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Chemical Name: | Water Disinfection Byproducts (Sodium Chlorate) |
---|---|
CASRN: | ="7775-09-9" |
Study Number: | C96010A |
Study Length (Year Completed): | 3 Weeks (N/A) |
Exposure Route: | WATER |
TDMS Number: | 9601002.ss |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Hematology Individual Animal Data | ||||||||||||||||||
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Measurement Time | Animal Number | Dose Group (mg/L) | Control Code | Erythrcyt (million/uL) | Hgb (g/dL) | HCT (Automated) (%) | MCV (fL) | MCH (pg) | MCHC (g/dL) | Retics (million/uL) | Platelet (1000/mL) | Leukocytes (1000/mL) | Neut (1000/mL) | Lymph (1000/mL) | Mono (1000/mL) | EOS (1000/mL) | Basophils (1000/mL) | LUC (1000/mL) |
Day 22 | 0001 | 0 | V | 10.69 | 16.7 | 49.5 | 46.3 | 15.6 | 33.7 | 3.3 | 1175 | 3.63 | 0.29 | 3.22 | 0.06 | 0.04 | 0.00 | 0.01 |
Day 22 | 0002 | 0 | V | 12.34 | 19.5 | 57.8 | 46.9 | 15.8 | 33.6 | 3.3 | 818 | 4.40 | 0.35 | 3.94 | 0.05 | 0.04 | 0.01 | 0.01 |
Day 22 | 0003 | 0 | V | 10.93 | 17.0 | 51.4 | 47.1 | 15.6 | 33.1 | 3.2 | 1119 | 7.30 | 0.50 | 6.66 | 0.06 | 0.06 | 0.01 | 0.02 |
Day 22 | 0004 | 0 | V | 10.95 | 17.0 | 51.8 | 47.3 | 15.5 | 32.8 | 3.2 | 1252 | 6.01 | 0.44 | 5.39 | 0.07 | 0.08 | 0.01 | 0.02 |
Day 22 | 0005 | 0 | V | 10.13 | 16.4 | 48.8 | 48.1 | 16.2 | 33.7 | 3.3 | 1437 | 5.73 | 0.96 | 4.67 | 0.07 | 0.03 | 0.00 | 0.01 |
Day 22 | 0006 | 0 | V | 10.20 | 16.2 | 48.4 | 47.5 | 15.9 | 33.4 | 3.2 | 1393 | 5.54 | 0.49 | 4.92 | 0.07 | 0.03 | 0.00 | 0.02 |
Day 22 | 0007 | 0 | V | 9.78 | 15.5 | 46.1 | 47.2 | 15.9 | 33.6 | 3.2 | 1078 | 6.00 | 1.14 | 4.71 | 0.09 | 0.04 | 0.00 | 0.01 |
Day 22 | 0008 | 0 | V | 9.79 | 15.1 | 46.2 | 47.1 | 15.5 | 32.8 | 3.3 | 1252 | 5.66 | 1.07 | 4.48 | 0.07 | 0.02 | 0.00 | 0.02 |
Day 22 | 0009 | 0 | V | 9.92 | 15.9 | 48.4 | 48.8 | 16.0 | 32.8 | 3.2 | 1307 | 4.81 | 0.49 | 4.18 | 0.09 | 0.04 | 0.00 | 0.01 |
Day 22 | 0010 | 0 | V | 9.85 | 16.1 | 47.7 | 48.4 | 16.3 | 33.7 | 3.5 | 1214 | 4.74 | 0.36 | 4.21 | 0.10 | 0.05 | 0.00 | 0.01 |
Day 22 | 0011 | 125 | 10.22 | 16.2 | 48.4 | 47.3 | 15.9 | 33.6 | 3.5 | 1256 | 2.35 | 0.24 | 2.03 | 0.04 | 0.04 | 0.00 | 0.01 | |
