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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Talc |
CASRN: | ="14807-96-6" |
Study Number: | C06008 |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | RESPIRATORY EXPOSURE WHOLE BODY |
TDMS Number: | 0507901 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group () |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 180 |
426 |
0 |
|
162.9 |
|
Day 192 |
325 |
0 |
|
194.1 |
|
Day 192 |
41 |
6 |
|
216.1 |
|
Day 192 |
159 |
18 |
|
220.4 |
|
Day 193 |
375 |
0 |
|
223.7 |
|
Day 193 |
93 |
6 |
|
214.7 |
|
Day 193 |
210 |
18 |
|
216.2 |
|
Day 194 |
431 |
0 |
|
227.9 |
|
Day 194 |
139 |
6 |
|
199.9 |
|
Day 194 |
284 |
18 |
|
197.9 |
|
Day 333 |
309 |
0 |
|
240.4 |
|
Day 333 |
360 |
0 |
|
254.7 |
|
Day 333 |
378 |
0 |
|
265.8 |
|
Day 333 |
22 |
6 |
|
240.6 |
|
Day 333 |
42 |
6 |
|
258.4 |
|
Day 333 |
72 |
6 |
|
246.5 |
|
Day 333 |
188 |
18 |
|
256.9 |
|
Day 333 |
234 |
18 |
|
255.9 |
|
Day 333 |
262 |
18 |
|
226.6 |
|
Day 370 |
335 |
0 |
|
251 |
|
Day 376 |
237 |
18 |
|
214.4 |
|
Day 390 |
430 |
0 |
|
257.4 |
|
Day 398 |
377 |
0 |
|
205.8 |
|
Day 450 |
349 |
0 |
|
201.9 |
|
Day 482 |
38 |
6 |
|
276.5 |
|
Day 508 |
48 |
6 |
|
252.5 |
|
Day 510 |
87 |
6 |
|
186.8 |
|
Day 526 |
68 |
6 |
|
221 |
|
Day 536 |
167 |
18 |
|
254.3 |
|
Day 556 |
334 |
0 |
|
294.3 |
|
Day 556 |
354 |
0 |
|
308.5 |
|
Day 556 |
401 |
0 |
|
311.3 |
|
Day 556 |
120 |
6 |
|
273.1 |
|
Day 556 |
134 |
6 |
|
270.7 |
|
Day 556 |
94 |
6 |
|
282.3 |
|
Day 556 |
168 |
18 |
|
283.1 |
|
Day 556 |
187 |
18 |
|
272.4 |
|
Day 556 |
229 |
18 |
|
283 |
|
Day 557 |
137 |
6 |
|
257.2 |
|
Day 558 |
306 |
0 |
|
217.2 |
|
Day 558 |
280 |
18 |
|
283.4 |
|
Day 558 |
283 |
18 |
|
195.1 |
|
Day 561 |
69 |
6 |
|
162.2 |
|
Day 566 |
43 |
6 |
|
220.3 |
|
Day 566 |
95 |
6 |
|
247 |
|
Day 568 |
350 |
0 |
|
231.6 |
|
Day 584 |
357 |
0 |
|
203.8 |
|
Day 586 |
432 |
0 |
|
301.9 |
|
Day 586 |
216 |
18 |
|
178.6 |
|
Day 594 |
185 |
18 |
|
165.1 |
|
Day 594 |
212 |
18 |
|
179.5 |
|
Day 599 |
429 |
0 |
|
192.2 |
|
Day 615 |
183 |
18 |
|
204.9 |
|
Day 621 |
211 |
18 |
|
198.6 |
|
Day 621 |
278 |
18 |
|
165.9 |
|
Day 622 |
404 |
0 |
|
200 |
|
Day 625 |
13 |
6 |
|
213 |
|
Day 626 |
358 |
0 |
|
213.3 |
|
Day 633 |
285 |
18 |
|
219.3 |
|
Day 634 |
384 |
0 |
|
346.8 |
|
Day 646 |
230 |
18 |
|
184.2 |
|
Day 647 |
302 |
0 |
|
211.4 |
|
Day 647 |
110 |
6 |
|
175.4 |
|
Day 648 |
261 |
18 |
|
254.1 |
|
