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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | bis(2-Chloroethoxy)methane |
CASRN: | ="111-91-1" |
Study Number: | C99028 |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | SKIN APPLICATION |
TDMS Number: | 9902806 |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (MG/KG) |
Control Code |
Final Body Weight (g) |
Day 4 |
165 |
600 |
|
18.1 |
Day 20 |
196 |
600 |
|
17.9 |
Day 37 |
181 |
600 |
|
20.6 |
Day 44 |
168 |
600 |
|
21.4 |
Day 72 |
176 |
600 |
|
27.5 |
Day 123 |
172 |
600 |
|
32.6 |
Day 127 |
139 |
300 |
|
26.1 |
Day 168 |
100 |
150 |
|
39.6 |
Day 226 |
153 |
600 |
|
32.2 |
Day 245 |
166 |
600 |
|
33.3 |
Day 251 |
192 |
600 |
|
38.3 |
Day 397 |
23 |
0 |
|
41.9 |
Day 420 |
171 |
600 |
|
41.9 |
Day 451 |
106 |
300 |
|
59.6 |
Day 451 |
195 |
600 |
|
40.7 |
Day 461 |
44 |
0 |
|
47.4 |
Day 486 |
164 |
600 |
|
35.1 |
Day 489 |
154 |
600 |
|
43.8 |
Day 495 |
48 |
0 |
|
37.3 |
Day 495 |
69 |
150 |
|
36.4 |
Day 499 |
35 |
0 |
|
44.6 |
Day 501 |
144 |
300 |
|
47.6 |
Day 506 |
178 |
600 |
|
57.2 |
Day 521 |
54 |
150 |
|
43.7 |
Day 522 |
187 |
600 |
|
36.3 |
Day 533 |
45 |
0 |
|
53.2 |
Day 533 |
49 |
0 |
|
42.8 |
Day 533 |
53 |
150 |
|
24.5 |
Day 533 |
142 |
300 |
|
52.2 |
Day 539 |
7 |
0 |
|
53.8 |
Day 544 |
28 |
0 |
|
52.3 |
Day 558 |
14 |
0 |
|
28.6 |
Day 568 |
170 |
600 |
|
49.2 |
Day 573 |
189 |
600 |
|
42.5 |
Day 578 |
21 |
0 |
|
43.6 |
Day 589 |
60 |
150 |
|
55.6 |
Day 611 |
70 |
150 |
|
42.6 |
Day 630 |
169 |
600 |
|
46.6 |
Day 631 |
57 |
150 |
|
27 |
Day 633 |
10 |
0 |
|
44.5 |
Day 638 |
133 |
300 |
|
25.7 |
Day 648 |
120 |
300 |
|
39.2 |
Day 648 |
182 |
600 |
|
36.7 |
Day 656 |
71 |
150 |
|
36.3 |
Day 661 |
128 |
300 |
|
59.9 |
Day 674 |
162 |
600 |
|
50.4 |
Day 678 |
167 |
600 |
|
53.3 |
Day 694 |
15 |
0 |
|
24.8 |
Day 701 |
72 |
150 |
|
27.9 |
Day 707 |
41 |
0 |
|
38.9 |
Day 712 |
79 |
150 |
|
27 |
Day 720 |
198 |
600 |
|
29 |
Day 722 |
123 |
300 |
|
38.1 |
Day 726 |
155 |
600 |
|
37.7 |
Day 727 |
78 |
150 |
|
37.9 |
Day 728 |
11 |
0 |
|
57.6 |
Day 728 |
30 |
0 |
|
57.9 |
Day 728 |
32 |
0 |
|
47.8 |
Day 728 |
