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The DNTP Technical Report (TR) Level of Evidence Criteria are available here: https://ntp.niehs.nih.gov/go/baresults. In the table below this information is further delineated into three fields:

Level of Evidence: The overall category of evidence of carcinogenic activity for the TR, Species, Strain and Sex
Organ Site Call: The level of evidence supported by the specific organ site for the TR, Species, Strain and Sex. When the Organ Site Call directly supports the TR Level Of Evidence the Finding Type flag is set to “Neoplastic Lesion”. Some Organ Site Calls could support a separate call of Equivocal Evidence; this is noted in Finding Type by the flag “May Have Been Related”
Finding Type: Further identification of the Organ Site Call. Where this says “Neoplastic Lesion” the Organ Site Call supports the TR Level of Evidence and the Organ Site Call is the same as that of the TR. Where Finding Type says “May Have Been Related” the TR Level of Evidence for other responses led to an overall call of Clear or Some Evidence but the specified organ supports a call of Equivocal Evidence.

Displays results that match exactly with the given criteria.
Exact Match	Publication No.	CASRN	Test Article Name	Species	Strain	Sex	Route	Organ	Level of Evidence	Organ Site Call	Tumor Type/Incidence	Finding Type
Yes	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	All Organs	Clear Evidence	Equivocal Evidence	Mononuclear Cell Leukemia 21/48 26/48 27/48 27/47 31/48	May Have Been Related
Yes	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Female	Inhalation	All Organs	Clear Evidence	Clear Evidence	Mononuclear Cell Leukemia 16/50 29/50 28/50 27/50	Neoplastic Lesions
Yes	TR-590	1309-64-4	Antimony Trioxide	Mice	B6C3F1	Female	Inhalation	All Organs	Clear Evidence	Clear Evidence	malignant lymphoma (7/50, 17/50, 20/50, 27/50)	Neoplastic Lesions
Yes	TR-563	89-82-7	Pulegone	Mice	B6C3F1/N	Female	Gavage	All Organs	Clear Evidence	Equivocal Evidence	Osteoma or osteosarcoma: 0/49 0/50 3/50 1/50	May Have Been Related
Yes	TR-582	75-35-4	Vinylidene Chloride	Mice	B6C3F1/N	Female	Inhalation	All Organs	Clear Evidence	Clear Evidence	hemangioma or hemangiosarcoma 4/50 6/50 6/50 11/50	Neoplastic Lesions
Yes	TR-578	90045-36-6	Ginkgo biloba extract	Rats	F344/N	Male	Gavage	All Organs	Some Evidence	Equivocal Evidence	Mononuclear Cell Leukemia 9/50, 12/50, 22/50, 21/50	May Have Been Related
Yes	TR-582	75-35-4	Vinylidene Chloride	Rats	F344/N	Female	Inhalation	All Organs	Some Evidence	Equivocal Evidence	malignant mesothelioma 0/50 1/50 1/50 0/50	May Have Been Related
Yes	TR-582	75-35-4	Vinylidene Chloride	Rats	F344/N	Female	Inhalation	All Organs	Some Evidence	Some Evidence	mononuclear cell leukemia 10/50 11/50 13/50 25/50	Neoplastic Lesions
Yes	TR-582	75-35-4	Vinylidene Chloride	Rats	F344/N	Male	Inhalation	All Organs	Clear Evidence	Clear Evidence	malignant mesothelioma 1/50 12/50 28/50 23/50	Neoplastic Lesions
Yes	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Rats	F344/NTac	Male	Dosed-Water	All Organs	Clear Evidence	Clear Evidence	malignant mesothelioma 1/50 12/50 18/50 37/50	Neoplastic Lesions
Yes	TR-587	79-94-7	Tetrabromobisphenol A	Mice	B6C3F1/N	Male	Gavage	All Organs	Some Evidence	Equivocal Evidence	(Hemangiosarcoma) 1/50 5/50 8/50	May Have Been Related
Yes	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	All Organs	Clear Evidence	Equivocal Evidence	Malignant Lymphoma: 2/50 5/50 8/50 7/50	May Have Been Related
Yes	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Female	Dosed-Water	All Organs	Clear Evidence	Clear Evidence	Mononuclear Cell Leukemia 14/48 11/48 21/48 19/48 27/48	Neoplastic Lesions

Displays all results in TRs which have data that match the given criteria.
