TOX-91: Toxicity Report Tables & Curves

Pathology Tables, Survival and Growth Curves from NTP
Short-Term Studies

TOX-91: Abrasive Blasting Agents (Blasting Sand,Coal Slag, Crushed Glass, Garnet, Specular Hematite)

Short-Term

2-Week Blasting Sand Study Tables - Rats

• E03 - Growth Curves (175 KB)
• E04 - Mean Body Weights and Survival Table (12 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (18 KB)
• P04 - Neoplasms by Individual Animal (59 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (59 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (20 KB)
• P14 - Individual Animal Pathology Data (50 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 KB)
• P40 - Survival Curves (196 KB)

2-Week Blasting Sand Individual Animal Data - Rats

• Male Individual Animal Body Weight Data (6 KB)
• Male Individual Animal Non Neoplastic Pathology Data (7 KB)
• Male Individual Animal Survival Data (5 KB)
• Male Individual Animal Terminal Body Weight Data (8 KB)

2-Week Coal Slag Study Tables - Rats

• E03 - Growth Curves (167 KB)
• E04 - Mean Body Weights and Survival Table (14 KB)
• E05 - Clinical Observations Summary (12 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (18 KB)
• P04 - Neoplasms by Individual Animal (59 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (59 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (27 KB)
• P14 - Individual Animal Pathology Data (50 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 KB)
• P40 - Survival Curves (187 KB)

2-Week Coal Slag Individual Animal Data - Rats

• Male Individual Animal Body Weight Data (6 KB)
• Male Individual Animal Non Neoplastic Pathology Data (8 KB)
• Male Individual Animal Survival Data (5 KB)
• Male Individual Animal Terminal Body Weight Data (8 KB)
• Male Individual Clinical Observations (2 KB)

2-Week Crushed Glass Study Tables - Rats

• E03 - Growth Curves (155 KB)
• E04 - Mean Body Weights and Survival Table (13 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (20 KB)
• P04 - Neoplasms by Individual Animal (57 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (57 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (25 KB)
• P14 - Individual Animal Pathology Data (51 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 KB)
• P40 - Survival Curves (188 KB)

2-Week Crushed Glass Individual Animal Data - Rats

• Male Individual Animal Body Weight Data (6 KB)
• Male Individual Animal Non Neoplastic Pathology Data (17 KB)
• Male Individual Animal Survival Data (5 KB)
• Male Individual Animal Terminal Body Weight Data (8 KB)

2-Week Garnet Study Tables - Rats

• E03 - Growth Curves (165 KB)
• E04 - Mean Body Weights and Survival Table (12 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (16 KB)
• P04 - Neoplasms by Individual Animal (57 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (58 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (20 KB)
• P14 - Individual Animal Pathology Data (49 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (17 KB)
• P40 - Survival Curves (181 KB)

2-Week Garnet Individual Animal Data - Rats

• Male Individual Animal Body Weight Data (6 KB)
• Male Individual Animal Non Neoplastic Pathology Data (11 KB)
• Male Individual Animal Survival Data (5 KB)
• Male Individual Animal Terminal Body Weight Data (8 KB)

2-Week Specular Hematite Study Tables - Rats

• E03 - Growth Curves (171 KB)
• E04 - Mean Body Weights and Survival Table (13 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (18 KB)
• P04 - Neoplasms by Individual Animal (68 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (70 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (23 KB)
• P14 - Individual Animal Pathology Data (62 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 KB)
• P40 - Survival Curves (190 KB)

2-Week Specular Hematite Individual Animal Data - Rats

• Male Individual Animal Body Weight Data (8 KB)
• Male Individual Animal Non Neoplastic Pathology Data (14 KB)
• Male Individual Animal Survival Data (6 KB)
• Male Individual Animal Terminal Body Weight Data (9 KB)

Interim of 39-Week Blasting Sand Study at 4-Weeks - Rats

• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (18 KB)
• P04 - Neoplasms by Individual Animal (60 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (69 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (30 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 KB)

Interim of 39-Week Blasting Sand Study at 16-Weeks - Rats

• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (19 KB)
• P04 - Neoplasms by Individual Animal (64 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (73 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (50 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 KB)

Interim of 39-Week Blasting Sand Study at 26-Weeks - Rats

• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (19 KB)
• P04 - Neoplasms by Individual Animal (61 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (76 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (60 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 KB)

39-Week Blasting Sand Study Tables - Rats

• E03 - Growth Curves (212 KB)
• E04 - Mean Body Weights and Survival Table (14 KB)
• E05 - Clinical Observations Summary (12 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (19 KB)
• P04 - Neoplasms by Individual Animal (65 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (21 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (78 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (70 KB)
• P14 - Individual Animal Pathology Data (288 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (20 KB)
• P40 - Survival Curves (208 KB)

39-Week Blasting Sand Individual Animal Data - Rats

• Male Individual Animal Body Weight Data (118 KB)
• Male Individual Animal Clinical Observations (4 KB)
• Male Individual Animal Neoplastic Pathology Data (3 KB)
• Male Individual Animal Non Neoplastic Pathology Data (296 KB)
• Male Individual Animal Organ Weight Data (69 KB)
• Male Individual Animal Survival Data (25 KB)

Interim of 39-Week Specular Hematite Study at 4-Weeks - Rats

• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (18 KB)
• P04 - Neoplasms by Individual Animal (57 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (62 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (39 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 KB)

Interim of 39-Week Specular Hematite Study at 16-Weeks - Rats

• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (19 KB)
• P04 - Neoplasms by Individual Animal (57 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (74 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (63 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 KB)

Interim of 39-Week Specular Hematite Study at 26-Weeks - Rats

• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (19 KB)
• P04 - Neoplasms by Individual Animal (58 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (19 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (77 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (88 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (20 KB)

39-Week Specular Hematite Study Tables - Rats

• E03 - Growth Curves (212 KB)
• E04 - Mean Body Weights and Survival Table (14 KB)
• E05 - Clinical Observations Summary (12 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (19 KB)
• P04 - Neoplasms by Individual Animal (60 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (21 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (78 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (85 KB)
• P14 - Individual Animal Pathology Data (289 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (20 KB)
• P40 - Survival Curves (201 KB)

39-Week Specular Hematite Individual Animal Data - Rats

• Male Individual Animal Body Weight Data (118 KB)
• Male Individual Animal Clinical Observations (4 KB)
• Male Individual Animal Neoplastic Pathology Data (3 KB)
• Male Individual Animal Non Neoplastic Pathology Data (296 KB)
• Male Individual Animal Organ Weight Data (69 KB)
• Male Individual Animal Survival Data (25 KB)