Pyrimethamine (58-14-0)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9021217
Study Results
Chronic Bioassay Level of Evidence
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Mice | |
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Genetic Toxicology
Mammalian Cell Cytogenetics | |
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CA | SCE |
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Bacterial Mutagenicity |
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Publications
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of Pyrimethamine (58-14-0) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Pyrimethamine (58-14-0) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Pyrimethamine (58-14-0) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Pyrimethamine (58-14-0) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Pyrimethamine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 368591
Summary Data
- G06 - Ames Summary Data (141 KB)
Other NTP Studies
28-Day Immunotoxicity Evaluation (IMM96013) of AZT + Pyrimethamine Combination (Aids) (AZT/PYRIMETH) in B6C3F1 Mice via Gavage
B6CF1 Mice Individual and Summary Data
- Absolute Leukocyte Differentials (14 kB)
- Body Weights (52 kB)
- Hematology (17 kB)
- In Vitro Cytotoxic T Lymphocyte (CTL) Assay (16 kB)
- Mixed Leukocyte Response (12 kB)
- Natural Killer Activity (18 kB)
- Organ Weights (19 kB)
- Reticulocytes (10 kB)
- Reticuloendothelial System (25 kB)
- Serum IgM (17 kB)
- T-Dependent AB Response Day 4 (26 kB)