Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02741-0019-0000-6 |
Chemical Name: | Propiolactone |
CASRN: | 57-57-8 |
NTP Study Type: | Genetic Toxicology - Drosophila Germ Cell Mutagenicity |
NTP Study ID: | 824474_RT |
Study Result: | Positive |
You may also view: Sex-Linked Recessive Lethal Data for this study.
Route of Exposure | Dose ppm | Solvent | No. RTs / No. tests per sperm batch (in days of storage *) | Total No. of Translocations | Translocation Frequency (%) | |||||
---|---|---|---|---|---|---|---|---|---|---|
0-3 | 3-7 | 7-10 | 10-14 | 14-17 | 17-20 | |||||
Test Chemical | 5000 | Sucrose | 0/2771 | 0/2653 | 1/2757 | 2/1460 | 2/737 | 0/0 | 5/10378 | 0.05 |
Vehicle Control | 0 | Sucrose | 0/1100 | 0/1158 | 0/969 | 0/162 | 0/59 | 0/0 | 0/3448 | 0.00 |
Days of Storage: The number of days sperm were stored in the female before testing.