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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Riddelliine |
CASRN: | ="23246-96-0" |
Study Number: | C61358C |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | GAVAGE |
TDMS Number: | 0516106 |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (MG/KG/DY) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 188 |
46 |
0 |
|
38.6 |
|
Day 356 |
206 |
3.0 |
|
37.2 |
|
Day 434 |
88 |
0.1 |
|
47.1 |
|
Day 475 |
29 |
0 |
|
|
|
Day 486 |
39 |
0 |
|
41.1 |
|
Day 507 |
159 |
1.0 |
|
34.4 |
|
Day 531 |
187 |
1.0 |
|
|
|
Day 542 |
84 |
0.1 |
|
24.4 |
|
Day 550 |
208 |
3.0 |
|
|
|
Day 552 |
197 |
1.0 |
|
|
|
Day 554 |
155 |
1.0 |
|
46.5 |
|
Day 559 |
241 |
3.0 |
|
|
|
Day 561 |
19 |
0 |
|
|
|
Day 566 |
79 |
0.1 |
|
|
|
Day 566 |
178 |
1.0 |
|
|
|
Day 566 |
237 |
3.0 |
|
30.2 |
|
Day 567 |
122 |
0.3 |
|
|
|
Day 568 |
211 |
3.0 |
|
|
|
Day 572 |
226 |
3.0 |
|
|
|
Day 577 |
236 |
3.0 |
|
29.4 |
|
Day 582 |
168 |
1.0 |
|
|
|
Day 587 |
60 |
0.1 |
|
|
|
Day 587 |
201 |
3.0 |
|
28.4 |
|
Day 590 |
249 |
3.0 |
|
31.2 |
|
Day 592 |
102 |
0.3 |
|
|
|
Day 596 |
58 |
0.1 |
|
49.7 |
|
Day 598 |
229 |
3.0 |
|
45.8 |
|
Day 599 |
33 |
0 |
|
|
|
Day 603 |
233 |
3.0 |
|
|
|
Day 603 |
234 |
3.0 |
|
|
|
Day 605 |
239 |
3.0 |
|
38.6 |
|
Day 614 |
111 |
0.3 |
|
|
|
Day 614 |
225 |
3.0 |
|
|
|
Day 619 |
137 |
0.3 |
|
|
|
Day 633 |
13 |
0 |
|
|
|
Day 633 |
92 |
0.1 |
|
27.5 |
|
Day 633 |
212 |
3.0 |
|
55.3 |
|
Day 634 |
86 |
0.1 |
|
|
|
Day 637 |
40 |
0 |
|
|
|
Day 639 |
157 |
1.0 |
|
|
|
Day 639 |
203 |
3.0 |
|
|
|
Day 644 |
240 |
3.0 |
|
|
|
Day 647 |
221 |
3.0 |
|
|
|
Day 652 |
238 |
3.0 |
|
25 |
|
Day 657 |
110 |
0.3 |
|
51.1 |
|
Day 660 |
214 |
3.0 |
|
42.5 |
|
Day 661 |
165 |
1.0 |
|
|
|
Day 661 |
194 |
1.0 |
|
46.9 |
|
Day 661 |
250 |
3.0 |
|
25.2 |
|
Day 664 |
204 |
3.0 |
|
|
|
Day 675 |
32 |
0 |
|
30 |
|
Day 675 |
227 |
3.0 |
|
36.1 |
|
Day 681 |
59 |
0.1 |
|
44.3 |
|
Day 681 |
213 |
3.0 |
|
|
|
Day 685 |
243 |
3.0 |
|
|
|
Day 689 |
188 |
1.0 |
|
37.9 |
|
Day 696 |
97 |
0.1 |
|
