ADME/TK Evaluation (S0135) of p-Chloroaniline (106-47-8) in F344 Rats Exposed via Gavage Administration or Intravenous Injection
Radiolabel Description:
Carbon-14; [14C]p-Chloroaniline
Vehicles:
Intravenous, 100% ethanol:propylene glycol:water (1:1:8); Oral, dilute Hydrochloric acid (0.01 N).
Summary Data - Male Rats
- Gavage Single Dose (0.3 mg/kg, Excreta Study Duration 7 days) (66 KB)
- Gavage Single Dose (0.3 mg/kg, Study Duration 7 days) (70 KB)
- Gavage Single Dose (3.0 mg/kg, Excreta Study Duration 7 days) (54 KB)
- Gavage Single Dose (3.0 mg/kg, Study Duration 7 days) (70 KB)
- Gavage Single Dose (30 mg/kg, Excreta Study Duration 7 days) (54 KB)
- Gavage Single Dose (30 mg/kg, Study Duration 7 days) (84 KB)
- IV Single Dose (3 mg/kg, Bile Study Duration 3.5 hours) (43 KB)
- IV Single Dose (3.0 mg/kg, Tissue Concentration Study Duration 3 days) (84 KB)
- IV Single Dose (3.0 mg/kg, Tissue Percent Dose Study Duration 3 days) (84 KB)
- IV Toxicokinetics for Male Rats (2 MB)