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2,4,7-Trinitro-fluoren-9-one (129-79-3)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2,4,7-Trinitro-fluoren-9-one (129-79-3).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2,4,7-Trinitro-fluoren-9-one (129-79-3).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. 2,4,7-Trinitro-fluoren-9-one (129-79-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-13 Toxicity Studies of Trinitrofluorenone (CASRN 129-79-3) Administered by Topical Application and Dosed Feed to F344/N Rats and B6C3F1Mice
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C61961B) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in F344 Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C61961B) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C61961B) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C61961B) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in Micronucleus Study A44104 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2,4,7-Trinitro-fluoren-9-one in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 300390
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0231) of 2,4,7-Trinitro-fluoren-9-one (129-79-3) in F344 Rats Exposed via Gavage, Intravenous Injection, Dermal or, Intraintestinal Administration