No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Clitoral Gland
|
Clear Evidence |
Clear Evidence |
carcinoma 1/4 6/48 12/47 3/48 8/47
|
Neoplastic Lesions
|
Yes
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Epididymis
|
Clear Evidence |
Clear Evidence |
malignant mesothelioma 2/48 2/48 1/48 5/48 8/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Epididymis or Testis
|
Clear Evidence |
Clear Evidence |
malignant mesothelioma 2/48 2/48 1/48 5/48 8/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Mice |
MV |
Female |
Dosed-Water |
Forestomach
|
Clear Evidence |
Clear Evidence |
squamous cell papilloma 4/46 0/46 2/48 5/45 8/42
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Mice |
MV |
Male |
Dosed-Water |
Forestomach
|
Clear Evidence |
Clear Evidence |
squamous cell papilloma 0/46 2/45 2/46 6/47 6/44 squamous cell carcinoma 0/46 0/45 0/46 1/47 2/44 squamous cell papilloma or carcinoma 0/46 2/45 2/46 7/47 8/44
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Mice |
MV |
Female |
Dosed-Water |
Harderian Gland
|
Clear Evidence |
Clear Evidence |
adenoma 0/45 8/44 20/48 32/47 31/43
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Mice |
MV |
Male |
Dosed-Water |
Harderian Gland
|
Clear Evidence |
Clear Evidence |
adenoma 2/46 13/46 27/47 36/47 39/47 adenocarcinoma 0/46 0/46 0/47 1/47 1/47 adenoma or adenocarcinoma 2/46 13/46 27/47 37/47 39/47
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Heart
|
Clear Evidence |
Clear Evidence |
malignant Schwannoma 2/48 1/48 0/48 2/48 4/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Heart
|
Clear Evidence |
Clear Evidence |
malignant Schwannoma 1/48 2/48 3/48 4/48 6/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Liver
|
Clear Evidence |
Clear Evidence |
adenoma 0/48 0/48 1/48 1/48 3/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Mice |
MV |
Female |
Dosed-Water |
Lung
|
Clear Evidence |
Clear Evidence |
alveolar/bronchiolar adenoma 1/47 4/47 6/48 11/45 19/45
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Mice |
MV |
Male |
Dosed-Water |
Lung
|
Clear Evidence |
Clear Evidence |
alveolar/bronchiolar adenoma 5/47 6/46 13/47 10/45 19/48 alveolar/bronchiolar adenoma or carcinoma 6/47 6/46 14/47 10/45 20/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Mice |
MV |
Female |
Dosed-Water |
Mammary Gland
|
Clear Evidence |
Clear Evidence |
adenoacanthoma 0/47 1/46 1/48 2/45 4/42 adenocarcinoma 0/47 4/46 6/48 2/45 13/42 adenoacanthoma or adenocarcinoma 0/47 4/46 7/48 4/45 17/42
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Mammary Gland
|
Clear Evidence |
Clear Evidence |
fibroadenoma 16/48 18/48 24/46 22/47 31/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Oral Cavity
|
Clear Evidence |
Clear Evidence |
squamous cell papilloma or carcinoma 0/48 2/48 1/48 3/48 5/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Mice |
MV |
Female |
Dosed-Water |
Ovary
|
Clear Evidence |
Clear Evidence |
benign granulose cell tumor 0/46 1/45 0/48 1/45 5/42
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Pancreas Islet Cell
|
Clear Evidence |
Clear Evidence |
adenoma 1/46 2/48 4/48 1/48 6/48 carcinoma 0/46 0/48 0/48 1/48 0/48 adenoma or carcinoma 1/46 2/48 4/48 2/48 6/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Mice |
MV |
Female |
Dosed-Water |
Skin
|
Clear Evidence |
Clear Evidence |
fibrosarcoma, fibrous histocytoma, myxosarcoma, neurofibrosarcoma, or sarcoma 0/48 0/46 3/48 10/45 6/43 squamous cell carcinoma 0/48 0/46 0/48 0/45 2/43
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Skin
|
Clear Evidence |
Clear Evidence |
subcutaneous tissue fibroma, fibrosarcoma or sarcoma 1/48 0/48 0/48 1/48 5/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Testis
|
Clear Evidence |
Clear Evidence |
malignant mesothelioma 1/48 2/48 1/48 1/48 5/48
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Thyroid Gland Follicular Cell
|
Clear Evidence |
Clear Evidence |
adenoma 0/48 0/48 1/48 0/48 2/47 carcinoma 0/48 0/48 1/48 3/48 2/47 adenoma or carcinoma 0/48 0/48 2/48 3/48 4/47
|
Neoplastic Lesions
|
No
|
TR-575
|
79-06-1 |
Acrylamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Thyroid Gland Follicular Cell
|
Clear Evidence |
Clear Evidence |
adenoma 0/47 1/48 1/47 1/48 3/48 carcinoma 1/47 2/48 3/47 6/48 6/48 l adenoma or carcinoma 1/47 3/48 4/47 6/48 9/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
All Organs
|
Clear Evidence |
Equivocal Evidence |
Mononuclear Cell Leukemia 21/48 26/48 27/48 27/47 31/48
|
May Have Been Related
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
All Organs
|
Clear Evidence |
Clear Evidence |
Mononuclear Cell Leukemia 14/48 11/48 21/48 19/48 27/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Clitoral Gland
|
Clear Evidence |
Clear Evidence |
carcinoma 4/48 6/48 7/48 11/48 14/47
|
Neoplastic Lesions
|
Yes
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Epididymis
|
Clear Evidence |
Clear Evidence |
malignant mesothelioma 0/48 1/45 3/48 10/47 17/47
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Epididymis or Testis
|
Clear Evidence |
Clear Evidence |
malignant mesothelioma 0/48 1/48 3/48 10/47 17/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Female |
Dosed-Water |
Forestomach
|
Clear Evidence |
Clear Evidence |
squamous cell papilloma 1/45 1/45 1/47 5/45 9/44
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Male |
Dosed-Water |
Forestomach
|
Clear Evidence |
Clear Evidence |
squamous cell papilloma 0/47 2/45 3/48 2/45 10/41 squamous cell carcinoma 0/47 0/45 0/48 0/45 2/41 squamous cell papilloma or carcinoma 0/47 2/45 3/48 2/45 12/41
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Forestomach
|
Clear Evidence |
Clear Evidence |
squamous cell papilloma 0/48 1/48 0/48 0/47 3/46
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Female |
Dosed-Water |
Harderian Gland
|
Clear Evidence |
Clear Evidence |
adenoma 2/45 19/47 20/47 24/46 40/46
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Male |
Dosed-Water |
Harderian Gland
|
Clear Evidence |
Clear Evidence |
adenoma 3/47 17/47 23/47 32/46 42/47
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Heart
|
Clear Evidence |
Clear Evidence |
malignant schwannoma 2/48 3/48 3/48 7/47 8/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Female |
Dosed-Water |
Lung
|
Clear Evidence |
Clear Evidence |
alveolar/bronchiolar adenoma 3/46 5/48 3/47 7/47 9/44
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Male |
Dosed-Water |
Lung
|
Clear Evidence |
Clear Evidence |
alveolar/bronchiolar adenoma 0/47 7/46 7/47 13/47 17/47
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Female |
Dosed-Water |
Mammary Gland
|
Clear Evidence |
Clear Evidence |
adenoacanthoma 0/45 0/48 0/47 1/47 8/45 adenocarcinoma 1/45 1/48 2/47 9/47 11/45 adenoacanthoma or adenocarcinoma 1/45 1/48 2/47 9/47 18/45
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Mammary Gland
|
Clear Evidence |
Clear Evidence |
fibroadenoma 16/48 26/48 35/48 33/48 36/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Oral Cavity
|
Clear Evidence |
Clear Evidence |
Oral mucosa or tongue: squamous cell papilloma or carcinoma 1/48 2/48 2/48 2/48 7/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Oral Cavity
|
Clear Evidence |
Clear Evidence |
Oral mucosa: squamous cell papilloma 1/48 1/48 2/48 0/48 4/48 squamous cell carcinoma 0/48 0/48 0/48 1/48 2/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Oral Cavity
|
Clear Evidence |
Clear Evidence |
Tongue: squamous cell papilloma 0/48 1/48 0/48 1/48 0/48 squamous cell carcinoma 0/48 0/48 0/48 0/48 1/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Oral Cavity
