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Short-Term Individual Animal Non Neoplastic Diagnosis
Study Information:
Chemical Name: | beta-Myrcene |
CASRN: | ="123-35-3" |
Study Number: | C99023 |
Exposure Route: | GAVAGE |
TDMS Number: | 9902302 |
Sex: | Female |
Strain and Species: | B6C3F1 Mice |
Female Individual Animal Non Neoplastic Diagnoses
System |
Organ |
Site |
Treatment Group |
Number Examined |
Cage Number |
Animal Number |
Days on Study |
Lesion Found |
Lesion Name |
Lesion Qualifier |
Removal Reason |
Alimentary System |
Esophagus |
Epithelium, Muscularis |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Inflammation |
Mild, Suppurative |
Natural Death |
Alimentary System |
Liver |
Centrilobular |
1.0 G/KG |
10 |
67 |
451 |
93 |
1 |
Hypertrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
Centrilobular |
1.0 G/KG |
10 |
68 |
456 |
93 |
1 |
Hypertrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
Centrilobular |
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Hypertrophy |
Minimal |
Natural Death |
Alimentary System |
Liver |
Centrilobular |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Hypertrophy |
Minimal |
Natural Death |
Alimentary System |
Liver |
Centrilobular |
2.0 G/KG |
10 |
70 |
557 |
93 |
1 |
Hypertrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
Centrilobular |
2.0 G/KG |
10 |
70 |
558 |
93 |
1 |
Hypertrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
Centrilobular |
2.0 G/KG |
10 |
69 |
555 |
23 |
1 |
Necrosis |
Mild |
Natural Death |
Alimentary System |
Liver |
Centrilobular |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Necrosis |
Mild |
Natural Death |
Alimentary System |
Liver |
Centrilobular |
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Necrosis |
Mild |
Natural Death |
Alimentary System |
Liver |
Centrilobular |
4.0 G/KG |
10 |
71 |
653 |
2 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Alimentary System |
Liver |
Centrilobular |
4.0 G/KG |
10 |
72 |
657 |
2 |
1 |
Necrosis |
Minimal |
Moribund Sacrifice |
Alimentary System |
Liver |
Centrilobular |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Necrosis |
Marked |
Moribund Sacrifice |
Alimentary System |
Liver |
Centrilobular |
4.0 G/KG |
10 |
72 |
659 |
2 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Alimentary System |
Liver |
Centrilobular |
4.0 G/KG |
10 |
72 |
660 |
2 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Alimentary System |
Liver |
Centrilobular |
4.0 G/KG |
10 |
71 |
651 |
2 |
1 |
Necrosis |
Minimal |
Natural Death |
Alimentary System |
Liver |
Centrilobular |
4.0 G/KG |
10 |
71 |
654 |
3 |
1 |
Necrosis |
Moderate |
Natural Death |
Alimentary System |
Liver |
Centrilobular |
4.0 G/KG |
10 |
71 |
655 |
2 |
1 |
Necrosis |
Minimal |
Natural Death |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
66 |
359 |
93 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Untreated Control |
10 |
61 |
151 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Untreated Control |
10 |
61 |
152 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Untreated Control |
10 |
61 |
153 |
93 |
1 |
Infiltration Cellular |
Mild, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Untreated Control |
10 |
61 |
155 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Untreated Control |
10 |
62 |
156 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Untreated Control |
10 |
62 |
157 |
93 |
1 |
Infiltration Cellular |
Mild, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Untreated Control |
10 |
62 |
158 |
93 |
1 |
Infiltration Cellular |
Mild, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Untreated Control |
10 |
62 |
159 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Untreated Control |
10 |
62 |
160 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
65 |
351 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
65 |
352 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
65 |
353 |
93 |
1 |
Infiltration Cellular |
Mild, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
65 |
354 |
93 |
1 |
Infiltration Cellular |
Mild, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
66 |
356 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
66 |
357 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
66 |
358 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
66 |
359 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
0.5 G/KG |
10 |
66 |
360 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1.0 G/KG |
10 |
67 |
451 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1.0 G/KG |
10 |
67 |
452 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1.0 G/KG |
10 |
67 |
453 |
93 |
1 |
Infiltration Cellular |
Mild, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1.0 G/KG |
10 |
67 |
