TR-571: Technical Report Pathology Tables and Curves

Pathology Tables, Survival and Growth Curves from NTP
Short-Term, Long-Term Studies

TR-571: Kava Kava extract

Short-Term

2-Week Study Tables - Rats

• E01 - Animal Removal Summary By Treatment Group (117 KB)
• E03 - Growth Curves (136 KB)
• E04 - Mean Body Weights and Survival Table (122 KB)
• E05 - Clinical Observations Summary (27 KB)
• E08 - Feed Water and Compound Consumption Table (358 KB)
• P02 - Incidence Rates of Neoplasms by Anatomic Site (12 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (309 KB)
• P04 - Neoplasms by Individual Animal (15 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (18 KB)
• P07 - Neoplasms by Individual Animal (Systemic Lesions Abridged) (27 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (27 KB)
• P11 - Statistical Analysis of Survival Data (26 KB)
• P14 - Individual Animal Pathology Data (135 KB)
• P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (27 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (27 KB)
• P40 - Survival Curves (135 KB)

2-Week Individual Animal Data - Rats

• Female Individual Animal Body Weight Data (8 KB)
• Female Individual Animal Clinical Observations (9 KB)
• Female Individual Animal Non Neoplastic Pathology Data (25 KB)
• Female Individual Animal Organ Weight Data (18 KB)
• Female Individual Animal Survival Data (6 KB)
• Male Individual Animal Body Weight Data (8 KB)
• Male Individual Animal Clinical Observations (4 KB)
• Male Individual Animal Non Neoplastic Pathology Data (15 KB)
• Male Individual Animal Organ Weight Data (18 KB)
• Male Individual Animal Survival Data (6 KB)

2-Week Study Tables - Mice

• E01 - Animal Removal Summary By Treatment Group (12 KB)
• E03 - Growth Curves (306 KB)
• E04 - Mean Body Weights and Survival Table (15 KB)
• E05 - Clinical Observations Summary (18 KB)
• E08 - Feed Water and Compound Consumption Table (27 KB)
• P02 - Incidence Rates of Neoplasms by Anatomic Site (27 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (22 KB)
• P04 - Neoplasms by Individual Animal (131 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (27 KB)
• P07 - Neoplasms by Individual Animal (Systemic Lesions Abridged) (132 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (73 KB)
• P11 - Statistical Analysis of Survival Data (27 KB)
• P14 - Individual Animal Pathology Data (118 KB)
• P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (132 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (23 KB)
• P40 - Survival Curves (358 KB)

2-Week Individual Animal Data - Mice

• Female Individual Animal Body Weight Data (8 KB)
• Female Individual Animal Clinical Observations (9 KB)
• Female Individual Animal Non Neoplastic Pathology Data (8 KB)
• Female Individual Animal Organ Weight Data (18 KB)
• Female Individual Animal Survival Data (6 KB)
• Male Individual Animal Body Weight Data (8 KB)
• Male Individual Animal Clinical Observations (7 KB)
• Male Individual Animal Non Neoplastic Pathology Data (6 KB)
• Male Individual Animal Organ Weight Data (18 KB)
• Male Individual Animal Survival Data (6 KB)

3-Month Study Tables - Rats

• E01 - Animal Removal Summary By Treatment Group (12 KB)
• E03 - Growth Curves (434 KB)
• E04 - Mean Body Weights and Survival Table (17 KB)
• E05 - Clinical Observations Summary (18 KB)
• P02 - Incidence Rates of Neoplasms by Anatomic Site (33 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 KB)
• P04 - Neoplasms by Individual Animal (230 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (33 KB)
• P07 - Neoplasms by Individual Animal (Systemic Lesions Abridged) (231 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (246 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (211 KB)
• P11 - Statistical Analysis of Survival Data (27 KB)
• P14 - Individual Animal Pathology Data (266 KB)
• P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (231 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35 KB)
• P40 - Survival Curves (429 KB)

3-Month Individual Animal Data - Rats

• Female Individual Animal Body Weight Data (34 KB)
• Female Individual Animal Clinical Observations (9 KB)
• Female Individual Animal Non Neoplastic Pathology Data (38 KB)
• Female Individual Animal Organ Weight Data (26 KB)
• Female Individual Animal Survival Data (11 KB)
• Male Individual Animal Body Weight Data (34 KB)
• Male Individual Animal Clinical Observations (5 KB)
• Male Individual Animal Non Neoplastic Pathology Data (41 KB)
• Male Individual Animal Organ Weight Data (26 KB)
• Male Individual Animal Survival Data (11 KB)

