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TR-602: Technical Report Pathology Tables and Curves

Pathology Tables, Survival and Growth Curves from NTP
Short-Term, Long Term, Genetic Toxicology, Other Information Studies


https://doi.org/10.22427/NTP-DATA-TR-602

NCBI SRA

The 3-month Rat P10 was updated on May 5, 2021 to remove the 20,000 ppm group since those animals were only on study for a few days.

The PA48 tables were updated on August 31, 2021 to reflect a change in endpoint names

The Food and Chemical Consumption tables for the Chronic Rats study were updated on November 29, 2021 to account for an animal removal in treatment group 2000 ppm

Following files were updated on Mar 3,2022:
2 year rat study: Gestational and Lactational Body Weights, PND 4-28 Litter Size and Survival
3-month Rat Study: All Litter data tables
3-month Mouse Study: R06 Andrology Summary

TCPP is produced as an isomeric mixture of four isomers. All NTP studies of TCPP have utilized a procured isomeric mixture and details are provided in the associated Technical Report. The data tables herein reference TCPP with CASRN 13674-84-5, which represents the major isomer of the TCPP mixture.

TR-602: Tris(Chloropropyl)phosphate


Short-Term


3-Month with Perinatal Study Tables - Rats

3-Month with Perinatal Individual Animal Data - Rats

3-Month Study Tables - Mice

3-Month Individual Animal Data - Mice


Long Term


Chronic with Perinatal Study Tables - Rats

Chronic with Perinatal Individual Animal Data - Rats

Chronic Study Tables - Mice

Individual Animal Data - Mice


Genetic Toxicology


Genetic Toxicity Evaluation of tris(Chloropropyl)phosphate (13674-84-5) in Micronucleus Study G20263 in Harlan Sprague-Dawley Rats

Genetic Toxicity Evaluation of tris(Chloropropyl)phosphate (13674-84-5) in Micronucleus Study G20263B in B6C3F1 Mice

Genetic Toxicity Evaluation of tris(Chloropropyl)phosphate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G20263C

Genetic Toxicity Evaluation of tris(Chloropropyl)phosphate in Salmonella Study 815918


Other Information


Toxicogenomics and Multiomics