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Methyl isocyanate (624-83-9)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1023786

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Methyl isocyanate (624-83-9).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Methyl isocyanate (624-83-9).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Methyl isocyanate (624-83-9).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Methyl isocyanate (624-83-9).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Methyl isocyanate (624-83-9).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information

NTP. Methyl isocyanate (624-83-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Tice, R.R., Luke, C.A., and Shelby, M.D. Methyl isocyanate: An evalution of in vivo cytogenetic activity. Environ. Mutagen. Vol. 9 (1987) 37-58
Mason, J.M., Zeiger, E., Haworth, S., Ivette, J., Valencia, R. Genotoxicity studies of methyl isocyanate in Salmonella, Drosphila, and cultured Chinese hamster ovary cells Environ. Mutagen. Vol. 9 (1987) 19-28
Tice, R.R., Luke, C.A., and Shelby, M.D. Methyl isocyanate: An evalution of in vivo cytogenetic activity. Environ. Mutagen. Vol. 9 (1987) 37-58
Caspary, W., and Myhr, B. Mutagenicity of MIC and its reaction products to cultured mammalian cells. Mutation Res. Vol. 174 (1986) 285-293
Mason, J., Zeiger, E., Haworth, S., Ivett, J., and Valencia, R. Genotoxicity studies of methyl isocyanate in Salmonella, Drosophila, and cultured Chinese hamster ovary cells. Environ. Mutagen. Vol. 9 (1987) 19-28
Mason, J., Zeiger, E., Haworth, S., Ivett, J., and Valencia, R. Genotoxicity studies of methyl isocyanate in Salmonella, Drosophila, and cultured Chinese hamster ovary cells. Environ. Mutagen. Vol. 9 (1987) 19-28

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Methyl Isocyanate (624-83-9) in Micronucleus Study A97304 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Methyl Isocyanate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 290825
Summary Data
Genetic Toxicity Evaluation of Methyl Isocyanate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 327434
Summary Data

DTT Data Collections