3-Month Study Tables - Mice

• E01 - Animal Removal Summary By Treatment Group (12 KB)
• E03 - Growth Curves (425 KB)
• E04 - Mean Body Weights and Survival Table (17 KB)
• E05 - Clinical Observations Summary (18 KB)
• P02 - Incidence Rates of Neoplasms by Anatomic Site (32 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (32 KB)
• P04 - Neoplasms by Individual Animal (204 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (33 KB)
• P07 - Neoplasms by Individual Animal (Systemic Lesions Abridged) (205 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (207 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (127 KB)
• P11 - Statistical Analysis of Survival Data (27 KB)
• P14 - Individual Animal Pathology Data (263 KB)
• P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (204 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (33 KB)
• P40 - Survival Curves (509 KB)

3-Month Individual Animal Data - Mice

• Female Individual Animal Body Weight Data (33 KB)
• Female Individual Animal Clinical Observations (7 KB)
• Female Individual Animal Non Neoplastic Pathology Data (32 KB)
• Female Individual Animal Organ Weight Data (26 KB)
• Female Individual Animal Survival Data (11 KB)
• Male Individual Animal Body Weight Data (33 KB)
• Male Individual Animal Clinical Observations (7 KB)
• Male Individual Animal Non Neoplastic Pathology Data (32 KB)
• Male Individual Animal Organ Weight Data (26 KB)
• Male Individual Animal Survival Data (11 KB)

Long-Term

Chronic Study Tables - Rats

• E03 - Growth Curves (514 KB)
• E04 - Mean Body Weights and Survival Table (19 KB)
• E05 - Clinical Observations Summary (22 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (55 KB)
• P04 - Neoplasms by Individual Animal (674 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (48 KB)
• P08 - Statistical Analysis of Primary Tumors (217 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (816 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (446 KB)
• P11 - Statistical Analysis of Survival Data (24 KB)
• P14 - Individual Animal Pathology Data (1 MB)
• P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (596 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (56 KB)
• P40 - Survival Curves (513 KB)

Chronic Individual Animal Data - Rats

• Female Individual Animal Body Weight Data (363 KB)
• Female Individual Animal Clinical Observations (167 KB)
• Female Individual Animal Neoplastic Pathology Data (136 KB)
• Female Individual Animal Non Neoplastic Pathology Data (758 KB)
• Female Individual Animal Organ Weight Data (56 KB)
• Female Individual Animal Survival Data (33 KB)
• Male Individual Animal Body Weight Data (320 KB)
• Male Individual Animal Clinical Observations (121 KB)
• Male Individual Animal Neoplastic Pathology Data (185 KB)
• Male Individual Animal Non Neoplastic Pathology Data (855 KB)
• Male Individual Animal Organ Weight Data (55 KB)
• Male Individual Animal Survival Data (33 KB)

Chronic Study Tables - Mice

• E03 - Growth Curves (525 KB)
• E04 - Mean Body Weights and Survival Table (19 KB)
• E05 - Clinical Observations Summary (21 KB)
• P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (48 KB)
• P04 - Neoplasms by Individual Animal (402 KB)
• P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (44 KB)
• P08 - Statistical Analysis of Primary Tumors (199 KB)
• P09 - Non-Neoplastic Lesions by Individual Animal (461 KB)
• P10 - Statistical Analysis of Non-Neoplastic Lesions (430 KB)
• P11 - Statistical Analysis of Survival Data (24 KB)
• P14 - Individual Animal Pathology Data (1 MB)
• P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (384 KB)
• P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (52 KB)
• P40 - Survival Curves (512 KB)

Chronic Individual Animal Data - Mice

• Female Individual Animal Body Weight Data (337 KB)
• Female Individual Animal Clinical Observations (40 KB)
• Female Individual Animal Neoplastic Pathology Data (102 KB)
• Female Individual Animal Non Neoplastic Pathology Data (735 KB)
• Female Individual Animal Organ Weight Data (56 KB)
• Female Individual Animal Survival Data (33 KB)
• Male Individual Animal Body Weight Data (382 KB)
• Male Individual Animal Clinical Observations (47 KB)
• Male Individual Animal Neoplastic Pathology Data (148 KB)
• Male Individual Animal Non Neoplastic Pathology Data (1 MB)
• Male Individual Animal Organ Weight Data (56 KB)
• Male Individual Animal Survival Data (33 KB)