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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Salicylazosulfapyridine |
CASRN: | ="599-79-1" |
Study Number: | C61552B |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | GAVAGE |
TDMS Number: | 0509908 |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (MG/KG) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 6 |
185 |
2700 |
|
19.2 |
|
Day 7 |
194 |
2700 |
|
20.1 |
|
Day 75 |
78 |
675 |
|
|
|
Day 150 |
12 |
0 |
|
|
|
Day 151 |
292 |
0 |
|
|
|
Day 288 |
83 |
675 |
|
29.4 |
|
Day 351 |
33 |
0 |
|
|
|
Day 402 |
168 |
1350 |
|
|
|
Day 420 |
2 |
0 |
|
41.7 |
|
Day 420 |
5 |
0 |
|
|
|
Day 456 |
290 |
0 |
|
46.9 |
|
Day 456 |
291 |
0 |
|
53.1 |
|
Day 456 |
293 |
0 |
|
46.4 |
|
Day 456 |
294 |
0 |
|
46.6 |
|
Day 456 |
295 |
0 |
|
44.6 |
|
Day 456 |
296 |
0 |
|
51.2 |
|
Day 456 |
297 |
0 |
|
38.1 |
|
Day 456 |
298 |
0 |
|
40 |
|
Day 456 |
299 |
0 |
|
46.6 |
|
Day 456 |
300 |
0 |
|
43.4 |
|
Day 456 |
51 |
0 |
|
55.3 |
|
Day 456 |
52 |
0 |
|
53.6 |
|
Day 456 |
53 |
0 |
|
60.1 |
|
Day 456 |
54 |
0 |
|
59.8 |
|
Day 456 |
55 |
0 |
|
54.2 |
|
Day 456 |
56 |
0 |
|
49.4 |
|
Day 456 |
57 |
0 |
|
52.4 |
|
Day 456 |
58 |
0 |
|
51.3 |
|
Day 456 |
59 |
0 |
|
52.4 |
|
Day 456 |
60 |
0 |
|
50.6 |
|
Day 456 |
111 |
675 |
|
54.9 |
|
Day 456 |
112 |
675 |
|
48.7 |
|
Day 456 |
113 |
675 |
|
57.2 |
|
Day 456 |
114 |
675 |
|
45.2 |
|
Day 456 |
115 |
675 |
|
50.1 |
|
Day 456 |
116 |
675 |
|
53.3 |
|
Day 456 |
117 |
675 |
|
58.6 |
|
Day 456 |
118 |
675 |
|
47.6 |
|
Day 456 |
119 |
675 |
|
54.8 |
|
Day 456 |
120 |
675 |
|
57.4 |
|
Day 456 |
171 |
1350 |
|
45.7 |
|
Day 456 |
172 |
1350 |
|
58.3 |
|
Day 456 |
173 |
1350 |
|
56.8 |
|
Day 456 |
174 |
1350 |
|
54.4 |
|
Day 456 |
175 |
1350 |
|
50.8 |
|
Day 456 |
176 |
1350 |
|
55.8 |
|
Day 456 |
177 |
1350 |
|
53.6 |
|
Day 456 |
178 |
1350 |
|
51.6 |
|
Day 456 |
179 |
1350 |
|
57.9 |
|
Day 456 |
180 |
1350 |
|
62.7 |
|
Day 456 |
231 |
2700 |
|
45.8 |
|
Day 456 |
232 |
2700 |
|
37.3 |
|
Day 456 |
233 |
2700 |
|
40 |
|
Day 456 |
234 |
2700 |
|
44.4 |
|
Day 456 |
235 |
2700 |
|
45.7 |
|
Day 456 |
236 |
2700 |
|
44 |
|
Day 456 |
237 |
2700 |
|
44.7 |
|
Day 456 |
238 |
2700 |
|
45.5 |
|
Day 456 |
239 |
2700 |
|
51.3 |
|
Day 456 |
240 |
2700 |
|
49.8 |
|
Day 497 |
223 |
2700 |
|
40.2 |
|
Day 504 |
127 |
1350 |
|
|
|
Day 505 |
149 |
1350 |
|
|
|
Day 567 |
105 |
675 |
|
|
|
Day 574 |
289 |
0 |
|
41.1 |
|
Day 588 |
89 |
675 |
|
27.5 |
|
Day 601 |
261 |
0 |
|
39.4 |
|
