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Tenofovir (147127-20-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9040132

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Tenofovir (147127-20-6).
Micronucleus - Mice
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  • Male: Negative
    Female: Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Tenofovir (147127-20-6).
Bacterial Mutagenicity
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  • Positive

Citation Information

NTP. Tenofovir (147127-20-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Hobbs CA, Recio L, Shepard K, Baldetti C, Winters J, Caspary, W, Witt KL. Abstract, presented at the EMS Annual Meeting in Atlanta GA, October 20-24, 2007. Gender-Specific Genotoxicity in Mice Treated with Emtricitabine and Tenofovir as Assessed by the Flow Cytometry Micronucleus and Comet Assays.

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Tenofovir (147127-20-6) in Micronucleus Study F27464 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Tenofovir in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A94329
Summary Data

DTT Data Collections