Alimentary System |
Liver |
|
Vehicle Control |
10 |
41 |
244 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
42 |
247 |
92 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Liver |
|
30 mg/mL |
10 |
50 |
271 |
92 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Liver |
|
30 mg/mL |
10 |
51 |
277 |
92 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Alimentary System |
Liver |
|
30 mg/mL |
10 |
52 |
280 |
92 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Subcapsular |
Vehicle Control |
10 |
41 |
241 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Subcapsular |
Vehicle Control |
10 |
41 |
244 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Subcapsular |
Vehicle Control |
10 |
42 |
245 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Subcapsular |
Vehicle Control |
10 |
42 |
248 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Subcapsular |
30 mg/mL |
10 |
50 |
272 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Subcapsular |
30 mg/mL |
10 |
50 |
273 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
Subcapsular |
30 mg/mL |
10 |
51 |
276 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
Vehicle Control |
10 |
43 |
250 |
92 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
30 mg/mL |
10 |
52 |
279 |
92 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Endocrine System |
Islets |
Pancreatic |
30 mg/mL |
10 |
51 |
275 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Intermed |
Vehicle Control |
10 |
41 |
243 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
30 mg/mL |
10 |
50 |
274 |
92 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Clitoral Gland |
|
30 mg/mL |
10 |
52 |
280 |
92 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Ovary |
|
30 mg/mL |
10 |
52 |
280 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Uterus |
Arteriole |
3 mg/mL |
1 |
45 |
256 |
92 |
1 |
Hypertrophy |
Mild |
Terminal Sacrifice |
Genital System |
Uterus |
|
3 mg/mL |
1 |
45 |
256 |
92 |
1 |
Decidual Reaction |
Marked |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
10 |
41 |
241 |
92 |
1 |
Hyperplasia |
Minimal, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Lymph Follic |
30 mg/mL |
10 |
52 |
280 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
41 |
241 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
41 |
242 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
41 |
243 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
41 |
244 |
92 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
42 |
245 |
92 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
42 |
246 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
42 |
247 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
42 |
248 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
43 |
250 |
92 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
50 |
272 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
50 |
273 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
50 |
274 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
51 |
275 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
51 |
276 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
51 |
277 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
51 |
278 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
52 |
279 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
41 |
241 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
41 |
243 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
42 |
245 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
42 |
246 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
42 |
247 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
42 |
248 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
10 |
43 |
250 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
50 |
271 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
50 |
273 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
51 |
275 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
51 |
277 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
30 mg/mL |
10 |
51 |
278 |
92 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
41 |
242 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
10 |
41 |
243 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
30 mg/mL |
10 |
51 |
275 |
92 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
10 |
41 |
241 |
92 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |