 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
64 |
189 |
561 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
67 |
196 |
388 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
67 |
198 |
622 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
60 |
175 |
570 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
61 |
179 |
499 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
61 |
180 |
497 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
62 |
182 |
532 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
65 |
192 |
635 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
66 |
194 |
502 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
62 |
183 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Bilateral, Interstit Cell |
75 MG/KG |
50 |
65 |
191 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
1 |
1 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
10 |
30 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
8 |
23 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
8 |
24 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
9 |
27 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
18.75 MG/KG |
50 |
21 |
60 |
451 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
18.75 MG/KG |
50 |
24 |
70 |
673 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
18.75 MG/KG |
50 |
29 |
86 |
632 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
18.75 MG/KG |
50 |
29 |
85 |
580 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Interstit Cell |
18.75 MG/KG |
50 |
24 |
71 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
18.75 MG/KG |
50 |
27 |
79 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
18.75 MG/KG |
50 |
27 |
80 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
18.75 MG/KG |
50 |
33 |
98 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
37.5 MG/KG |
50 |
44 |
130 |
465 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
37.5 MG/KG |
50 |
46 |
136 |
455 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
37.5 MG/KG |
50 |
38 |
112 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
37.5 MG/KG |
50 |
39 |
115 |
727 |
1 |
Adenoma |
|
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
54 |
157 |
650 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
55 |
161 |
377 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
55 |
162 |
545 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
58 |
170 |
407 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
59 |
174 |
366 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
60 |
176 |
503 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
61 |
178 |
407 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
63 |
184 |
539 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
63 |
186 |
407 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
64 |
188 |
414 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
65 |
190 |
561 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
68 |
200 |
407 |
1 |
Adenoma |
|
Moribund Sacrifice |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
52 |
152 |
602 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
53 |
156 |
503 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
56 |
163 |
510 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
58 |
169 |
360 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
58 |
171 |
535 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
Interstit Cell |
75 MG/KG |
50 |
59 |
172 |
525 |
1 |
Adenoma |
|
Natural Death |
Genital System |
Testes |
|
18.75 MG/KG |
50 |
27 |
79 |
727 |
1 |
Mesothelioma Benign |
|
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
13 |
38 |
727 |
1 |
Mesothelioma Malignant |
Metastatic |
Terminal Sacrifice |
Genital System |
Testes |
|
37.5 MG/KG |
50 |
36 |
106 |
727 |
1 |
Mesothelioma Malignant |
|
Terminal Sacrifice |
Genital System |
Testes |
|
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Mesothelioma Malignant |
Metastatic |
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
18.75 MG/KG |
50 |
24 |
69 |
199 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Hematopoietic System |
Bone Marrow |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Bone Marrow |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Bone Marrow |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Deep Cervical |
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Deep Cervical |
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
18.75 MG/KG |
50 |
21 |
62 |
709 |
1 |
Alveolar/Bronchiolar Carcinoma |
Metastatic |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
18.75 MG/KG |
50 |
33 |
96 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
37.5 MG/KG |
50 |
50 |
147 |
728 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
37.5 MG/KG |
50 |
51 |
150 |
688 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Hematopoietic System |