Day 650 |
161 |
18 |
|
145.7 |
|
Day 651 |
96 |
6 |
|
260.4 |
|
Day 660 |
281 |
18 |
|
174 |
|
Day 661 |
186 |
18 |
|
322.6 |
|
Day 668 |
141 |
6 |
|
153.1 |
|
Day 673 |
398 |
0 |
|
280.7 |
|
Day 675 |
288 |
18 |
|
200 |
|
Day 676 |
207 |
18 |
|
203.4 |
|
Day 677 |
376 |
0 |
|
150.1 |
|
Day 677 |
260 |
18 |
|
220.9 |
|
Day 678 |
402 |
0 |
|
360.1 |
|
Day 678 |
118 |
6 |
|
189.9 |
|
Day 678 |
255 |
18 |
|
353.3 |
|
Day 684 |
208 |
18 |
|
182.2 |
|
Day 688 |
308 |
0 |
|
215.3 |
|
Day 690 |
45 |
6 |
|
206.7 |
|
Day 693 |
240 |
18 |
|
202 |
|
Day 696 |
359 |
0 |
|
257.4 |
|
Day 697 |
92 |
6 |
|
186.9 |
|
Day 697 |
189 |
18 |
|
166.4 |
|
Day 698 |
184 |
18 |
|
199.4 |
|
Day 705 |
70 |
6 |
|
193.5 |
|
Day 706 |
206 |
18 |
|
212.5 |
|
Day 710 |
160 |
18 |
|
267.6 |
|
Day 716 |
327 |
0 |
|
268.1 |
|
Day 716 |
405 |
0 |
|
195.5 |
|
Day 716 |
113 |
6 |
|
222.3 |
|
Day 716 |
282 |
18 |
|
165.4 |
|
Day 717 |
236 |
18 |
|
169 |
|
Day 718 |
421 |
0 |
|
172.2 |
|
Day 719 |
305 |
0 |
|
221.8 |
|
Day 720 |
40 |
6 |
|
180 |
|
Day 724 |
109 |
6 |
|
272.2 |
|
Day 724 |
256 |
18 |
|
236.6 |
|
Day 726 |
214 |
18 |
|
139.3 |
|
Day 727 |
406 |
0 |
|
302.7 |
|
Day 728 |
379 |
0 |
|
196.8 |
|
Day 729 |
116 |
6 |
|
221.9 |
|
Day 731 |
397 |
0 |
|
181.9 |
|
Day 734 |
90 |
6 |
|
231.4 |
|
Day 738 |
89 |
6 |
|
219.4 |
|
Day 739 |
307 |
0 |
|
229 |
|
Day 739 |
310 |
0 |
|
318 |
|
Day 739 |
333 |
0 |
|
304 |
|
Day 739 |
353 |
0 |
|
304 |
|
Day 739 |
423 |
0 |
|
326 |
|
Day 739 |
114 |
6 |
|
289.1 |
|
Day 739 |
119 |
6 |
|
256.1 |
|
Day 739 |
135 |
6 |
|
308.8 |
|
Day 739 |
142 |
6 |
|
338.1 |
|
Day 739 |
15 |
6 |
|
298 |
|
Day 739 |
19 |
6 |
|
283 |
|
Day 739 |
46 |
6 |
|
287.5 |
|
Day 739 |
61 |
6 |
|
260.6 |
|
Day 739 |
65 |
6 |
|
338.1 |
|
Day 739 |
181 |
18 |
|
247.2 |
|
Day 739 |
213 |
18 |
|
307.8 |
|
Day 739 |
235 |
18 |
|
221.7 |
|
Day 739 |
279 |
18 |
|
257.8 |
|
Day 740 |
115 |
6 |
|
344 |
|
Day 740 |
263 |
18 |
|
236.4 |
|
Day 746 |
192 |
18 |
|
150.6 |
|
Day 747 |
39 |
6 |
|
233.2 |
|
Day 747 |
239 |
18 |
|
226.5 |
|
Day 755 |
112 |
6 |
|
311.3 |
|
Day 760 |
67 |
6 |
|
184.1 |
|
Day 762 |
382 |
0 |
|
233.6 |
|
Day 762 |
23 |
6 |
|
217.3 |
|
Day 766 |
351 |
0 |
|
183.5 |
|
Day 766 |
17 |
6 |
|
325.9 |
|
Day 767 |
328 |
0 |
|
163.9 |
|
Day 768 |
326 |
0 |
|
205.5 |
|
Day 768 |
63 |
6 |
|
159.4 |
|
Day 772 |
331 |
0 |
|
219.2 |
|
Day 773 |
209 |
18 |
|
199.2 |
|
Day 779 |
408 |
0 |
|
191.3 |
|
Day 784 |
257 |
18 |
|