|
Clear Evidence |
Clear Evidence |
Tongue: squamous cell papilloma 0/48 1/48 0/48 1/47 4/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Oral Cavity
|
Clear Evidence |
Clear Evidence |
Oral mucosa: squamous cell papilloma 1/48 1/48 0/48 2/47 3/48 squamous cell carcinoma 1/48 0/48 1/48 1/47 0/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Oral Cavity
|
Clear Evidence |
Clear Evidence |
Oral mucosa or tongue: squamous cell papilloma or carcinoma 2/48 2/48 2/48 3/47 7/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Female |
Dosed-Water |
Ovary
|
Clear Evidence |
Equivocal Evidence |
granulosa cell tumor – benign or malignant 0/45 0/47 0/47 3/46 3/44
|
May Have Been Related
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Female |
Dosed-Water |
Skin
|
Clear Evidence |
Clear Evidence |
fibrosarcoma 0/45 1/48 2/47 2/47 9/45 sarcoma 0/45 0/48 1/47 3/47 3/45 fibrosarcoma or sarcoma 0/45 1/48 3/47 5/47 12/45
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Mice |
MV |
Male |
Dosed-Water |
Skin
|
Clear Evidence |
Clear Evidence |
squamous cell papilloma 0/47 1/48 2/47 1/47 8/46 squamous cell carcinoma 0/47 0/48 0/47 0/47 2/46 squamous cell papilloma or carcinoma 0/47 1/48 2/47 1/47 9/46
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Testis
|
Clear Evidence |
Clear Evidence |
malignant mesothelioma 0/48 1/47 3/48 6/47 13/48
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Female |
Dosed-Water |
Thyroid Gland Follicular Cell
|
Clear Evidence |
Clear Evidence |
adenoma 0/48 3/48 3/46 1/46 5/47 follicular cell carcinoma 0/48 0/48 2/46 3/46 3/47 follicular cell adenoma or carcinoma 0/48 3/48 5/46 4/46 8/47
|
Neoplastic Lesions
|
No
|
TR-588
|
5694-00-8 |
Glycidamide |
Rats |
F344 (NCTR) |
Male |
Dosed-Water |
Thyroid Gland Follicular Cell
|
Clear Evidence |
Clear Evidence |
adenoma 2/47 1/42 3/48 3/47 8/46 follicular cell carcinoma 0/47 2/42 3/48 1/47 5/46 follicular cell adenoma or carcinoma 2/47 3/42 6/48 4/47 13/46
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Female |
Gavage |
Brain
|
Clear Evidence |
Clear Evidence |
GLIOMA 0/50 4/50 4/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Male |
Gavage |
Brain
|
Clear Evidence |
Clear Evidence |
GLIOMA 0/50 5/50 6/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Female |
Gavage |
Clitoral Gland
|
Clear Evidence |
Clear Evidence |
ADENOMA 3/50 7/50 7/50, ADENOCARCINOMA 0/50 1/50 0/50, OR CARCINOMA 2/50 1/50 5/50 COMBINED 5/50 9/50 12/50
|
Neoplastic Lesions
|
Yes
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Male |
Gavage |
Epididymis
|
Clear Evidence |
Equivocal Evidence |
SARCOMA 0/50 0/50 2/50
|
May Have Been Related
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Male |
Gavage |
Forestomach
|
Clear Evidence |
Clear Evidence |
SQUAMOUS CELL PAPILLOMA 0/50 2/50 9/50 OR SQUAMOUS CELL CARCINOMA 1/50 0/50 1/50 COMBINED 1/50 2/50 10/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Female |
Gavage |
Forestomach
|
Clear Evidence |
Clear Evidence |
SQUAMOUS CELL PAPILLOMA 0/50 4/50 8/50 OR SQUAMOUS CELL CARCINOMA 0/50 0/50 3/50 COMBINED 0/50 4/50 11/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Male |
Gavage |
Forestomach
|
Clear Evidence |
Clear Evidence |
SQUAMOUS CELL PAPILLOMA 0/50 1/50 5/50 OR SQUAMOUS CELL CARCINOMA 1/50 1/50 2/50 COMBINED 1/50 2/50 6/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Female |
Gavage |
Glandular Stomach
|
Clear Evidence |
Equivocal Evidence |
FIBROSARCOMA 0/50 0/50 2/50
|
May Have Been Related
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Female |
Gavage |
Harderian Gland
|
Clear Evidence |
Clear Evidence |