Exact Match	Publication No.	CASRN	Test Article Name	Species	Strain	Sex	Route	Organ	Level of Evidence	Organ Site Call	Tumor Type/Incidence	Finding Type
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Adrenal Gland Cortex	Clear Evidence	Equivocal Evidence	Adenoma 1/50 1/50 3/50 4/49	May Have Been Related
Yes	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	All Organs	Clear Evidence	Equivocal Evidence	Malignant Lymphoma: 2/50 5/50 8/50 7/50	May Have Been Related
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Forestomach	Clear Evidence	Clear Evidence	Squamous cell carcinoma 0/50 1/50 1/50 4/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Male	Gavage	Forestomach	Clear Evidence	Clear Evidence	Squamous cell carcinoma 0/50 1/50 1/49 3/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Forestomach	Clear Evidence	Clear Evidence	Squamous cell papilloma or carcinoma 0/50 1/50 0/50 4/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Liver	Clear Evidence	Clear Evidence	Cholangiocarcinoma 1/50 1/50 1/49 3/49	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Liver	Clear Evidence	Clear Evidence	Cholangiocarcinoma 0/50 4/50 4/50 6/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Lung	Clear Evidence	Clear Evidence	Alveolar/bronchiolar adenoma or carcinoma 0/49 2/50 1/50 4/50 alveolar/bronchiolar adenoma or carcinoma 3/49 8/50 5/50 10/50 cystic keratinizing epithelioma 0/49 0/50 0/50 2/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Male	Gavage	Lung	Clear Evidence	Clear Evidence	Alveolar/bronchiolar adenoma 5/50 16/50 12/49 6/50 alveolar/bronchiolar adenoma or carcinoma 7/50 17/50 15/49 6/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Lung	Clear Evidence	Clear Evidence	Cystic keratinizing epithelioma 0/50 6/50 26/49 39/49	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Lung	Clear Evidence	Clear Evidence	Cystic keratinizing epithelioma 0/50 14/50 31/50 37/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Oral Cavity	Clear Evidence	Clear Evidence	Mucosa: Gingival squamous cell carcinoma 0/50 0/50 4/50 6/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Oral Cavity	Clear Evidence	Clear Evidence	Mucosa: Gingival squamous cell carcinoma 1/50 5/50 4/50 5/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Skin	Clear Evidence	Clear Evidence	Fibrosarcoma 1/50 6/50 5/50 8/50 fibrosarcoma or malignant schwannoma 2/50 8/50 7/50 12/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Thoracic Cavity	Clear Evidence	Equivocal Evidence	Malignant Schwannoma: 0/50 0/50 1/50 3/50	May Have Been Related
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Thyroid Gland Follicular Cell	Clear Evidence	Clear Evidence	adenoma 0/50 3/50 4/50 4/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Ureter	Clear Evidence	Equivocal Evidence	Transitional epithelial carcinoma: 0/0 0/1 0/0 1/2	May Have Been Related
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Male	Gavage	Ureter	Clear Evidence	Equivocal Evidence	Transitional epithelial carcinoma: 0/43 0/45 1/47 0/50	May Have Been Related
