Sodium nitrite (7632-00-0)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0020941
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
| Micronucleus - Mice |
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| Micronucleus - Rats |
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| Bacterial Mutagenicity |
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Publications
TR-495
Toxicology and Carcinogenesis Studies of Sodium Nitrite (CASRN 7632-00-0) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344 Rats Exposed via Dosed Water. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
Individual Animal Data
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C88007) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C88007B) of Sodium Nitrite (7632-00-0) in F344/N Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C88007B) of Sodium Nitrite (7632-00-0) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A10342 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A17282 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Sodium Nitrite (7632-00-0) in Micronucleus Study A52858 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Sodium Nitrite in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 359703
Summary Data
- G06 - Ames Summary Data (65 KB)
Other NTP Studies
Toxicokinetic Evaluation (S0548) of Sodium nitrite (DTXSID0020941) in Rat and Mouse
Data
- Annotated Group Parameters (20 kB)
- Annotated Individual Animal Data (294 kB)
- Original Data (103 kB)
- Summary Data - Mice, Methemglobin (112 kB)
- Summary Data - Mice, Nitrite (120 kB)
- Summary Data - Rats, Methemglobin (111 kB)
- Summary Data - Rats, Nitrite (122 kB)