454 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1.0 G/KG |
10 |
68 |
456 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1.0 G/KG |
10 |
68 |
457 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1.0 G/KG |
10 |
68 |
458 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1.0 G/KG |
10 |
68 |
459 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1.0 G/KG |
10 |
68 |
460 |
93 |
1 |
Infiltration Cellular |
Mild, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Liver |
|
2.0 G/KG |
10 |
69 |
553 |
4 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Natural Death |
Alimentary System |
Liver |
|
2.0 G/KG |
10 |
70 |
557 |
93 |
1 |
Infiltration Cellular |
Minimal, Mixed Cell |
Terminal Sacrifice |
Alimentary System |
Oral Mucosa |
Gingival |
0.5 G/KG |
2 |
65 |
354 |
93 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Oral Mucosa |
Gingival |
0.5 G/KG |
2 |
66 |
357 |
93 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Degeneration |
Mild |
Natural Death |
Alimentary System |
Pancreas |
|
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Degeneration |
Mild |
Natural Death |
Alimentary System |
Pancreas |
|
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Degeneration |
Mild |
Natural Death |
Alimentary System |
Pancreas |
|
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Degeneration |
Mild |
Natural Death |
Alimentary System |
Pancreas |
|
4.0 G/KG |
10 |
71 |
653 |
2 |
1 |
Degeneration |
Minimal |
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
4.0 G/KG |
10 |
72 |
657 |
2 |
1 |
Degeneration |
Minimal |
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Degeneration |
Minimal |
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
4.0 G/KG |
10 |
72 |
659 |
2 |
1 |
Degeneration |
Minimal |
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
4.0 G/KG |
10 |
72 |
660 |
2 |
1 |
Degeneration |
Minimal |
Moribund Sacrifice |
Alimentary System |
Pancreas |
|
4.0 G/KG |
10 |
71 |
651 |
2 |
1 |
Degeneration |
Minimal |
Natural Death |
Alimentary System |
Pancreas |
|
4.0 G/KG |
10 |
71 |
652 |
2 |
1 |
Degeneration |
Minimal |
Natural Death |
Alimentary System |
Pancreas |
|
4.0 G/KG |
10 |
71 |
654 |
3 |
1 |
Degeneration |
Minimal |
Natural Death |
Alimentary System |
Pancreas |
|
4.0 G/KG |
10 |
72 |
656 |
2 |
1 |
Degeneration |
Mild |
Natural Death |
Alimentary System |
Salivary Glands |
|
Untreated Control |
10 |
62 |
159 |
93 |
1 |
Infiltration Cellular |
Minimal, Mononuclear Cl |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
69 |
551 |
3 |
1 |
Inflammation |
Minimal |
Moribund Sacrifice |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
69 |
552 |
23 |
1 |
Inflammation |
Mild |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
69 |
553 |
4 |
1 |
Inflammation |
Mild |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Inflammation |
Mild |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
69 |
555 |
23 |
1 |
Inflammation |
Minimal |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Inflammation |
Mild |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Inflammation |
Moderate |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Inflammation |
Minimal |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
4.0 G/KG |
10 |
71 |
653 |
2 |
1 |
Inflammation |
Mild |
Moribund Sacrifice |
Alimentary System |
Stomach |
Forestomach |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Inflammation |
Moderate |
Moribund Sacrifice |
Alimentary System |
Stomach |
Forestomach |
4.0 G/KG |
10 |
72 |
659 |
2 |
1 |
Inflammation |
Mild |
Moribund Sacrifice |
Alimentary System |
Stomach |
Forestomach |
4.0 G/KG |
10 |
71 |
652 |
2 |
1 |
Inflammation |
Mild |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
4.0 G/KG |
10 |
71 |
654 |
3 |
1 |
Inflammation |
Minimal |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
4.0 G/KG |
10 |
71 |
655 |
2 |
1 |
Inflammation |
Minimal |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Mineralization |
Mild |
Moribund Sacrifice |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
69 |
553 |
4 |
1 |
Ulcer |
Minimal |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Ulcer |
Moderate |
Natural Death |
Alimentary System |
Stomach |
Forestomach |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Ulcer |
Minimal |
Natural Death |
Alimentary System |
Stomach |
Forestomach, Epithelium |
0.5 G/KG |
10 |
65 |
352 |
93 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
1.0 G/KG |
10 |
67 |
452 |
93 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
1.0 G/KG |
10 |
67 |
454 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
2.0 G/KG |
10 |
69 |
555 |
23 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Alimentary System |
Stomach |
Forestomach, Epithelium |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Hyperplasia |
