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tris(2,3-Dibromopropyl) phosphate (126-72-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5021413

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Positive, Male, Rats
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  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Citation Information

NTP. tris(2,3-Dibromopropyl) phosphate (126-72-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-076 Bioassay of Tris (2,3-Dibromopropyl) Phosphate for Possible Carcinogenicity (CASRN 126-72-7)
Klose J, Pahl M, Bartmann K, Bendt F, Blum J, Dolde X, Förster N, Holzer AK, Hübenthal U, Keßel HE, Koch K, Masjosthusmann S, Schneider S, Stürzl LC, Woeste S, Rossi A, Covaci A, Behl M, Leist M, Tigges J, Fritsche E. Neurodevelopmental toxicity assessment of flame retardants using a human DNT in vitro testing battery. Cell Biol Toxicol. 2022 Oct;38(5):781-807. doi: 10.1007/s10565-021-09603-2. Epub 2021 May 10. PMID: 33969458

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of tris(2,3-Dibromopropyl) Phosphate (126-72-7) in Male F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of tris(2,3-Dibromopropyl) Phosphate (126-72-7) in Female F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of tris(2,3-Dibromopropyl) Phosphate (126-72-7) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of tris(2,3-Dibromopropyl) Phosphate (126-72-7) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data

Other NTP Studies

ADME/TK Evaluation (S0036) of tris(2,3-Dibromopropyl) phosphate (126-72-7) in Sprague-Dawley Rats Exposed via Intravenous Injection
Data Summary

NTP Data Collections