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Urinary System	Clear Evidence	Clear Evidence	Urethra: Transitional epithelial gland carcinoma 0/50 0/50 0/50 2/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Male	Gavage	Urinary System	Clear Evidence	Clear Evidence	Urethra: Transitional epithelial gland carcinoma 0/50 32/50 46/49 49/50	Neoplastic Lesions
No	TR-590	1309-64-4	Antimony Trioxide	Rats	Wistar Han	Female	Inhalation	Adrenal Gland Medulla	Some Evidence	Some Evidence	benign pheochromocytoma (0/49, 2/49, 2/49, 6/50); benign or malignant pheochromocytoma (0/49, 2/49, 2/49, 7/50)	Neoplastic Lesions
No	TR-590	1309-64-4	Antimony Trioxide	Rats	Wistar Han	Male	Inhalation	Adrenal Gland Medulla	Some Evidence	Some Evidence	benign pheochromocytoma (1/49, 0/50, 2/49, 7/50)	Neoplastic Lesions
Yes	TR-590	1309-64-4	Antimony Trioxide	Mice	B6C3F1	Female	Inhalation	All Organs	Clear Evidence	Clear Evidence	malignant lymphoma (7/50, 17/50, 20/50, 27/50)	Neoplastic Lesions
No	TR-590	1309-64-4	Antimony Trioxide	Rats	Wistar Han	Female	Inhalation	Lung	Some Evidence	Equivocal Evidence	cystic keratinizing epithelioma or squamous cell carcinoma (0/50, 0/50, 0/50, 3/50)	May Have Been Related
No	TR-590	1309-64-4	Antimony Trioxide	Mice	B6C3F1	Female	Inhalation	Lung	Clear Evidence	Clear Evidence	alveolar/bronchiolar adenoma (1/50, 10/50, 19/50, 8/50); alveolar/bronchiolar carcinoma (2/50, 14/50, 11/50, 11/50); alveolar/bronchiolar adenoma or carcinoma (3/50, 22/50, 27/50, 18/50)	Neoplastic Lesions
No	TR-590	1309-64-4	Antimony Trioxide	Mice	B6C3F1	Male	Inhalation	Lung	Clear Evidence	Clear Evidence	alveolar/bronchiolar carcinoma (4/50, 18/50, 20/50, 27/50)	Neoplastic Lesions
No	TR-590	1309-64-4	Antimony Trioxide	Rats	Wistar Han	Female	Inhalation	Lung	Some Evidence	Some Evidence	alveolar/bronchiolar adenoma (0/50, 2/50, 6/50, 5/50)	Neoplastic Lesions
No	TR-590	1309-64-4	Antimony Trioxide	Rats	Wistar Han	Male	Inhalation	Lung	Some Evidence	Some Evidence	alveolar/bronchiolar adenoma (3/50, 4/50, 6/50, 8/50); alveolar/bronchiolar adenoma or carcinoma (3/50, 4/50, 8/50, 8/50)	Neoplastic Lesions
No	TR-590	1309-64-4	Antimony Trioxide	Mice	B6C3F1	Female	Inhalation	Skin	Clear Evidence	Equivocal Evidence	squamous cell carcinoma (0/50, 0/50, 0/50, 2/50)	May Have Been Related
No	TR-590	1309-64-4	Antimony Trioxide	Mice	B6C3F1	Male	Inhalation	Skin	Clear Evidence	Clear Evidence	fibrous histiocytoma (0/50, 1/50, 1/50, 4/50); fibrous histiocytoma or fibrosarcoma (0/50, 1/50, 3/50, 4/50)	Neoplastic Lesions
No	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Female	Inhalation	Adrenal Gland Medulla	Clear Evidence	Clear Evidence	benign pheochromocytoma 6/50 12/50 22/50 36/50 malignant pheochromocytoma 0/50 2/50 3/50 11/50 benign or malignant pheochromocytoma 6/50 13/50 23/50 40/50	Neoplastic Lesions
No	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Male	Inhalation	Adrenal Gland Medulla	Clear Evidence	Clear Evidence	benign pheochromocytoma 15/50 23/50 37/50 34/50 malignant pheochromocytoma 2/50 2/50 9/50 16/50 benign or malignant pheochromocytoma 17/50 23/50 38/50 41/50	Neoplastic Lesions
Yes	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Female	Inhalation	All Organs	Clear Evidence	Clear Evidence	Mononuclear Cell Leukemia 16/50 29/50 28/50 27/50	Neoplastic Lesions
