U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

2,4,7-Trinitro-fluoren-9-one (129-79-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1026245

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2,4,7-Trinitro-fluoren-9-one (129-79-3).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2,4,7-Trinitro-fluoren-9-one (129-79-3).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. 2,4,7-Trinitro-fluoren-9-one (129-79-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TOX-13 Toxicity Studies of Trinitrofluorenone (CASRN 129-79-3) Administered by Topical Application and Dosed Feed to F344/N Rats and B6C3F1Mice
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C61961B) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in F344 Rats Exposed via Dosed Feed. NTP Special Study
Pathology Tables
Individual Animal Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C61961B) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C61961B) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C61961B) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in Micronucleus Study A44104 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2,4,7-Trinitro-fluoren-9-one in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 300390
Summary Data

Other NTP Studies

ADME/TK Evaluation (S0231) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in F344 Rats Exposed via Gavage, Intravenous Injection, Dermal or, Intraintestinal Administration
Data Summary

NTP Data Collections