Mild |
Natural Death |
Alimentary System |
Stomach |
Forestomach, Epithelium |
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Hyperplasia |
Mild |
Natural Death |
Alimentary System |
Stomach |
Forestomach, Epithelium |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Hyperplasia |
Moderate |
Natural Death |
Alimentary System |
Stomach |
Forestomach, Epithelium |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Hyperplasia |
Minimal |
Moribund Sacrifice |
Alimentary System |
Stomach |
Glandular |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Inflammation |
Minimal, Suppurative |
Natural Death |
Alimentary System |
Stomach |
Glandular, Epithelium |
2.0 G/KG |
10 |
70 |
557 |
93 |
1 |
Hyperplasia |
Minimal, Atypical |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
61 |
151 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
61 |
152 |
93 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
61 |
153 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
61 |
154 |
93 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
61 |
155 |
93 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
62 |
156 |
93 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
62 |
157 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
62 |
158 |
93 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
62 |
159 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
62 |
160 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
67 |
451 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
67 |
452 |
93 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
67 |
453 |
93 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
67 |
454 |
93 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
67 |
455 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
68 |
456 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
68 |
457 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
68 |
458 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
68 |
459 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
1.0 G/KG |
10 |
68 |
460 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
2.0 G/KG |
10 |
69 |
551 |
3 |
1 |
Hyperplasia |
Minimal |
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
2.0 G/KG |
10 |
69 |
552 |
23 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Adrenal Cortex |
Capsule |
2.0 G/KG |
10 |
69 |
553 |
4 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Adrenal Cortex |
Capsule |
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Adrenal Cortex |
Capsule |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Adrenal Cortex |
Capsule |
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Adrenal Cortex |
Capsule |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Adrenal Cortex |
Capsule |
2.0 G/KG |
10 |
70 |
557 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
2.0 G/KG |
10 |
70 |
558 |
93 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
4.0 G/KG |
10 |
72 |
657 |
2 |
1 |
Hyperplasia |
Minimal |
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Hyperplasia |
Minimal |
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
4.0 G/KG |
10 |
72 |
660 |
2 |
1 |
Hyperplasia |
Minimal |
Moribund Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
4.0 G/KG |
10 |
71 |
651 |
2 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Adrenal Cortex |
Capsule |
4.0 G/KG |
10 |
71 |
652 |
2 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Adrenal Cortex |
Capsule |
4.0 G/KG |
10 |
71 |
655 |
2 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Adrenal Cortex |
Capsule |
4.0 G/KG |
10 |
72 |
656 |
2 |
1 |
Hyperplasia |
Minimal |
Natural Death |
Endocrine System |
Parathyroid Gland |
|
1.0 G/KG |
10 |
67 |
451 |
93 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
|
1.0 G/KG |
10 |
68 |
459 |
93 |
1 |
Inflammation |
Minimal, Granulomatous |
Terminal Sacrifice |
Hematopoietic System |
Bone Marrow |
|
2.0 G/KG |
10 |
69 |
552 |
23 |
1 |
Atrophy |
Minimal |
Natural Death |
Hematopoietic System |
Bone Marrow |
|
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Atrophy |
Mild |
Natural Death |
Hematopoietic System |
Bone Marrow |
|
2.0 G/KG |
10 |
69 |
555 |
23 |
1 |
Atrophy |
Mild |
Natural Death |
Hematopoietic System |
Bone Marrow |
|
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Atrophy |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mandibular |
2.0 G/KG |
10 |
69 |
551 |
3 |
1 |
Necrosis |
Minimal |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mandibular |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
71 |
653 |
2 |
1 |
Necrosis |
Minimal |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
72 |
657 |
2 |
1 |
Necrosis |
Minimal |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
72 |
659 |
2 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