36.1 |
|
Day 700 |
142 |
0.3 |
|
42.2 |
|
Day 705 |
209 |
3.0 |
|
|
|
Day 705 |
232 |
3.0 |
|
|
|
Day 706 |
45 |
0 |
|
|
|
Day 707 |
156 |
1.0 |
|
32.2 |
|
Day 713 |
25 |
0 |
|
32 |
|
Day 713 |
4 |
0 |
|
28.4 |
|
Day 713 |
134 |
0.3 |
|
|
|
Day 716 |
244 |
3.0 |
|
|
|
Day 720 |
106 |
0.3 |
|
|
|
Day 720 |
186 |
1.0 |
|
32.8 |
|
Day 720 |
248 |
3.0 |
|
29.4 |
|
Day 722 |
148 |
0.3 |
|
26.1 |
|
Day 727 |
202 |
3.0 |
|
|
|
Day 728 |
139 |
0.3 |
|
|
|
Day 729 |
10 |
0 |
|
58.8 |
|
Day 729 |
12 |
0 |
|
46.4 |
|
Day 729 |
16 |
0 |
|
42.8 |
|
Day 729 |
20 |
0 |
|
49.7 |
|
Day 729 |
22 |
0 |
|
55.9 |
|
Day 729 |
28 |
0 |
|
58.2 |
|
Day 729 |
30 |
0 |
|
39.9 |
|
Day 729 |
35 |
0 |
|
58 |
|
Day 729 |
41 |
0 |
|
45.7 |
|
Day 729 |
42 |
0 |
|
40.2 |
|
Day 729 |
47 |
0 |
|
30.8 |
|
Day 729 |
48 |
0 |
|
55.2 |
|
Day 729 |
49 |
0 |
|
54.6 |
|
Day 729 |
6 |
0 |
|
55.4 |
|
Day 729 |
8 |
0 |
|
53.8 |
|
Day 729 |
9 |
0 |
|
36.5 |
|
Day 729 |
54 |
0.1 |
|
43 |
|
Day 729 |
56 |
0.1 |
|
44.6 |
|
Day 729 |
63 |
0.1 |
|
55.1 |
|
Day 729 |
66 |
0.1 |
|
60.1 |
|
Day 729 |
69 |
0.1 |
|
40.8 |
|
Day 729 |
73 |
0.1 |
|
55 |
|
Day 729 |
80 |
0.1 |
|
54.4 |
|
Day 729 |
85 |
0.1 |
|
34.5 |
|
Day 729 |
89 |
0.1 |
|
51.5 |
|
Day 729 |
90 |
0.1 |
|
28.8 |
|
Day 729 |
103 |
0.3 |
|
54.6 |
|
Day 729 |
105 |
0.3 |
|
47.4 |
|
Day 729 |
107 |
0.3 |
|
50.9 |
|
Day 729 |
113 |
0.3 |
|
55 |
|
Day 729 |
118 |
0.3 |
|
55.4 |
|
Day 729 |
120 |
0.3 |
|
46.5 |
|
Day 729 |
125 |
0.3 |
|
37.1 |
|
Day 729 |
130 |
0.3 |
|
55.6 |
|
Day 729 |
131 |
0.3 |
|
55.2 |
|
Day 729 |
135 |
0.3 |
|
50.2 |
|
Day 729 |
144 |
0.3 |
|
48.1 |
|
Day 729 |
145 |
0.3 |
|
50.3 |
|
Day 729 |
151 |
1.0 |
|
50.1 |
|
Day 729 |
154 |
1.0 |
|
39.9 |
|
Day 729 |
158 |
1.0 |
|
52.6 |
|
Day 729 |
162 |
1.0 |
|
37.4 |
|
Day 729 |
172 |
1.0 |
|
36 |
|
Day 729 |
180 |
1.0 |
|
43.9 |
|
Day 729 |
184 |
1.0 |
|
37.7 |
|
Day 729 |
190 |
1.0 |
|
39.5 |
|
Day 729 |
198 |
1.0 |
|
51.7 |
|
Day 729 |
219 |
3.0 |
|
41.4 |
|
Day 729 |
222 |
3.0 |
|
40 |
|
Day 729 |
224 |
3.0 |
|
31.5 |
|
Day 729 |
228 |
3.0 |
