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TR-571: Technical Report Pathology Tables and Curves

Pathology Tables, Survival and Growth Curves from NTP
Short-Term, Long-Term Studies

TR-571: Kava Kava extract

Short-Term

2-Week Study Tables - Rats

E01 - Animal Removal Summary By Treatment Group (117 KB)
E03 - Growth Curves (136 KB)
E04 - Mean Body Weights and Survival Table (122 KB)
E05 - Clinical Observations Summary (27 KB)
E08 - Feed Water and Compound Consumption Table (358 KB)
P02 - Incidence Rates of Neoplasms by Anatomic Site (12 KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (309 KB)
P04 - Neoplasms by Individual Animal (15 KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (18 KB)
P07 - Neoplasms by Individual Animal (Systemic Lesions Abridged) (27 KB)
P09 - Non-Neoplastic Lesions by Individual Animal (27 KB)
P11 - Statistical Analysis of Survival Data (26 KB)
P14 - Individual Animal Pathology Data (135 KB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (27 KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (27 KB)
P40 - Survival Curves (135 KB)

2-Week Individual Animal Data - Rats

Female Individual Animal Body Weight Data (8 KB)
Female Individual Animal Clinical Observations (9 KB)
Female Individual Animal Non Neoplastic Pathology Data (25 KB)
Female Individual Animal Organ Weight Data (18 KB)
Female Individual Animal Survival Data (6 KB)
Male Individual Animal Body Weight Data (8 KB)
Male Individual Animal Clinical Observations (4 KB)
Male Individual Animal Non Neoplastic Pathology Data (15 KB)
Male Individual Animal Organ Weight Data (18 KB)
Male Individual Animal Survival Data (6 KB)

2-Week Study Tables - Mice

E01 - Animal Removal Summary By Treatment Group (12 KB)
E03 - Growth Curves (306 KB)
E04 - Mean Body Weights and Survival Table (15 KB)
E05 - Clinical Observations Summary (18 KB)
E08 - Feed Water and Compound Consumption Table (27 KB)
P02 - Incidence Rates of Neoplasms by Anatomic Site (27 KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (22 KB)
P04 - Neoplasms by Individual Animal (131 KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (27 KB)
P07 - Neoplasms by Individual Animal (Systemic Lesions Abridged) (132 KB)
P09 - Non-Neoplastic Lesions by Individual Animal (73 KB)
P11 - Statistical Analysis of Survival Data (27 KB)
P14 - Individual Animal Pathology Data (118 KB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (132 KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (23 KB)
P40 - Survival Curves (358 KB)

2-Week Individual Animal Data - Mice

Female Individual Animal Body Weight Data (8 KB)
Female Individual Animal Clinical Observations (9 KB)
Female Individual Animal Non Neoplastic Pathology Data (8 KB)
Female Individual Animal Organ Weight Data (18 KB)
Female Individual Animal Survival Data (6 KB)
Male Individual Animal Body Weight Data (8 KB)
Male Individual Animal Clinical Observations (7 KB)
Male Individual Animal Non Neoplastic Pathology Data (6 KB)
Male Individual Animal Organ Weight Data (18 KB)
Male Individual Animal Survival Data (6 KB)

3-Month Study Tables - Rats

E01 - Animal Removal Summary By Treatment Group (12 KB)
E03 - Growth Curves (434 KB)
E04 - Mean Body Weights and Survival Table (17 KB)
E05 - Clinical Observations Summary (18 KB)
P02 - Incidence Rates of Neoplasms by Anatomic Site (33 KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 KB)
P04 - Neoplasms by Individual Animal (230 KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (33 KB)
P07 - Neoplasms by Individual Animal (Systemic Lesions Abridged) (231 KB)
P09 - Non-Neoplastic Lesions by Individual Animal (246 KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (211 KB)
P11 - Statistical Analysis of Survival Data (27 KB)
P14 - Individual Animal Pathology Data (266 KB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (231 KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35 KB)
P40 - Survival Curves (429 KB)

3-Month Individual Animal Data - Rats

Female Individual Animal Body Weight Data (34 KB)
Female Individual Animal Clinical Observations (9 KB)
Female Individual Animal Non Neoplastic Pathology Data (38 KB)
Female Individual Animal Organ Weight Data (26 KB)
Female Individual Animal Survival Data (11 KB)
Male Individual Animal Body Weight Data (34 KB)
Male Individual Animal Clinical Observations (5 KB)
Male Individual Animal Non Neoplastic Pathology Data (41 KB)
Male Individual Animal Organ Weight Data (26 KB)
Male Individual Animal Survival Data (11 KB)