72 |
660 |
2 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
71 |
651 |
2 |
1 |
Necrosis |
Moderate |
Natural Death |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
71 |
652 |
2 |
1 |
Necrosis |
Minimal |
Natural Death |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
71 |
654 |
3 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
71 |
655 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mandibular |
4.0 G/KG |
10 |
72 |
656 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
2.0 G/KG |
10 |
69 |
551 |
3 |
1 |
Necrosis |
Minimal |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Necrosis |
Moderate |
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
71 |
653 |
2 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
72 |
657 |
2 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
72 |
659 |
2 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
72 |
660 |
2 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
71 |
651 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
71 |
652 |
2 |
1 |
Necrosis |
Minimal |
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
71 |
654 |
3 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
71 |
655 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
4.0 G/KG |
10 |
72 |
656 |
2 |
1 |
Necrosis |
Minimal |
Natural Death |
Hematopoietic System |
Spleen |
Lymph Follic |
2.0 G/KG |
10 |
69 |
552 |
23 |
1 |
Necrosis |
Marked |
Natural Death |
Hematopoietic System |
Spleen |
Lymph Follic |
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Necrosis |
Moderate |
Natural Death |
Hematopoietic System |
Spleen |
Lymph Follic |
2.0 G/KG |
10 |
69 |
555 |
23 |
1 |
Necrosis |
Moderate |
Natural Death |
Hematopoietic System |
Spleen |
Lymph Follic |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Spleen |
Lymph Follic |
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Necrosis |
Marked |
Natural Death |
Hematopoietic System |
Spleen |
Lymph Follic |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Necrosis |
Moderate |
Natural Death |
Hematopoietic System |
Spleen |
Lymph Follic |
4.0 G/KG |
10 |
71 |
653 |
2 |
1 |
Necrosis |
Minimal |
Moribund Sacrifice |
Hematopoietic System |
Spleen |
Lymph Follic |
4.0 G/KG |
10 |
72 |
657 |
2 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Spleen |
Lymph Follic |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Spleen |
Lymph Follic |
4.0 G/KG |
10 |
72 |
659 |
2 |
1 |
Necrosis |
Minimal |
Moribund Sacrifice |
Hematopoietic System |
Spleen |
Lymph Follic |
4.0 G/KG |
10 |
72 |
660 |
2 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Spleen |
Lymph Follic |
4.0 G/KG |
10 |
71 |
652 |
2 |
1 |
Necrosis |
Minimal |
Natural Death |
Hematopoietic System |
Spleen |
Lymph Follic |
4.0 G/KG |
10 |
72 |
656 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Thymus |
|
Untreated Control |
10 |
61 |
151 |
93 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
1.0 G/KG |
10 |
67 |
451 |
93 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
1.0 G/KG |
10 |
67 |
453 |
93 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
2.0 G/KG |
10 |
69 |
551 |
3 |
1 |
Necrosis |
Marked |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
2.0 G/KG |
10 |
69 |
552 |
23 |
1 |
Necrosis |
Marked |
Natural Death |
Hematopoietic System |
Thymus |
|
2.0 G/KG |
10 |
69 |
553 |
4 |
1 |
Necrosis |
Moderate |
Natural Death |
Hematopoietic System |
Thymus |
|
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Necrosis |
Marked |
Natural Death |
Hematopoietic System |
Thymus |
|
2.0 G/KG |
10 |
69 |
555 |
23 |
1 |
Necrosis |
Marked |
Natural Death |
Hematopoietic System |
Thymus |
|
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Necrosis |
Marked |
Natural Death |
Hematopoietic System |
Thymus |
|
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Necrosis |
Marked |
Natural Death |
Hematopoietic System |
Thymus |
|
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Necrosis |
Marked |
Natural Death |
Hematopoietic System |
Thymus |
|
2.0 G/KG |
10 |
70 |
557 |
93 |
1 |
Necrosis |
Marked |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
71 |
653 |
2 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
72 |
657 |
2 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
72 |
659 |
2 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
72 |
660 |
2 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
71 |
651 |
2 |
1 |
Necrosis |
Moderate |
Natural Death |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
71 |
652 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
71 |
654 |
3 |
1 |
Necrosis |
Marked |
Natural Death |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
71 |
655 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Hematopoietic System |
Thymus |
|
