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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Succinic anhydride |
CASRN: | ="108-30-5" |
Study Number: | C55696A |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | GAVAGE |
TDMS Number: | 0504101 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group () |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 2 |
242 |
50 |
|
116 |
|
Day 2 |
258 |
50 |
|
114 |
|
Day 5 |
245 |
50 |
|
130 |
|
Day 5 |
326 |
100 |
|
127 |
|
Day 5 |
360 |
100 |
|
112 |
|
Day 9 |
233 |
0 |
|
110 |
|
Day 9 |
246 |
50 |
|
95 |
|
Day 9 |
247 |
50 |
|
80 |
|
Day 9 |
300 |
50 |
|
79 |
|
Day 9 |
313 |
100 |
|
121 |
|
Day 9 |
329 |
100 |
|
|
|
Day 10 |
248 |
50 |
|
148.2 |
|
Day 11 |
285 |
50 |
|
100 |
|
Day 12 |
253 |
50 |
|
130 |
|
Day 13 |
249 |
50 |
|
147 |
|
Day 77 |
224 |
0 |
|
108 |
|
Day 111 |
328 |
100 |
|
186 |
|
Day 159 |
390 |
0 |
|
189 |
|
Day 169 |
193 |
0 |
|
205 |
|
Day 169 |
259 |
50 |
|
179 |
|
Day 170 |
322 |
100 |
|
218 |
|
Day 176 |
323 |
100 |
|
205 |
|
Day 180 |
376 |
0 |
|
|
|
Day 180 |
377 |
0 |
|
|
|
Day 180 |
378 |
0 |
|
|
|
Day 180 |
379 |
0 |
|
|
|
Day 180 |
380 |
0 |
|
|
|
Day 187 |
294 |
50 |
|
196 |
|
Day 198 |
320 |
100 |
|
217 |
|
Day 200 |
348 |
100 |
|
195 |
|
Day 225 |
306 |
100 |
|
151 |
|
Day 283 |
341 |
100 |
|
234.6 |
|
Day 337 |
325 |
100 |
|
218.9 |
|
Day 353 |
319 |
100 |
|
223.4 |
|
Day 360 |
386 |
0 |
|
|
|
Day 360 |
387 |
0 |
|
|
|
Day 360 |
388 |
0 |
|
|
|
Day 360 |
389 |
0 |
|
|
|
Day 365 |
321 |
100 |
|
164.5 |
|
Day 401 |
244 |
50 |
|
219.6 |
|
Day 417 |
356 |
100 |
|
265.5 |
|
Day 471 |
280 |
50 |
|
163.1 |
|
Day 479 |
235 |
0 |
|
249.9 |
|
Day 494 |
228 |
0 |
|
293.6 |
|
Day 503 |
331 |
100 |
|
207.6 |
|
Day 507 |
187 |
0 |
|
292.4 |
|
Day 516 |
192 |
0 |
|
263.1 |
|
Day 541 |
271 |
50 |
|
253.7 |
|
Day 544 |
381 |
0 |
|
|
|
Day 544 |
382 |
0 |
|
|
|
Day 544 |
383 |
0 |
|
|
|
Day 544 |
384 |
0 |
|
|
|
Day 544 |
385 |
0 |
|
|
|
Day 553 |
221 |
0 |
|
332.9 |
|
Day 563 |
309 |
100 |
|
299.4 |
|
Day 576 |
182 |
0 |
|
281.9 |
|
Day 586 |
343 |
100 |
|
237.7 |
|
Day 590 |
241 |
50 |
|
251.6 |
|
Day 599 |
267 |
50 |
|
278.3 |
|
Day 603 |
284 |
50 |
|
529 |
|
Day 604 |
188 |
0 |
|
320.4 |