Day 610 |
17 |
0 |
|
28.9 |
|
Day 610 |
281 |
0 |
|
26.4 |
|
Day 611 |
30 |
0 |
|
24.4 |
|
Day 611 |
90 |
675 |
|
42 |
|
Day 611 |
157 |
1350 |
|
34.1 |
|
Day 633 |
285 |
0 |
|
|
|
Day 647 |
215 |
2700 |
|
29.4 |
|
Day 648 |
139 |
1350 |
|
|
|
Day 652 |
64 |
675 |
|
|
|
Day 658 |
44 |
0 |
|
25.4 |
|
Day 662 |
8 |
0 |
|
|
|
Day 665 |
82 |
675 |
|
|
|
Day 666 |
13 |
0 |
|
34.6 |
|
Day 666 |
61 |
675 |
|
|
|
Day 678 |
124 |
1350 |
|
34 |
|
Day 681 |
132 |
1350 |
|
|
|
Day 681 |
155 |
1350 |
|
35.8 |
|
Day 689 |
28 |
0 |
|
|
|
Day 700 |
76 |
675 |
|
28 |
|
Day 702 |
128 |
1350 |
|
|
|
Day 728 |
15 |
0 |
|
53.3 |
|
Day 728 |
19 |
0 |
|
47 |
|
Day 728 |
22 |
0 |
|
38.5 |
|
Day 728 |
241 |
0 |
|
51.4 |
|
Day 728 |
242 |
0 |
|
26.8 |
|
Day 728 |
243 |
0 |
|
48.6 |
|
Day 728 |
244 |
0 |
|
34.6 |
|
Day 728 |
245 |
0 |
|
52.3 |
|
Day 728 |
246 |
0 |
|
37.3 |
|
Day 728 |
249 |
0 |
|
53.5 |
|
Day 728 |
253 |
0 |
|
49.3 |
|
Day 728 |
258 |
0 |
|
49.2 |
|
Day 728 |
26 |
0 |
|
48.9 |
|
Day 728 |
264 |
0 |
|
44.8 |
|
Day 728 |
273 |
0 |
|
42.2 |
|
Day 728 |
274 |
0 |
|
51.3 |
|
Day 728 |
282 |
0 |
|
53.8 |
|
Day 728 |
288 |
0 |
|
30.7 |
|
Day 728 |
32 |
0 |
|
23.6 |
|
Day 728 |
35 |
0 |
|
57.2 |
|
Day 728 |
4 |
0 |
|
43.9 |
|
Day 728 |
40 |
0 |
|
54.7 |
|
Day 728 |
45 |
0 |
|
56.3 |
|
Day 728 |
9 |
0 |
|
49 |
|
Day 728 |
100 |
675 |
|
51.3 |
|
Day 728 |
106 |
675 |
|
46.3 |
|
Day 728 |
65 |
675 |
|
65.2 |
|
Day 728 |
71 |
675 |
|
54.1 |
|
Day 728 |
74 |
675 |
|
67.5 |
|
Day 728 |
79 |
675 |
|
61.2 |
|
Day 728 |
84 |
675 |
|
36.7 |
|
Day 728 |
88 |
675 |
|
55.9 |
|
Day 728 |
91 |
675 |
|
58.3 |
|
Day 728 |
95 |
675 |
|
59.9 |
|
Day 728 |
123 |
1350 |
|
48.5 |
|
Day 728 |
129 |
1350 |
|
52.6 |
|
Day 728 |
133 |
1350 |
|
36.2 |
|
Day 728 |
136 |
1350 |
|
51.9 |
|
Day 728 |
140 |
1350 |
|
61.2 |
|
Day 728 |
144 |
1350 |
|
57.5 |
|
Day 728 |
148 |
1350 |
|
46 |
|
Day 728 |
153 |
1350 |
|
63.2 |
|
Day 728 |
161 |
1350 |
|
53.5 |
|
Day 728 |
166 |
1350 |
|
59.1 |
|
Day 728 |
184 |
2700 |
|
50.4 |
|
Day 728 |
189 |
2700 |
|
51.1 |
|
Day 728 |
193 |
2700 |
|
56.3 |
|
Day 728 |
198 |
2700 |
|
52.8 |
|
Day 728 |
202 |
2700 |
|
52.8 |
|
Day 728 |
207 |
2700 |
|
47.4 |
|
Day 728 |
216 |
2700 |
|
57.5 |
|
Day 728 |
220 |
2700 |
|
52.8 |
|
Day 728 |
224 |
2700 |
|
40.6 |
|
Day 728 |
230 |
2700 |
|
49.1 |
|
Day 730 |
1 |
0 |
|
46.7 |
|
Day 730 |
10 |
0 |
|
55.4 |
|
Day 730 |
11 |
0 |
|
46.5 |
|
Day 730 |
14 |
0 |
|
55.3 |
|
Day 730 |
16 |
0 |
|
31.9 |
|
Day 730 |
18 |
0 |
|