Lymph Node |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
16 |
48 |
709 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
12 |
34 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
18.75 MG/KG |
50 |
24 |
69 |
199 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Hematopoietic System |
Spleen |
|
18.75 MG/KG |
50 |
20 |
59 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
18.75 MG/KG |
50 |
31 |
90 |
728 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
18.75 MG/KG |
50 |
33 |
96 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
37.5 MG/KG |
50 |
38 |
110 |
705 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Hematopoietic System |
Spleen |
|
37.5 MG/KG |
50 |
49 |
144 |
598 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Hematopoietic System |
Spleen |
|
37.5 MG/KG |
50 |
50 |
147 |
728 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
13 |
38 |
727 |
1 |
Mesothelioma Malignant |
Metastatic |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Mesothelioma Malignant |
Metastatic |
Moribund Sacrifice |
Hematopoietic System |
Spleen |
|
37.5 MG/KG |
50 |
51 |
150 |
688 |
1 |
Osteosarcoma |
|
Natural Death |
Hematopoietic System |
Thymus |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
18.75 MG/KG |
50 |
24 |
69 |
199 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Hematopoietic System |
Thymus |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
18.75 MG/KG |
50 |
26 |
75 |
672 |
1 |
Schwannoma Malignant |
Metastatic |
Natural Death |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
50 |
13 |
39 |
632 |
1 |
Fibroadenoma |
|
Moribund Sacrifice |
Integumentary System |
Mammary Gland |
|
18.75 MG/KG |
50 |
34 |
100 |
701 |
1 |
Fibroadenoma |
|
Moribund Sacrifice |
Integumentary System |
Mammary Gland |
|
18.75 MG/KG |
50 |
20 |
58 |
728 |
1 |
Fibroadenoma |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
18.75 MG/KG |
50 |
31 |
91 |
727 |
1 |
Fibroadenoma |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Fibroadenoma |
|
Moribund Sacrifice |
Integumentary System |
Mammary Gland |
|
75 MG/KG |
50 |
56 |
165 |
587 |
1 |
Fibroadenoma |
|
Moribund Sacrifice |
Integumentary System |
Skin |
Pinna |
75 MG/KG |
50 |
65 |
191 |
728 |
1 |
Squamous Cell Papilloma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
Vehicle Control |
50 |
14 |
41 |
727 |
1 |
Fibroma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
Vehicle Control |
50 |
15 |
44 |
728 |
1 |
Fibroma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
Vehicle Control |
50 |
7 |
21 |
728 |
1 |
Fibroma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
18.75 MG/KG |
50 |
30 |
88 |
605 |
1 |
Fibroma |
|
Moribund Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
18.75 MG/KG |
50 |
33 |
98 |
728 |
1 |
Fibroma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
37.5 MG/KG |
50 |
44 |
129 |
608 |
1 |
Fibroma |
|
Moribund Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
37.5 MG/KG |
50 |
46 |
136 |
455 |
1 |
Fibroma |
|
Moribund Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
37.5 MG/KG |
50 |
44 |
128 |
727 |
1 |
Fibroma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
37.5 MG/KG |
50 |
36 |
104 |
701 |
1 |
Fibrous Histiocytoma |
|
Moribund Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Schwannoma Malignant |
|
Moribund Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
Vehicle Control |
50 |
6 |
18 |
701 |
1 |
Schwannoma Malignant |
|
Moribund Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
18.75 MG/KG |
50 |
26 |
75 |
672 |
1 |
Schwannoma Malignant |
|
Natural Death |
Integumentary System |
Skin |
Subcut Tiss |
18.75 MG/KG |
50 |
20 |
57 |
727 |
1 |
Schwannoma Malignant |
|
Terminal Sacrifice |
Integumentary System |
Skin |
Subcut Tiss |
37.5 MG/KG |
50 |
39 |
114 |
641 |
1 |
Schwannoma Malignant |
|
Natural Death |
Integumentary System |
Skin |
|
37.5 MG/KG |
50 |
49 |
143 |
727 |
1 |
Basal Cell Adenoma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Basal Cell Adenoma |
|
Moribund Sacrifice |
Integumentary System |
Skin |
|
18.75 MG/KG |
50 |
22 |
65 |
728 |
1 |
Basal Cell Carcinoma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
18.75 MG/KG |
50 |
30 |
87 |
727 |
1 |
Basal Cell Carcinoma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
75 MG/KG |
50 |
64 |
189 |
561 |
1 |
Fibrous Histiocytoma |
|
Moribund Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
17 |
49 |
727 |
1 |
Keratoacanthoma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Keratoacanthoma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
9 |
25 |
727 |
1 |
Keratoacanthoma |
|
Terminal Sacrifice |
Integumentary System |
Skin |
|
37.5 MG/KG |
50 |
35 |
102 |
697 |
1 |
Keratoacanthoma |
|
Natural Death |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
16 |
48 |
709 |
1 |
Schwannoma Malignant |
|
Moribund Sacrifice |
Integumentary System |
Skin |
