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The DNTP Technical Report (TR) Level of Evidence Criteria are available here: https://ntp.niehs.nih.gov/go/baresults. In the table below this information is further delineated into three fields:

  • Level of Evidence: The overall category of evidence of carcinogenic activity for the TR, Species, Strain and Sex
  • Organ Site Call: The level of evidence supported by the specific organ site for the TR, Species, Strain and Sex. When the Organ Site Call directly supports the TR Level Of Evidence the Finding Type flag is set to “Neoplastic Lesion”. Some Organ Site Calls could support a separate call of Equivocal Evidence; this is noted in Finding Type by the flag “May Have Been Related”
  • Finding Type: Further identification of the Organ Site Call. Where this says “Neoplastic Lesion” the Organ Site Call supports the TR Level of Evidence and the Organ Site Call is the same as that of the TR. Where Finding Type says “May Have Been Related” the TR Level of Evidence for other responses led to an overall call of Clear or Some Evidence but the specified organ supports a call of Equivocal Evidence.
View results
  • Organ: All Organs
  • Level of Evidence: Positive, Clear Evidence, Some Evidence
Displays results that match exactly with the given criteria.
Exact Match Publication No. CASRN Test Article Name Species Strain Sex Route Organ Level of Evidence Organ Site Call Tumor Type/Incidence Finding Type
Yes TR-588 5694-00-8 Glycidamide Rats F344 (NCTR) Male Dosed-Water All Organs Clear Evidence Equivocal Evidence Mononuclear Cell Leukemia 21/48 26/48 27/48 27/47 31/48 May Have Been Related
Yes TR-581 7440-48-4 Cobalt Rats F344/NTac Female Inhalation All Organs Clear Evidence Clear Evidence Mononuclear Cell Leukemia 16/50 29/50 28/50 27/50 Neoplastic Lesions
Yes TR-590 1309-64-4 Antimony Trioxide Mice B6C3F1 Female Inhalation All Organs Clear Evidence Clear Evidence malignant lymphoma (7/50, 17/50, 20/50, 27/50) Neoplastic Lesions
Yes TR-563 89-82-7 Pulegone Mice B6C3F1/N Female Gavage All Organs Clear Evidence Equivocal Evidence Osteoma or osteosarcoma: 0/49 0/50 3/50 1/50 May Have Been Related
Yes TR-582 75-35-4 Vinylidene Chloride Mice B6C3F1/N Female Inhalation All Organs Clear Evidence Clear Evidence hemangioma or hemangiosarcoma 4/50 6/50 6/50 11/50 Neoplastic Lesions
Yes TR-578 90045-36-6 Ginkgo biloba extract Rats F344/N Male Gavage All Organs Some Evidence Equivocal Evidence Mononuclear Cell Leukemia 9/50, 12/50, 22/50, 21/50 May Have Been Related
Yes TR-582 75-35-4 Vinylidene Chloride Rats F344/N Female Inhalation All Organs Some Evidence Equivocal Evidence malignant mesothelioma 0/50 1/50 1/50 0/50 May Have Been Related
Yes TR-582 75-35-4 Vinylidene Chloride Rats F344/N Female Inhalation All Organs Some Evidence Some Evidence mononuclear cell leukemia 10/50 11/50 13/50 25/50 Neoplastic Lesions
Yes TR-582 75-35-4 Vinylidene Chloride Rats F344/N Male Inhalation All Organs Clear Evidence Clear Evidence malignant mesothelioma 1/50 12/50 28/50 23/50 Neoplastic Lesions
Yes TR-583 71133-14-7 Water disinfection byproducts (Bromodichloroacetic Acid) Rats F344/NTac Male Dosed-Water All Organs Clear Evidence Clear Evidence malignant mesothelioma 1/50 12/50 18/50 37/50 Neoplastic Lesions
Yes TR-587 79-94-7 Tetrabromobisphenol A Mice B6C3F1/N Male Gavage All Organs Some Evidence Equivocal Evidence (Hemangiosarcoma) 1/50 5/50 8/50 May Have Been Related
Yes TR-558 14047-09-7 3,3',4,4'-Tetrachloroazobenzene Mice B6C3F1/N Female Gavage All Organs Clear Evidence Equivocal Evidence Malignant Lymphoma: 2/50 5/50 8/50 7/50 May Have Been Related
Yes TR-588 5694-00-8 Glycidamide Rats F344 (NCTR) Female Dosed-Water All Organs Clear Evidence Clear Evidence Mononuclear Cell Leukemia 14/48 11/48 21/48 19/48 27/48 Neoplastic Lesions