4.0 G/KG |
10 |
72 |
656 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Respiratory System |
Lung |
Arteriole |
Untreated Control |
10 |
61 |
151 |
93 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Respiratory System |
Lung |
|
2.0 G/KG |
10 |
69 |
552 |
23 |
1 |
Inflammation |
Minimal, Suppurative |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
Untreated Control |
10 |
61 |
151 |
93 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
1.0 G/KG |
10 |
67 |
453 |
93 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
69 |
551 |
3 |
1 |
Degeneration |
Moderate |
Moribund Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
69 |
552 |
23 |
1 |
Degeneration |
Mild |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
69 |
553 |
4 |
1 |
Degeneration |
Minimal |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Degeneration |
Moderate |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
69 |
555 |
23 |
1 |
Degeneration |
Moderate |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Degeneration |
Mild |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Degeneration |
Moderate |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Degeneration |
Moderate |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
70 |
557 |
93 |
1 |
Degeneration |
Moderate |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
71 |
653 |
2 |
1 |
Degeneration |
Minimal |
Moribund Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
72 |
657 |
2 |
1 |
Degeneration |
Minimal |
Moribund Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Degeneration |
Mild |
Moribund Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
72 |
659 |
2 |
1 |
Degeneration |
Mild |
Moribund Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
72 |
660 |
2 |
1 |
Degeneration |
Mild |
Moribund Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
71 |
651 |
2 |
1 |
Degeneration |
Minimal |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
71 |
652 |
2 |
1 |
Degeneration |
Minimal |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
71 |
654 |
3 |
1 |
Degeneration |
Mild |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
71 |
655 |
2 |
1 |
Degeneration |
Mild |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
4.0 G/KG |
10 |
72 |
656 |
2 |
1 |
Degeneration |
Minimal |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Inflammation |
Mild |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
70 |
557 |
93 |
1 |
Inflammation |
Mild |
Terminal Sacrifice |
Respiratory System |
Nose |
Olfactory Epi |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Metaplasia |
Mild |
Natural Death |
Respiratory System |
Nose |
Respirat Epith |
0.5 G/KG |
10 |
65 |
353 |
93 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Respirat Epith |
0.5 G/KG |
10 |
66 |
358 |
93 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Respiratory System |
Nose |
Respirat Epith |
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Inflammation |
Mild |
Natural Death |
Respiratory System |
Nose |
Respirat Epith |
4.0 G/KG |
10 |
71 |
655 |
2 |
1 |
Inflammation |
Minimal |
Natural Death |
Respiratory System |
Nose |
Respirat Epith |
0.5 G/KG |
10 |
66 |
358 |
93 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2.0 G/KG |
10 |
69 |
551 |
3 |
1 |
Necrosis |
Moderate |
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
2.0 G/KG |
10 |
69 |
552 |
23 |
1 |
Necrosis |
Mild |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
2.0 G/KG |
10 |
69 |
553 |
4 |
1 |
Necrosis |
Minimal |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
2.0 G/KG |
10 |
69 |
554 |
23 |
1 |
Necrosis |
Mild |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
2.0 G/KG |
10 |
69 |
555 |
23 |
1 |
Necrosis |
Minimal |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
2.0 G/KG |
10 |
70 |
556 |
23 |
1 |
Necrosis |
Minimal |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
2.0 G/KG |
10 |
70 |
559 |
5 |
1 |
Necrosis |
Moderate |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Necrosis |
Moderate |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
4.0 G/KG |
10 |
72 |
658 |
3 |
1 |
Necrosis |
Minimal |
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
4.0 G/KG |
10 |
72 |
659 |
2 |
1 |
Necrosis |
Mild |
Moribund Sacrifice |
Urinary System |
Kidney |
Renal Tubule |
4.0 G/KG |
10 |
71 |
652 |
2 |
1 |
Necrosis |
Moderate |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
4.0 G/KG |
10 |
71 |
655 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
4.0 G/KG |
10 |
72 |
656 |
2 |
1 |
Necrosis |
Mild |
Natural Death |
Urinary System |
Kidney |
Renal Tubule |
2.0 G/KG |
10 |
70 |
560 |
8 |
1 |
Regeneration |
Minimal |
Natural Death |
Urinary System |
Kidney |
|
Untreated Control |
10 |
61 |
151 |
93 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |