Identification of p53 Activators in a Human Microarray Compendium with Significant Biomarker Correlation
Biomarkers predictive of molecular and toxicological effects are needed to interpret emerging high-throughput transcriptomic data streams. The TGx-DDI biomarker was compared to microarray data in a compendium derived from human cells using the Running Fisher test, a nonparametric correlation test. This dataset contains 274 biosets with a significant TGx-DDI biomarker correlation.
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|Bioset Name||Chemical||Tier||Time of Treatment (hrs)||Concentration||Study||Biosource||Biomarker (-log(p-value))||Possible Mechanism||Comments||References (PubMed ID)|