No	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Male	Inhalation	Kidney	Clear Evidence	Equivocal Evidence	adenoma or carcinoma (standard evaluation) 0/50 1/50 0/50 4/50 (standard and extended evaluations combined) 3/50 1/50 1/50 7/50	May Have Been Related
No	TR-581	7440-48-4	Cobalt	Mice	B6C3F1/N	Female	Inhalation	Lung	Clear Evidence	Equivocal Evidence	alveolar/bronchiolar adenoma 3/49 9/50 8/50 10/50 alveolar/bronchiolar carcinoma 5/49 25/50 38/50 43/50 alveolar/bronchiolar adenoma or carcinoma 8/49 30/50 41/50 45/50	May Have Been Related
No	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Male	Inhalation	Lung	Clear Evidence	Equivocal Evidence	cystic keratinizing epithelioma 0/50 1/50 0/50 1/50	May Have Been Related
No	TR-581	7440-48-4	Cobalt	Mice	B6C3F1/N	Male	Inhalation	Lung	Clear Evidence	Clear Evidence	alveolar/bronchiolar adenoma 7/50 11/49 15/50 3/50 alveolar/bronchiolar carcinoma 11/50 38/49 42/50 46/50 alveolar/bronchiolar adenoma or carcinoma 16/50 41/49 43/50 47/50	Neoplastic Lesions
No	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Female	Inhalation	Lung	Clear Evidence	Clear Evidence	alveolar/bronchiolar adenoma 2/50 7/50 9/50 13/50 alveolar/bronchiolar carcinoma 0/50 9/50 17/50 30/50 alveolar/bronchiolar adenoma or carcinoma 2/50 15/50 20/50 38/50 cystic keratinizing epithelioma 0/50 4/50 1/50 2/50	Neoplastic Lesions
No	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Male	Inhalation	Lung	Clear Evidence	Clear Evidence	alveolar/bronchiolar adenoma 2/50 10/50 10/50 14/50 alveolar/bronchiolar carcinoma 0/50 16/50 34/50 36/50 alveolar/bronchiolar adenoma or carcinoma 2/50 25/50 39/50 44/50	Neoplastic Lesions
No	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Female	Inhalation	Pancreas Islet Cell	Clear Evidence	Equivocal Evidence	carcinoma 1/50 0/50 0/50 3/50	May Have Been Related
No	TR-581	7440-48-4	Cobalt	Rats	F344/NTac	Male	Inhalation	Pancreas Islet Cell	Clear Evidence	Clear Evidence	adenoma or carcinoma 2/50 2/50 10/48 9/49	Neoplastic Lesions
Yes	TR-578	90045-36-6	Ginkgo biloba extract	Rats	F344/N	Male	Gavage	All Organs	Some Evidence	Equivocal Evidence	Mononuclear Cell Leukemia 9/50, 12/50, 22/50, 21/50	May Have Been Related
No	TR-578	90045-36-6	Ginkgo biloba extract	Rats	F344/N	Male	Gavage	Liver	Some Evidence	Equivocal Evidence	hepatocellular adenoma 0/50, 3/50, 3/50, 0/50	May Have Been Related
No	TR-578	90045-36-6	Ginkgo biloba extract	Mice	B6C3F1/N	Female	Gavage	Liver	Clear Evidence	Clear Evidence	hepatocellular adenoma 17/50, 37/50, 41/50, 48/50; hepatocellular carcinoma 9/50, 10/50, 15/50, 44/50; hepatoblastoma 1/50, 1/50, 8/50, 11/50	Neoplastic Lesions
No	TR-578	90045-36-6	Ginkgo biloba extract	Mice	B6C3F1/N	Male	Gavage	Liver	Clear Evidence	Clear Evidence	hepatocellular carcinoma 22/50, 31/50, 41/50, 47/50; hepatoblastoma 3/50, 28/50, 36/50, 38/50	Neoplastic Lesions
No	TR-578	90045-36-6	Ginkgo biloba extract	Rats	F344/N	Female	Gavage	Nasal Cavity	Some Evidence	Equivocal Evidence	respiratory epithelium, adenoma 0/49, 0/49, 2/50, 0/46	May Have Been Related
No	TR-578	90045-36-6	Ginkgo biloba extract	Mice	B6C3F1/N	Male	Gavage	Thyroid Gland Follicular Cell	Clear Evidence	Clear Evidence	adenoma 0/50, 0/50, 2/50, 2/50	Neoplastic Lesions