Day 22 | 0012 | 125 | 10.61 | 16.7 | 50.1 | 47.2 | 15.7 | 33.2 | 3.6 | 984 | 4.72 | 0.58 | 4.04 | 0.07 | 0.03 | 0.00 | 0.01 | |
Day 22 | 0013 | 125 | 10.31 | 16.0 | 48.5 | 47.0 | 15.5 | 33.1 | 3.3 | 1009 | 4.08 | 0.27 | 3.75 | 0.04 | 0.02 | 0.00 | 0.01 | |
Day 22 | 0014 | 125 | 10.51 | 16.2 | 49.7 | 47.2 | 15.4 | 32.6 | 3.7 | 1256 | 3.47 | 0.32 | 3.06 | 0.05 | 0.02 | 0.00 | 0.01 | |
Day 22 | 0015 | 125 | 10.24 | 16.1 | 48.8 | 47.7 | 15.7 | 32.9 | 3.1 | 1293 | 5.43 | 0.77 | 4.54 | 0.07 | 0.03 | 0.00 | 0.01 | |
Day 22 | 0016 | 125 | 9.56 | 15.2 | 45.2 | 47.3 | 15.9 | 33.6 | 3.1 | 1093 | 5.32 | 0.53 | 4.66 | 0.06 | 0.05 | 0.00 | 0.01 | |
Day 22 | 0017 | 125 | 10.01 | 16.0 | 47.4 | 47.3 | 15.9 | 33.7 | 3.2 | 1248 | 6.69 | 1.20 | 5.36 | 0.07 | 0.04 | 0.00 | 0.01 | |
Day 22 | 0018 | 125 | 9.54 | 15.3 | 45.8 | 48.0 | 16.1 | 33.5 | 3.2 | 1244 | 6.28 | 0.59 | 5.48 | 0.12 | 0.06 | 0.00 | 0.02 | |
Day 22 | 0019 | 125 | 10.30 | 16.4 | 48.6 | 47.2 | 15.9 | 33.7 | 3.9 | 1311 | 5.86 | 0.67 | 4.97 | 0.10 | 0.10 | 0.00 | 0.03 | |
Day 22 | 0020 | 125 | 10.25 | 16.0 | 47.2 | 46.0 | 15.6 | 33.8 | 3.5 | 1132 | 6.16 | 0.62 | 5.26 | 0.12 | 0.15 | 0.00 | 0.01 | |
Day 22 | 0021 | 250 | 10.53 | 16.3 | 49.5 | 47.0 | 15.5 | 33.0 | 3.5 | 1116 | 2.59 | 0.19 | 2.33 | 0.04 | 0.03 | 0.00 | 0.01 | |
Day 22 | 0022 | 250 | 10.17 | 16.4 | 48.4 | 47.6 | 16.2 | 34.0 | 3.1 | 1074 | 2.94 | 0.17 | 2.68 | 0.06 | 0.03 | 0.01 | 0 | |
Day 22 | 0023 | 250 | 9.90 | 15.8 | 47.4 | 47.9 | 16.0 | 33.4 | 3.4 | 1074 | 4.34 | 0.31 | 3.96 | 0.05 | 0.02 | 0.00 | 0.01 | |
Day 22 | 0024 | 250 | 9.89 | 15.5 | 47.2 | 47.7 | 15.6 | 32.8 | 3.5 | 1274 | 4.41 | 0.47 | 3.81 | 0.09 | 0.02 | 0.01 | 0.01 | |
Day 22 | 0025 | 250 | 9.57 | 14.7 | 45.4 | 47.4 | 15.4 | 32.5 | 3.3 | 1093 | 5.61 | 0.84 | 4.62 | 0.08 | 0.06 | 0.00 | 0.01 | |
Day 22 | 0026 | 250 | 10.10 | 15.7 | 47.3 | 46.8 | 15.5 | 33.1 | 3.4 | 1263 | 7.84 | 0.74 | 6.92 | 0.11 | 0.06 | 0.00 | 0.01 | |
Day 22 | 0027 | 250 | 10.59 | 16.6 | 50.2 | 47.4 | 15.7 | 33.2 | 3.5 | 1405 | 5.97 | 0.65 | 5.17 | 0.09 | 0.05 | 0.00 | 0.01 | |
Day 22 | 0028 | 250 | 10.01 | 15.6 | 46.9 | 46.9 | 15.6 | 33.2 | 3.7 | 1315 | 6.75 | 0.60 | 5.99 | 0.09 | 0.07 | 0.00 | 0.01 | |
Day 22 | 0029 | 250 | 10.49 | 16.3 | 49.8 | 47.5 | 15.6 | 32.8 | 3.8 | 1379 | 6.35 | 0.61 | 5.52 | 0.11 | 0.09 | 0.01 | 0.01 | |
