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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Tetrahydrofuran |
CASRN: | ="109-99-9" |
Study Number: | C60560C |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | RESPIRATORY EXPOSURE WHOLE BODY |
TDMS Number: | 0518104 |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (PPM) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 7 |
645 |
1800 |
|
14.3 |
|
Day 99 |
639 |
1800 |
|
27.9 |
|
Day 102 |
619 |
1800 |
|
26.5 |
|
Day 189 |
623 |
1800 |
|
32.8 |
|
Day 190 |
634 |
1800 |
|
31.8 |
|
Day 191 |
606 |
1800 |
|
33.1 |
|
Day 229 |
602 |
1800 |
|
37.3 |
|
Day 239 |
604 |
1800 |
|
30.7 |
|
Day 240 |
601 |
1800 |
|
37.3 |
|
Day 245 |
610 |
1800 |
|
34.9 |
|
Day 260 |
605 |
1800 |
|
32.8 |
|
Day 265 |
650 |
1800 |
|
36.4 |
|
Day 273 |
640 |
1800 |
|
35.9 |
|
Day 275 |
612 |
1800 |
|
40 |
|
Day 275 |
618 |
1800 |
|
32.7 |
|
Day 313 |
614 |
1800 |
|
28.6 |
|
Day 314 |
233 |
200 |
|
34.3 |
|
Day 321 |
641 |
1800 |
|
35 |
|
Day 324 |
216 |
200 |
|
38.4 |
|
Day 335 |
646 |
1800 |
|
35 |
|
Day 346 |
625 |
1800 |
|
39.2 |
|
Day 349 |
649 |
1800 |
|
38.1 |
|
Day 359 |
608 |
1800 |
|
36.3 |
|
Day 359 |
621 |
1800 |
|
35.7 |
|
Day 359 |
626 |
1800 |
|
39.4 |
|
Day 359 |
630 |
1800 |
|
38 |
|
Day 359 |
644 |
1800 |
|
39.7 |
|
Day 359 |
648 |
1800 |
|
40.2 |
|
Day 362 |
23 |
0 |
|
44.2 |
|
Day 376 |
434 |
600 |
|
47.3 |
|
Day 386 |
638 |
1800 |
|
29 |
|
Day 414 |
607 |
1800 |
|
33 |
|
Day 440 |
13 |
0 |
|
50.5 |
|
Day 440 |
441 |
600 |
|
41.2 |
|
Day 441 |
214 |
200 |
|
39.4 |
|
Day 452 |
628 |
1800 |
|
40.9 |
|
Day 475 |
204 |
200 |
|
43.4 |
|
Day 481 |
35 |
0 |
|
36.6 |
|
Day 504 |
432 |
600 |
|
37.4 |
|
Day 512 |
417 |
600 |
|
38 |
|
Day 526 |
223 |
200 |
|
35.4 |
|
Day 527 |
613 |
1800 |
|
35.5 |
|
Day 532 |
239 |
200 |
|
47.4 |
|
Day 544 |
8 |
0 |
|
31.4 |
|
Day 544 |
225 |
200 |
|
|
|
Day 551 |
422 |
600 |
|
43.5 |
|
Day 554 |
235 |
200 |
|
36.9 |
|
Day 554 |
240 |
200 |
|
38.7 |
|
Day 554 |
443 |
600 |
|
44.3 |
|
Day 554 |
643 |
1800 |
|
39.7 |
|
Day 557 |
38 |
0 |
|
42.3 |
|
Day 558 |
410 |
600 |
|
39.1 |
|
Day 560 |
436 |
600 |
|
52.5 |
|
Day 569 |
425 |
600 |
|
37.4 |
|
Day 574 |
244 |
200 |
|
44.8 |
|
Day 574 |
439 |
600 |
|
37.8 |
|
Day 574 |
444 |
600 |
|
33.3 |
|
Day 577 |
222 |
200 |
|
|
|
Day 582 |
19 |
0 |
|
35.6 |
|
Day 582 |
44 |
0 |
|
38.8 |
|
Day 582 |
447 |
600 |
|
37.5 |
|
Day 594 |
418 |
600 |
|
41.2 |
|
Day 594 |
442 |
600 |
|
33.1 |
|
Day 595 |
438 |
600 |
|
48.6 |
|
Day 604 |
411 |
600 |
|
31.8 |
|
Day 631 |
407 |
600 |
|
35.7 |
|
Day 638 |
20 |
0 |
|
34.1 |
|
Day 638 |
40 |
0 |
|
36.7 |
|
Day 638 |
237 |
200 |
|
30 |
|
Day 639 |
647 |
1800 |
|
38.8 |
|
Day 644 |
37 |
0 |
|
45.9 |
|
Day 644 |
229 |
200 |
|
38.6 |
|
Day 644 |
429 |
600 |
|
48.3 |
|
Day 646 |
249 |
200 |
|
32.4 |
|
Day 658 |
22 |
0 |
|
38.1 |
|
Day 658 |
424 |
600 |
|
32.6 |
|
Day 658 |
620 |
1800 |
|
39.4 |
|
Day 666 |
211 |
200 |
|
30.3 |
|
Day 666 |
414 |
600 |
|
35.7 |
|
Day 670 |
1 |
0 |
|
46 |
|
Day 670 |
633 |
1800 |
|
39.2 |
|
Day 675 |
14 |
0 |
|
25.1 |
|
Day 678 |
21 |
0 |
|
30.2 |
|
Day 685 |
245 |
200 |
|
40.1 |
|
Day 687 |
617 |
1800 |
|
53.1 |
|
Day 690 |
29 |
0 |
|
36.1 |
|
Day 694 |
231 |
200 |
|
34.9 |
|
Day 694 |
402 |
600 |
|
44.8 |
|
Day 699 |
41 |
0 |
|
32.4 |
|
Day 706 |
212 |
200 |
|
31.6 |
|
Day 706 |
635 |
1800 |
|
37.2 |
|
Day 713 |
232 |
200 |
|
38 |
|
Day 715 |
627 |
1800 |
|
41.9 |
|
Day 719 |
5 |
0 |
|
46.2 |
|
Day 721 |
26 |
0 |
|
29.4 |
|
Day 721 |
430 |
600 |
|
31.3 |
|
Day 721 |
603 |
1800 |
|
34.5 |
|
Day 733 |
25 |
0 |
|
49.6 |
|
Day 733 |
27 |
0 |
|
52.5 |
|
Day 733 |
32 |
0 |
|
50.4 |
|
Day 733 |
33 |
0 |
|
54.4 |
|
Day 733 |
39 |
0 |
|
55.2 |
|
Day 733 |
42 |
0 |
|
47 |
|
Day 733 |
43 |
0 |
|
48.4 |
|
Day 733 |
49 |
0 |
|
51.5 |
|
Day 733 |
50 |
0 |
|
52.2 |
|
Day 733 |
6 |
0 |
|
50.8 |
|
Day 733 |
205 |
200 |
|
46.2 |
|
Day 733 |
226 |
200 |
|
45.2 |
|
Day 733 |
243 |
200 |
|
50.9 |
|
Day 733 |
246 |
200 |
|
49.4 |
|
Day 733 |
403 |
600 |
|
53.1 |
|
Day 733 |
409 |
600 |
|
41.3 |
|
Day 733 |
426 |
600 |
|
52.9 |
|
Day 733 |
428 |
600 |
|
52.6 |
|
Day 733 |
437 |
600 |
|
49.6 |
|
Day 733 |
448 |
600 |
|
55.6 |
|
Day 733 |
449 |
600 |
|
40.3 |
|
Day 733 |
450 |
600 |
|
43.1 |
|
Day 733 |
609 |
1800 |
|
44.3 |
|
Day 733 |
636 |
1800 |
|
44.9 |
|
Day 733 |
642 |
1800 |
|
53.4 |
|
Day 734 |
12 |
0 |
|
50.3 |
|
Day 734 |
16 |
0 |
|
42.1 |
|
Day 734 |
2 |
0 |
|
52.2 |
|
Day 734 |
30 |
0 |
|
42.6 |
|
Day 734 |
34 |
0 |
|
46.2 |
|
Day 734 |
36 |
0 |
|
48.2 |
|
Day 734 |
4 |
0 |
|
46.9 |
|
Day 734 |
48 |
0 |
|
46 |
|
Day 734 |