33 |
0 |
|
60.8 |
Day 728 |
40 |
0 |
|
51.1 |
Day 728 |
50 |
0 |
|
45.3 |
Day 728 |
61 |
150 |
|
58.3 |
Day 728 |
64 |
150 |
|
62 |
Day 728 |
65 |
150 |
|
61.2 |
Day 728 |
87 |
150 |
|
36.7 |
Day 728 |
90 |
150 |
|
61.7 |
Day 728 |
93 |
150 |
|
37.9 |
Day 728 |
95 |
150 |
|
47 |
Day 728 |
102 |
300 |
|
53.4 |
Day 728 |
104 |
300 |
|
33.3 |
Day 728 |
110 |
300 |
|
60.8 |
Day 728 |
124 |
300 |
|
64.6 |
Day 728 |
129 |
300 |
|
56.1 |
Day 728 |
135 |
300 |
|
55.1 |
Day 728 |
140 |
300 |
|
54.7 |
Day 728 |
150 |
300 |
|
47.1 |
Day 728 |
152 |
600 |
|
62 |
Day 728 |
156 |
600 |
|
49.7 |
Day 728 |
158 |
600 |
|
43.6 |
Day 728 |
159 |
600 |
|
49.6 |
Day 728 |
177 |
600 |
|
66.3 |
Day 728 |
184 |
600 |
|
63.7 |
Day 728 |
191 |
600 |
|
42.5 |
Day 728 |
193 |
600 |
|
44.3 |
Day 728 |
200 |
600 |
|
53.9 |
Day 729 |
12 |
0 |
|
59.5 |
Day 729 |
13 |
0 |
|
43 |
Day 729 |
17 |
0 |
|
49.6 |
Day 729 |
18 |
0 |
|
59 |
Day 729 |
19 |
0 |
|
52.9 |
Day 729 |
20 |
0 |
|
55.4 |
Day 729 |
22 |
0 |
|
40.2 |
Day 729 |
31 |
0 |
|
28.8 |
Day 729 |
34 |
0 |
|
39.3 |
Day 729 |
36 |
0 |
|
41.4 |
Day 729 |
37 |
0 |
|
55.5 |
Day 729 |
5 |
0 |
|
57.1 |
Day 729 |
6 |
0 |
|
59.2 |
Day 729 |
9 |
0 |
|
53.8 |
Day 729 |
51 |
150 |
|
63.2 |
Day 729 |
52 |
150 |
|
48.3 |
Day 729 |
59 |
150 |
|
61.3 |
Day 729 |
62 |
150 |
|
54.4 |
Day 729 |
63 |
150 |
|
58.7 |
Day 729 |
67 |
150 |
|
60.2 |
Day 729 |
68 |
150 |
|
60.9 |
Day 729 |
74 |
150 |
|
42.6 |
Day 729 |
80 |
150 |
|
57.2 |
Day 729 |
83 |
150 |
|
46.6 |
Day 729 |
85 |
150 |
|
58.5 |
Day 729 |
88 |
150 |
|
33.9 |
Day 729 |
91 |
150 |
|
37.1 |
Day 729 |
105 |
300 |
|
57.2 |
Day 729 |
109 |
300 |
|
54 |
Day 729 |
111 |
300 |
|
64.6 |
Day 729 |
112 |
300 |
|
60.9 |
Day 729 |
113 |
300 |
|
66.4 |
Day 729 |
115 |
300 |
|
68.3 |
Day 729 |
118 |
300 |
|
44.7 |
Day 729 |
119 |
300 |
|
54.8 |
Day 729 |
121 |
300 |
|
62.6 |
Day 729 |
126 |
300 |
|
58.3 |
Day 729 |
127 |
300 |
|
55 |
Day 729 |
130 |
300 |
|
52 |
Day 729 |
132 |
300 |
|
63.7 |
Day 729 |
136 |
300 |
|
54.2 |
Day 729 |
137 |
300 |
|
53.2 |
Day 729 |
138 |
300 |
|
58.9 |
Day 729 |
141 |
300 |
|
49.9 |
Day 729 |
143 |
300 |
