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Short-Term Individual Animal Non Neoplastic Diagnosis
Study Information:
Chemical Name: | trans-1,2-Dichloroethylene |
CASRN: | ="156-60-5" |
Study Number: | C54591D |
Exposure Route: | DOSED FEED |
TDMS Number: | 5459110 |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Male Individual Animal Non Neoplastic Diagnoses
System |
Organ |
Site |
Treatment Group |
Number Examined |
Cage Number |
Animal Number |
Days on Study |
Lesion Found |
Lesion Name |
Lesion Qualifier |
Removal Reason |
Alimentary System |
Gallbladder |
|
Vehicle Control |
10 |
16 |
16 |
92 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Glandular |
Untreated Control |
10 |
6 |
6 |
92 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Glandular |
Untreated Control |
10 |
9 |
9 |
92 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Glandular |
50000 PPM |
10 |
66 |
66 |
92 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
Valve |
Untreated Control |
10 |
2 |
2 |
92 |
1 |
Pigmentation |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Untreated Control |
10 |
2 |
2 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
Vehicle Control |
10 |
11 |
11 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Capsule |
50000 PPM |
10 |
64 |
64 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Untreated Control |
10 |
5 |
5 |
92 |
1 |
Angiectasis |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
10 |
17 |
17 |
92 |
1 |
Angiectasis |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
10 |
20 |
20 |
92 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
50000 PPM |
10 |
67 |
67 |
92 |
1 |
Angiectasis |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
50000 PPM |
10 |
69 |
69 |
92 |
1 |
Angiectasis |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Untreated Control |
10 |
1 |
1 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Untreated Control |
10 |
10 |
10 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Untreated Control |
10 |
2 |
2 |
92 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Untreated Control |
10 |
3 |
3 |
92 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Untreated Control |
10 |
4 |
4 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Untreated Control |
10 |
5 |
5 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Untreated Control |
10 |
6 |
6 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Untreated Control |
10 |
7 |
7 |
92 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Untreated Control |
10 |
9 |
9 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
10 |
11 |
11 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
10 |
12 |
12 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
10 |
17 |
17 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
10 |
18 |
18 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
10 |
19 |
19 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
10 |
20 |
20 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
50000 PPM |
10 |
61 |
61 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
50000 PPM |
10 |
62 |
62 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
50000 PPM |
10 |
63 |
63 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
50000 PPM |
10 |
64 |
64 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
50000 PPM |
10 |
66 |
66 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
50000 PPM |
10 |
67 |
67 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
50000 PPM |
10 |
68 |
68 |
92 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
10 |
18 |
18 |
92 |
1 |
Hemorrhage |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
16 |
16 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
50000 PPM |
10 |
63 |
63 |
92 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
50000 PPM |
10 |
67 |
67 |
92 |
1 |
Inflammation |
Minimal, Focal |
Terminal Sacrifice |