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Divinylbenzene (1321-74-0)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2025216


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Divinylbenzene (1321-74-0).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Divinylbenzene (1321-74-0).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative
View
  • Negative

Citation Information


NTP. Divinylbenzene (1321-74-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-534 Toxicology and Carcinogenesis Studies of Divinylbenzene-HP (CASRN 1321-74-0) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C88004B) of Divinylbenzene (1321-74-0) in F344/N Rats via Whole Body Respiratory Exposure
2-Week Evaluation of the Toxicity (C88004B) of Divinylbenzene (1321-74-0) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C88004B) of Divinylbenzene (1321-74-0) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
2-Week Evaluation of the Toxicity (C88004B) of Divinylbenzene (1321-74-0) in B6C3F1 Mice via Whole Body Respiratory Exposure
2-Week Evaluation of the Toxicity (C88004B) of Divinylbenzene (1321-74-0) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C88004B) of Divinylbenzene (1321-74-0) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C88004B) of Divinylbenzene (1321-74-0) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C88004B) of Divinylbenzene (1321-74-0) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C88004B) of Divinylbenzene (1321-74-0) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C88004B) of Divinylbenzene (1321-74-0) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Divinylbenzene (1321-74-0) in Micronucleus Study A22394 in B6C3F1 Mice
Genetic Toxicity Evaluation of Divinylbenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 281912
Summary Data
Genetic Toxicity Evaluation of Divinylbenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 563294
Summary Data
Genetic Toxicity Evaluation of Divinylbenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A67622
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0149) of Divinylbenzene (1321-74-0) in F344 Rats Exposed via Intravenous or Gavage Administration