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6-Thioguanine (154-42-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6023652

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 6-Thioguanine (154-42-7).
Micronucleus - Mice
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 6-Thioguanine (154-42-7).
Mammalian Cell Cytogenetics
CA
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 6-Thioguanine (154-42-7).
Bacterial Mutagenicity
View
  • Negative
View
  • Positive

Citation Information

NTP. 6-Thioguanine (154-42-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 6-Thioguanine (6-TG) (154-42-7) in Micronucleus Study 414883 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 6-Thioguanine (6-TG) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 024759
Summary Data
Genetic Toxicity Evaluation of 6-Thioguanine (6-TG) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A64894
Summary Data

DTT Data Collections