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tris(2,3-Dibromopropyl) phosphate (126-72-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5021413


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Positive, Male, Rats
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  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Positive, Male, Mice
View
  • Positive, Female, Mice

Citation Information


NTP. tris(2,3-Dibromopropyl) phosphate (126-72-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-076 Bioassay of Tris (2,3-Dibromopropyl) Phosphate for Possible Carcinogenicity (CASRN 126-72-7)
Klose J, Pahl M, Bartmann K, Bendt F, Blum J, Dolde X, Förster N, Holzer AK, Hübenthal U, Keßel HE, Koch K, Masjosthusmann S, Schneider S, Stürzl LC, Woeste S, Rossi A, Covaci A, Behl M, Leist M, Tigges J, Fritsche E. Neurodevelopmental toxicity assessment of flame retardants using a human DNT in vitro testing battery. Cell Biol Toxicol. 2022 Oct;38(5):781-807. doi: 10.1007/s10565-021-09603-2. Epub 2021 May 10. PMID: 33969458

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of tris(2,3-Dibromopropyl) Phosphate (126-72-7) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of tris(2,3-Dibromopropyl) Phosphate (126-72-7) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of tris(2,3-Dibromopropyl) Phosphate (126-72-7) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of tris(2,3-Dibromopropyl) Phosphate (126-72-7) in Female B6C3F1 Mice Exposed via Dosed Feed

Other NTP Studies


ADME/TK Evaluation (S0036) of tris(2,3-Dibromopropyl) phosphate (126-72-7) in Sprague-Dawley Rats Exposed via Intravenous Injection