Trim® VX (TRIMVX)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID8031578
Publications
TR-591
Toxicology and Carcinogenesis Studies of Trim® VX (CASRN TRIMVX) in Wistar Han Rats and B6C3F1 Mice (Inhalation Studies)
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C20523) of Metal Working Fluids: Trim® VX (TRIMVX) in Wistar Han Rats via Whole Body Respiratory Exposure
Study Tables
- E03 - Growth Curves (468 kB)
- E04 - Mean Body Weights and Survival Table (18 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (36 kB)
- P04 - Neoplasms by Individual Animal (213 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (258 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (258 kB)
- P14 - Individual Animal Pathology Data (290 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (37 kB)
- P40 - Survival Curves (452 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (37 kB)
- Female Individual Animal Non Neoplastic Pathology Data (159 kB)
- Female Individual Animal Organ Weight Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (37 kB)
- Male Individual Animal Clinical Observations (4 kB)
- Male Individual Animal Non Neoplastic Pathology Data (164 kB)
- Male Individual Animal Organ Weight Data (19 kB)
- Male Individual Animal Survival Data (11 kB)
3-Month Evaluation of the Toxicity (C20523) of Metal Working Fluids: Trim® VX (TRIMVX) in B6C3F1 Mice via Whole Body Respiratory Exposure
Study Tables
- E03 - Growth Curves (452 kB)
- E04 - Mean Body Weights and Survival Table (18 kB)
- E05 - Clinical Observations Summary (12 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 kB)
- P04 - Neoplasms by Individual Animal (214 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (248 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (103 kB)
- P14 - Individual Animal Pathology Data (292 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35 kB)
- P40 - Survival Curves (444 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (36 kB)
- Female Individual Animal Non Neoplastic Pathology Data (123 kB)
- Female Individual Animal Organ Weight Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (36 kB)
- Male Individual Animal Non Neoplastic Pathology Data (120 kB)
- Male Individual Animal Organ Weight Data (19 kB)
- Male Individual Animal Survival Data (11 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20523) of Metal Working Fluids: Trim® VX (TRIMVX) in Wistar Han Rats via Whole Body Respiratory Exposure
Study Tables
- E03 - Growth Curves (69 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (21 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (55 kB)
- P04 - Neoplasms by Individual Animal (686 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (49 kB)
- P08 - Statistical Analysis of Primary Tumors (215 kB)
- P08 - Statistical Analysis of Primary Tumors - Ovary and Uterus Pools (20 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (820 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (404 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (56 kB)
- P40 - Survival Curves (65 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (388 kB)
- Female Individual Animal Clinical Observations (119 kB)
- Female Individual Animal Neoplastic Pathology Data (117 kB)
- Female Individual Animal Non Neoplastic Pathology Data (1 mB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (394 kB)
- Male Individual Animal Clinical Observations (111 kB)
- Male Individual Animal Neoplastic Pathology Data (76 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20523) of Metal Working Fluids: Trim® VX (TRIMVX) in B6C3F1 Mice via Whole Body Respiratory Exposure
Study Tables
- E03 - Growth Curves (434 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (20 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (58 kB)
- P04 - Neoplasms by Individual Animal (828 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (54 kB)
- P08 - Statistical Analysis of Primary Tumors (205 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (616 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (74 kB)
- P40 - Survival Curves (436 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (382 kB)
- Female Individual Animal Clinical Observations (52 kB)
- Female Individual Animal Neoplastic Pathology Data (329 kB)
- Female Individual Animal Non Neoplastic Pathology Data (1 mB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (340 kB)
- Male Individual Animal Clinical Observations (73 kB)
- Male Individual Animal Neoplastic Pathology Data (163 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Metal Working Fluids: Trim® VX (TRIMVX) in Micronucleus Study G04093 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Metal Working Fluids: Trim® VX (TRIMVX) in Micronucleus Study G04093B in Wistar Han Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Metal Working Fluids: Trim® VX in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A94339
Summary Data
- G06 - Ames Summary Data (70 KB)