|
33.3 |
|
Day 729 |
231 |
3.0 |
|
44.1 |
|
Day 729 |
245 |
3.0 |
|
37.2 |
|
Day 729 |
247 |
3.0 |
|
42.1 |
|
Day 730 |
1 |
0 |
|
39.1 |
|
Day 730 |
14 |
0 |
|
48.4 |
|
Day 730 |
18 |
0 |
|
43.2 |
|
Day 730 |
26 |
0 |
|
38.4 |
|
Day 730 |
3 |
0 |
|
56.4 |
|
Day 730 |
37 |
0 |
|
41.9 |
|
Day 730 |
38 |
0 |
|
60.9 |
|
Day 730 |
68 |
0.1 |
|
56.3 |
|
Day 730 |
70 |
0.1 |
|
41.1 |
|
Day 730 |
77 |
0.1 |
|
38.4 |
|
Day 730 |
81 |
0.1 |
|
53.8 |
|
Day 730 |
83 |
0.1 |
|
55 |
|
Day 730 |
91 |
0.1 |
|
29.7 |
|
Day 730 |
108 |
0.3 |
|
32.4 |
|
Day 730 |
117 |
0.3 |
|
53.2 |
|
Day 730 |
119 |
0.3 |
|
46.3 |
|
Day 730 |
121 |
0.3 |
|
40.8 |
|
Day 730 |
123 |
0.3 |
|
50.4 |
|
Day 730 |
124 |
0.3 |
|
44.8 |
|
Day 730 |
143 |
0.3 |
|
48.5 |
|
Day 730 |
160 |
1.0 |
|
48.2 |
|
Day 730 |
164 |
1.0 |
|
36.8 |
|
Day 730 |
176 |
1.0 |
|
33.1 |
|
Day 730 |
191 |
1.0 |
|
42.8 |
|
Day 730 |
192 |
1.0 |
|
49.5 |
|
Day 730 |
196 |
1.0 |
|
46.5 |
|
Day 730 |
200 |
1.0 |
|
48.2 |
|
Day 730 |
210 |
3.0 |
|
40.3 |
|
Day 730 |
215 |
3.0 |
|
34.3 |
|
Day 730 |
242 |
3.0 |
|
|
|
Day 731 |
11 |
0 |
|
52.4 |
|
Day 731 |
15 |
0 |
|
36.1 |
|
Day 731 |
2 |
0 |
|
53.4 |
|
Day 731 |
31 |
0 |
|
46.4 |
|
Day 731 |
44 |
0 |
|
53.1 |
|
Day 731 |
100 |
0.1 |
|
47.1 |
|
Day 731 |
52 |
0.1 |
|
47.9 |
|
Day 731 |
55 |
0.1 |
|
51.7 |
|
Day 731 |
57 |
0.1 |
|
36.9 |
|
Day 731 |
61 |
0.1 |
|
54.1 |
|
Day 731 |
72 |
0.1 |
|
55.7 |
|
Day 731 |
74 |
0.1 |
|
52 |
|
Day 731 |
75 |
0.1 |
|
38.1 |
|
Day 731 |
82 |
0.1 |
|
58 |
|
Day 731 |
96 |
0.1 |
|
33.8 |
|
Day 731 |
104 |
0.3 |
|
47.6 |
|
Day 731 |
109 |
0.3 |
|
30.8 |
|
Day 731 |
112 |
0.3 |
|
42.3 |
|
Day 731 |
115 |
0.3 |
|
35.3 |
|
Day 731 |
126 |
0.3 |
|
34.4 |
|
Day 731 |
128 |
0.3 |
|
54.5 |
|
Day 731 |
129 |
0.3 |
|
51.6 |
|
Day 731 |
136 |
0.3 |
|
49.7 |
|
Day 731 |
140 |
0.3 |
|
43.1 |
|
Day 731 |
147 |
0.3 |
|
37.7 |
|
Day 731 |
150 |
0.3 |
|
55.8 |
|
Day 731 |
152 |
1.0 |
|
52.1 |
|
Day 731 |
153 |
1.0 |
|
50.5 |
|
Day 731 |
166 |
1.0 |
|
52.5 |
|
Day 731 |
174 |
1.0 |
|
46.2 |
|
Day 731 |
175 |
1.0 |
|
