TOX-102: Toxicity Report Tables & Curves
Pathology Tables, Survival and Growth Curves from NTP
Short-Term, Genetic Toxicology Studies
DOI:
https://doi.org/10.22427/NTP-DATA-TOX-102
Footnotes were updated on 4/17/2020 to clarify which statistical tests were applied to the various endpoints.
Tissue Concentration (PA48) was updated on 11/23/2020 to correct study days.
Vaginal Cytology Markov Model files added on 1/23/2021
Footnotes were updated on 4/17/2020 to clarify which statistical tests were applied to the various endpoints.
Tissue Concentration (PA48) was updated on 11/23/2020 to correct study days.
Vaginal Cytology Markov Model files added on 1/23/2021
TOX-102: Resveratrol
Short-Term
Two-Week Study in F344/NTac Rats
- E01 - Animal Removal Summary By Treatment Group (12 KB)
- E02 - Animals Removed from Experiment (59 KB)
- E03 - Growth Curves (330 KB)
- E04 - Mean Body Weights and Survival Table (11 KB)
- E05 - Clinical Observations Summary (10 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (16 KB)
- P04 - Neoplasms by Individual Animal (111 KB)
- P08 - Statistical Analysis of Primary Tumors (8 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (43 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (14 KB)
- P14 - Individual Animal Pathology Data (76 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (17 KB)
- P22 - Cause of Death Summary (8 KB)
- P40 - Survival Curves (386 KB)
- PA06 - Organ Weights Summary (98 KB)
Two-Week Study in F344/NTac Rats- Individual Animal Data
- Female Individual Animal Body Weight Data All Animals (9 KB)
- Female Individual Animal Non Neoplastic Pathology Data (3 KB)
- Female Individual Animal Survival Data (6 KB)
- Female Individual Animal Terminal Body Weight Data (10 KB)
- Male Individual Animal Body Weight Data All Animals (9 KB)
- Male Individual Animal Non Neoplastic Pathology Data (3 KB)
- Male Individual Animal Survival Data (6 KB)
- Male Individual Animal Terminal Body Weight Data (10 KB)
Two-Week Study in B6C3F1N Mice
- E01 - Animal Removal Summary By Treatment Group (8 KB)
- E02 - Animals Removed from Experiment (42 KB)
- E03 - Growth Curves (331 KB)
- E04 - Mean Body Weights and Survival Table (11 KB)
- E05 - Clinical Observations Summary (8 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (16 KB)
- P04 - Neoplasms by Individual Animal (112 KB)
- P08 - Statistical Analysis of Primary Tumors (8 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (43 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (14 KB)
- P14 - Individual Animal Pathology Data (76 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (16 KB)
- P22 Cause of Death Summary (8 KB)
- P40 - Survival Curves (385 KB)
- PA06 - Organ Weights Summary (98 KB)
Two-Week Study in B6C3F1N Mice- Individual Animal Data
- Female Individual Animal Body Weight Data All Animals (9 KB)
- Female Individual Animal Non Neoplastic Pathology Data (2 KB)
- Female Individual Animal Survival Data (6 KB)
- Female Individual Animal Terminal Body Weight Data (10 KB)
- Male Individual Animal Body Weight Data All Animals (9 KB)
- Male Individual Animal Non Neoplastic Pathology Data (2 KB)
- Male Individual Animal Survival Data (6 KB)
- Male Individual Animal Terminal Body Weight Data (10 KB)
Perinatal and Three-Month Study in Wistar Han Rats
- E01 - Animal Removal Summary By Treatment Group (7 KB)
- E02 - Animals Removed from Experiment (45 KB)
- E03 - Growth Curves (62 KB)
- E04 - Mean Body Weights and Survival Table (13 KB)
- E05 - Clinical Observations Summary (6 KB)
- E12 - Animal History (245 KB)
- Gestational Body Weight Changes (g) (20 KB)
- Gestational Body Weights (g) (23 KB)
- Lactational Body Weight Changes (g) (18 KB)