59.7 |
|
Day 730 |
20 |
0 |
|
53.3 |
|
Day 730 |
21 |
0 |
|
55.2 |
|
Day 730 |
23 |
0 |
|
55.3 |
|
Day 730 |
24 |
0 |
|
32 |
|
Day 730 |
247 |
0 |
|
48.9 |
|
Day 730 |
248 |
0 |
|
42.6 |
|
Day 730 |
25 |
0 |
|
58.3 |
|
Day 730 |
250 |
0 |
|
48.1 |
|
Day 730 |
251 |
0 |
|
48.4 |
|
Day 730 |
252 |
0 |
|
34 |
|
Day 730 |
254 |
0 |
|
49.8 |
|
Day 730 |
255 |
0 |
|
52.4 |
|
Day 730 |
256 |
0 |
|
46.8 |
|
Day 730 |
257 |
0 |
|
33.6 |
|
Day 730 |
259 |
0 |
|
51.8 |
|
Day 730 |
260 |
0 |
|
51.7 |
|
Day 730 |
262 |
0 |
|
53.7 |
|
Day 730 |
263 |
0 |
|
50.5 |
|
Day 730 |
265 |
0 |
|
50.1 |
|
Day 730 |
266 |
0 |
|
50.6 |
|
Day 730 |
267 |
0 |
|
45.2 |
|
Day 730 |
268 |
0 |
|
48.4 |
|
Day 730 |
269 |
0 |
|
50.9 |
|
Day 730 |
27 |
0 |
|
57.5 |
|
Day 730 |
270 |
0 |
|
41.2 |
|
Day 730 |
271 |
0 |
|
51.2 |
|
Day 730 |
272 |
0 |
|
51 |
|
Day 730 |
275 |
0 |
|
51.2 |
|
Day 730 |
276 |
0 |
|
37 |
|
Day 730 |
277 |
0 |
|
30.1 |
|
Day 730 |
278 |
0 |
|
49 |
|
Day 730 |
279 |
0 |
|
37.8 |
|
Day 730 |
280 |
0 |
|
47.8 |
|
Day 730 |
283 |
0 |
|
41.8 |
|
Day 730 |
284 |
0 |
|
42.1 |
|
Day 730 |
286 |
0 |
|
44.7 |
|
Day 730 |
287 |
0 |
|
40.7 |
|
Day 730 |
29 |
0 |
|
42.6 |
|
Day 730 |
3 |
0 |
|
53.6 |
|
Day 730 |
31 |
0 |
|
58.1 |
|
Day 730 |
34 |
0 |
|
42.3 |
|
Day 730 |
36 |
0 |
|
52.6 |
|
Day 730 |
37 |
0 |
|
54.2 |
|
Day 730 |
38 |
0 |
|
47.6 |
|
Day 730 |
39 |
0 |
|
49.2 |
|
Day 730 |
41 |
0 |
|
61.4 |
|
Day 730 |
42 |
0 |
|
40 |
|
Day 730 |
43 |
0 |
|
55 |
|
Day 730 |
6 |
0 |
|
50.9 |
|
Day 730 |
7 |
0 |
|
48.1 |
|
Day 731 |
46 |
0 |
|
48.1 |
|
Day 731 |
47 |
0 |
|
55.8 |
|
Day 731 |
48 |
0 |
|
61.2 |
|
Day 731 |
49 |
0 |
|
47 |
|
Day 731 |
50 |
0 |
|
49.6 |
|
Day 731 |
121 |
1350 |
|
64.4 |
|
Day 731 |
122 |
1350 |
|
60.3 |
|
Day 731 |
125 |
1350 |
|
50.5 |
|
Day 731 |
126 |
1350 |
|
43.3 |
|
Day 731 |
130 |
1350 |
|
56.4 |
|
Day 731 |
131 |
1350 |
|
52.3 |
|
Day 731 |
134 |
1350 |
|
38.7 |
|
Day 731 |
135 |
1350 |
|
57.9 |
|
Day 731 |
137 |
1350 |
|
59.5 |
|
Day 731 |
138 |
1350 |
|
35.9 |
|
Day 731 |
141 |
1350 |
|
61.7 |
|
Day 731 |
142 |
1350 |
|
56.1 |
|
Day 731 |
143 |
1350 |
|
49.1 |
|
Day 731 |
145 |
1350 |
|
51.9 |
|
Day 731 |
146 |
1350 |
|
62 |
|
Day 731 |
147 |
1350 |
|
55.9 |
|
Day 731 |
150 |
1350 |
|
55.3 |
|
Day 731 |
151 |
1350 |
|
63.2 |
|
Day 731 |
181 |
2700 |
|
48.7 |
|
Day 731 |
182 |
2700 |
|
44.8 |
|
Day 731 |
183 |
2700 |
|
48 |
|
Day 731 |
186 |
2700 |
|
50.3 |
|
Day 731 |
187 |
2700 |
|
48.4 |
|
Day 731 |
188 |
2700 |
|
38.1 |
|
