Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02741-0015-0000-2 |
Chemical Name: | Propiolactone |
CASRN: | 57-57-8 |
NTP Study Type: | Genetic Toxicology - Drosophila Germ Cell Mutagenicity |
NTP Study ID: | 409489_RT |
Study Result: | Positive |
You may also view: Sex-Linked Recessive Lethal Data for this study.
Route of Exposure | Dose ppm | Solvent | No. RTs / No. tests per sperm batch (in days of storage *) | Total No. of Translocations | Translocation Frequency (%) | |||||
---|---|---|---|---|---|---|---|---|---|---|
0-3 | 3-7 | 7-10 | 10-14 | 14-17 | 17-20 | |||||
Test Chemical | 500 | Distilled Water | 0/2329 | 0/1506 | 0/953 | 0/725 | 0/303 | 0/104 | 0/5920 | 0.00 |
1000 | Distilled Water | 0/1962 | 0/1787 | 0/1272 | 0/697 | 0/239 | 0/13 | 0/5970 | 0.00 | |
5000 | Distilled Water | 1/332 | 3/350 | 6/321 | 1/61 | 1/22 | 0/2 | 12/1088 | 1.10 | |
Days of Storage: The number of days sperm were stored in the female before testing.