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Long-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name:	Toxaphene
CASRN:	="8001-35-2"
Study Number:	C00259
Exposure Route:	Dosed-Feed
TDMS Number:
Sex:	Male
Strain and Species:	B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses

System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason

Alimentary System Liver Vehicle Control 10 NA 1_037 95.00 1 Focal Cellular Change Scheduled Sacrifice

Genital System Testis 160 PPM 49 NA 2_288 95.00 1 Atrophy, Nos Scheduled Sacrifice

Hematopoietic System Lymph node Mesenteric Lymph Node 160 PPM 48 NA 2_299 95.00 1 Hyperplasia, Nos Scheduled Sacrifice

Hematopoietic System Lymph node 160 PPM 36 NA 2_284 95.00 1 Inflammation, Chronic Scheduled Sacrifice

Integumentary System Skin 160 PPM 49 NA 2_275 95.00 1 Inflammation, Acute/Chronic Scheduled Sacrifice

System	Organ	Site	Treatment Group	Number Examined	Cage Number	Animal Number	Weeks on Study	Lesion Found	Lesion Name	Removal Reason
Alimentary System	Liver		Vehicle Control	10	NA	1_037	95.00	1	Focal Cellular Change	Scheduled Sacrifice
Genital System	Testis		160 PPM	49	NA	2_288	95.00	1	Atrophy, Nos	Scheduled Sacrifice
Hematopoietic System	Lymph node	Mesenteric Lymph Node	160 PPM	48	NA	2_299	95.00	1	Hyperplasia, Nos	Scheduled Sacrifice
Hematopoietic System	Lymph node		160 PPM	36	NA	2_284	95.00	1	Inflammation, Chronic	Scheduled Sacrifice
Integumentary System	Skin		160 PPM	49	NA	2_275	95.00	1	Inflammation, Acute/Chronic	Scheduled Sacrifice