- Lactational Body Weights (g) (24 KB)
- Litter Size and Survival (26 KB)
- P03 Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (26 KB)
- P04 Neoplasms by Individual Animal (190 KB)
- P05 Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (26 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (198 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (123 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Litter based (123 KB)
- P14 - Individual Animal Pathology Data (233 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (27 KB)
- P40 - Survival Curves (53 KB)
- PA06 - Organ Weights Summary (99 KB)
- PA41 - Clinical Chemistry Summary (239 KB)
- PA43 - Hematology Summary (260 KB)
- PA48 - Summary of Tissue Concentration (110 KB)
- PND 1 Data (24 KB)
- Pup Body Weights (g) (26 KB)
- R02 - Reproductive Performance Summary (41 KB)
- R06 - Andrology Summary (47 KB)
- Vaginal Cytology Markov Model (169 KB)
- Vaginal Cytology Plots (271 KB)
- Vaginal Cytology Summary (25 KB)
Perinatal and Three-Month Study in Wistar Han Rats- Individual Animal Data
- Female Individual Animal Body Weight Data All Animals (35 KB)
- Female Individual Animal Non Neoplastic Pathology Data (35 KB)
- Female Individual Animal Survival Data (11 KB)
- Female Individual Animal Terminal Body Weight Data (18 KB)
- Individual Animal Andrology Data (8 KB)
- Individual Animal Clinical Chemistry Data (14 KB)
- Individual Animal DamID and PupID Data (8 KB)
- Individual Animal Hematology Data (17 KB)
- Individual Animal Organ Weight Data (12 KB)
- Individual Animal Reproductive Performance Data (11 KB)
- Individual Animal Tissue Concentration Data (38 KB)
- Male Individual Animal Body Weight Data All Animals (35 KB)
- Male Individual Animal Non Neoplastic Pathology Data (41 KB)
- Male Individual Animal Survival Data (11 KB)
- Male Individual Animal Terminal Body Weight Data (18 KB)
Three-Month Study in B6C3F1/N Mice
- E03 - Growth Curves (438 KB)
- E04 - Mean Body Weights and Survival Table (17 KB)
- E05 - Clinical Observations Summary (11 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (32 KB)
- P04 - Neoplasms by Individual Animal (201 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (33 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (207 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (107 KB)
- P14 - Individual Animal Pathology Data (261 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (33 KB)
- P40 - Survival Curves (435 KB)
- PA06 - Organ Weights Summary (85 KB)
- PA43 - Hematology Summary (293 KB)
- R06 - Andrology Summary (47 KB)
- Vaginal Cytology Markov Model (187 KB)
- Vaginal Cytology Plots (274 KB)
- Vaginal Cytology Summary (183 KB)
Three-Month Study in B6C3F1/N Mice- Individual Animal Data
- Female Individual Animal Body Weight Data All Animals (34 KB)
- Female Individual Animal Non Neoplastic Pathology Data (35 KB)
- Female Individual Animal Survival Data (11 KB)
- Female Individual Animal Terminal Body Weight Data (18 KB)
- Individual Animal Andrology Data (8 KB)
- Individual Animal Hematology Data (18 KB)
- Individual Animal Organ Weight Data (11 KB)
- Male Individual Animal Body Weight Data All Animals (34 KB)
- Male Individual Animal Non Neoplastic Pathology Data (24 KB)
- Male Individual Animal Survival Data (11 KB)
- Male Individual Animal Terminal Body Weight Data (18 KB)
Genetic Toxicology
Genetic Toxicity Evaluation of Resveratrol (501-36-0) in Micronucleus Study G01090 in Wistar Han Rat
Genetic Toxicity Evaluation of Resveratrol (501-36-0) in Micronucleus Study G01090B in B6C3F1 Mice
Genetic Toxicity Evaluation of Resveratrol in Salmonella/E.coli Mutagenicity Test or Ames Test Study
- G06 - Ames Summary Data (55 KB)