5-Amino-o-cresol (2835-95-2)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9024489
Publications
TOX-89
Toxicity Studies of 5-Amino-o-cresol Administered Dermally to F344/NTac Rats and B6C3F1/N Mice (CASRN 2835-95-2)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Witt KL, Livanos E, Kissling GE, Torous DK, Caspary W, Tice RR, Recio L. Comparison of flow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals. Mutat Res. 2008 Jan 8;649(1-2):101-13. Epub 2007 Aug 11.
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C20214) of 5-Amino-o-cresol (2835-95-2) in F344/N Tac Rats Exposed via Topical Application
3-Month Study Tables
- E03 - Growth Curves (62 kB)
- E04 - Mean Body Weights and Survival Table (18 kB)
- E05 - Clinical Observations Summary (18 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 kB)
- P04 - Neoplasms by Individual Animal (206 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (216 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (144 kB)
- P14 - Individual Animal Pathology Data (269 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35 kB)
- P40 - Survival Curves (59 kB)
3-Month Individual Animal Data
- Female Individual Animal Body Weight Data (35 kB)
- Female Individual Animal Clinical Observations (4 kB)
- Female Individual Animal Non Neoplastic Pathology Data (44 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Animal Body Weight Data (35 kB)
- Male Individual Animal Clinical Observations (3 kB)
- Male Individual Animal Non Neoplastic Pathology Data (47 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal_Body Weight Data (19 kB)
3-Month Evaluation of the Toxicity (C20214) of 5-Amino-o-cresol (2835-95-2) in B6C3F1 Mice Exposed via Topical Application
3-Month Study Tables
- E03 - Growth Curves (65 kB)
- E04 - Mean Body Weights and Survival Table (18 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (29 kB)
- P04 - Neoplasms by Individual Animal (218 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (219 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (98 kB)
- P14 - Individual Animal Pathology Data (262 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (30 kB)
- P40 - Survival Curves (59 kB)
3-Month Individual Animal Data
- Female Individual Animal Body Weight Data (34 kB)
- Female Individual Animal Clinical Observations (2 kB)
- Female Individual Animal Neoplastic Pathology Data (2 kB)
- Female Individual Animal Non Neoplastic Pathology Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Animal Body Weight Data (34 kB)
- Male Individual Animal Clinical Observations (2 kB)
- Male Individual Animal Non Neoplastic Pathology Data (13 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal_Body Weight Data (18 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of 5-Amino-o-cresol (2835-95-2) in Micronucleus Study A04294 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 5-Amino-o-cresol (2835-95-2) in Micronucleus Study A62651 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 5-Amino-o-cresol (2835-95-2) in Micronucleus Study F62651 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 5-Amino-o-cresol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 576026
Summary Data
- G06 - Ames Summary Data (138 KB)