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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name:	alpha-Thujone
CASRN:	="546-80-5"
Study Number:	C99021
Exposure Route:	GAVAGE
TDMS Number:	9902197
Sex:	Female
Strain and Species:	B6C3F1 Mice

Female Individual Animal Non Neoplastic Diagnoses

System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason

Alimentary System Esophagus Muscularis 100 MG/KG 4 30 48 6 1 Necrosis Minimal, Focal Natural Death

Hematopoietic System Bone Marrow Myeloid Cell 100 MG/KG 4 30 48 6 1 Hyperplasia Mild Natural Death

Hematopoietic System Spleen 100 MG/KG 4 30 45 9 1 Hematopoietic Cell Proliferation Mild Natural Death

Hematopoietic System Spleen 100 MG/KG 4 30 48 6 1 Hematopoietic Cell Proliferation Mild Natural Death

Urinary System Kidney Renal Tubule 100 MG/KG 4 30 45 9 1 Dilatation Minimal, Focal Natural Death

System	Organ	Site	Treatment Group	Number Examined	Cage Number	Animal Number	Days on Study	Lesion Found	Lesion Name	Lesion Qualifier	Removal Reason
Alimentary System	Esophagus	Muscularis	100 MG/KG	4	30	48	6	1	Necrosis	Minimal, Focal	Natural Death
Hematopoietic System	Bone Marrow	Myeloid Cell	100 MG/KG	4	30	48	6	1	Hyperplasia	Mild	Natural Death
Hematopoietic System	Spleen		100 MG/KG	4	30	45	9	1	Hematopoietic Cell Proliferation	Mild	Natural Death
Hematopoietic System	Spleen		100 MG/KG	4	30	48	6	1	Hematopoietic Cell Proliferation	Mild	Natural Death
Urinary System	Kidney	Renal Tubule	100 MG/KG	4	30	45	9	1	Dilatation	Minimal, Focal	Natural Death