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AZT+3TC combination (AZT3TCCOMBO)

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to AZT+3TC combination (AZT3TCCOMBO).
Micronucleus - Mice
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  • Male: Negative
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  • Male: Positive
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  • Male: Positive
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  • Male: Positive
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  • Male: Negative
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  • Male: Negative

Citation Information

NTP. AZT+3TC combination (AZT3TCCOMBO). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT; CASRN 30516-87-1) and (-)2',3'-Dideoxy-3'-thiacytidine (3TC; CASRN 134678-17-4) Co-administered by Gavage to Swiss Albino (CD-1®) Mice on Gestational Days 6 Through 16
Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT; CASRN 30516-87-1) and (-) 2', 3'-Dideoxy-3'-thiacytidine (3TC; CASRN 134678-17-4) Co-administered by Gavage to Swiss Albino (CD-1®) Mice on Gestational Days 6 through 16

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of AZT+3TC+NVP Combination (AZT3TCCOMBO) in Micronucleus Study A40581 in CD-1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of AZT+3TC+NVP Combination (AZT3TCCOMBO) in Micronucleus Study A62246 in CD-1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of AZT+3TC+NVP Combination (AZT3TCCOMBO) in Micronucleus Study A62527 in CD-1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of AZT+3TC+NVP Combination (AZT3TCCOMBO) in Micronucleus Study A75317 in CD-1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of AZT+3TC+NVP Combination (AZT3TCCOMBO) in Micronucleus Study A78223 in CD-1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of AZT+3TC+NVP Combination (AZT3TCCOMBO) in Micronucleus Study A83804 in CD-1 Mice
Summary and Individual Animal Data

Other NTP Studies

Prenatal Developmental Toxicity Pilot Study (TRP20202) of AZT+3TC+NVP Combination (AZT3TCCOMBO) in Swiss CD-1 Mice Exposed via Gavage
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER20203) of AZT+3TC+NVP combination (AZT3TCCOMBO) in Swiss CD-1 Mice Exposed via Gavage
Individual and Summary Data

NTP Data Collections