ADENOMA 4/50 10/50 16/50 OR ADENOCARCINOMA 0/50 1/50 1/50 COMBINED 4/50 11/50 17/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Male |
Gavage |
Harderian Gland
|
Clear Evidence |
Clear Evidence |
ADENOMA 7/50 10/50 16/50 OR ADENOCARCINOMA 1/50 2/50 7/50 COMBINED 8/50 12/50 22/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Female |
Gavage |
Hematopoietic System
|
Clear Evidence |
Clear Evidence |
LEUKEMIA 13/50 14/50 20/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Male |
Gavage |
Kidney Tubular Cell
|
Clear Evidence |
Clear Evidence |
ADENOMATOUS POLYP 0/50 0/50 1/50 OR ADENOCARCINOMA 0/50 1/50 3/50 COMBINED 0/50 1/50 4/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Male |
Gavage |
Liver
|
Clear Evidence |
Clear Evidence |
ADENOMA 18/50 16/50 30/50 OR CARCINOMA 10/50 17/50 8/50 COMBINED 24/50 31/50 35/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Male |
Gavage |
Lung
|
Clear Evidence |
Clear Evidence |
ALVEOLAR/BRONCHIOLAR ADENOMA 6/50 6/50 8/50 OR ALVEOLAR/BRONCHIOLAR CARCINOMA 7/50 5/50 14/50 COMBINED 13/50 11/50 21/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Female |
Gavage |
Mammary Gland
|
Clear Evidence |
Clear Evidence |
ADENOMA 0/50 1/50 0/50, FIBROADENOMA 1/50 0/50 0/50, OR ADENOCARCINOMA 1/50 5/50 15/50 COMBINED 2/50 6/50 15/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Female |
Gavage |
Mammary Gland
|
Clear Evidence |
Clear Evidence |
FIBROADENOMA 14/50 32/50 29/50; ADENOCARCINOMA 1/50 11/50 16/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Male |
Gavage |
Mammary Gland
|
Clear Evidence |
Clear Evidence |
FIBROADENOMA 3/50 8/50 7/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Male |
Gavage |
Mesothelium (Abdominal Cavity/Tunica Vaginalis)
|
Clear Evidence |
Clear Evidence |
MESOTHELIOMA 3/50 34/50 39/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Female |
Gavage |
Oral Cavity
|
Clear Evidence |
Clear Evidence |
SQUAMOUS CELL PAPILLOMA 1/50 3/50 6/50 OR SQUAMOUS CELL CARCINOMA 0/50 0/50 1/50 COMBINED 1/50 3/50 7/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Female |
Gavage |
Skin
|
Clear Evidence |
Clear Evidence |
SQUAMOUS CELL PAPILLOMA 0/50 0/50 1/50 OR SQUAMOUS CELL CARCINOMA 0/50 0/50 1/50 COMBINED 0/50 0/50 2/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Male |
Gavage |
Skin
|
Clear Evidence |
Clear Evidence |
SQUAMOUS CELL PAPILLOMA 0/50 0/50 4/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Male |
Gavage |
Skin
|
Clear Evidence |
Clear Evidence |
SEBACEOUS GLAND ADENOMA 0/50 0/50 1/50, BASAL CELL CARCINOMA 0/50 4/50 2/50, OR SEBACEOUS GLAND ADENOCARCINOMA 0/50 0/50 1/50 COMBINED 0/50 5/50 4/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Female |
Gavage |
Subcutaneous Tissue
|
Clear Evidence |
Clear Evidence |
SARCOMA 0/50 1/50 6/50 OR FIBROSARCOMA 0/50 2/50 3/50 COMBINED 0/50 3/50 9/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Female |
Gavage |
Thyroid Gland Follicular Cell
|
Clear Evidence |
Clear Evidence |
ADENOMA 0/50 1/50 0/49 OR CARCINOMA 0/50 0/50 3/49 COMBINED 0/50 1/50 3/49
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Male |
Gavage |
Thyroid Gland Follicular Cell
|
Clear Evidence |
Clear Evidence |
ADENOMA 0/50 2/50 2/50 OR CARCINOMA 1/50 2/50 5/50 COMBINED 1/50 4/50 6/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Male |
Gavage |
Urinary Bladder
|
Clear Evidence |
Equivocal Evidence |
CARCINOMA 0/50 1/50 1/50
|
May Have Been Related
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Mice |
B6C3F1 |
Female |
Gavage |
Uterus/Cervix
|
Clear Evidence |
Clear Evidence |
CARCINOMA 0/50 0/50 1/50 OR ADENOCARCINOMA 0/50 3/50 2/50 COMBINED 0/50 3/50 3/50
|
Neoplastic Lesions
|
No
|
TR-374
|
556-52-5 |
Glycidol |
Rats |
F344/N |
Male |
Gavage |
Zymbal Gland
|
Clear Evidence |
Clear Evidence |
CARCINOMA 1/50 3/50 6/50
|
Neoplastic Lesions
|