|
Day 606 |
225 |
0 |
|
204 |
|
Day 606 |
274 |
50 |
|
388.8 |
|
Day 606 |
286 |
50 |
|
222.9 |
|
Day 606 |
304 |
100 |
|
198.7 |
|
Day 606 |
349 |
100 |
|
209.1 |
|
Day 611 |
214 |
0 |
|
205.9 |
|
Day 616 |
209 |
0 |
|
312.4 |
|
Day 617 |
269 |
50 |
|
575.4 |
|
Day 619 |
305 |
100 |
|
195.2 |
|
Day 620 |
218 |
0 |
|
210 |
|
Day 620 |
278 |
50 |
|
271.8 |
|
Day 625 |
317 |
100 |
|
203.5 |
|
Day 629 |
351 |
100 |
|
166.6 |
|
Day 640 |
190 |
0 |
|
217.8 |
|
Day 641 |
204 |
0 |
|
215.9 |
|
Day 642 |
227 |
0 |
|
330.1 |
|
Day 642 |
298 |
50 |
|
205.9 |
|
Day 642 |
359 |
100 |
|
332.9 |
|
Day 663 |
232 |
0 |
|
243.2 |
|
Day 663 |
346 |
100 |
|
232.6 |
|
Day 670 |
215 |
0 |
|
214.9 |
|
Day 674 |
330 |
100 |
|
279.7 |
|
Day 677 |
273 |
50 |
|
360.8 |
|
Day 678 |
345 |
100 |
|
260 |
|
Day 684 |
257 |
50 |
|
259.1 |
|
Day 689 |
268 |
50 |
|
248.8 |
|
Day 691 |
256 |
50 |
|
293.1 |
|
Day 695 |
183 |
0 |
|
256.1 |
|
Day 695 |
289 |
50 |
|
231.9 |
|
Day 705 |
205 |
0 |
|
229.9 |
|
Day 705 |
230 |
0 |
|
307.7 |
|
Day 705 |
251 |
50 |
|
256.4 |
|
Day 705 |
301 |
100 |
|
594.2 |
|
Day 707 |
239 |
0 |
|
462.3 |
|
Day 711 |
189 |
0 |
|
299.6 |
|
Day 711 |
308 |
100 |
|
241.6 |
|
Day 715 |
206 |
0 |
|
243.4 |
|
Day 719 |
212 |
0 |
|
427.3 |
|
Day 720 |
310 |
100 |
|
366.5 |
|
Day 720 |
316 |
100 |
|
242.5 |
|
Day 723 |
184 |
0 |
|
347.3 |
|
Day 723 |
236 |
0 |
|
284.9 |
|
Day 723 |
272 |
50 |
|
250.7 |
|
Day 723 |
281 |
50 |
|
376.2 |
|
Day 723 |
291 |
50 |
|
358.6 |
|
Day 723 |
295 |
50 |
|
337.6 |
|
Day 726 |
207 |
0 |
|
400.2 |
|
Day 726 |
338 |
100 |
|
246.4 |
|
Day 726 |
339 |
100 |
|
238.8 |
|
Day 729 |
181 |
0 |
|
339.6 |
|
Day 729 |
185 |
0 |
|
299.6 |
|
Day 729 |
186 |
0 |
|
309 |
|
Day 729 |
191 |
0 |
|
325.6 |
|
Day 729 |
194 |
0 |
|
309.4 |
|
Day 729 |
195 |
0 |
|
337.1 |
|
Day 729 |
196 |
0 |
|
330.6 |
|
Day 729 |
197 |
0 |
|
213.9 |
|
Day 729 |
198 |
0 |
|
306.6 |
|
Day 729 |
199 |
0 |
|
331.9 |
|
Day 729 |
200 |
0 |
|
360.7 |
|
Day 730 |
201 |
0 |
|
331 |
|
Day 730 |
202 |
0 |
|
356.9 |
|
Day 730 |
203 |
0 |
|
344.5 |
|
Day 730 |
208 |
0 |
|
299.9 |
|
Day 730 |
210 |
0 |
|
295.4 |
|
Day 730 |
211 |
0 |
|
331.7 |
|
Day 730 |
213 |
0 |
|
328.2 |
|
Day 730 |
216 |
0 |
|
361.8 |