No	TR-578	90045-36-6	Ginkgo biloba extract	Rats	F344/N	Female	Gavage	Thyroid Gland Follicular Cell	Some Evidence	Some Evidence	adenoma 1/49, 0/50, 3/49, 1/49; follicular cell, carcinoma 0/49, 0/50, 1/49, 1/49	Neoplastic Lesions
No	TR-578	90045-36-6	Ginkgo biloba extract	Rats	F344/N	Male	Gavage	Thyroid Gland Follicular Cell	Some Evidence	Some Evidence	adenoma 2/50, 1/50, 3/49, 5/45	Neoplastic Lesions
Yes	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	All Organs	Clear Evidence	Equivocal Evidence	Mononuclear Cell Leukemia 21/48 26/48 27/48 27/47 31/48	May Have Been Related
Yes	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Female	Dosed-Water	All Organs	Clear Evidence	Clear Evidence	Mononuclear Cell Leukemia 14/48 11/48 21/48 19/48 27/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Female	Dosed-Water	Clitoral Gland	Clear Evidence	Clear Evidence	carcinoma 4/48 6/48 7/48 11/48 14/47	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	Epididymis	Clear Evidence	Clear Evidence	malignant mesothelioma 0/48 1/45 3/48 10/47 17/47	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	Epididymis or Testis	Clear Evidence	Clear Evidence	malignant mesothelioma 0/48 1/48 3/48 10/47 17/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Female	Dosed-Water	Forestomach	Clear Evidence	Clear Evidence	squamous cell papilloma 1/45 1/45 1/47 5/45 9/44	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Male	Dosed-Water	Forestomach	Clear Evidence	Clear Evidence	squamous cell papilloma 0/47 2/45 3/48 2/45 10/41 squamous cell carcinoma 0/47 0/45 0/48 0/45 2/41 squamous cell papilloma or carcinoma 0/47 2/45 3/48 2/45 12/41	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Female	Dosed-Water	Forestomach	Clear Evidence	Clear Evidence	squamous cell papilloma 0/48 1/48 0/48 0/47 3/46	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Female	Dosed-Water	Harderian Gland	Clear Evidence	Clear Evidence	adenoma 2/45 19/47 20/47 24/46 40/46	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Male	Dosed-Water	Harderian Gland	Clear Evidence	Clear Evidence	adenoma 3/47 17/47 23/47 32/46 42/47	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	Heart	Clear Evidence	Clear Evidence	malignant schwannoma 2/48 3/48 3/48 7/47 8/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Female	Dosed-Water	Lung	Clear Evidence	Clear Evidence	alveolar/bronchiolar adenoma 3/46 5/48 3/47 7/47 9/44	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Male	Dosed-Water	Lung	Clear Evidence	Clear Evidence	alveolar/bronchiolar adenoma 0/47 7/46 7/47 13/47 17/47	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Female	Dosed-Water	Mammary Gland	Clear Evidence	Clear Evidence	adenoacanthoma 0/45 0/48 0/47 1/47 8/45 adenocarcinoma 1/45 1/48 2/47 9/47 11/45 adenoacanthoma or adenocarcinoma 1/45 1/48 2/47 9/47 18/45	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Female	Dosed-Water	Mammary Gland	Clear Evidence	Clear Evidence	fibroadenoma 16/48 26/48 35/48 33/48 36/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Female	Dosed-Water	Oral Cavity	Clear Evidence	Clear Evidence	Tongue: squamous cell papilloma 0/48 1/48 0/48 