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Glyphosate Isopropylamine Salt (38641-94-0)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0034649

Study Results

Genetic Toxicology

An overview of Genetic Toxicology In Vitro Micronucleus study conclusions related to Glyphosate Isopropylamine Salt (38641-94-0).
In Vitro Micronucleus
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  • Positive
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  • Negative
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  • Weakly Positive
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  • Negative
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  • Weakly Positive
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  • Equivocal
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  • Equivocal
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  • Negative
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  • Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Glyphosate Isopropylamine Salt (38641-94-0).
Bacterial Mutagenicity
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  • Negative
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  • Negative
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  • Negative
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  • Negative
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  • Negative
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  • Negative
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  • Negative
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  • Negative
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  • Negative

Citation Information

NTP. Glyphosate Isopropylamine Salt (38641-94-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Comparative investigation of the potential of glyphosate and glyphosate-based formulations (GBFs) to cause oxidative stress and DNA damage in human skin and liver cell systems Stephanie L. Smith-Roe1, Michael J. DeVito1, Caroll Co2, Sreenivasa C. Ramaiahgari1, Michael Easterling2, Julie R. Rice1, Paul E. Dunlap1, David M. Crizer1, Zhifeng Zhou1, B. Alex Merrick1, Guanhua Xie2, Shawn F. Harris2, Keith R. Shockley3, Arpit Tandon4, Ayse Oktay4, Deepak Mav4, Ruchir Shah4, Alexandre Borrel4, Vijay Gombar4, Scott A. Masten1, Richard S. Paules1, Stephen S. Ferguson1*

Affiliations
1Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
2DLH, LLC, Bethesda, Maryland, USA.
3Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
4Sciome, Durham, North Carolina, USA.

*Corresponding Author
Stephen S. Ferguson, Ph.D.
Mechanistic Toxicology Branch
Division of Translational Toxicology
National Institute of Environmental Health Sciences
111 TW Alexander Dr.
Building 101, Room E140B
P.O. Box 12233
Research Triangle Park, NC 27709
Email: stephen.ferguson@nih.gov; (984)287-3128

DOI: https://doi.org/10.22427/NTP-DATA-500-106-001-000-3
Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate-based formulations for genotoxic activity using in vitro assays Stephanie L. Smith-Roe, Carol D. Swartz, Asma Rashid, Nicholas C. Christy, Jamie E. Sly, Xiaoqing Chang, Nisha S. Sipes, Keith R. Shockley, Shawn F. Harris, Sandra J. McBride, Gary J. Larson, Bradley J. Collins, Esra Mutlu, Kristine L. Witt

Environmental and Molecular Mutagenesis: https://onlinelibrary.wiley.com/doi/10.1002/em.22534
DOI: https://doi.org/10.22427/NTP-DATA-002-02220-0014-0000-3

Two data values for one concentration in the 4 h +S9 experimental condition were corrected after a quality assurance audit. This finding did not impact the interpretation of the study.

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Buccaneer Plus (38641-94-0) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G18022 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Buccaneer Plus (38641-94-0) in Micronucleus Study G18022C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Buccaneer Plus (38641-94-0) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G18022B
Summary Data
Genetic Toxicity Evaluation of Cornerstone Plus (38641-94-0) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G18023 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Cornerstone Plus (38641-94-0) in Micronucleus Study G18023C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Cornerstone Plus (38641-94-0) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G18023B
Summary Data
Genetic Toxicity Evaluation of Glyphosate isopropylamine salt (38641-94-0) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G88205 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Glyphosate isopropylamine salt (38641-94-0) in Micronucleus Study G88205C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Glyphosate isopropylamine salt (38641-94-0) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G88205B
Summary Data
Genetic Toxicity Evaluation of Glystar Plus (38641-94-0) in Micronucleus Study G18025C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Glystar Plus (38641-94-0) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G18025B
Summary Data
Genetic Toxicity Evaluation of Glystar Plus(38641-94-0) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G18025 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Hi-Yield KILLZALL II (38641-94-0) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G18033 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Hi-Yield KILLZALL II (38641-94-0) in Micronucleus Study G18033C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Hi-Yield KILLZALL II (38641-94-0) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G18033B
Summary Data
Genetic Toxicity Evaluation of Remuda Full Strength (38641-94-0) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G18034 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Remuda Full Strength (38641-94-0) in Micronucleus Study G18034C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Remuda Full Strength (38641-94-0) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G18034B
Summary Data
Genetic Toxicity Evaluation of Roundup Concentrate Plus (38641-94-0) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G18031 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Roundup Concentrate Plus (38641-94-0) in Micronucleus Study G18031C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Roundup Concentrate Plus (38641-94-0) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G18031B
Summary Data
Genetic Toxicity Evaluation of Roundup Custom (38641-94-0) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G18027 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Roundup Custom (38641-94-0) in Micronucleus Study G18027C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Roundup Custom (38641-94-0) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G18027B
Summary Data
Genetic Toxicity Evaluation of Roundup Super Concentrate (38641-94-0) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G18032 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Roundup Super Concentrate (38641-94-0) in Micronucleus Study G18032C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Roundup Super Concentrate (38641-94-0) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G18032B
Summary Data

DTT Data Collections