185.2 |
|
Day 786 |
425 |
0 |
|
183.3 |
|
Day 786 |
144 |
6 |
|
206.1 |
|
Day 786 |
287 |
18 |
|
167.2 |
|
Day 789 |
311 |
0 |
|
336.7 |
|
Day 796 |
233 |
18 |
|
177.9 |
|
Day 798 |
143 |
6 |
|
199.3 |
|
Day 798 |
24 |
6 |
|
188.6 |
|
Day 799 |
138 |
6 |
|
185.6 |
|
Day 800 |
355 |
0 |
|
182.4 |
|
Day 800 |
85 |
6 |
|
172.4 |
|
Day 803 |
253 |
18 |
|
154.5 |
|
Day 805 |
336 |
0 |
|
164.6 |
|
Day 808 |
301 |
0 |
|
168.1 |
|
Day 812 |
14 |
6 |
|
209.1 |
|
Day 813 |
424 |
0 |
|
317.8 |
|
Day 815 |
37 |
6 |
|
153.2 |
|
Day 816 |
373 |
0 |
|
358.8 |
|
Day 817 |
427 |
0 |
|
184.6 |
|
Day 818 |
66 |
6 |
|
169.6 |
|
Day 819 |
117 |
6 |
|
211.8 |
|
Day 820 |
88 |
6 |
|
|
|
Day 822 |
162 |
18 |
|
201.8 |
|
Day 823 |
164 |
18 |
|
225.5 |
|
Day 824 |
383 |
0 |
|
198.9 |
|
Day 827 |
352 |
0 |
|
174.3 |
|
Day 828 |
157 |
18 |
|
272.2 |
|
Day 829 |
277 |
18 |
|
165.3 |
|
Day 835 |
374 |
0 |
|
231.9 |
|
Day 835 |
215 |
18 |
|
287.8 |
|
Day 841 |
356 |
0 |
|
350.9 |
|
Day 841 |
44 |
6 |
|
158 |
|
Day 841 |
190 |
18 |
|
159.7 |
|
Day 841 |
191 |
18 |
|
205 |
|
Day 842 |
205 |
18 |
|
183 |
|
Day 846 |
403 |
0 |
|
147.9 |
|
Day 848 |
258 |
18 |
|
164.2 |
|
Day 849 |
64 |
6 |
|
212.4 |
|
Day 850 |
264 |
18 |
|
143 |
|
Day 854 |
231 |
18 |
|
237.2 |
|
Day 857 |
165 |
18 |
|
168.7 |
|
Day 859 |
422 |
0 |
|
171.1 |
|
Day 862 |
303 |
0 |
|
236.3 |
|
Day 862 |
304 |
0 |
|
268.8 |
|
Day 862 |
312 |
0 |
|
272.7 |
|
Day 862 |
329 |
0 |
|
296.8 |
|
Day 862 |
330 |
0 |
|
276.6 |
|
Day 862 |
332 |
0 |
|
186.9 |
|
Day 862 |
16 |
6 |
|
296.5 |
|
Day 862 |
18 |
6 |
|
270.3 |
|
Day 862 |
20 |
6 |
|
256.3 |
|
Day 862 |
21 |
6 |
|
315.5 |
|
Day 862 |
47 |
6 |
|
251.9 |
|
Day 862 |
62 |
6 |
|
275.3 |
|
Day 862 |
71 |
6 |
|
290.2 |
|
Day 862 |
158 |
18 |
|
189.2 |
|
Day 862 |
163 |
18 |
|
232.3 |
|
Day 862 |
166 |
18 |
|
241.9 |
|
Day 862 |
182 |
18 |
|
273.3 |
|
Day 862 |
232 |
18 |
|
201.8 |
|
Day 863 |
380 |
0 |
|
165.1 |
|
Day 863 |
381 |
0 |
|
302.1 |
|
Day 863 |
399 |
0 |
|
280.9 |
|
Day 863 |
400 |
0 |
|
226.3 |
|
Day 863 |
407 |
0 |
|
292.7 |
|
Day 863 |
428 |
0 |
|
315.3 |
|
Day 863 |
111 |
6 |
|
274.3 |
|
Day 863 |
133 |
6 |
|
259.1 |
|
Day 863 |
136 |
6 |
|
172.4 |
|
Day 863 |
140 |
6 |
|
226.5 |
|
Day 863 |
86 |
6 |
|
154.7 |
|
Day 863 |
91 |
6 |
|
165.3 |
|
Day 863 |
238 |
18 |
|
245.6 |
|
Day 863 |
254 |
18 |
|
214.6 |
|
Day 863 |
259 |
18 |
|
242.3 |
|
Day 863 |
286 |
18 |
|
239 |
|
Abbreviations: |
NA: Not Available
|