1/48 0/48 squamous cell carcinoma 0/48 0/48 0/48 0/48 1/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Female	Dosed-Water	Oral Cavity	Clear Evidence	Clear Evidence	Oral mucosa: squamous cell papilloma 1/48 1/48 2/48 0/48 4/48 squamous cell carcinoma 0/48 0/48 0/48 1/48 2/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Female	Dosed-Water	Oral Cavity	Clear Evidence	Clear Evidence	Oral mucosa or tongue: squamous cell papilloma or carcinoma 1/48 2/48 2/48 2/48 7/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	Oral Cavity	Clear Evidence	Clear Evidence	Oral mucosa: squamous cell papilloma 1/48 1/48 0/48 2/47 3/48 squamous cell carcinoma 1/48 0/48 1/48 1/47 0/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	Oral Cavity	Clear Evidence	Clear Evidence	Oral mucosa or tongue: squamous cell papilloma or carcinoma 2/48 2/48 2/48 3/47 7/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	Oral Cavity	Clear Evidence	Clear Evidence	Tongue: squamous cell papilloma 0/48 1/48 0/48 1/47 4/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Female	Dosed-Water	Ovary	Clear Evidence	Equivocal Evidence	granulosa cell tumor – benign or malignant 0/45 0/47 0/47 3/46 3/44	May Have Been Related
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Female	Dosed-Water	Skin	Clear Evidence	Clear Evidence	fibrosarcoma 0/45 1/48 2/47 2/47 9/45 sarcoma 0/45 0/48 1/47 3/47 3/45 fibrosarcoma or sarcoma 0/45 1/48 3/47 5/47 12/45	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Mice	MV	Male	Dosed-Water	Skin	Clear Evidence	Clear Evidence	squamous cell papilloma 0/47 1/48 2/47 1/47 8/46 squamous cell carcinoma 0/47 0/48 0/47 0/47 2/46 squamous cell papilloma or carcinoma 0/47 1/48 2/47 1/47 9/46	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	Testis	Clear Evidence	Clear Evidence	malignant mesothelioma 0/48 1/47 3/48 6/47 13/48	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Female	Dosed-Water	Thyroid Gland Follicular Cell	Clear Evidence	Clear Evidence	adenoma 0/48 3/48 3/46 1/46 5/47 follicular cell carcinoma 0/48 0/48 2/46 3/46 3/47 follicular cell adenoma or carcinoma 0/48 3/48 5/46 4/46 8/47	Neoplastic Lesions
No	TR-588	5694-00-8	Glycidamide	Rats	F344 (NCTR)	Male	Dosed-Water	Thyroid Gland Follicular Cell	Clear Evidence	Clear Evidence	adenoma 2/47 1/42 3/48 3/47 8/46 follicular cell carcinoma 0/47 2/42 3/48 1/47 5/46 follicular cell adenoma or carcinoma 2/47 3/42 6/48 4/47 13/46	Neoplastic Lesions
Yes	TR-563	89-82-7	Pulegone	Mice	B6C3F1/N	Female	Gavage	All Organs	Clear Evidence	Equivocal Evidence	Osteoma or osteosarcoma: 0/49 0/50 3/50 1/50	May Have Been Related
No	TR-563	89-82-7	Pulegone	Mice	B6C3F1/N	Female	Gavage	Liver	Clear Evidence	Clear Evidence	Hepatocellular: Adenoma 13/49 15/50 13/50 27/50 adenoma, carcinoma or hepatoblastoma 17/49 15/50 15/50 33/50	Neoplastic Lesions
No	TR-563	89-82-7	Pulegone	Mice	B6C3F1/N	Male	Gavage	Liver	Clear Evidence	Clear Evidence	Hepatocellular: Adenoma 22/50 31/50 35/50 28/50 adenoma, carcinoma, or hepatoblastoma 29/50 37/50 42/50 36/50	Neoplastic Lesions
No	TR-563	89-82-7	Pulegone	Rats	F344/N	Female	Gavage	Urinary Bladder	Some Evidence	Some Evidence	Papilloma 0/50 0/49 1/50 3/47 papilloma or carcinoma 0/50 0/49 1/50 5/47	Neoplastic Lesions
