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Publications

Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells. Buick JK, Moffat I, Williams A, Swartz CD, Recio L, Hyduke DR, Li HH, Fornace AJ Jr, Aubrecht J, Yauk CL. Environ Mol Mutagen. 2015 Jul;56(6):520-34. doi: 10.1002/em.21940. PMCID: PMC4506226
Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells. Li HH, Hyduke DR, Chen R, Heard P, Yauk CL, Aubrecht J, Fornace AJ Jr. Environ Mol Mutagen. 2015 Jul;56(6):505-19. doi: 10.1002/em.21941. PMID: 25733355
A predictive toxicogenomics signature to classify genotoxic versus non-genotoxic chemicals in human TK6 cells. Williams A, Buick JK, Moffat I, Swartz CD, Recio L, Hyduke DR, Li HH, Fornace AJ Jr, Aubrecht J, Yauk CL. Data Brief. 2015 Aug 24;5:77-83. doi: 10.1016/j.dib.2015.08.013. PMCID: PMC4564388
Application of the TGx-DDI transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9. Yauk CL, Buick JK, Williams A, Swartz CD, Recio L, Li HH, Fornace AJ Jr, Thomson EM, Aubrecht J. Environ Mol Mutagen. 2016 Mar 4. doi: 10.1002/em.22004. PMID: 26946220
Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water. Moffat I, Chepelev NL, Labib S, Bourdon-Lacombe J, Kuo B, Buick JK, Lemieux F, Williams A, Halappanavar S, Malik AI, Luijten M, Aubrecht J, Hyduke DR, Fornace AJ Jr, Swartz CD, Recio L, Yauk CL. J. Crit Rev Toxicol 2015 Jan; 45(1):1-43. doi: 10.3109/10408444.2014.973934. Review. PMID: PMC4521608
The TGx-28.65 Biomarker Online Application for Analysis of Transcriptomics Data to Identify DNA Damage-inducing Chemicals in Human Cell Cultures. Jackson MA, Yang L, Lea IA, Rashid A, Kuo B, Williams A, Yauk CL, Fostel J. Environ Mol Mutagen. 2017 Aug;58(7):529-535. doi: 10.1002/em.22114. PMID: 28766826