Search Results

One moment please while the data are loaded...

The DNTP Technical Report (TR) Level of Evidence Criteria are available here: https://ntp.niehs.nih.gov/go/baresults. In the table below this information is further delineated into three fields:

Level of Evidence: The overall category of evidence of carcinogenic activity for the TR, Species, Strain and Sex
Organ Site Call: The level of evidence supported by the specific organ site for the TR, Species, Strain and Sex. When the Organ Site Call directly supports the TR Level Of Evidence the Finding Type flag is set to “Neoplastic Lesion”. Some Organ Site Calls could support a separate call of Equivocal Evidence; this is noted in Finding Type by the flag “May Have Been Related”
Finding Type: Further identification of the Organ Site Call. Where this says “Neoplastic Lesion” the Organ Site Call supports the TR Level of Evidence and the Organ Site Call is the same as that of the TR. Where Finding Type says “May Have Been Related” the TR Level of Evidence for other responses led to an overall call of Clear or Some Evidence but the specified organ supports a call of Equivocal Evidence.

Displays results that match exactly with the given criteria.
Exact Match	Publication No.	CASRN	Test Article Name	Species	Strain	Sex	Route	Organ	Level of Evidence	Organ Site Call	Tumor Type/Incidence	Finding Type
Yes	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Male	Dosed-Feed	Ureter	Positive	Positive	(TRANSITIONAL CELL CARCINOMA)	Neoplastic Lesions
Yes	TR-006	139-13-9	Nitrilotriacetic acid (NTA)	Rats	F344/N	Male	Dosed-Feed	Ureter	Positive	Positive	(ADENOMA OR PAPILLOMA)	Neoplastic Lesions
Yes	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Female	Dosed-Feed	Ureter	Positive	Positive	(TRANSITIONAL CELL CARCINOMA)	Neoplastic Lesions
Yes	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Ureter	Clear Evidence	Equivocal Evidence	Transitional epithelial carcinoma: 0/0 0/1 0/0 1/2	May Have Been Related
Yes	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Male	Gavage	Ureter	Clear Evidence	Equivocal Evidence	Transitional epithelial carcinoma: 0/43 0/45 1/47 0/50	May Have Been Related