Day 22 | 0030 | 250 | 9.65 | 15.6 | 45.3 | 47.0 | 16.2 | 34.4 | 3.9 | 1247 | 7.26 | 0.69 | 6.38 | 0.10 | 0.06 | 0.01 | 0.03 | |
Day 22 | 0031 | 500 | 10.54 | 16.6 | 48.4 | 46.0 | 15.8 | 34.3 | 3.4 | 1035 | 5.09 | 0.37 | 4.55 | 0.07 | 0.09 | 0.00 | 0.01 | |
Day 22 | 0032 | 500 | 11.12 | 17.1 | 52.8 | 47.5 | 15.4 | 32.4 | 3.2 | 1042 | 1.81 | 0.09 | 1.67 | 0.03 | 0.02 | 0.00 | 0 | |
Day 22 | 0033 | 500 | 10.51 | 16.3 | 48.5 | 46.1 | 15.5 | 33.6 | 2.9 | 919 | 3.04 | 0.26 | 2.69 | 0.06 | 0.02 | 0.01 | 0.01 | |
Day 22 | 0034 | 500 | 10.60 | 16.6 | 49.9 | 47.1 | 15.6 | 33.2 | 3.6 | 1364 | 6.00 | 0.71 | 5.15 | 0.09 | 0.04 | 0.00 | 0.01 | |
Day 22 | 0035 | 500 | 10.88 | 16.4 | 50.7 | 46.6 | 15.1 | 32.4 | 3.6 | 1370 | 5.78 | 1.70 | 3.95 | 0.07 | 0.05 | 0.01 | 0.01 | |
Day 22 | 0036 | 500 | 10.57 | 16.5 | 48.3 | 45.7 | 15.7 | 34.3 | 3.6 | 1163 | 4.22 | 0.38 | 3.72 | 0.08 | 0.03 | 0.00 | 0 | |
Day 22 | 0037 | 500 | 9.90 | 15.3 | 47.2 | 47.7 | 15.4 | 32.4 | 3.2 | 1242 | 6.72 | 0.66 | 5.89 | 0.09 | 0.05 | 0.01 | 0.02 | |
Day 22 | 0038 | 500 | 10.23 | 16.0 | 49.2 | 48.1 | 15.6 | 32.4 | 3.5 | 1263 | 6.08 | 0.57 | 5.40 | 0.08 | 0.02 | 0.00 | 0.01 | |
Day 22 | 0039 | 500 | 10.30 | 16.2 | 48.5 | 47.0 | 15.7 | 33.4 | 3.8 | 1348 | 6.95 | 0.54 | 6.19 | 0.10 | 0.08 | 0.01 | 0.03 | |
Day 22 | 0040 | 500 | 9.70 | 15.8 | 45.8 | 47.2 | 16.3 | 34.5 | 3.4 | 1228 | 7.89 | 0.97 | 6.73 | 0.11 | 0.07 | 0.01 | 0.01 | |
Day 22 | 0041 | 1000 | 10.75 | 16.8 | 51.2 | 47.6 | 15.6 | 32.7 | 3.4 | 986 | 4.05 | 0.23 | 3.75 | 0.05 | 0.02 | 0.00 | 0.01 | |
Day 22 | 0042 | 1000 | 11.60 | 18.3 | 54.4 | 46.9 | 15.8 | 33.7 | 3.5 | 972 | 5.05 | 0.35 | 4.60 | 0.07 | 0.02 | 0.00 | 0 | |
Day 22 | 0043 | 1000 | 10.04 | 15.7 | 47.4 | 47.2 | 15.7 | 33.1 | 3.4 | 947 | 4.01 | 0.26 | 3.67 | 0.05 | 0.02 | 0.00 | 0.01 | |
Day 22 | 0044 | 1000 | 10.68 | 16.3 | 51.1 | 47.9 | 15.2 | 31.8 | 3.4 | 1302 | 4.87 | 0.39 | 4.41 | 0.05 | 0.01 | 0.00 | 0.01 | |
Day 22 | 0045 | 1000 | 9.83 | 15.3 | 46.2 | 47.0 | 15.5 | 33.1 | 2.9 | 1182 | 4.14 | 0.48 | 3.58 | 0.05 | 0.02 | 0.00 | 0.01 | |
Day 22 | 0046 | 1000 | 10.31 | 15.8 | 49.2 | 47.7 | 15.4 | 32.2 | 3.8 | 1340 | 6.70 | 0.71 | 5.88 | 0.07 | 0.03 | 0.00 | 0.01 | |