|
18.75 MG/KG |
50 |
24 |
71 |
727 |
1 |
Squamous Cell Carcinoma |
|
Terminal Sacrifice |
Musculoskeletal System |
Bone |
Maxilla |
18.75 MG/KG |
50 |
19 |
56 |
622 |
1 |
Osteosarcoma |
|
Moribund Sacrifice |
Musculoskeletal System |
Skeletal Muscle |
Perimysium |
37.5 MG/KG |
1 |
51 |
150 |
688 |
1 |
Osteosarcoma |
Metastatic |
Natural Death |
Nervous System |
Brain |
|
Vehicle Control |
50 |
15 |
44 |
728 |
1 |
Astrocytoma Malignant |
|
Terminal Sacrifice |
Nervous System |
Brain |
|
18.75 MG/KG |
50 |
20 |
59 |
727 |
1 |
Astrocytoma Malignant |
|
Terminal Sacrifice |
Nervous System |
Brain |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Nervous System |
Brain |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Nervous System |
Brain |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Nervous System |
Brain |
|
37.5 MG/KG |
50 |
44 |
130 |
465 |
1 |
Meningioma Malignant |
|
Moribund Sacrifice |
Nervous System |
Brain |
|
Vehicle Control |
50 |
3 |
7 |
692 |
1 |
Squamous Cell Carcinoma |
Metastatic |
Moribund Sacrifice |
Respiratory System |
Lung |
Alveolus |
18.75 MG/KG |
50 |
30 |
89 |
638 |
1 |
Pheochromocytoma Malignant |
Metastatic |
Natural Death |
Respiratory System |
Lung |
|
18.75 MG/KG |
50 |
28 |
82 |
728 |
1 |
Alveolar/Bronchiolar Adenoma |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
48 |
142 |
728 |
1 |
Alveolar/Bronchiolar Adenoma |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
50 |
146 |
728 |
1 |
Alveolar/Bronchiolar Adenoma |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
51 |
149 |
727 |
1 |
Alveolar/Bronchiolar Adenoma |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
14 |
41 |
727 |
1 |
Alveolar/Bronchiolar Carcinoma |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
18.75 MG/KG |
50 |
21 |
62 |
709 |
1 |
Alveolar/Bronchiolar Carcinoma |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
41 |
119 |
727 |
1 |
Alveolar/Bronchiolar Carcinoma |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
18.75 MG/KG |
50 |
29 |
86 |
632 |
1 |
Carcinoma |
Metastatic |
Moribund Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
16 |
48 |
709 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
18.75 MG/KG |
50 |
24 |
69 |
199 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Respiratory System |
Lung |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
18.75 MG/KG |
50 |
33 |
96 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
38 |
110 |
705 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
44 |
130 |
465 |
1 |
Meningioma Malignant |
Metastatic |
Moribund Sacrifice |
Respiratory System |
Lung |
|
37.5 MG/KG |
50 |
40 |
117 |
594 |
1 |
Squamous Cell Carcinoma |
|
Moribund Sacrifice |
Respiratory System |
Nose |
|
Vehicle Control |
50 |
3 |
7 |
692 |
1 |
Squamous Cell Carcinoma |
|
Moribund Sacrifice |
Special Senses System |
Eye |
|
Vehicle Control |
50 |
3 |
7 |
692 |
1 |
Squamous Cell Carcinoma |
Metastatic |
Moribund Sacrifice |
Special Senses System |
Harderian Gland |
|
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Special Senses System |
Harderian Gland |
|
Vehicle Control |
50 |
3 |
7 |
692 |
1 |
Squamous Cell Carcinoma |
Metastatic |
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
Vehicle Control |
50 |
6 |
17 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
37.5 MG/KG |
50 |
42 |
123 |
673 |
1 |
Adenoma |
|
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
37.5 MG/KG |
50 |
43 |
127 |
728 |
1 |
Adenoma |
|
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
75 MG/KG |
50 |
54 |
157 |
650 |
1 |
Adenoma |
|
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
75 MG/KG |
50 |
66 |
193 |
673 |
1 |
Adenoma |
|
Moribund Sacrifice |
Urinary System |
Kidney |
|
18.75 MG/KG |
50 |
29 |
86 |
632 |
1 |
Carcinoma |
|
Moribund Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
14 |
40 |
627 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
12 |
34 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
18.75 MG/KG |
50 |
29 |
84 |
713 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Urinary System |
Kidney |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
18.75 MG/KG |
50 |
33 |
96 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Urinary System |
Kidney |
|
37.5 MG/KG |
50 |
47 |
139 |
675 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Urinary System |
Kidney |
|
37.5 MG/KG |
50 |
49 |
145 |
659 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |
Urinary System |
Kidney |
|
37.5 MG/KG |
50 |
38 |
110 |
705 |
1 |
Leukemia Mononuclear |
|
Natural Death |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
50 |
17 |
50 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
18.75 MG/KG |
50 |
23 |
66 |
727 |
1 |
Leukemia Mononuclear |
|
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
37.5 MG/KG |
50 |
46 |
135 |
639 |
1 |
Leukemia Mononuclear |
|
Moribund Sacrifice |