|
Day 730 |
217 |
0 |
|
325 |
|
Day 730 |
219 |
0 |
|
354.7 |
|
Day 730 |
220 |
0 |
|
330 |
|
Day 730 |
222 |
0 |
|
316.4 |
|
Day 730 |
223 |
0 |
|
343.1 |
|
Day 730 |
226 |
0 |
|
344.8 |
|
Day 730 |
229 |
0 |
|
328.2 |
|
Day 730 |
231 |
0 |
|
272.3 |
|
Day 730 |
234 |
0 |
|
329 |
|
Day 730 |
237 |
0 |
|
347.3 |
|
Day 730 |
238 |
0 |
|
327 |
|
Day 730 |
240 |
0 |
|
334.7 |
|
Day 731 |
243 |
50 |
|
275.2 |
|
Day 731 |
250 |
50 |
|
306.9 |
|
Day 731 |
252 |
50 |
|
366.6 |
|
Day 731 |
254 |
50 |
|
318.4 |
|
Day 731 |
255 |
50 |
|
368.3 |
|
Day 731 |
260 |
50 |
|
294.3 |
|
Day 731 |
261 |
50 |
|
293.3 |
|
Day 731 |
262 |
50 |
|
312.3 |
|
Day 731 |
263 |
50 |
|
299.8 |
|
Day 731 |
264 |
50 |
|
325.9 |
|
Day 731 |
265 |
50 |
|
320.8 |
|
Day 731 |
266 |
50 |
|
366.5 |
|
Day 731 |
270 |
50 |
|
328 |
|
Day 731 |
302 |
100 |
|
224.1 |
|
Day 732 |
275 |
50 |
|
342 |
|
Day 732 |
276 |
50 |
|
315 |
|
Day 732 |
277 |
50 |
|
338.1 |
|
Day 732 |
279 |
50 |
|
288.8 |
|
Day 732 |
282 |
50 |
|
347 |
|
Day 732 |
283 |
50 |
|
280.4 |
|
Day 732 |
287 |
50 |
|
335.6 |
|
Day 732 |
288 |
50 |
|
318.2 |
|
Day 732 |
290 |
50 |
|
299 |
|
Day 732 |
292 |
50 |
|
310.8 |
|
Day 732 |
293 |
50 |
|
300.5 |
|
Day 732 |
296 |
50 |
|
307.4 |
|
Day 732 |
297 |
50 |
|
314.8 |
|
Day 732 |
299 |
50 |
|
297 |
|
Day 732 |
303 |
100 |
|
291.1 |
|
Day 732 |
307 |
100 |
|
302.9 |
|
Day 732 |
311 |
100 |
|
292 |
|
Day 732 |
312 |
100 |
|
346.1 |
|
Day 732 |
314 |
100 |
|
273 |
|
Day 732 |
315 |
100 |
|
335.9 |
|
Day 732 |
318 |
100 |
|
315.3 |
|
Day 732 |
324 |
100 |
|
354.5 |
|
Day 732 |
327 |
100 |
|
299.7 |
|
Day 732 |
332 |
100 |
|
272.5 |
|
Day 732 |
333 |
100 |
|
231.1 |
|
Day 732 |
334 |
100 |
|
352.8 |
|
Day 732 |
335 |
100 |
|
260.6 |
|
Day 732 |
336 |
100 |
|
299.4 |
|
Day 732 |
337 |
100 |
|
285 |
|
Day 732 |
340 |
100 |
|
263.3 |
|
Day 732 |
342 |
100 |
|
215.7 |
|
Day 732 |
344 |
100 |
|
331.1 |
|
Day 732 |
347 |
100 |
|
216.4 |
|
Day 732 |
350 |
100 |
|
275.4 |
|
Day 732 |
352 |
100 |
|
295.4 |
|
Day 732 |
353 |
100 |
|
332.7 |
|
Day 732 |
354 |
100 |
|
333.4 |
|
Day 732 |
355 |
100 |
|
324.5 |
|
Day 732 |
357 |
100 |
|
242.4 |
|
Day 732 |
358 |
100 |
|
296.9 |
|
Abbreviations: |
NA: Not Available
|