Displays all results in TRs which have data that match the given criteria.
Exact Match	Publication No.	CASRN	Test Article Name	Species	Strain	Sex	Route	Organ	Level of Evidence	Organ Site Call	Tumor Type/Incidence	Finding Type
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Adrenal Gland Cortex	Clear Evidence	Equivocal Evidence	Adenoma 1/50 1/50 3/50 4/49	May Have Been Related
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	All Organs	Clear Evidence	Equivocal Evidence	Malignant Lymphoma: 2/50 5/50 8/50 7/50	May Have Been Related
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Forestomach	Clear Evidence	Clear Evidence	Squamous cell carcinoma 0/50 1/50 1/50 4/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Male	Gavage	Forestomach	Clear Evidence	Clear Evidence	Squamous cell carcinoma 0/50 1/50 1/49 3/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Forestomach	Clear Evidence	Clear Evidence	Squamous cell papilloma or carcinoma 0/50 1/50 0/50 4/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Liver	Clear Evidence	Clear Evidence	Cholangiocarcinoma 1/50 1/50 1/49 3/49	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Liver	Clear Evidence	Clear Evidence	Cholangiocarcinoma 0/50 4/50 4/50 6/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Lung	Clear Evidence	Clear Evidence	Alveolar/bronchiolar adenoma or carcinoma 0/49 2/50 1/50 4/50 alveolar/bronchiolar adenoma or carcinoma 3/49 8/50 5/50 10/50 cystic keratinizing epithelioma 0/49 0/50 0/50 2/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Male	Gavage	Lung	Clear Evidence	Clear Evidence	Alveolar/bronchiolar adenoma 5/50 16/50 12/49 6/50 alveolar/bronchiolar adenoma or carcinoma 7/50 17/50 15/49 6/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Lung	Clear Evidence	Clear Evidence	Cystic keratinizing epithelioma 0/50 6/50 26/49 39/49	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Lung	Clear Evidence	Clear Evidence	Cystic keratinizing epithelioma 0/50 14/50 31/50 37/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Female	Gavage	Oral Cavity	Clear Evidence	Clear Evidence	Mucosa: Gingival squamous cell carcinoma 0/50 0/50 4/50 6/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Oral Cavity	Clear Evidence	Clear Evidence	Mucosa: Gingival squamous cell carcinoma 1/50 5/50 4/50 5/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Skin	Clear Evidence	Clear Evidence	Fibrosarcoma 1/50 6/50 5/50 8/50 fibrosarcoma or malignant schwannoma 2/50 8/50 7/50 12/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Thoracic Cavity	Clear Evidence	Equivocal Evidence	Malignant Schwannoma: 0/50 0/50 1/50 3/50	May Have Been Related
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Rats	Harlan Sprague-Dawley	Male	Gavage	Thyroid Gland Follicular Cell	Clear Evidence	Clear Evidence	adenoma 0/50 3/50 4/50 4/50	Neoplastic Lesions
Yes	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Ureter	Clear Evidence	Equivocal Evidence	Transitional epithelial carcinoma: 0/0 0/1 0/0 1/2	May Have Been Related
Yes	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Male	Gavage	Ureter	Clear Evidence	Equivocal Evidence	Transitional epithelial carcinoma: 0/43 0/45 1/47 0/50	May Have Been Related
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Female	Gavage	Urinary System	Clear Evidence	Clear Evidence	Urethra: Transitional epithelial gland carcinoma 0/50 0/50 0/50 2/50	Neoplastic Lesions
No	TR-558	14047-09-7	3,3',4,4'-Tetrachloroazobenzene	Mice	B6C3F1/N	Male	Gavage	Urinary System	Clear Evidence	Clear Evidence	Urethra: Transitional epithelial gland carcinoma 0/50 32/50 46/49 49/50	Neoplastic Lesions
No	TR-006	139-13-9	Nitrilotriacetic acid (NTA)	Mice	B6C3F1	Female	Dosed-Feed	Kidney Tubular Cell	Positive	Positive	ADENOCARCINOMA	Neoplastic Lesions
No	TR-006	139-13-9	Nitrilotriacetic acid (NTA)	Mice	B6C3F1	Male	Dosed-Feed	Kidney Tubular Cell	Positive	Positive	ADENOCARCINOMA	Neoplastic Lesions
No	TR-006	139-13-9	Nitrilotriacetic acid (NTA)	Rats	F344/N	Male	Dosed-Feed	Kidney Tubular Cell	Positive	Positive	ADENOMA OR ADENOCARCINOMA	Neoplastic Lesions
Yes	TR-006	139-13-9	Nitrilotriacetic acid (NTA)	Rats	F344/N	Male	Dosed-Feed	Ureter	Positive	Positive	(ADENOMA OR PAPILLOMA)	Neoplastic Lesions
No	TR-006	139-13-9	Nitrilotriacetic acid (NTA)	Rats	F344/N	Female	Dosed-Feed	Urinary Bladder	Positive	Positive	(TRANSITIONAL CELL CARCINOMA)	Neoplastic Lesions
No	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Mice	B6C3F1	Female	Dosed-Feed	Unspecified	Negative		Not applicable	Not applicable
No	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Mice	B6C3F1	Male	Dosed-Feed	Unspecified	Negative		Not applicable	Not applicable
No	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Male	Dosed-Feed	Kidney Transitional Cell	Equivocal Evidence	Equivocal	PAPILLOMA	Neoplastic Lesions
No	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Male	Dosed-Feed	Kidney Transitional Cell	Positive	Positive	CARCINOMA	Neoplastic Lesions
No	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Male	Dosed-Feed	Kidney Tubular Cell	Equivocal Evidence	Equivocal	ADENOCARCINOMA	Neoplastic Lesions
No	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Female	Dosed-Feed	Kidney Tubular Cell	Positive	Positive	ADENOMA OR ADENOCARCINOMA	Neoplastic Lesions
No	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Male	Dosed-Feed	Kidney Tubular Cell	Positive	Positive	ADENOCARCINOMA OR CARCINOMA	Neoplastic Lesions
Yes	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Female	Dosed-Feed	Ureter	Positive	Positive	(TRANSITIONAL CELL CARCINOMA)	Neoplastic Lesions
Yes	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Male	Dosed-Feed	Ureter	Positive	Positive	(TRANSITIONAL CELL CARCINOMA)	Neoplastic Lesions
No	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Female	Dosed-Feed	Urinary Bladder	Equivocal Evidence	Equivocal	(TRANSITIONAL CELL CARCINOMA)	Neoplastic Lesions
No	TR-006	18662-53-8	Nitrilotriacetic acid trisodium monohydrate	Rats	F344/N	Female	Dosed-Feed	Urinary Bladder	Positive	Positive	(TRANSITIONAL CELL CARCINOMA)	Neoplastic Lesions