p-Toluenesulfonamide (70-55-3)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID8029105
Publications
TOX-88
Toxicity Studies of p-Toluenesulfonamide (CAS No. 70-55-3) Administered in Feed to F344/N Rats,F344/NTac Rats, and B6C3F1/N Mice
Study Data
Toxicity and Carcinogenicity Studies
2-Week Evaluation of the Toxicity (C20301) of p-Toluenesulfonamide (70-55-3) in F344/NTac Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C20301) of p-Toluenesulfonamide (70-55-3) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C20301) of p-Toluenesulfonamide (70-55-3) in F344/NTac Rats Exposed via Dosed Feed
Study Tables
- E03 - Growth Curves (459 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (22 kB)
- E08 - Feed Water and Compound Consumption Table (30 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (32 kB)
- P04 - Neoplasms by Individual Animal (113 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (32 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (118 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (85 kB)
- P14 - Individual Animal Pathology Data (210 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (33 kB)
- P40 - Survival Curves (471 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (35 kB)
- Female Individual Animal Clinical Observations (4 kB)
- Female Individual Animal Non Neoplastic Pathology Data (15 kB)
- Female Individual Animal Organ Weight Data (35 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (35 kB)
- Male Individual Animal Clinical Observations (5 kB)
- Male Individual Animal Non Neoplastic Pathology Data (19 kB)
- Male Individual Animal Organ Weight Data (35 kB)
- Male Individual Animal Survival Data (11 kB)
3-Month Evaluation of the Toxicity (C20301) of p-Toluenesulfonamide (70-55-3) in B6C3F1 Mice Exposed via Dosed Feed
Study Tables
- E03 - Growth Curves (426 kB)
- E04 - Mean Body Weights and Survival Table (23 kB)
- E05 - Clinical Observations Summary (19 kB)
- E08 - Feed Water and Compound Consumption Table (24 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (30 kB)
- P04 - Neoplasms by Individual Animal (116 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (32 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (118 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (61 kB)
- P14 - Individual Animal Pathology Data (211 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (31 kB)
- P40 - Survival Curves (439 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (34 kB)
- Female Individual Animal Clinical Observations (2 kB)
- Female Individual Animal Non Neoplastic Pathology Data (11 kB)
- Female Individual Animal Organ Weight Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (34 kB)
- Male Individual Animal Clinical Observations (3 kB)
- Male Individual Animal Non Neoplastic Pathology Data (9 kB)
- Male Individual Animal Organ Weight Data (19 kB)
- Male Individual Animal Survival Data (11 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of p-Toluenesulfonamide (70-55-3) in Micronucleus Study F66788 in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of p-Toluenesulfonamide (70-55-3) in Micronucleus Study F79645 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of p-Toluenesulfonamide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A84238
Summary Data
- G06 - Ames Summary Data (57 KB)