U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

6-Thioguanine (154-42-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6023652

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 6-Thioguanine (154-42-7).
Micronucleus - Mice
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 6-Thioguanine (154-42-7).
Mammalian Cell Cytogenetics
CA
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 6-Thioguanine (154-42-7).
Bacterial Mutagenicity
View
  • Negative
View
  • Positive

Citation Information

NTP. 6-Thioguanine (154-42-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 6-Thioguanine (6-TG) (154-42-7) in Micronucleus Study 414883 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 6-Thioguanine (6-TG) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 024759
Summary Data
Genetic Toxicity Evaluation of 6-Thioguanine (6-TG) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A64894
Summary Data

NTP Data Collections