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Pyrazinamide (98-96-4)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9021215

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Negative, Male, Rats
View
  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Negative, Male, Mice
View
  • Inadequate Study, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Pyrazinamide (98-96-4).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. Pyrazinamide (98-96-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-048 Bioassay of Pyrazinamide for Possible Carcinogenicity (CASRN 98-96-4)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Pyrazinamide (98-96-4) in Male F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Pyrazinamide (98-96-4) in Female F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Pyrazinamide (98-96-4) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Pyrazinamide (98-96-4) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Pyrazinamide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 511918
Summary Data

DTT Data Collections