38.5 |
|
Day 731 |
185 |
1.0 |
|
52.7 |
|
Day 731 |
189 |
1.0 |
|
35.6 |
|
Day 731 |
199 |
1.0 |
|
45.3 |
|
Day 731 |
207 |
3.0 |
|
|
|
Day 731 |
216 |
3.0 |
|
44.9 |
|
Day 731 |
218 |
3.0 |
|
34.2 |
|
Day 731 |
230 |
3.0 |
|
33.9 |
|
Day 731 |
235 |
3.0 |
|
35.9 |
|
Day 734 |
17 |
0 |
|
57 |
|
Day 734 |
21 |
0 |
|
53.1 |
|
Day 734 |
23 |
0 |
|
56.1 |
|
Day 734 |
24 |
0 |
|
53.1 |
|
Day 734 |
27 |
0 |
|
36.8 |
|
Day 734 |
34 |
0 |
|
51 |
|
Day 734 |
36 |
0 |
|
43.3 |
|
Day 734 |
43 |
0 |
|
52.1 |
|
Day 734 |
5 |
0 |
|
49.4 |
|
Day 734 |
50 |
0 |
|
52.1 |
|
Day 734 |
7 |
0 |
|
46 |
|
Day 734 |
51 |
0.1 |
|
57.3 |
|
Day 734 |
53 |
0.1 |
|
47.6 |
|
Day 734 |
62 |
0.1 |
|
38.6 |
|
Day 734 |
64 |
0.1 |
|
55.6 |
|
Day 734 |
65 |
0.1 |
|
39.1 |
|
Day 734 |
67 |
0.1 |
|
52.2 |
|
Day 734 |
71 |
0.1 |
|
37.3 |
|
Day 734 |
76 |
0.1 |
|
52 |
|
Day 734 |
78 |
0.1 |
|
47.3 |
|
Day 734 |
87 |
0.1 |
|
40.4 |
|
Day 734 |
93 |
0.1 |
|
35.7 |
|
Day 734 |
94 |
0.1 |
|
40.1 |
|
Day 734 |
95 |
0.1 |
|
57 |
|
Day 734 |
98 |
0.1 |
|
52 |
|
Day 734 |
99 |
0.1 |
|
34.6 |
|
Day 734 |
101 |
0.3 |
|
40.1 |
|
Day 734 |
114 |
0.3 |
|
39.3 |
|
Day 734 |
116 |
0.3 |
|
55.7 |
|
Day 734 |
127 |
0.3 |
|
45.6 |
|
Day 734 |
132 |
0.3 |
|
53.6 |
|
Day 734 |
133 |
0.3 |
|
33.8 |
|
Day 734 |
138 |
0.3 |
|
37.7 |
|
Day 734 |
141 |
0.3 |
|
52.4 |
|
Day 734 |
146 |
0.3 |
|
45 |
|
Day 734 |
149 |
0.3 |
|
51.5 |
|
Day 734 |
161 |
1.0 |
|
44.7 |
|
Day 734 |
163 |
1.0 |
|
52.9 |
|
Day 734 |
167 |
1.0 |
|
48.2 |
|
Day 734 |
169 |
1.0 |
|
48.1 |
|
Day 734 |
170 |
1.0 |
|
39.3 |
|
Day 734 |
171 |
1.0 |
|
55.5 |
|
Day 734 |
173 |
1.0 |
|
44.6 |
|
Day 734 |
177 |
1.0 |
|
42.1 |
|
Day 734 |
179 |
1.0 |
|
51.1 |
|
Day 734 |
181 |
1.0 |
|
48 |
|
Day 734 |
182 |
1.0 |
|
49.1 |
|
Day 734 |
183 |
1.0 |
|
41.5 |
|
Day 734 |
193 |
1.0 |
|
42 |
|
Day 734 |
195 |
1.0 |
|
48.5 |
|
Day 734 |
205 |
3.0 |
|
33.1 |
|
Day 734 |
217 |
3.0 |
|
37.2 |
|
Day 734 |
220 |
3.0 |
|
36.1 |
|
Day 734 |
223 |
3.0 |
|
40.6 |
|
Day 734 |
246 |
3.0 |
|
40.5 |
|
Abbreviations: |
NA: Not Available
|