TR-593: Technical Report Pathology Tables and Curves
Pathology Tables, Survival and Growth Curves from NTP
Short-Term, Long-Term Studies
Revisions to the 2,3-Butanedione Subchronic Study in Rats TDMS Tables: The number of 50 ppm male and female rats with eyes examined microscopically has been updated to 10 for males and 10 for females. No additional diagnoses have been made.
DOI: https://doi.org/10.22427/NTP-DATA-TR-593
DOI: https://doi.org/10.22427/NTP-DATA-TR-593
TR-593: 2,3-Butanedione
Short-Term
3-Month Study Tables - Rats
- E03 - Growth Curves (63 KB)
- E04 - Mean Body Weights and Survival Table (18 KB)
- E05 - Clinical Observations Summary (18 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (37 KB)
- P04 - Neoplasms by Individual Animal (209 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (33 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (243 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (300 KB)
- P14 - Individual Animal Pathology Data (305 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (38 KB)
- P40 - Survival Curves (424 KB)
3-Month Individual Animal Data - Rats
- Female Individual Animal Body Weight Data (34 KB)
- Female Individual Animal Non Neoplastic Pathology Data (99 KB)
- Female Individual Animal Survival Data (11 KB)
- Female Individual Animal Terminal Body Weight Data (18 KB)
- Female Individual Clinical Observations (14 KB)
- Individual Animal Clinical Chemistry Data (31 KB)
- Individual Animal Hematology Data (56 KB)
- Individual Animal Organ Weight Data (13 KB)
- Male Individual Animal Body Weight Data (36 KB)
- Male Individual Animal Non Neoplastic Pathology Data (98 KB)
- Male Individual Animal Survival Data (11 KB)
- Male Individual Animal Terminal Body Weight Data (18 KB)
- Male Individual Clinical Observations (15 KB)
3-Month Study Tables - Mice
- E03 - Growth Curves (430 KB)
- E04 - Mean Body Weights and Survival Table (18 KB)
- E05 - Clinical Observations Summary (18 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (35 KB)
- P04 - Neoplasms by Individual Animal (208 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (33 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (237 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (226 KB)
- P14 - Individual Animal Pathology Data (310 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (36 KB)
- P40 - Survival Curves (425 KB)
3-Month Individual Animal Data - Mice
- Female Individual Animal Body Weight Data (35 KB)
- Female Individual Animal Clinical Observations (13 KB)
- Female Individual Animal Non Neoplastic Pathology Data (118 KB)
- Female Individual Animal Survival Data (11 KB)
- Female Individual Animal Terminal Body Weight Data (18 KB)
- Individual Animal Hematology Data (23 KB)
- Individual Animal Organ Weight Data (11 KB)
- Male Individual Animal Body Weight Data (35 KB)
- Male Individual Animal Clinical Observations (14 KB)
- Male Individual Animal Non Neoplastic Pathology Data (119 KB)
- Male Individual Animal Survival Data (11 KB)
- Male Individual Animal Terminal Body Weight Data (18 KB)
Long-Term
Chronic Study Tables - Rats
- E03 - Growth Curves (69 KB)
- E04 - Mean Body Weights and Survival Table (25 KB)
- E05 - Clinical Observations Summary (24 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (59 KB)
- P04 - Neoplasms by Individual Animal (633 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (46 KB)
- P08 - Statistical Analysis of Primary Tumors (187 KB)
- P08 - Statistical Analysis of Primary Tumors-Custom Nose (22 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (886 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (513 KB)
- P11 - Statistical Analysis of Survival Data (23 KB)
- P14 - Individual Animal Pathology Data (1 MB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (592 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (61 KB)
- P40 - Survival Curves (436 KB)
Chronic Individual Animal Data - Rats
- Female Individual Animal Body Weight Data (359 KB)
- Female Individual Animal Clinical Observations (264 KB)
- Female Individual Animal Neoplastic Pathology Data (116 KB)
- Female Individual Animal Non Neoplastic Pathology Data (944 KB)
- Female Individual Animal Survival Data (33 KB)
- Female Individual Animal Terminal Body Weight Data (56 KB)
- Male Individual Animal Body Weight Data (369 KB)
- Male Individual Animal Clinical Observations (265 KB)
- Male Individual Animal Neoplastic Pathology Data (75 KB)
- Male Individual Animal Non Neoplastic Pathology Data (919 KB)
- Male Individual Animal Survival Data (33 KB)
- Male Individual Animal Terminal Body Weight Data (56 KB)
Chronic Study Tables - Mice
- E03 - Growth Curves (443 KB)
- E04 - Mean Body Weights and Survival Table (24 KB)
- E05 - Clinical Observations Summary (19 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (68 KB)
- P04 - Neoplasms by Individual Animal (731 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (50 KB)
- P08 - Statistical Analysis of Primary Tumors (137 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (932 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (695 KB)
- P11 - Statistical Analysis of Survival Data (24 KB)
- P14 - Individual Animal Pathology Data (1 MB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (617 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (70 KB)
- P40 - Survival Curves (432 KB)
Chronic Individual Animal Data - Mice
- Female Individual Animal Body Weight Data (399 KB)
- Female Individual Animal Clinical Observations (136 KB)
- Female Individual Animal Neoplastic Pathology Data (168 KB)
- Female Individual Animal Non Neoplastic Pathology Data (894 KB)
- Female Individual Animal Survival Data (33 KB)
- Female Individual Animal Terminal Body Weight Data (56 KB)
- Male Individual Animal Body Weight Data (384 KB)
- Male Individual Animal Clinical Observations (82 KB)
- Male Individual Animal Neoplastic Pathology Data (119 KB)
- Male Individual Animal Non Neoplastic Pathology Data (793 KB)
- Male Individual Animal Survival Data (33 KB)
- Male Individual Animal Terminal Body Weight Data (56 KB)