Yes	TR-587	79-94-7	Tetrabromobisphenol A	Mice	B6C3F1/N	Male	Gavage	All Organs	Some Evidence	Equivocal Evidence	(Hemangiosarcoma) 1/50 5/50 8/50	May Have Been Related
No	TR-587	79-94-7	Tetrabromobisphenol A	Mice	B6C3F1/N	Male	Gavage	Intestines (Large)	Some Evidence	Equivocal Evidence	(cecum or colon) adenoma or carcinoma 0/50 0/50 3/50	May Have Been Related
No	TR-587	79-94-7	Tetrabromobisphenol A	Mice	B6C3F1/N	Male	Gavage	Liver	Some Evidence	Some Evidence	hepatoblastoma 2/50 11/50 8/50	Neoplastic Lesions
No	TR-587	79-94-7	Tetrabromobisphenol A	Rats	Wistar Han	Male	Gavage	Testis	Equivocal Evidence	Equivocal Evidence	interstitial cell, adenoma 0/50 0/50 1/50 3/50	May Have Been Related
No	TR-587	79-94-7	Tetrabromobisphenol A	Rats	Wistar Han	Female	Gavage	Uterus	Clear Evidence	Clear Evidence	adenoma (original transverse review) 0/50 0/50 3/50 4/50 adenocarcinoma (original transverse review) 3/50 3/50 8/50 9/50 )original transverse and residual longitudinal reviews, combined) 4/50 10/50 15/50 16/50 malignant mixed Müllerian tumor (original transverse review) 0/50 4/50 0/50 2/50 adenoma, adenocarcinoma, or malignant mixed Müllerian tumor (original transverse review) 3/50 7/50 11/50 13/50 )original transverse and residual longitudinal reviews, combined) 6/50 11/50 16/50 19/50	Neoplastic Lesions
Yes	TR-582	75-35-4	Vinylidene Chloride	Rats	F344/N	Female	Inhalation	All Organs	Some Evidence	Equivocal Evidence	malignant mesothelioma 0/50 1/50 1/50 0/50	May Have Been Related
Yes	TR-582	75-35-4	Vinylidene Chloride	Mice	B6C3F1/N	Female	Inhalation	All Organs	Clear Evidence	Clear Evidence	hemangioma or hemangiosarcoma 4/50 6/50 6/50 11/50	Neoplastic Lesions
Yes	TR-582	75-35-4	Vinylidene Chloride	Rats	F344/N	Male	Inhalation	All Organs	Clear Evidence	Clear Evidence	malignant mesothelioma 1/50 12/50 28/50 23/50	Neoplastic Lesions
Yes	TR-582	75-35-4	Vinylidene Chloride	Rats	F344/N	Female	Inhalation	All Organs	Some Evidence	Some Evidence	mononuclear cell leukemia 10/50 11/50 13/50 25/50	Neoplastic Lesions
No	TR-582	75-35-4	Vinylidene Chloride	Mice	B6C3F1/N	Female	Inhalation	Intestines (Small)	Clear Evidence	Equivocal Evidence	(Duodenum, Jejunum, or Ileum): carcinoma 1/50 1/50 1/50 3/50	May Have Been Related
No	TR-582	75-35-4	Vinylidene Chloride	Mice	B6C3F1/N	Male	Inhalation	Kidney	Clear Evidence	Clear Evidence	renal tubule adenoma 0/50 5/50 19/50 10/50 renal tubule carcinoma 0/50 7/50 31/50 18/50 renal tubule adenoma or carcinoma 0/50 11/50 37/50 27/50	Neoplastic Lesions
No	TR-582	75-35-4	Vinylidene Chloride	Rats	F344/N	Male	Inhalation	Kidney	Clear Evidence	Clear Evidence	renal tubule carcinoma 0/50 2/50 1/49 1/50	Neoplastic Lesions
No	TR-582	75-35-4	Vinylidene Chloride	Mice	B6C3F1/N	Male	Inhalation	Liver	Clear Evidence	Equivocal Evidence	hepatocholangiocarcionoma 1/50 2/50 2/50 3/50	May Have Been Related
No	TR-582	75-35-4	Vinylidene Chloride	Mice	B6C3F1/N	Female	Inhalation	Liver	Clear Evidence	Clear Evidence	hepatocellular adenoma 25/50 21/50 36/50 29/50 hepatocellular carcinoma 8/50 14/50 12/50 17/50 hepatocellular adenoma or carcinoma 28/50 30/50 37/50 38/50 hepatocholangiocarcinoma 0/50 1/50 1/50 2/50	Neoplastic Lesions
