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1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (57653-85-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0023824

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Equivocal, Male, Rats
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  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Negative, Male, Mice
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  • Positive, Male, Mice
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  • Positive, Female, Mice
View
  • Negative, Female, Mice

Citation Information

NTP. 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (57653-85-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-198 Bioassay of a Mixture of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin and 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (Gavage) for Possible Carcinogenicity (CASRN 57653-85-7, CASRN 19408-74-3)
TR-202 Bioassay of a Mixture of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin and 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (Dermal Study) for Possible Carcinogenicity (CASRN 57653-85-7; CASRN 19408-74-3)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (57653-85-7) in Male Osborne-Mendel Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (57653-85-7) in Female Osborne-Mendel Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (57653-85-7) in Male B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (57653-85-7) in Female B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (57653-85-7) in Male Swiss-Webster Mice Exposed via Topical Application
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (57653-85-7) in Female Swiss-Webster Mice Exposed via Topical Application
Individual Animal Data

Other NTP Studies

1-Day Immunotoxicity Evaluation (IMM84001, PROBE-TCDD-1-1-PO) of 1,2,3,6,7,8-Hexachlorodibenzo-p-Dioxin (57653-85-7) in B6C3F1 Mice via Gavage
B6CF1 Mice Individual and Summary Data

NTP Data Collections