TR-597: Technical Report Pathology Tables and Curves
Pathology Tables, Survival and Growth Curves from NTP
Long-Term, Genetic Toxicology Studies
DOI:
https://doi.org/10.22427/NTP-DATA-TR-597
The 2-year rat pathology tables generated July 11, 2017 have been replaced on the NTP website due to a correction in number of animals examined in the control and high exposure group.
Tables updated to include litter-based statistical tests
The 2-year rat pathology tables generated on September 22,2017 were updated due to animal 151 having a neoplasm (malignant meningioma) in the Trigeminal Nerve that was recorded as a primary lesion instead of as a metastatic lesion. The primary lesion was in the brain.
The P08 with Rao-Scott was replaced on 1/13/2020 based on a decision not to combine brain and spinal cord for analysis.
The 2-year rat pathology tables generated July 11, 2017 have been replaced on the NTP website due to a correction in number of animals examined in the control and high exposure group.
Tables updated to include litter-based statistical tests
The 2-year rat pathology tables generated on September 22,2017 were updated due to animal 151 having a neoplasm (malignant meningioma) in the Trigeminal Nerve that was recorded as a primary lesion instead of as a metastatic lesion. The primary lesion was in the brain.
The P08 with Rao-Scott was replaced on 1/13/2020 based on a decision not to combine brain and spinal cord for analysis.
TR-597: 2-Hydroxy-4-methoxybenzophenone
Long-Term
Interim of Chronic with Perinatal Study at 3 Months - Rats
- E03 - Growth Curves (412 KB)
- E04 - Mean Body Weights and Survival Table (15 KB)
- E05 - Clinical Observations Summary (24 KB)
- E08 - Feed Water and Compound Consumption Table (42 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (28 KB)
- P04 - Neoplasms by Individual Animal (113 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (32 KB)
- P08 - Statistical Analysis of Primary Tumors (11 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (115 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (65 KB)
- P11 - Statistical Analysis of Survival Data (22 KB)
- P14 - Individual Animal Pathology Data (109 KB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (114 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (28 KB)
- P40 - Survival Curves (410 KB)
- PA06 - Organ Weights Summary (89 KB)
- R02 - Reproductive Performance Summary (39 KB)
Chronic with Perinatal Study Tables - Rats
- E03 - Growth Curves (64 KB)
- E04 - Mean Body Weights and Survival Table (18 KB)
- E05 - Clinical Observations Summary (24 KB)
- E08 - Feed Water and Compound Consumption Table (37 KB)
- HMB Chronic Perinatal: Summary Pup Body Weights (20 KB)
- HMB Chronic Perinatal Female Harlan Sprague Dawley Rats: Gestational and Lactational Food Consumption (g/animal/day) (21 KB)
- HMB Chronic Perinatal Female Harlan Sprague Dawley Rats: Gestational Body and Body Weight Gains (19 KB)
- HMB Chronic Perinatal Female Harlan Sprague Dawley Rats: Lactational Body and Body Weight Gains (19 KB)
- HMB Chronic Perinatal Female Harlan Sprague Dawley Rats Gestational and Lactational Chemical Consumption (mg HMB/kg body weight/day) (19 KB)
- HMB Chronic Perinatal Litter Data Analysis in Female Harlan Sprague Dawley Rats: Live Litter Size (20 KB)
- HMB Chronic Perinatal Litter Data Analysis in Female Harlan Sprague Dawley Rats: PND1 Data (21 KB)
- HMB Chronic Perinatal Litter Data Analysis in Female Harlan Sprague Dawley Rats: Survival (18 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (51 KB)
- P04 - Neoplasms by Individual Animal (604 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (45 KB)
- P08 - Statistical Analysis of Primary Tumors with Rao-Scott (207 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (736 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (324 KB)
- P11 - Statistical Analysis of Survival Data (21 KB)
- P14 - Individual Animal Pathology Data (1 MB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (573 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (54 KB)
- P40 - Survival Curves (446 KB)
Chronic Individual Animal Data - Rats
- Female Individual Animal Body Weight All Animals (410 KB)
- Female Individual Animal Neoplastic Pathology Data (125 KB)
- Female Individual Animal Non Neoplastic Pathology Data (637 KB)
- Female Individual Animal Survival Data (36 KB)
- Female Individual Animal Terminal Body Weight Data (61 KB)
- Female Individual Clinical Observations (245 KB)
- Individual Animal DamID and PupID Data (18 KB)
- Individual Animal Organ Weight Data (8 KB)
- Individual Animal Reproductive Performance Data (10 KB)
- Male Individual Animal Body Weight All Animals (363 KB)
- Male Individual Animal Neoplastic Pathology Data (90 KB)
- Male Individual Animal Non Neoplastic Pathology Data (688 KB)
- Male Individual Animal Survival Data (36 KB)
- Male Individual Animal Terminal Body Weight Data (61 KB)
- Male Individual Clinical Observations (156 KB)
Chronic Study Tables - Mice
- E03 - Growth Curves (66 KB)
- E04 - Mean Body Weights and Survival Table (24 KB)
- E05 - Clinical Observations Summary (19 KB)
- E08 - Feed Water and Compound Consumption Table (31 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (58 KB)
- P04 - Neoplasms by Individual Animal (646 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (47 KB)
- P08 - Statistical Analysis of Primary Tumors (141 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (807 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (503 KB)
- P11 - Statistical Analysis of Survival Data (23 KB)
- P14 - Individual Animal Pathology Data (1 MB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (578 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (59 KB)
- P40 - Survival Curves (59 KB)
Chronic Individual Animal Data - Mice
- Female Individual Animal Body Weight All Animals (303 KB)
- Female Individual Animal Neoplastic Pathology Data (100 KB)
- Female Individual Animal Non Neoplastic Pathology Data (760 KB)
- Female Individual Animal Survival Data (33 KB)
- Female Individual Animal Terminal Body Weight Data (56 KB)
- Female Individual Clinical Observations (20 KB)
- Male Individual Animal Body Weight All Animals (303 KB)
- Male Individual Animal Neoplastic Pathology Data (94 KB)
- Male Individual Animal Non Neoplastic Pathology Data (729 KB)
- Male Individual Animal Survival Data (33 KB)
- Male Individual Animal Terminal Body Weight Data (56 KB)
- Male Individual Clinical Observations (27 KB)
Genetic Toxicology
Genetic Toxicity Evaluation of 2-Hydroxy-4-methoxybenzophenone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 613844
- 613844 G06 - Ames Summary Data (137 KB)
Genetic Toxicity Evaluation of 2-Hydroxy-4-methoxybenzophenone (131-57-7) in Micronucleus Study A48127 in B6C3F1 Mice
- A48127 G04 - In Vivo Micronucleus Summary Data (71 KB)
- A48127 Individual Animal In Vivo Micronucleus Data.xlsx (13 KB)
Genetic Toxicity Evaluation of 2-Hydroxy-4-methoxybenzophenone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 381877
- 381877 G06 - Ames Summary Data (168 KB)
Genetic Toxicity Evaluation of 2-hydroxy-4-methoxybenzophenone (131-57-7) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G10260
- G10260 G06 - Ames Summary Data (78 KB)