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TR-571: Kava kava extract (9000-38-8)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-571: Kava kava extract (9000-38-8).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-571: Kava kava extract (9000-38-8).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. TR-571: Kava kava extract (9000-38-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-571 Toxicology and Carcinogenesis Studies of Kava Kava Extract (CASRN 9000-38-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
2-Week Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage
Special Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Special Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in F344/N Rats Exposed via Gavage
Special Evaluation of the Toxicity (C20007) of Kava Kava Extract (9000-38-8) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Kava Kava Extract (9000-38-8) in Micronucleus Study A53705 in B6C3F1 Mice
Genetic Toxicity Evaluation of Kava Kava Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A00186
Summary Data
Genetic Toxicity Evaluation of Kava Kava Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A88186
Summary Data