9 |
0 |
|
49.2 |
|
Day 734 |
201 |
200 |
|
51.6 |
|
Day 734 |
203 |
200 |
|
47.5 |
|
Day 734 |
208 |
200 |
|
55.2 |
|
Day 734 |
217 |
200 |
|
51.9 |
|
Day 734 |
221 |
200 |
|
38.9 |
|
Day 734 |
228 |
200 |
|
51.8 |
|
Day 734 |
230 |
200 |
|
38.1 |
|
Day 734 |
234 |
200 |
|
39.5 |
|
Day 734 |
238 |
200 |
|
53.6 |
|
Day 734 |
404 |
600 |
|
55.8 |
|
Day 734 |
406 |
600 |
|
51.9 |
|
Day 734 |
412 |
600 |
|
53.4 |
|
Day 734 |
416 |
600 |
|
48.9 |
|
Day 734 |
419 |
600 |
|
48 |
|
Day 734 |
420 |
600 |
|
50.2 |
|
Day 734 |
423 |
600 |
|
52 |
|
Day 734 |
431 |
600 |
|
49.5 |
|
Day 734 |
433 |
600 |
|
49.1 |
|
Day 734 |
446 |
600 |
|
49.4 |
|
Day 734 |
622 |
1800 |
|
35.8 |
|
Day 734 |
629 |
1800 |
|
57.8 |
|
Day 734 |
637 |
1800 |
|
46.2 |
|
Day 736 |
10 |
0 |
|
42.4 |
|
Day 736 |
15 |
0 |
|
50.7 |
|
Day 736 |
17 |
0 |
|
52.9 |
|
Day 736 |
18 |
0 |
|
44.3 |
|
Day 736 |
3 |
0 |
|
48.3 |
|
Day 736 |
31 |
0 |
|
48 |
|
Day 736 |
45 |
0 |
|
43.3 |
|
Day 736 |
46 |
0 |
|
39 |
|
Day 736 |
47 |
0 |
|
52.4 |
|
Day 736 |
206 |
200 |
|
54.1 |
|
Day 736 |
207 |
200 |
|
45.9 |
|
Day 736 |
209 |
200 |
|
45.6 |
|
Day 736 |
210 |
200 |
|
50.8 |
|
Day 736 |
213 |
200 |
|
46.1 |
|
Day 736 |
219 |
200 |
|
53.1 |
|
Day 736 |
220 |
200 |
|
48.6 |
|
Day 736 |
236 |
200 |
|
51.6 |
|
Day 736 |
247 |
200 |
|
47.4 |
|
Day 736 |
401 |
600 |
|
50 |
|
Day 736 |
408 |
600 |
|
55.9 |
|
Day 736 |
413 |
600 |
|
46.7 |
|
Day 736 |
415 |
600 |
|
49.9 |
|
Day 736 |
427 |
600 |
|
54.1 |
|
Day 736 |
435 |
600 |
|
44.5 |
|
Day 736 |
440 |
600 |
|
52.2 |
|
Day 736 |
611 |
1800 |
|
51.8 |
|
Day 736 |
615 |
1800 |
|
53.1 |
|
Day 736 |
616 |
1800 |
|
55.1 |
|
Day 736 |
624 |
1800 |
|
53 |
|
Day 736 |
631 |
1800 |
|
53.1 |
|
Day 736 |
632 |
1800 |
|
46.7 |
|
Day 737 |
11 |
0 |
|
53.4 |
|
Day 737 |
24 |
0 |
|
53.6 |
|
Day 737 |
28 |
0 |
|
47.3 |
|
Day 737 |
7 |
0 |
|
48.1 |
|
Day 737 |
202 |
200 |
|
54.1 |
|
Day 737 |
215 |
200 |
|
46.1 |
|
Day 737 |
218 |
200 |
|
54.9 |
|
Day 737 |
224 |
200 |
|
44.4 |
|
Day 737 |
227 |
200 |
|
52.5 |
|
Day 737 |
241 |
200 |
|
46.1 |
|
Day 737 |
242 |
200 |
|
55.4 |
|
Day 737 |
248 |
200 |
|
47.4 |
|
Day 737 |
250 |
200 |
|
52.6 |
|
Day 737 |
405 |
600 |
|
47.4 |
|
Day 737 |
421 |
600 |
|
47.8 |
|
Day 737 |
445 |
600 |
|
47.3 |
|
Abbreviations: |
NA: Not Available
|