Day 22 | 0047 | 1000 | 10.04 | 15.7 | 47.8 | 47.6 | 15.6 | 32.8 | 3.3 | 1309 | 5.22 | 0.50 | 4.64 | 0.03 | 0.02 | 0.00 | 0.02 | |
Day 22 | 0048 | 1000 | 9.94 | 15.4 | 47.1 | 47.4 | 15.5 | 32.7 | 3.5 | 1269 | 5.52 | 0.45 | 4.96 | 0.06 | 0.03 | 0.00 | 0.02 | |
Day 22 | 0049 | 1000 | 10.13 | 15.9 | 49.1 | 48.5 | 15.7 | 32.4 | 3.2 | 1393 | 6.25 | 0.47 | 5.65 | 0.07 | 0.03 | 0.00 | 0.02 | |
Day 22 | 0050 | 1000 | 10.43 | 16.1 | 48.3 | 46.3 | 15.5 | 33.4 | 3.9 | 1285 | 5.38 | 0.59 | 4.58 | 0.15 | 0.05 | 0.00 | 0.01 | |
Day 22 | 0051 | 2000 | 9.82 | 15.9 | 47.7 | 48.5 | 16.2 | 33.3 | 3.4 | 1274 | 4.79 | 0.44 | 4.25 | 0.06 | 0.03 | 0.00 | 0.01 | |
Day 22 | 0052 | 2000 | 10.55 | 16.6 | 50.7 | 48.1 | 15.7 | 32.7 | 3.6 | 1224 | 4.81 | 0.29 | 4.42 | 0.03 | 0.04 | 0.01 | 0.01 | |
Day 22 | 0053 | 2000 | 10.60 | 16.5 | 51.1 | 48.2 | 15.6 | 32.3 | 3.6 | 1105 | 2.08 | 0.29 | 1.73 | 0.04 | 0.02 | 0.00 | 0 | |
Day 22 | 0054 | 2000 | 10.05 | 15.3 | 48.8 | 48.5 | 15.2 | 31.4 | 3.3 | 1382 | 2.48 | 0.20 | 2.23 | 0.03 | 0.01 | 0.00 | 0 | |
Day 22 | 0055 | 2000 | 10.28 | 15.7 | 49.5 | 48.2 | 15.3 | 31.7 | 3.4 | 1028 | 2.69 | 0.26 | 2.36 | 0.05 | 0.01 | 0.00 | 0.01 | |
Day 22 | 0056 | 2000 | 10.10 | 15.7 | 48.5 | 48.0 | 15.6 | 32.5 | 3.3 | 1244 | 3.29 | 0.23 | 3.02 | 0.03 | 0.00 | 0.00 | 0.01 | |
Day 22 | 0057 | 2000 | 10.05 | 15.6 | 48.2 | 48.0 | 15.6 | 32.4 | 3.1 | 1406 | 5.50 | 0.55 | 4.87 | 0.07 | 0.01 | 0.00 | 0.01 | |
Day 22 | 0058 | 2000 | 10.05 | 15.5 | 47.8 | 47.6 | 15.5 | 32.5 | 3.4 | 1292 | 6.26 | 0.63 | 5.50 | 0.08 | 0.03 | 0.00 | 0.02 | |
Day 22 | 0059 | 2000 | 10.51 | 16.3 | 50.4 | 48.0 | 15.6 | 32.4 | 3.5 | 1484 | 5.78 | 0.50 | 5.20 | 0.05 | 0.01 | 0.00 | 0.01 | |
Day 22 | 0060 | 2000 | 10.05 | 16.2 | 47.9 | 47.6 | 16.1 | 33.9 | 3.7 | 1291 | 6.20 | 0.64 | 5.35 | 0.11 | 0.07 | 0.01 | 0.02 | |
Abbreviations: | ||||||||||||||||||
NA: Not Available, V: Vehicle Control, Erythrcyt: Red Blood Cell Count, Hgb: Hemoglobin, HCT (Automated): Hematocrit, MCV: Mean Corpuscular Volume, MCH: Mean Cell Hemoglobin, MCHC: Mean Cell Hemoglobin Concentration, Retics: Reticulocyte Count, Platelet: Platelet Count, Leukocytes: White Blood Cell Count, Neut: Neutrophil Count, Lymph: Lymphocyte Count, Mono: Monocyte Count, EOS: Eosinophil Count, Basophils: Basophil Count, LUC: Large Unstained Cells Count |