|
48.7 |
Day 729 |
146 |
300 |
|
41.8 |
Day 729 |
147 |
300 |
|
58.5 |
Day 729 |
151 |
600 |
|
58.7 |
Day 729 |
157 |
600 |
|
50.5 |
Day 729 |
161 |
600 |
|
54.6 |
Day 729 |
174 |
600 |
|
62.5 |
Day 729 |
175 |
600 |
|
60.9 |
Day 729 |
179 |
600 |
|
53 |
Day 729 |
186 |
600 |
|
57.6 |
Day 729 |
190 |
600 |
|
66.1 |
Day 729 |
197 |
600 |
|
59.3 |
Day 729 |
199 |
600 |
|
62.9 |
Day 730 |
1 |
0 |
|
38.5 |
Day 730 |
16 |
0 |
|
56.9 |
Day 730 |
2 |
0 |
|
35.2 |
Day 730 |
24 |
0 |
|
61.7 |
Day 730 |
25 |
0 |
|
49.9 |
Day 730 |
26 |
0 |
|
54 |
Day 730 |
27 |
0 |
|
61.1 |
Day 730 |
29 |
0 |
|
39.9 |
Day 730 |
3 |
0 |
|
46.9 |
Day 730 |
38 |
0 |
|
61.4 |
Day 730 |
39 |
0 |
|
49.1 |
Day 730 |
4 |
0 |
|
54.7 |
Day 730 |
42 |
0 |
|
50.1 |
Day 730 |
43 |
0 |
|
54.9 |
Day 730 |
46 |
0 |
|
58.4 |
Day 730 |
47 |
0 |
|
58.7 |
Day 730 |
8 |
0 |
|
40.9 |
Day 730 |
55 |
150 |
|
57.6 |
Day 730 |
56 |
150 |
|
61 |
Day 730 |
58 |
150 |
|
51.5 |
Day 730 |
66 |
150 |
|
59 |
Day 730 |
73 |
150 |
|
62.5 |
Day 730 |
75 |
150 |
|
39 |
Day 730 |
76 |
150 |
|
53.3 |
Day 730 |
77 |
150 |
|
56.1 |
Day 730 |
81 |
150 |
|
58 |
Day 730 |
82 |
150 |
|
65 |
Day 730 |
84 |
150 |
|
67.3 |
Day 730 |
86 |
150 |
|
31.6 |
Day 730 |
89 |
150 |
|
57.2 |
Day 730 |
92 |
150 |
|
50.9 |
Day 730 |
94 |
150 |
|
31.1 |
Day 730 |
96 |
150 |
|
62 |
Day 730 |
97 |
150 |
|
65.1 |
Day 730 |
98 |
150 |
|
57.7 |
Day 730 |
99 |
150 |
|
57.1 |
Day 730 |
101 |
300 |
|
57.2 |
Day 730 |
103 |
300 |
|
44.2 |
Day 730 |
107 |
300 |
|
44.3 |
Day 730 |
108 |
300 |
|
54.2 |
Day 730 |
114 |
300 |
|
58.3 |
Day 730 |
116 |
300 |
|
56.6 |
Day 730 |
117 |
300 |
|
64 |
Day 730 |
122 |
300 |
|
54.9 |
Day 730 |
125 |
300 |
|
51.5 |
Day 730 |
131 |
300 |
|
42.5 |
Day 730 |
134 |
300 |
|
57.3 |
Day 730 |
145 |
300 |
|
66.2 |
Day 730 |
148 |
300 |
|
61.6 |
Day 730 |
149 |
300 |
|
52.4 |
Day 730 |
160 |
600 |
|
57.4 |
Day 730 |
163 |
600 |
|
37.4 |
Day 730 |
173 |
600 |
|
61 |
Day 730 |
180 |
600 |
|
45.5 |
Day 730 |
183 |
600 |
|
54.9 |
Day 730 |
185 |
600 |
|
56.8 |
Day 730 |
188 |
600 |
|
54.8 |
Day 730 |
194 |
600 |
|
49.4 |
Abbreviations: |
NA: Not Available
|