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Short-Term Study
Body Weights
Study Information:
Chemical Name: | Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) |
CASRN: | ="21850-44-2" |
Study Number: | C20321 |
Exposure Route: | GAVAGE |
TDMS Number: | 2032101 |
Sex: | Female |
Strain and Species: | F344/N Tac Rats |
Animal Number |
Cage Number |
Dose Group |
Days On Study |
Week 1 |
Week 2 |
Week 3 |
Week 4 |
Week 5 |
Week 6 |
Week 7 |
Week 8 |
Week 9 |
Week 10 |
Week 11 |
Week 12 |
Week 14 |
Removal Reason |
61 |
13 |
Vehicle Control |
93 |
99.7 |
120.3 |
136.8 |
146 |
155.5 |
161.6 |
169.6 |
171.9 |
176 |
181.8 |
182.9 |
186.1 |
185.8 |
Terminal Sacrifice |
62 |
13 |
Vehicle Control |
93 |
88.5 |
104.8 |
118.7 |
129.9 |
137.7 |
149 |
153 |
158.1 |
165.7 |
169.4 |
170.5 |
175.6 |
178.8 |
Terminal Sacrifice |
63 |
13 |
Vehicle Control |
93 |
100.1 |
118.5 |
132.2 |
144.3 |
153.1 |
164.2 |
167.2 |
171 |
176.6 |
179.4 |
182.6 |
187.4 |
192.6 |
Terminal Sacrifice |
64 |
13 |
Vehicle Control |
93 |
98.6 |
117.1 |
129.4 |
141.4 |
148 |
155.6 |
161.2 |
165.9 |
170.1 |
174.2 |
176.7 |
181.3 |
182.6 |
Terminal Sacrifice |
65 |
13 |
Vehicle Control |
93 |
103.1 |
120.4 |
134.7 |
143.5 |
153.7 |
160.3 |
167.4 |
172.9 |
175.5 |
180.5 |
179.8 |
184.3 |
188.7 |
Terminal Sacrifice |
66 |
14 |
Vehicle Control |
51 |
101.5 |
120 |
134.2 |
148.5 |
157.9 |
168.1 |
179.7 |
169.9 |
|
|
|
|
|
Natural Death |
67 |
14 |
Vehicle Control |
93 |
105.8 |
125.6 |
145.7 |
160 |
171.6 |
179.8 |
188.1 |
193 |
198.6 |
205.9 |
207.5 |
215.3 |
214 |
Terminal Sacrifice |
68 |
14 |
Vehicle Control |
93 |
106.9 |
124.4 |
133.2 |
144.4 |
153.1 |
164.4 |
169.8 |
173.4 |
177.5 |
179 |
189.7 |
191.5 |
197 |
Terminal Sacrifice |
69 |
14 |
Vehicle Control |
93 |
98.4 |
116.9 |
134.4 |
145.9 |
150.3 |
159.1 |
167.3 |
166.6 |
171.3 |
177.6 |
180.4 |
182.1 |
182.9 |
Terminal Sacrifice |
70 |
14 |
Vehicle Control |
93 |
104.1 |
121.5 |
135.1 |
145.8 |
152.9 |
164.4 |
169.7 |
174.9 |
177.4 |
184.3 |
189 |
192.9 |
197.1 |
Terminal Sacrifice |
71 |
15 |
62.5mg/kg |
93 |
98.6 |
114.8 |
128.7 |
138.3 |
147.6 |
155.6 |
158.1 |
163.7 |
167.2 |
172.2 |
174.7 |
178.8 |
183.6 |
Terminal Sacrifice |
72 |
15 |
62.5mg/kg |
93 |
101.2 |
121.5 |
137.1 |
145.9 |
155.6 |
164.4 |
169.5 |
171.6 |
176.5 |
181.3 |
184.4 |
194.3 |
194.4 |
Terminal Sacrifice |
73 |
15 |
62.5mg/kg |
93 |
106 |
122.4 |
137.9 |
149.3 |
156 |
168.9 |
174.6 |
180.9 |
177.6 |
182.6 |
191.5 |
194.6 |
203.2 |
Terminal Sacrifice |
74 |
15 |
62.5mg/kg |
93 |
96.4 |
115.8 |
133.8 |
147.7 |
156.9 |
170.1 |
178.2 |
185.1 |
189.1 |
199.5 |
200.7 |
209.9 |
214.2 |
Terminal Sacrifice |
75 |
15 |
62.5mg/kg |
93 |
97.4 |
113.5 |
128.1 |
136.9 |
147.4 |
150.5 |
158 |
160.6 |
168.8 |
175.8 |
177.1 |
185.3 |
190.9 |
Terminal Sacrifice |
76 |
16 |
62.5mg/kg |
93 |
94.1 |
111.5 |
125 |
133.5 |
142.1 |
149.9 |
151.4 |
155.5 |
159.3 |
162.6 |
163.9 |
168 |
171.6 |
Terminal Sacrifice |
77 |
16 |
62.5mg/kg |
93 |
106.4 |
121.4 |
136.8 |
148 |
157.7 |
169.6 |
173 |
180 |
182.6 |
185 |
188.9 |
189.4 |
201.3 |
Terminal Sacrifice |
78 |
16 |
62.5mg/kg |
93 |
105.6 |
127.9 |
143.6 |
155.3 |
163.3 |
176.4 |
177 |
185.6 |
186.1 |
191.8 |
195.2 |
200 |
203.1 |
Terminal Sacrifice |
79 |
16 |
62.5mg/kg |
93 |
95.4 |
111.7 |
122.7 |
131.3 |
139 |
148.6 |
151.2 |
158.7 |
161 |
165.4 |
168.7 |
171.3 |
177.9 |
Terminal Sacrifice |
80 |
16 |
62.5mg/kg |
93 |
107.5 |
124.8 |
143.3 |
156.4 |
165.2 |
174.2 |
179.7 |
186.2 |
193.6 |
197.4 |
200.7 |
204.3 |
210.6 |
Terminal Sacrifice |
81 |
17 |
125mg/kg |
93 |
107.8 |
125.5 |
142.7 |
154.2 |
162.4 |
167.2 |
176.1 |
180.1 |
181.8 |
187.2 |
188.8 |
192.8 |
196.4 |
Terminal Sacrifice |
82 |
17 |
125mg/kg |
93 |
97 |
113.4 |
126.4 |
136.2 |
142.5 |
150.3 |
153.7 |
157.3 |
162.5 |
166.3 |
169.3 |
172.1 |
178.5 |
Terminal Sacrifice |
83 |
17 |
125mg/kg |
93 |
90.1 |
107.5 |
121 |
130 |
137.9 |
143.8 |
146.6 |
148 |
153.1 |
156.9 |
157.8 |
164.3 |
170 |
Terminal Sacrifice |
84 |
17 |
125mg/kg |
93 |
97.7 |
115.9 |
131.4 |
143.2 |
151.4 |
160.4 |
166.2 |
171.9 |
177.9 |
181.2 |
186.9 |
188.9 |
195.3 |
Terminal Sacrifice |
85 |
17 |
125mg/kg |
93 |
106.9 |
122.3 |
137.3 |
146.4 |
158 |
144.7 |
162.7 |
173.2 |
178.6 |
181.2 |
183.6 |
184.8 |
188.7 |
Terminal Sacrifice |
86 |
18 |
125mg/kg |
93 |
100.5 |
119.6 |
132.7 |
145.9 |
155.5 |
164.2 |
176.4 |
177.3 |
180.1 |
179.9 |
187.7 |
190.4 |
195.8 |
Terminal Sacrifice |
87 |
18 |
125mg/kg |
93 |
98.4 |
118.1 |
138.4 |
150.8 |
160.3 |
169 |
177.6 |
188.1 |
190.3 |
192.4 |
196.5 |
198.1 |
205.3 |
Terminal Sacrifice |
88 |
18 |
125mg/kg |
93 |
90.8 |
105.6 |
118.6 |
128.1 |
137.3 |
148.1 |
158.4 |
163.4 |
162.2 |
165.2 |
164 |
160.4 |
171.2 |
Terminal Sacrifice |
89 |
18 |
125mg/kg |
93 |
94.8 |