No	TR-582	75-35-4	Vinylidene Chloride	Mice	B6C3F1/N	Female	Inhalation	Lung	Clear Evidence	Equivocal Evidence	alveolar/bronchiolar carcinoma 1/50 2/50 7/50 5/49	May Have Been Related
No	TR-582	75-35-4	Vinylidene Chloride	Rats	F344/N	Male	Inhalation	Nasal Cavity	Clear Evidence	Clear Evidence	respiratory epithelium, adenoma 0/49 0/50 1/50 4/50	Neoplastic Lesions
No	TR-582	75-35-4	Vinylidene Chloride	Rats	F344/N	Female	Inhalation	Thyroid Gland C-Cell	Some Evidence	Some Evidence	adenoma 3/50 4/50 6/48 11/50; carcinoma 0/50 6/50 2/48 2/50 adenoma or carcinoma 3/50 10/50 8/48 13/50	Neoplastic Lesions
Yes	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Rats	F344/NTac	Male	Dosed-Water	All Organs	Clear Evidence	Clear Evidence	malignant mesothelioma 1/50 12/50 18/50 37/50	Neoplastic Lesions
No	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Rats	F344/NTac	Female	Dosed-Water	Brain	Clear Evidence	Equivocal Evidence	glioma or oligodendroglioma (original and extended evaluations combined): 0/50 1/50 3/50 1/50	May Have Been Related
No	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Rats	F344/NTac	Male	Dosed-Water	Brain	Clear Evidence	Equivocal Evidence	glioma or oligodendroglioma (original and extended evaluations combined): 0/50 1/50 4/50 3/50	May Have Been Related
No	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Mice	B6C3F1/N	Male	Dosed-Water	Harderian Gland	Clear Evidence	Clear Evidence	adenoma 6/50 11/50 14/49 19/51 adenoma or carcinoma 6/50 11/50 14/49 20/51	Neoplastic Lesions
No	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Mice	B6C3F1/N	Female	Dosed-Water	Liver	Clear Evidence	Clear Evidence	hepatocellular adenoma 33/49 42/50 42/49 44/50 hepatocellular carcinoma 9/49 17/50 22/49 26/50 hepatoblastoma 0/49 1/50 4/49 6/50 hepatocellular adenoma, hepatocellular carcinoma, or hepatoblastoma 36/49 44/50 43/49 46/50	Neoplastic Lesions
No	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Mice	B6C3F1/N	Male	Dosed-Water	Liver	Clear Evidence	Clear Evidence	hepatocellular carcinoma 12/50 22/50 27/49 39/51 hepatoblastoma 4/50 24/50 40/49 34/51	Neoplastic Lesions
No	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Rats	F344/NTac	Female	Dosed-Water	Mammary Gland	Clear Evidence	Clear Evidence	fibroadenoma 28/50 47/50 47/50 39/50 carcinoma 0/50 1/50 3/50 8/50 fibroadenoma, adenoma, or carcinoma 28/50 47/50 48/50 42/50	Neoplastic Lesions
No	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Rats	F344/NTac	Male	Dosed-Water	Oral Cavity	Clear Evidence	Equivocal Evidence	(oral mucosa and tongue): squamous cell papilloma or squamous cell carcinoma 1/50 0/50 3/50 3/50	May Have Been Related
No	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Rats	F344/NTac	Male	Dosed-Water	Skin	Clear Evidence	Clear Evidence	(subcutaneous tissue): fibroma 4/50 6/50 10/50 15/50	Neoplastic Lesions
No	TR-583	71133-14-7	Water disinfection byproducts (Bromodichloroacetic Acid)	Rats	F344/NTac	Male	Dosed-Water	Skin	Clear Evidence	Clear Evidence	squamous cell papilloma, keratoacanthoma, sebaceous gland adenoma, basal cell adenoma, basal cell carcinoma, or squamous cell carcinoma 9/50 7/50 15/50 21/50	Neoplastic Lesions