3-Month Study Tables - Mice

E01 - Animal Removal Summary By Treatment Group (12 KB)
E03 - Growth Curves (425 KB)
E04 - Mean Body Weights and Survival Table (17 KB)
E05 - Clinical Observations Summary (18 KB)
P02 - Incidence Rates of Neoplasms by Anatomic Site (32 KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (32 KB)
P04 - Neoplasms by Individual Animal (204 KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (33 KB)
P07 - Neoplasms by Individual Animal (Systemic Lesions Abridged) (205 KB)
P09 - Non-Neoplastic Lesions by Individual Animal (207 KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (127 KB)
P11 - Statistical Analysis of Survival Data (27 KB)
P14 - Individual Animal Pathology Data (263 KB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (204 KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (33 KB)
P40 - Survival Curves (509 KB)

3-Month Individual Animal Data - Mice

Female Individual Animal Body Weight Data (33 KB)
Female Individual Animal Clinical Observations (7 KB)
Female Individual Animal Non Neoplastic Pathology Data (32 KB)
Female Individual Animal Organ Weight Data (26 KB)
Female Individual Animal Survival Data (11 KB)
Male Individual Animal Body Weight Data (33 KB)
Male Individual Animal Clinical Observations (7 KB)
Male Individual Animal Non Neoplastic Pathology Data (32 KB)
Male Individual Animal Organ Weight Data (26 KB)
Male Individual Animal Survival Data (11 KB)

Long-Term

Chronic Study Tables - Rats

E03 - Growth Curves (514 KB)
E04 - Mean Body Weights and Survival Table (19 KB)
E05 - Clinical Observations Summary (22 KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (55 KB)
P04 - Neoplasms by Individual Animal (674 KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (48 KB)
P08 - Statistical Analysis of Primary Tumors (217 KB)
P09 - Non-Neoplastic Lesions by Individual Animal (816 KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (446 KB)
P11 - Statistical Analysis of Survival Data (24 KB)
P14 - Individual Animal Pathology Data (1 MB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (596 KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (56 KB)
P40 - Survival Curves (513 KB)

Chronic Individual Animal Data - Rats

Female Individual Animal Body Weight Data (363 KB)
Female Individual Animal Clinical Observations (167 KB)
Female Individual Animal Neoplastic Pathology Data (136 KB)
Female Individual Animal Non Neoplastic Pathology Data (758 KB)
Female Individual Animal Organ Weight Data (56 KB)
Female Individual Animal Survival Data (33 KB)
Male Individual Animal Body Weight Data (320 KB)
Male Individual Animal Clinical Observations (121 KB)
Male Individual Animal Neoplastic Pathology Data (185 KB)
Male Individual Animal Non Neoplastic Pathology Data (855 KB)
Male Individual Animal Organ Weight Data (55 KB)
Male Individual Animal Survival Data (33 KB)

Chronic Study Tables - Mice

E03 - Growth Curves (525 KB)
E04 - Mean Body Weights and Survival Table (19 KB)
E05 - Clinical Observations Summary (21 KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (48 KB)
P04 - Neoplasms by Individual Animal (402 KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (44 KB)
P08 - Statistical Analysis of Primary Tumors (199 KB)
P09 - Non-Neoplastic Lesions by Individual Animal (461 KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (430 KB)
P11 - Statistical Analysis of Survival Data (24 KB)
P14 - Individual Animal Pathology Data (1 MB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (384 KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (52 KB)
P40 - Survival Curves (512 KB)

Chronic Individual Animal Data - Mice

Female Individual Animal Body Weight Data (337 KB)
Female Individual Animal Clinical Observations (40 KB)
Female Individual Animal Neoplastic Pathology Data (102 KB)
Female Individual Animal Non Neoplastic Pathology Data (735 KB)
Female Individual Animal Organ Weight Data (56 KB)
Female Individual Animal Survival Data (33 KB)
Male Individual Animal Body Weight Data (382 KB)
Male Individual Animal Clinical Observations (47 KB)
Male Individual Animal Neoplastic Pathology Data (148 KB)
Male Individual Animal Non Neoplastic Pathology Data (1 MB)
Male Individual Animal Organ Weight Data (56 KB)
Male Individual Animal Survival Data (33 KB)