112.9 |
128.9 |
136.9 |
143.3 |
152.4 |
160.8 |
162.1 |
165.4 |
170.2 |
174 |
175 |
177.7 |
Terminal Sacrifice |
90 |
18 |
125mg/kg |
93 |
99.2 |
119.1 |
136.1 |
147.1 |
154.5 |
161.9 |
177.2 |
178.9 |
182.4 |
189.5 |
188.6 |
196.4 |
201.6 |
Terminal Sacrifice |
91 |
19 |
250mg/kg |
93 |
109.9 |
131.1 |
147.9 |
158.4 |
165.6 |
176.6 |
184.5 |
190.6 |
196.9 |
201.8 |
209.5 |
210.7 |
216.1 |
Terminal Sacrifice |
92 |
19 |
250mg/kg |
93 |
96.6 |
120.2 |
136.3 |
148.3 |
154.6 |
163.8 |
173.1 |
179.5 |
182.8 |
187.9 |
194.8 |
200.8 |
202 |
Terminal Sacrifice |
93 |
19 |
250mg/kg |
93 |
94 |
114.3 |
129.7 |
141.8 |
147.9 |
158.2 |
164.8 |
170.1 |
177.1 |
183.8 |
186.1 |
191.9 |
194 |
Terminal Sacrifice |
94 |
19 |
250mg/kg |
93 |
97 |
119.2 |
138.1 |
143.5 |
153.7 |
161.5 |
170.1 |
171.7 |
179.6 |
190.4 |
191.4 |
198.7 |
201 |
Terminal Sacrifice |
95 |
19 |
250mg/kg |
93 |
95 |
119.3 |
133 |
141.7 |
147.3 |
155.9 |
162.4 |
171.4 |
177.6 |
181.5 |
185.8 |
192.7 |
191.9 |
Terminal Sacrifice |
96 |
20 |
250mg/kg |
93 |
102.5 |
120.6 |
135.8 |
145.2 |
153.7 |
160.9 |
164.7 |
172.6 |
176.5 |
185.9 |
186.6 |
187.1 |
192.4 |
Terminal Sacrifice |
97 |
20 |
250mg/kg |
93 |
101.4 |
118.7 |
130.8 |
143.7 |
151.1 |
157.9 |
163.4 |
164.5 |
167.6 |
171.6 |
174.4 |
178.7 |
182.6 |
Terminal Sacrifice |
98 |
20 |
250mg/kg |
93 |
100.5 |
119 |
136.2 |
149.1 |
159.2 |
167.6 |
165.8 |
173.9 |
179.5 |
184.3 |
187 |
190.5 |
197.2 |
Terminal Sacrifice |
99 |
20 |
250mg/kg |
93 |
98.1 |
115 |
129.6 |
138.9 |
147.4 |
157.9 |
160.9 |
166.5 |
168.2 |
176.9 |
178.3 |
182.1 |
186.5 |
Terminal Sacrifice |
100 |
20 |
250mg/kg |
93 |
94.6 |
110.2 |
120.5 |
131.3 |
138.2 |
146.8 |
151.6 |
155.7 |
161.6 |
165.9 |
168.3 |
169.8 |
174.3 |
Terminal Sacrifice |
101 |
21 |
500mg/kg |
93 |
101.2 |
118.5 |
129.2 |
140.8 |
149.2 |
158.6 |
161.1 |
165.4 |
170.3 |
174.9 |
177.4 |
181.9 |
185.6 |
Terminal Sacrifice |
102 |
21 |
500mg/kg |
93 |
92.6 |
110.3 |
126.2 |
135.1 |
145 |
154.5 |
156.6 |
165.2 |
167 |
174.7 |
177.5 |
181.3 |
177.6 |
Terminal Sacrifice |
103 |
21 |
500mg/kg |
93 |
108.9 |
125.7 |
137.9 |
150.4 |
156.7 |
166.6 |
172.6 |
176.3 |
185.3 |
189.2 |
192.7 |
189.7 |
193.6 |
Terminal Sacrifice |
104 |
21 |
500mg/kg |
93 |
96.2 |
115.7 |
130.1 |
142.2 |
151.3 |
158 |
161.3 |
164.9 |
170 |
173.3 |
176.2 |
178.7 |
179.7 |
Terminal Sacrifice |
105 |
21 |
500mg/kg |
93 |
91.8 |