Day 731 |
190 |
2700 |
|
51.8 |
|
Day 731 |
191 |
2700 |
|
44.9 |
|
Day 731 |
192 |
2700 |
|
43 |
|
Day 731 |
195 |
2700 |
|
46.6 |
|
Day 731 |
196 |
2700 |
|
47.3 |
|
Day 731 |
197 |
2700 |
|
53.5 |
|
Day 731 |
199 |
2700 |
|
43.4 |
|
Day 731 |
200 |
2700 |
|
40.1 |
|
Day 731 |
201 |
2700 |
|
54.5 |
|
Day 731 |
203 |
2700 |
|
60.5 |
|
Day 731 |
204 |
2700 |
|
41.5 |
|
Day 731 |
205 |
2700 |
|
44.5 |
|
Day 731 |
206 |
2700 |
|
45.5 |
|
Day 731 |
208 |
2700 |
|
50.3 |
|
Day 731 |
209 |
2700 |
|
43.6 |
|
Day 731 |
210 |
2700 |
|
52.7 |
|
Day 731 |
211 |
2700 |
|
40.1 |
|
Day 731 |
212 |
2700 |
|
51.3 |
|
Day 731 |
213 |
2700 |
|
48.9 |
|
Day 731 |
214 |
2700 |
|
45.4 |
|
Day 731 |
225 |
2700 |
|
47.5 |
|
Day 731 |
226 |
2700 |
|
41.1 |
|
Day 731 |
227 |
2700 |
|
52.1 |
|
Day 731 |
228 |
2700 |
|
47 |
|
Day 731 |
229 |
2700 |
|
54.6 |
|
Day 732 |
101 |
675 |
|
61 |
|
Day 732 |
102 |
675 |
|
53.2 |
|
Day 732 |
103 |
675 |
|
55.2 |
|
Day 732 |
104 |
675 |
|
60.1 |
|
Day 732 |
107 |
675 |
|
67.4 |
|
Day 732 |
108 |
675 |
|
55.1 |
|
Day 732 |
109 |
675 |
|
32.9 |
|
Day 732 |
110 |
675 |
|
54.2 |
|
Day 732 |
62 |
675 |
|
53.8 |
|
Day 732 |
63 |
675 |
|
61.4 |
|
Day 732 |
66 |
675 |
|
56.5 |
|
Day 732 |
67 |
675 |
|
54.5 |
|
Day 732 |
68 |
675 |
|
59.9 |
|
Day 732 |
69 |
675 |
|
64.9 |
|
Day 732 |
70 |
675 |
|
64.6 |
|
Day 732 |
72 |
675 |
|
59.1 |
|
Day 732 |
73 |
675 |
|
49.5 |
|
Day 732 |
75 |
675 |
|
43.5 |
|
Day 732 |
77 |
675 |
|
61.7 |
|
Day 732 |
80 |
675 |
|
57.1 |
|
Day 732 |
81 |
675 |
|
59.6 |
|
Day 732 |
85 |
675 |
|
65 |
|
Day 732 |
86 |
675 |
|
52.4 |
|
Day 732 |
87 |
675 |
|
42.5 |
|
Day 732 |
92 |
675 |
|
53.7 |
|
Day 732 |
93 |
675 |
|
58.5 |
|
Day 732 |
94 |
675 |
|
60.9 |
|
Day 732 |
96 |
675 |
|
64.4 |
|
Day 732 |
97 |
675 |
|
55.8 |
|
Day 732 |
98 |
675 |
|
58.1 |
|
Day 732 |
99 |
675 |
|
60.2 |
|
Day 732 |
152 |
1350 |
|
69.3 |
|
Day 732 |
154 |
1350 |
|
45.9 |
|
Day 732 |
156 |
1350 |
|
55.4 |
|
Day 732 |
158 |
1350 |
|
40.9 |
|
Day 732 |
159 |
1350 |
|
54.4 |
|
Day 732 |
160 |
1350 |
|
46.7 |
|
Day 732 |
162 |
1350 |
|
59.5 |
|
Day 732 |
163 |
1350 |
|
54.2 |
|
Day 732 |
164 |
1350 |
|
60.8 |
|
Day 732 |
165 |
1350 |
|
56.8 |
|
Day 732 |
167 |
1350 |
|
45.4 |
|
Day 732 |
169 |
1350 |
|
45.9 |
|
Day 732 |
170 |
1350 |
|
48.5 |
|
Day 732 |
217 |
2700 |
|
46.1 |
|
Day 732 |
218 |
2700 |
|
46 |
|
Day 732 |
219 |
2700 |
|
61.8 |
|
Day 732 |
221 |
2700 |
|
52.8 |
|
Day 732 |
222 |
2700 |
|
50.9 |
|
Abbreviations: |
NA: Not Available
|