110.9 |
126.3 |
136.9 |
143 |
153.2 |
158.8 |
161.7 |
167.3 |
170.3 |
170.7 |
178.5 |
176.5 |
Terminal Sacrifice |
106 |
22 |
500mg/kg |
93 |
95.1 |
111.7 |
126 |
137.5 |
143.8 |
152.1 |
161.3 |
164.1 |
166.4 |
173.2 |
172.9 |
182.3 |
186.3 |
Terminal Sacrifice |
107 |
22 |
500mg/kg |
93 |
99.7 |
117.2 |
132.4 |
141.5 |
148.1 |
158.7 |
167 |
176.6 |
175.1 |
180.4 |
182.1 |
193.1 |
196 |
Terminal Sacrifice |
108 |
22 |
500mg/kg |
93 |
101.1 |
118.2 |
133.4 |
142.7 |
149.1 |
158.4 |
163.7 |
171.6 |
170.1 |
172 |
179.9 |
181.5 |
182.8 |
Terminal Sacrifice |
109 |
22 |
500mg/kg |
93 |
96.4 |
113.7 |
130.4 |
143.1 |
151 |
160.5 |
166.3 |
172.5 |
176.7 |
180.9 |
186.5 |
184.4 |
193 |
Terminal Sacrifice |
110 |
22 |
500mg/kg |
93 |
106.2 |
122.1 |
138.9 |
149.4 |
156.5 |
169.1 |
176.5 |
182.1 |
185.2 |
190.9 |
194.4 |
197.9 |
204.5 |
Terminal Sacrifice |
111 |
23 |
1000mg/kg |
93 |
100.2 |
119.1 |
135.2 |
146.7 |
158 |
167.1 |
176.1 |
184 |
187.1 |
193.1 |
192.8 |
201.3 |
208.6 |
Terminal Sacrifice |
112 |
23 |
1000mg/kg |
93 |
110.8 |
127.2 |
142.9 |
155 |
163.8 |
174.6 |
180.1 |
186.7 |
191 |
193.9 |
196.7 |
199.6 |
203.2 |
Terminal Sacrifice |
113 |
23 |
1000mg/kg |
93 |
99 |
116.7 |
131.4 |
141.2 |
149.7 |
158.7 |
161.9 |
169.9 |
171.8 |
176.6 |
177.8 |
181.8 |
182.8 |
Terminal Sacrifice |
114 |
23 |
1000mg/kg |
93 |
104.1 |
125.3 |
135.4 |
147.1 |
152.8 |
160.8 |
165.8 |
169.8 |
172.7 |
178.8 |
183.5 |
185.2 |
189.1 |
Terminal Sacrifice |
115 |
23 |
1000mg/kg |
93 |
99.7 |
115.1 |
129.4 |
140.8 |
147.9 |
158.5 |
163.8 |
171.5 |
177 |
181.2 |
186 |
187.7 |
193.8 |
Terminal Sacrifice |
116 |
24 |
1000mg/kg |
93 |
97.9 |
117 |
131.5 |
142.5 |
147.2 |
156.6 |
161.5 |
167.7 |
173.5 |
176.3 |
176.7 |
186.6 |
190.1 |
Terminal Sacrifice |
117 |
24 |
1000mg/kg |
93 |
99.6 |
117.2 |
132.7 |
143 |
150.7 |
161.6 |
166.5 |
175.9 |
177.2 |
182.9 |
185.5 |
188.5 |
193.7 |
Terminal Sacrifice |
118 |
24 |
1000mg/kg |
93 |
81.8 |
100.9 |
114 |
123.7 |
132.3 |
139.1 |
142.7 |
145.3 |
149 |
151.9 |
155.4 |
157.7 |
159.7 |
Terminal Sacrifice |
119 |
24 |
1000mg/kg |
93 |
91 |
108.7 |
123.2 |
131.6 |
142.9 |
149.7 |
156.7 |
161.2 |
163.1 |
166 |
168 |
177.9 |
177.4 |
Terminal Sacrifice |
120 |
24 |
1000mg/kg |
93 |
101 |
117.8 |
131.3 |
146.1 |
154.6 |
162.8 |
170.2 |
172.1 |
178.1 |
186 |
188.3 |
197.7 |
196.4 |
Terminal Sacrifice |
* All body weights in grams